Age - Related Macular Degeneration (AMD) (DBCOND0060543)

Identifiers

Synonyms
Macular Degeneration, Age Related / Age Related Macular Degeneration (AMD) / Age-Related Macular Degeneration (AMD) / AMD - Age-Related Macular Degeneration / Macular Degeneration, Age-Related / Age-Related Macular Degenerations / Macular Degeneration (Age Related) / Age Related Macular Degeneration (ARMD) / Age - Related Macular Degeneration / Age- Related Macular Degeneration / Age Related Macular Degeneration / Age-Related Macular Degeneration (ARMD) / Age-Related Macular Degeneration / Unspecified macular degeneration / Age-related macular degeneration (disorder) / Macular degeneration senile / Senile macular degeneration / Macular degeneration (senile) of retina, unspecified

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Avacincaptad pegol
An RNA aptamer inhibiting the complement C5 indicated for the treatment of geographic atrophy secondary to age-related macular degeneration.
Verteporfin
A benzoporphyrin derivative used to treat pathological myopia, ocular histoplasmosis, and choroidal neovascularization in macular degeneration.
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06582511
Evaluating Metabolic Changes Induced by PhotoBioModulation Through Spectrally Resolved Autofluorescence in Dry Age-Related Macular Degeneration PatientsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05677685
VISUPRIME® Eye DropsNo drug interventionspreventionNot Availablecompleted
NCT05593913
Clinical Evaluation of VeriSee AMD in Screening for Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT05988827
Effect of Minimizing Light Exposure Intensity on Macular Function After Cataract Surgery in Patients With Early or Intermediate AMDNo drug interventionspreventionNot Availablecompleted
NCT05961332
COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Geographic AtrophyNo drug interventionsotherNot Availablerecruiting
NCT02121353
Safety Study of PF582 Versus Lucentis in Patients With Age Related Macular Degenerationtreatment1 / 2completed
NCT00327470
An Open Label Trial to Investigate Macugen for the Preservation of Visual Function in Subjects With Neovascular AMDtreatment4terminated
NCT01542866
A 16 Week Evaluation of the Novartis Health Management Tool (HMT) in Age Related Macular Degeneration (AMD)No drug interventionsotherNot Availablecompleted
NCT02464956
Production of iPSC Derived RPE Cells for Transplantation in AMDNo drug interventionsNot AvailableNot Availablecompleted
NCT05481827
ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent StudyNo drug interventionsother2enrolling_by_invitation
NCT03349801
Development of Novel Clinical Endpoints in Intermediate AMDNo drug interventionsNot AvailableNot Availableunknown_status
NCT05932069
Active AMD Study to Improve Function in VeteransNo drug interventionstreatmentNot Availablerecruiting
NCT01722045
Study to Assess Best Corrected Visual Acuity (BCVA) in Patients With Neovascular Age-Related Macular Degeneration (AMD) Who Are Administered VEGF Trap-Eye (Intravitreal Aflibercept Injection)treatment4completed
NCT02611778
Efficacy and Safety of the Biosimilar Ranibizumab FYB201 in Comparison to Lucentis in Patients With Neovascular Age-related Macular Degenerationtreatment3completed
NCT05110209
Real-world Evaluation of Prevalence of Ocular Adverse Events in Patients With Neovascular (Wet) Agerelated Macular Degeneration (AMD) Who Received Anti-VEGF Agents (IRIS Registry)No drug interventionsNot AvailableNot Availablecompleted
NCT05066685
Characteristics of Patients With Neovascular Age-related Macular Degeneration Enrolled in the Brolucizumab Patient Support Services ProgramNo drug interventionsNot AvailableNot Availablecompleted
NCT02445313
Measuring Geographic Atrophy in AMD Patients Using the Nidek MP-3 Microperimetry DeviceNo drug interventionsNot AvailableNot Availablecompleted
NCT03577041
Medico-economic Evaluation of Anti-VEGF Treatments in the Treatment of naïve Age-related Macular Degeneration (AMD): a Model Adapted to the French ContextNo drug interventionsNot AvailableNot Availablerecruiting
NCT05037396
