Age - Related Macular Degeneration (AMD)

Also known as: Macular Degeneration, Age Related / Age Related Macular Degeneration (AMD) / Age-Related Macular Degeneration (AMD) / AMD - Age-Related Macular Degeneration / Macular Degeneration, Age-Related / Age-Related Macular Degenerations / Macular Degeneration (Age Related) / Age Related Macular Degeneration (ARMD) / Age - Related Macular Degeneration / Age- Related Macular Degeneration / Age Related Macular Degeneration / Age-Related Macular Degeneration (ARMD) / Age-Related Macular Degeneration / Unspecified macular degeneration / Age-related macular degeneration (disorder) / Macular degeneration senile / Senile macular degeneration / Macular degeneration (senile) of retina, unspecified

Drug	Drug Name	Drug Description
DB15165	Avacincaptad pegol	An RNA aptamer inhibiting the complement C5 indicated for the treatment of geographic atrophy secondary to age-related macular degeneration.
DB00460	Verteporfin	A benzoporphyrin derivative used to treat pathological myopia, ocular histoplasmosis, and choroidal neovascularization in macular degeneration.

Drug	Drug Name	Target	Type
DB15165	Avacincaptad pegol	Complement C5	target

Drug	Drug Name	Phase	Status	Count
DB00878	Chlorhexidine	0	Unknown Status	1
DB11672	Curcumin	0	Completed	1
DB06812	Povidone-iodine	0	Unknown Status	1
DB01270	Ranibizumab	0	Completed	1
DB00162	Vitamin A	0	Completed	1
DB18549	ASP-7317	1	Recruiting	1
DB16081	Acrizanib	1	Completed	1
DB00787	Acyclovir	1	Recruiting	1
DB08885	Aflibercept	1	Unknown Status	1
DB15165	Avacincaptad pegol	1	Completed	2
DB00112	Bevacizumab	1	Recruiting	1
DB05722	CGC-11047	1	Completed	1
DB00822	Disulfiram	1	Not Yet Recruiting	1
DB00095	Efalizumab	1	Withdrawn	1
DB11981	Elamipretide	1	Completed	1
DB12608	Emixustat	1	Completed	1
DB18468	Gildeuretinol	1	Completed	1
DB00646	Nystatin	1	Recruiting	1
DB06056	POT-4	1	Completed	1
DB12812	Palomid 529	1	Completed	2
DB06589	Pazopanib	1	Completed	1
DB06325	Pegpleranib	1	Completed	1
DB06048	RTP-801i	1	Completed	1
DB01270	Ranibizumab	1	Completed	2
DB01270	Ranibizumab	1	Withdrawn	1
DB01015	Sulfamethoxazole	1	Recruiting	1
DB00864	Tacrolimus	1	Recruiting	1
DB00440	Trimethoprim	1	Recruiting	1
DB09033	Vedolizumab	1	Recruiting	1
DB00162	Vitamin A	1	Completed	1
DB06647	Volociximab	1	Completed	1
DB08885	Aflibercept	1 / 2	Completed	1
DB00112	Bevacizumab	1 / 2	Completed	1
DB06322	Carotuximab	1 / 2	Completed	1
DB11981	Elamipretide	1 / 2	Completed	1
DB12577	Fosbretabulin	1 / 2	Completed	1
DB00166	Lipoic acid	1 / 2	Completed	1
DB00137	Lutein	1 / 2	Unknown Status	1
DB11138	Lutein	1 / 2	Unknown Status	1
DB01024	Mycophenolic acid	1 / 2	Recruiting	1
DB19337	Nesvategrast	1 / 2	Completed	1
DB17955	Palucorcel	1 / 2	Completed	1
DB01270	Ranibizumab	1 / 2	Completed	6
DB01270	Ranibizumab	1 / 2	Terminated	2
DB05896	Sirna-027	1 / 2	Completed	1
DB00877	Sirolimus	1 / 2	Completed	2
DB00877	Sirolimus	1 / 2	Terminated	1
DB00864	Tacrolimus	1 / 2	Recruiting	1