Evaluation of Number of Patient Eyes That Remained on or Switched to Anti-VEGF Treatment After Initiation of BroluciumabNot AvailableNot Availablecompleted
NCT00647439
Genetics and Markers of Degenerative and Inflammatory Eye DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT05780931
Rehabilitating Vision Loss in Veterans With Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04292080
Long-Term Analysis of DImethyl Fumarate, to Slow the Growth of Areas of Geographic Atrophytreatment2recruiting
NCT01694680
Intervention Trial in Early Age-related Macular DegenerationNo drug interventionstreatmentNot Availablecompleted
NCT06541704
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophytreatment3not_yet_recruiting
NCT05146687
Real-world Evaluation of Prevalence of Ocular Adverse Events in Patients With Neovascular (Wet) Age-related Macular Degeneration (AMD) Who Received Anti-vascular Endothelial Growth Factor (VEGF) Agents (Komodo Health)No drug interventionsNot AvailableNot Availablecompleted
NCT04697953
Efficacy and Safety of Brolucizumab 6mg in a Treat and Extend Regimen in Patients With Neovascular Age-Related Macular Degeneration (nAMD) With Prior Anti-VEGF Exposure (PEREGRINE)treatment3withdrawn
NCT01224847
Intravitreal Injection Anesthesia - Comparison of Different Topical AgentstreatmentNot Availablecompleted
NCT00354445
A Clinical Trial to Explore the Safety and Efficacy of Injections of Macugen When Given Every 6 Weeks in Subjects With AMDtreatment4unknown_status
NCT03859245
Photobiomodulation & Ketogenic Diet for Treatment of Mid-periphery Retinal Disorders for Alzheimer's Disease PreventionNo drug interventionstreatmentNot Availableunknown_status
NCT03690505
Assessment of the Knowledge and Needs of Patients With AMD Before a Therapeutic Patient Education Program is Put in PlaceNo drug interventionssupportive_careNot Availableunknown_status
NCT00902785
A Study Of Early Markers Of Choroidal NeovascularizationNo drug interventionsNot AvailableNot Availableterminated
NCT05082415
Real-world Evaluation of Brolucizumab for the Treatment of Neovascular (Wet) Age-related Macular Degeneration (AMD) (IRIS Study)Not AvailableNot Availablecompleted
NCT02398500
Safety Tolerability and Efficacy of Intravitreal LMG324 in the Treatment of Neovascular Age-Related Macular Degenerationtreatment1 / 2terminated
NCT02348359
X-82 to Treat Age-related Macular Degenerationtreatment2terminated
NCT02022540
Phase 1 Study of Topical Ocular PAN-90806 for Neovascular AMDtreatment1completed
NCT02585401
Evaluation of Physician Knowledge of Safety and Safe Use Information for Aflibercept in CanadaNot AvailableNot Availablecompleted
NCT05111743
Real-world Evaluation of Brolucizumab for the Treatment of Neovascular (Wet) Age-related Macular Degeneration (AMD) (Komodo Health)Not AvailableNot Availablecompleted
NCT03969303
NOTAL-OCT V.2.5 vs Commercial OCT in AMD PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02684578
Metformin for the Minimization of Geographic Atrophy Progression in Patients With AMDtreatment2completed
NCT03794752
Visual Enhancement Device in Low Vision PatientsNo drug interventionssupportive_careNot Availableterminated
NCT04607148
A Study Assessing the Long-Term Safety and Tolerability of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular Degenerationtreatment2terminated
NCT03418220
Comparison of Cytokine Profiles in Aqueous Humor of Patients With Age Related Macular Degeneration (AMD)No drug interventionshealth_services_researchNot Availablecompleted
NCT03972709
A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)treatment2terminated
NCT03038880
Study to Evaluate Faricimab (RO6867461; RG7716) for Extended Durability in the Treatment of Neovascular Age Related Macular Degenerationtreatment2completed
NCT00211484
Treatment of Conditions With Open Label-Anecortave Acetate Sterile Suspension ( 15mg.) Where Lesions do Not Meet Acceptable Criteria for Standard Care.treatment2completed
NCT02875704
Oxidative Stress In Stargardt Disease, Age Related Macular Degeneration and Diabetic RetinopathyNo drug interventionsNot AvailableNot Availableterminated
NCT01499628
EFFECT:Eccentric Fixation From Enhanced Clinical TrainingNo drug interventionstreatmentNot Availablecompleted
NCT04667039
Efficacy, Safety, pharmacokinetiсs, Immunogenicity of GNR-067 and Lucentis®treatment3recruiting
NCT06373731
ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD)treatment3recruiting
NCT02871817
A Comparison of the Checkup Vision Assessment System to Standard Vision Assessment ToolsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01915238
Study of the Effects of Supplements on Eye Disease in Participants From the Age-Related Eye Disease StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00331864
SUSTAIN - Study of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degenerationtreatment3completed
NCT02550002
Comparison of Treatment rOutine Using afLibERcept: Strict vs relAxed retreatmeNT RegimenNot AvailableNot Availablecompleted
NCT00564902
The Zeaxanthin and Visual Function Studysupportive_careNot Availablecompleted
NCT00748384
Usability of the Foresee Home in Intermediate Age Related Macular Degeneration (AMD) PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00277784
High-Resolution Ultrasound Imaging of the Retina and Choroid for Detection on Age Related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT00692887
Correlation Between Visual Field Defects on Foresee Preferential Hyperacuity Perimeter(PHP) and on Optical Coherence Tomography (OCT) in Patients With Choroidal Neovascularization (CNV)No drug interventionsNot AvailableNot Availablecompleted
NCT01846351
Intravitreal Anti-VEGF in Exudative AMD With Epiretinal MembranesNo drug interventionsNot AvailableNot Availablecompleted
NCT00776451
Usability of the PreView PHP for Home Use in Intermediate AMD PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02669953
Aflibercept in Recurrent or Persistent CNVNot AvailableNot Availablerecruiting
NCT02002377
Intravitreal Aflibercept in Wet Age Related Macular Degeneration Patients With an Incomplete Response to Routine Ranibizumab Injectionstreatment4terminated
NCT02218177
Intraocular Cytokines in Non-responders to Ranibizumab Treatment for Neovascular AMDNot AvailableNot Availablecompleted
NCT00358345
PreView PHP Preferential Hyperacuity Perimeter for the Detection of Choroidal NeovascularizationNo drug interventionsNot AvailableNot Availablecompleted
NCT04572698
A Study to Compare LY09004 and Eylea in the Treatment of Wet Age-related Macular Degeneration(wAMD)treatment3unknown_status
NCT02227498
Argus II Retinal Prosthesis System Dry AMD Feasibility Study ProtocolNo drug interventionstreatmentNot Availablecompleted
NCT04779398
Association of MPOD Values With Blue Light.No drug interventionsNot AvailableNot Availablecompleted
NCT01103505
HOme Vision Monitoring in AREDS2 for Progression to Neovascular AMD Using the ForeseeHome DeviceNo drug interventionsdiagnosticNot Availablecompleted
NCT01010997
Foresee Home for Monitoring Age Related Macular Degeneration (AMD)No drug interventionsNot AvailableNot Availablecompleted
NCT01691261
A Study Of Implantation Of Retinal Pigment Epithelium In Subjects With Acute Wet Age Related Macular DegenerationNo drug interventionstreatment1unknown_status
NCT03035461
Patient's Feelings After Receiving a Diagnosis of Age-related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT02140411
Efficacy and Safety of Lucentis® (Ranibizumab Intravitreal Injections) in Chilean Patients With Diabetic Macular Edema.treatment4completed
NCT02174211
A Pharmacokinetic Study: Ranibizumab, Aflibercept and the Effect of Vitrectomy.treatmentNot Availablecompleted
NCT01023971
Macular Function During Anti-VEGF TreatmentNo drug interventionsNot AvailableNot Availableunknown_status
NCT00826371
Evaluation of Safety and Efficacy of Once Monthly Ranibizumab Injections in Chinese Patients With Wet Age Related Macular Degeneration (AMD) Patientstreatment3completed
NCT04740671
A Phase 3 Study to Compare the Efficacy and Safety of HLX04-O With Ranibizumab in Subjects With wAMDtreatment3active_not_recruiting
NCT00457678