DB00620	Triamcinolone	1 / 2	Completed	1
DB11176	Zeaxanthin	1 / 2	Unknown Status	1
DB18549	ASP-7317	2	Withdrawn	1
DB05069	ATG003	2	Completed	1
DB00819	Acetazolamide	2	Completed	1
DB00051	Adalimumab	2	Completed	1
DB08885	Aflibercept	2	Completed	2
DB08885	Aflibercept	2	Terminated	2
DB08885	Aflibercept	2	Unknown Status	1
DB05288	Anecortave acetate	2	Completed	1
DB01076	Atorvastatin	2	Recruiting	1
DB00112	Bevacizumab	2	Completed	4
DB00112	Bevacizumab	2	Terminated	5
DB00484	Brimonidine	2	Completed	1
DB00963	Bromfenac	2	Completed	1
DB00190	Carbidopa	2	Completed	2
DB00190	Carbidopa	2	Terminated	1
DB00190	Carbidopa	2	Withdrawn	1
DB06322	Carotuximab	2	Completed	1
DB11672	Curcumin	2	Recruiting	1
DB00111	Daclizumab	2	Completed	1
DB01234	Dexamethasone	2	Completed	2
DB01234	Dexamethasone	2	Withdrawn	1
DB08908	Dimethyl fumarate	2	Recruiting	1
DB00869	Dorzolamide	2	Completed	1
DB01257	Eculizumab	2	Completed	1
DB11981	Elamipretide	2	Completed	1
DB01590	Everolimus	2	Terminated	1
DB15303	Faricimab	2	Completed	1
DB00591	Fluocinolone acetonide	2	Completed	1
DB00591	Fluocinolone acetonide	2	Terminated	1
DB18860	Galegenimab	2	Terminated	2
DB00065	Infliximab	2	Completed	1
DB16200	Iptacopan	2	Recruiting	1
DB16956	L-Acetylleucine	2	Recruiting	1
DB01235	Levodopa	2	Completed	2
DB01235	Levodopa	2	Terminated	1
DB01235	Levodopa	2	Withdrawn	1
DB00657	Mecamylamine	2	Completed	1
DB00331	Metformin	2	Completed	1
DB01017	Minocycline	2	Completed	1
DB00688	Mycophenolate mofetil	2	Withdrawn	1
DB05650	OT-551	2	Completed	1
DB05650	OT-551	2	Unknown Status	1
DB06325	Pegpleranib	2	Completed	1
DB04216	Quercetin	2	Recruiting	1
DB06048	RTP-801i	2	Completed	1
DB01270	Ranibizumab	2	Completed	15
DB01270	Ranibizumab	2	Terminated	5
DB01270	Ranibizumab	2	Withdrawn	2
DB02709	Resveratrol	2	Recruiting	1
DB00203	Sildenafil	2	Active Not Recruiting	1
DB00203	Sildenafil	2	Terminated	1
DB05896	Sirna-027	2	Terminated	1
DB00877	Sirolimus	2	Completed	2
DB00877	Sirolimus	2	Terminated	1
DB06461	Squalamine	2	Withdrawn	1
DB00864	Tacrolimus	2	Withdrawn	1
DB11926	Tesidolumab	2	Completed	1
DB00373	Timolol	2	Completed	1
DB00620	Triamcinolone	2	Completed	1
DB00620	Triamcinolone	2	Terminated	1
DB00460	Verteporfin	2	Completed	3
DB00460	Verteporfin	2	Withdrawn	1
DB09145	Water	2	Completed	1
DB08885	Aflibercept	2 / 3	Unknown Status	1
DB05288	Anecortave acetate	2 / 3	Completed	1
DB00112	Bevacizumab	2 / 3	Unknown Status	2
DB15303	Faricimab	2 / 3	Recruiting	1
DB04895	Pegaptanib	2 / 3	Completed	2
DB00571	Propranolol	2 / 3	Unknown Status	1
DB01270	Ranibizumab	2 / 3	Completed	1
DB01270	Ranibizumab	2 / 3	Terminated	1
DB01270	Ranibizumab	2 / 3	Unknown Status	1
DB00620	Triamcinolone	2 / 3	Completed	1
DB00620	Triamcinolone	2 / 3	Unknown Status	1
DB08885	Aflibercept	3	Completed	2
DB08885	Aflibercept	3	Not Yet Recruiting	2
DB08885	Aflibercept	3	Terminated	2
DB15165	Avacincaptad pegol	3	Active Not Recruiting	1
DB00112	Bevacizumab	3	Active Not Recruiting	1