Second Line Therapy to Treat Age-related Macular Degeneration (AMD) for Patients Not Responding Well to Lucentis Therapy by Itselftreatment2withdrawn
NCT01880788
Genetic Analysis of Chronic Central Serous Chorioretinopathy Masquerading as Neovascular AMDNo drug interventionsNot AvailableNot Availablecompleted
NCT04794907
Retinal Care Data RepositoryNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03609307
Comparison of Treatment Response to Intravitreal Injection of Combined Propranolol and Bevacizumab Versus Bevacizumab Monotherapy in Patients With Wet Age Related Macular Degeneration :A Clinical Trialtreatment2 / 3unknown_status
NCT04929756
Eye Movement Rehabilitation in Low Vision PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT01361256
Study of WA-NG Telescope Prosthesis in Patients With End-stage Age-related Macular DegenerationNo drug interventionstreatment0withdrawn
NCT03046485
Use of Self-management Group to Improve Quality of Life in Patients With Low VisionNo drug interventionstreatmentNot Availablewithdrawn
NCT00884637
Correlation Between Visual Field Defects on FORESEE HOME and on Optical Coherence Tomography in Choroidal Neovascularization SubjectsNo drug interventionsNot AvailableNot Availablecompleted
NCT04395859
Collateral Damage From the COVID-19 Pandemic Observed in Patients Treated With Intravitreal Injections (IVT) of Anti-angiogenic AgentsNo drug interventionsNot AvailableNot Availablecompleted
NCT01363570
Evaluation of Wet Age-Related Macular Degeneration (AMD) Genetic Profile Interactions With Ranibizumab Treatment OutcomestreatmentNot Availablecompleted
NCT00791570
Anti-VEGFR Vaccine Therapy in Treating Patients With Neovascular MaculopathyNo drug interventionstreatment1completed
NCT01715870
Life Style and Food Habits Questionnaire in the Portuguese Population Aged 55 or MoreNo drug interventionsNot AvailableNot Availablecompleted
NCT00347399
Bevacizumab and Photodynamic Therapy in Neovascular Age Related Macular Degenerationtreatment2terminated
NCT04334499
Mitochondrial DNA in Vitreous Fluid and Blood in Patients With Eye Disease or Ocular Trauma.No drug interventionsNot AvailableNot Availablewithdrawn
NCT04522999
Study of Photobiomodulation Effect on Electroretinogram Outcomes in Dry Age-Related Macular DegenerationNo drug interventionstreatmentNot Availablecompleted
NCT01581606
Evaluation of TeleOphthalmology in AMD-TeleMedicine Solutions to Improve Patient Access and Quality of Vision OutcomesNo drug interventionsNot AvailableNot Availablecompleted
NCT03750149
Reading Analysis in Ophthalmologic PatientsNo drug interventionsdiagnosticNot Availableunknown_status
NCT04778436
Macula Evolution in Patients With AMD Taking Oral Food SupplementationNo drug interventionsotherNot Availablecompleted
NCT00713518
Phase II Open Label Multicenter Study For Age Related Macular Degeneration Comparing PF-04523655 Versus Lucentis In The Treatment Of Subjects With CNV (MONET Study).treatment2completed
NCT01521819
Iray for Vascularized Pigment Epithelial Detachment (VPED) Secondary to Age Related Macular DegenerationtreatmentNot Availableunknown_status
NCT03963817
Snapshot Camera for AMDNo drug interventionsNot AvailableNot Availablerecruiting
NCT03117634
An Open Label-study to Compare the Efficacy of Aflibercept Monotherapy for Polypoidal Choroidal Vasculopathytreatment4completed
NCT02868424
Treatment of Age-related Macular Degeneration by Fetal Retinal Pigment Epithelial Cells TransplantationNo drug interventionstreatment0unknown_status
NCT05698316
A Collaborative Resource of Heidelberg Multimodal Imaging of Intermediate and Early Atrophic AMD Cases to Study Prediction of Disease ProgressionNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00776763
Ocular Growth Factors Profile in Proliferative Retinopathies Before and After Intravitreal Bevacizumabtreatment2completed
NCT00963339
Age-Related Macular Degeneration (AMD) - Usability StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT01327222
Intravitreal Bevacizumab for Low Vision in Neovascular Age-related Macular Degeneration (AMD)treatment3completed
NCT03927430
Surgical Outcome of Macular Membrane Peeling Associated With Significant Macular DrusenNo drug interventionsNot AvailableNot Availablecompleted
NCT00556348
Intravitreal Bevacizumab for Choridal Neovascularization Secondary to Age-Related Macular Degenerationtreatment4completed
NCT03038048
30g vs 33g Needle for Intravitreal InjectionsNo drug interventionstreatmentNot Availablecompleted
NCT00347165
Intravitreal Bevacizumab for Age-Related Macular Degenerationtreatment2terminated
NCT01453920
Wet AMD Recurrence Rate in Patients Stable on Three Month Ranibizumab Dosingtreatment4completed
NCT01822873
Study on Visual Function Impairments in Dry Age-related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT02173873
Ziv-aflibercept in Eyes With Retinal Diseases and Poor Vision-phase Itreatment1unknown_status
NCT01632527
Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Age-Related Macular Degeneration (AMD)No drug interventionstreatment1 / 2completed
NCT02903576
Stem Cell Therapy for Outer Retinal DegenerationsNo drug interventionstreatment1 / 2completed
NCT03630562
Assay of Pro-angiogenic Cytokines in Exudative Age-Related Macular DegenerationNo drug interventionsotherNot Availablecompleted
NCT02725762
Study of Photobiomodulation to Treat Dry Age-Related Macular DegenerationNo drug interventionstreatmentNot Availablecompleted
NCT00710229
Manta Study: Avastin Versus Lucentis in Age Related Macular Degenerationtreatment3unknown_status
NCT03823092
Polarization Perception in Health and Disease. Testing a New Sight TestNo drug interventionsNot AvailableNot Availableunknown_status
NCT00406744
Efficacy of Retreatments With Intravitreal Bevacizumabtreatment3terminated
NCT02296567
Comparison of Pharmacokinetics of and Effect on Systemic VEGF Levels in Age Related Macular Degeneration Patientsbasic_science2 / 3unknown_status
NCT03326401
The Potential Role of Dietary Antioxidant Capacity on Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT03313401
Effect of Aflibercept on Human Corneal Endothelial Cells in Neovascular Age-Related Macular DegenerationNot AvailableNot Availablecompleted
NCT01348672
Prospective Study Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human EyeNo drug interventionsNot AvailableNot Availableunknown_status
NCT00569569
Retaane® in Age-Related Macular Degenerationtreatment2 / 3completed
NCT05287269
Ocular Coherence Tomography During Cataract AssessmentNo drug interventionsNot AvailableNot Availablecompleted
NCT02055612
Mobile Clinic - a Cross-sectional Epidemiological SurveyNo drug interventionsNot AvailableNot Availablecompleted
NCT03760055
Assessment of Visual Function With a Portable Brain-computer InterfaceNo drug interventionsNot AvailableNot Availableunknown_status
NCT03409250
SD-OCT-guided Intravitreal Ranibizumab Treatment in Choroidal Neovascularization Due to Myopiatreatment4completed
NCT00603850
Testing the Effectiveness of the Interactive Tutorial of the Home Macular Perimeter (HMP)No drug interventionsNot AvailableNot Availablecompleted
NCT02556723
Intravitreal Injections of Ziv-aflibercept for Macular DiseasestreatmentNot Availablecompleted
NCT00902408
Effect of Lutein-enriched-egg Beverage on Age-Related Macular Degeneration (AMD)No drug interventionspreventionNot Availablecompleted
NCT02016508
Safety Study of Use of Autologous Bone Marrow Derived Stem Cell in Treatment of Age Related Macular DegenerationNo drug interventionstreatment1 / 2unknown_status
NCT00390208
Triple Therapy - PDT Plus IVD and Intravitreal Ranibizumab Versus Lucentis Monotherapy to Treat Age-Related Macular Degenerationtreatment2completed
NCT00864838
Oral Acetazolamide, Brimonidine Tartarate, and Anterior Chamber Paracentesis for Ocular Hypertension Control After Intravitreal Bevacizumabtreatment2completed
NCT03772938
Stem Cells Therapy in Degenerative Diseases of the RetinaNo drug interventionsother1unknown_status
NCT01301443
Phase I Dose Escalation Safety Study of RetinoStat in Advanced Age-Related Macular Degeneration (AMD)No drug interventionstreatment1completed
NCT04005443
Molecular Imaging Exploration of Ocular Angiogenic Activity and Evaluation of Its Interest in the Therapeutic Follow-up of Patients With AMD (Age-related Macular Degeneration)No drug interventionsdiagnosticNot Availablerecruiting