DB00112	Bevacizumab	3	Completed	7
DB00112	Bevacizumab	3	Recruiting	1
DB00112	Bevacizumab	3	Terminated	2
DB00112	Bevacizumab	3	Unknown Status	2
DB00112	Bevacizumab	3	Withdrawn	1
DB06642	Bevasiranib	3	Withdrawn	1
DB14864	Brolucizumab	3	Completed	2
DB14864	Brolucizumab	3	Not Yet Recruiting	1
DB14864	Brolucizumab	3	Terminated	1
DB14864	Brolucizumab	3	Withdrawn	1
DB16121	Cemdisiran	3	Not Yet Recruiting	1
DB03756	Doconexent	3	Completed	1
DB11981	Elamipretide	3	Recruiting	1
DB18468	Gildeuretinol	3	Active Not Recruiting	1
DB00159	Icosapent	3	Completed	1
DB00137	Lutein	3	Completed	1
DB11138	Lutein	3	Completed	1
DB04895	Pegaptanib	3	Unknown Status	1
DB06325	Pegpleranib	3	Terminated	3
DB15218	Pozelimab	3	Not Yet Recruiting	1
DB01270	Ranibizumab	3	Active Not Recruiting	1
DB01270	Ranibizumab	3	Completed	15
DB01270	Ranibizumab	3	Recruiting	3
DB01270	Ranibizumab	3	Terminated	2
DB01270	Ranibizumab	3	Unknown Status	4
DB01270	Ranibizumab	3	Withdrawn	1
DB06461	Squalamine	3	Unknown Status	1
DB00460	Verteporfin	3	Completed	2
DB00460	Verteporfin	3	Withdrawn	1
DB00162	Vitamin A	3	Active Not Recruiting	1
DB11176	Zeaxanthin	3	Completed	1
DB08885	Aflibercept	4	Completed	8
DB08885	Aflibercept	4	Recruiting	2
DB08885	Aflibercept	4	Terminated	1
DB08885	Aflibercept	4	Unknown Status	2
DB00112	Bevacizumab	4	Completed	3
DB14864	Brolucizumab	4	Completed	2
DB12460	Conbercept	4	Completed	1
DB12460	Conbercept	4	Unknown Status	1
DB01234	Dexamethasone	4	Completed	1
DB04895	Pegaptanib	4	Completed	1
DB04895	Pegaptanib	4	Terminated	2
DB04895	Pegaptanib	4	Unknown Status	1
DB01270	Ranibizumab	4	Completed	10
DB01270	Ranibizumab	4	Recruiting	1
DB01270	Ranibizumab	4	Terminated	2
DB01270	Ranibizumab	4	Unknown Status	1
DB00460	Verteporfin	4	Completed	3
DB00460	Verteporfin	4	Terminated	1
DB18549	ASP-7317	Not Available	Completed	1
DB08885	Aflibercept	Not Available	Completed	10
DB08885	Aflibercept	Not Available	Recruiting	1
DB00112	Bevacizumab	Not Available	Completed	2
DB00112	Bevacizumab	Not Available	Unknown Status	1
DB14864	Brolucizumab	Not Available	Active Not Recruiting	1
DB14864	Brolucizumab	Not Available	Completed	3
DB00907	Cocaine	Not Available	Completed	1
DB12460	Conbercept	Not Available	Unknown Status	1
DB00465	Ketorolac	Not Available	Completed	1
DB00281	Lidocaine	Not Available	Completed	2
DB14596	Loteprednol etabonate	Not Available	Recruiting	1
DB00218	Moxifloxacin	Not Available	Completed	1
DB11133	Omega-3 fatty acids	Not Available	Active Not Recruiting	1
DB09539	Omega-3-acid ethyl esters	Not Available	Active Not Recruiting	1
DB04895	Pegaptanib	Not Available	Completed	1
DB00807	Proparacaine	Not Available	Completed	2
DB01270	Ranibizumab	Not Available	Completed	10
DB01270	Ranibizumab	Not Available	Unknown Status	5
DB09085	Tetracaine	Not Available	Completed	2
DB00809	Tropicamide	Not Available	Completed	1
DB00460	Verteporfin	Not Available	Unknown Status	1
DB09145	Water	Not Available	Completed	1
DB11176	Zeaxanthin	Not Available	Completed	1