NCT01731964
Study of WA-NG Telescope Prosthesis in Patients With End-stage Age-related Macular DegenerationNo drug interventionstreatmentNot Availablewithdrawn
NCT00275821
Efficacy and Safety of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)treatment3completed
NCT04169802
Study Evaluating Retinal Health Monitoring System Visual Acuity Module.No drug interventionsNot AvailableNot Availablecompleted
NCT03205202
Cataract and AMD in a Trial of a Multivitamin and Cocoa ExtractNo drug interventionsprevention4unknown_status
NCT05005884
Possible Effects of Supplement Therapy With Oral Phenolics on Cluster of Differentiation 163 (CD-163) Biomarker of Patients With Age-related Macular DegenerationNo drug interventionsdiagnostic1unknown_status
NCT03415984
Prevalence of Age Related Macular Degeneration (ARMD) in Parkinson's Patients and Assesment of the Role of L-DOPANo drug interventionsNot AvailableNot Availablecompleted
NCT03056079
Cytokine and Visual Outcome Variations in Eyes Receiving Aflibercepttreatment4unknown_status
NCT03278587
Village-Integrated Eye Worker Trial II - PilotNo drug interventionspreventionNot Availablecompleted
NCT00734487
AREDS 2 Ancillary Spectral Domain Optical Coherence Tomography StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00446654
Safety of 16.5 mg (3.3%) CGC-11047 Once Every 2 Weeks vs. Once Every 4 Weeks in Patients With CNV Due to AMDtreatment1completed
NCT03275753
Visual Function Tests in Age-related Macular DegenerationNo drug interventionsNot AvailableNot Availableterminated
NCT05003245
Compare the Efficacy and Safety of HLX04-O With Ranibizumab in Subjects With wAMDtreatment3unknown_status
NCT01243645
MP-1 Biofeedback: Pattern Stimulus Versus Audio-feedback in AMDNo drug interventionsNot AvailableNot Availablecompleted
NCT00595998
Sensitivity and Specificity of the Home Macular Perimeter (HMP)No drug interventionsNot AvailableNot Availablecompleted
NCT03076697
Smartphone Screening for Eye DiseasesNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT02681783
PRedictive Factors and Changes From Treatment in iPCV Versus CSR Versus nAMD With afLibercepttreatment4unknown_status
NCT04779411
Online Validation of Dietary Intake Food Frequency Questionnaire Over Four Weeks, and Electronic Device Use Questionnaire Over Eight Weeks.No drug interventionsNot AvailableNot Availablecompleted
NCT02438111
The Role of the Gut Metagenome on the Development of Age Related Macular Degeneration (AMD)No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04895293
RBM-007 in Treatment naïve Exudative Age-related Macular DegenerationNo drug interventionstreatment1 / 2completed
NCT00604071
Sensitivity of the Home Macular Perimeter (HMP)No drug interventionsNot AvailableNot Availablecompleted
NCT04920071
Optimising Visual Acuity Measurement in Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT00596388
Usage of the Home Macular Perimeter (HMP)No drug interventionsNot AvailableNot Availablecompleted
NCT01336907
Comparison Between Home Macular Perimeter and Optical Coherence Tomography (OCT) Visual Field Defects in Patients With Choroidal Neovascularization (CNV)No drug interventionsNot AvailableNot Availablewithdrawn
NCT01115556
A Pilot Study to Evaluate the Role of High-dose Ranibizumab (2.0mg) in the Management of AMD in Patients With Persistent/Recurrent Macular Fluid Less Than 30 Days Following Treatment With Intravitreal Anti-VEGF Therapy (the LAST Study)treatment1 / 2completed
NCT02909985
Visual Activity Evoked by Infrared in Humans After Dark AdaptationNo drug interventionsdiagnosticNot Availablecompleted
NCT01025232
A Study of Intravitreal Injections of 2.0mg Ranibizumab in Subjects With Chronic Fluid On OCT Post Multiple Injections With Ranibizumab (Super-dose Anti-VEgf SAVE Trial)treatment1 / 2terminated
NCT04993352
Evaluate the Safety and Efficacy of HLX04-O in Subjects With wAMDNo drug interventionstreatment1 / 2completed
NCT03451500
Carbidopa-Levodopa in Dry AMD With Geographic Atrophytreatment2terminated
NCT01914159
Ranibizumab In Pigment Epithelium Tears Secondary To Age-Related Macular Degeneration Studytreatment2completed
NCT02521142
Non-invasive Optical Angiography in Age-related Macular DegenerationNo drug interventionsNot AvailableNot Availablerecruiting
NCT01541449
Plaqenil Role in Prevention of Age Related Macular DegenerationNo drug interventionsNot AvailableNot Availableunknown_status
NCT01644513
Evaluation of the Association Between Genetic Load and Response to Anti-VEGF Therapy in AMD PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04739319
Project AMD: Comprehensive Characterisation of Age-Related Macular Degeneration and Its ProgressionNo drug interventionsNot AvailableNot Availablerecruiting
NCT00809419
A Study of the NeoVista Ophthalmic System for the Treatment of Subfoveal CNV Associated With Wet AMD in Patients That Require Persistent Anti-VEGF TherapyNo drug interventionstreatment1 / 2unknown_status
NCT04761341
FLIO and the Influence of Oral Lutein Supplementation on Macular PigmentNo drug interventionsprevention4completed
NCT01634841
Walnuts and Healthy AgingNo drug interventionspreventionNot Availablecompleted
NCT02441816
VITAL - Individualising Therapy for Neovascular AMD With Aflibercepttreatment4completed
NCT04590196
Effect of Oral Curcumin Supplementation in Dry Age-related Macular Degeneration (AMD) Patientstreatment0completed
NCT02173496
Colour Contrast Sensitivity for the Early Detection of Wet Age-related Macular Degereration (CEDAR)No drug interventionsNot AvailableNot Availablecompleted
NCT01943396
Treatment of AMD With Rheohemapheresis /RHF/No drug interventionstreatment4unknown_status
NCT00331435
PDT Study for Exudative AMD With PCVNo drug interventionstreatment4completed
NCT00992563
WALTZ - Wet Age-Related Macular Degeneration (AMD) AL-39324 Treatment Examinationtreatment2completed
NCT01626339
Effect of Intravitreal Anti-VEGF on Retinal Vessels DiameterNot AvailableNot Availableunknown_status
NCT00993330
Macular Pigment Optical Density in Healthy SubjectsNo drug interventionsNot AvailableNot Availableterminated
NCT04187157
Association Between Light Spectrum and Survival After Cataract SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT00592826
HMP (Home Macular Perimeter) -Usability TrialNo drug interventionsNot AvailableNot Availablecompleted
NCT00726466
Study of Efalizumab Combined With Intravitreal Ranibizumab in the Treatment of Age-Related Macular Degenerationtreatment1withdrawn
NCT01255774
Serial Retinal Thickness Changes And Scotoma Size Measured With Lucentis Therapytreatment3unknown_status
NCT03845582
Phase 3 Study of ALK-001 in Geographic Atrophytreatment3active_not_recruiting
NCT04468373
Study of WA-NG (NG-IMT) Telescope Prosthesis in Patients With End-stage Age-related Macular DegenerationNo drug interventionstreatmentNot Availableterminated
NCT01272076
Cirrus HD-OCT Measurement of Area of Increased Light Penetration Under the Retinal Pigment Epithelium (RPE)No drug interventionsNot AvailableNot Availablecompleted
NCT01334294
Home Vision Monitoring Using the ForeseeHome Device Following Treatment of Neovascular Age Related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT01516294
IRay to Treat Polypoidal Choroidal Vasculopathy (PCV) Secondary to Age-Related Macular Degeneration (AMDNo drug interventionstreatmentNot Availableunknown_status
NCT04863391
Telemedicine in Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availableunknown_status
NCT00557791
Safety & Efficacy Study Evaluating the Combination of Bevasiranib & Lucentis Therapy in Wet AMD (CARBON)treatment3withdrawn
NCT03222362
Pars Plana Vitrecromy in Patients Aged 85 Years and AboveNo drug interventionsNot AvailableNot Availablecompleted
NCT01670162
On-label tReatment With Intravitreal Aflibercept injectiOn for Patients With Persistent Pigment epitheliaL Detachments in Neovascular Age Related Macular Degeneration (AMD)treatment4unknown_status
NCT00413829
Immediate Effects of Lucentis® in Conjunction With Photodynamic Therapy With Visudyne® in Exudative AMD(IECOMB)treatment2completed
NCT04689789
OCTA and Retinal Angiomatous ProliferationNo drug interventionsNot AvailableNot Availablecompleted
NCT00931489
Retinal and Retinal Pigment Epithelium (RPE) Autoimmunity in Age-related Macular Degeneration (AMD)treatment2completed
NCT01073592
Comparison Between Foresee Home and Optical Coherence Tomography (OCT) Visual Field Defects in Patients With Choroidal Neovascularization (CNV)No drug interventionsNot AvailableNot Availablecompleted
NCT03056092
Cytokine and Visual Outcome Variations in Eyes Receiving Ranibizumabtreatment4unknown_status
NCT03446144
Safety and Efficacy of IONIS-FB-Lrx in up to 120 Patients 55 and Older With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)No drug interventionstreatment2withdrawn
NCT03504540
Comparison of Complement Factors and Genetic Polymorphisms of AMD Between Patients With Systemic Lupus Erythematosus (SLE) With and Without Retinal "Pseudo-drusen-like" Deposits: Case-control Study (PL-AMD)No drug interventionsNot AvailableNot Availablecompleted
NCT03393767
Time Course of Activity Signs at SD-OCT High Frequency Intravitreal Ranibizumab Treatment in CNV Due to AMDtreatment4completed
NCT01170767
French Evaluation Group Avastin Versus Lucentistreatment3completed
NCT00376701
Combination Therapy for Age-Related Macular Degeneration.treatment2completed
NCT02567604
Development of Core Outcomes for Age-related Macular Degeneration (AMD) Interventions- Caregivers' PerspectiveNo drug interventionsNot AvailableNot Availablecompleted
NCT01543568
Study for Recalcitrant Age Related Macular Degenerationtreatment4completed
NCT01014468
Bevacizumab Versus Ranibizumab in Age Related Macular Degenerationtreatment3unknown_status
NCT01657669
Short-term Clinical Effects of Intravitreal Aflibercept Injection 2.0mg as a Predictor of Long-term Resultstreatment4unknown_status
NCT00729846
Bevacizumab in Combination With Visudyne Photodynamic Therapy (PDT)treatment2completed
NCT00800995
Superoxide Dismutase (SOD) as Antioxidant Treatment OF Age Related Macular Degeneration (ARMD)No drug interventionsprevention3completed
NCT04697095
Survival of Monocytes Collected From Patients With Atrophic AMD in Retinal Pigmented Epithelium ExplantsNo drug interventionshealth_services_researchNot Availablerecruiting
NCT00593450
Comparison of Age-related Macular Degeneration Treatments Trials: Lucentis-Avastin Trialtreatment3completed
NCT00605423
The MAP Study: Fluocinolone Acetonide (FA)/Medidur (TM) for Age Related Macular Degeneration (AMD) Pilottreatment2completed
NCT01570608
Lucentis KAV Studytreatment3completed
NCT00359008
PHP Home Preferential Hyperacuity Perimeter for the Detection of Choroidal Neovascularization (CNV)No drug interventionsNot AvailableNot Availablecompleted
NCT03102138
Retinal Pigment Epithelium Safety Study For Patients In B4711001No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01991730
Observational Study to Evaluate and Compare the Rate and Extent of Inflammation After a Single Injection of Ranibizumab vs. a Single Intravitreal Injection of Aflibercept in Treatment Naive and Treatment Experienced PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02779686
PIIR Study: Comparison of Genetic Tests for Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availableterminated
NCT00288561
Study of Ranibizumab Administered in Conjunction With Photodynamic Therapy With Verteporfin in Patients With Subfoveal Choroidal Neovascularization and Age-Related Macular Degenerationtreatment2completed
NCT06583109
Prediction Model of Treatment Efficacy for Age-related Macular Degeneration Based on Multi-source Imaging ModalitiesNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05735730
Can the Risk for AMD be Modulated?No drug interventionsdiagnosticNot Availablerecruiting
NCT00348543
Prophylactic Laser Treatment of Drusen MaculopathyNo drug interventionspreventionNot Availablecompleted
NCT02332343
Sparing of the Fovea in Geographic Atrophy ProgressionNo drug interventionsNot AvailableNot Availablecompleted
NCT00140803
Study Of Combined VISUDYNE Therapy With Kenalog In CNV Secondary To Age-Related Macular Degenerationtreatment2completed
NCT01570790
Combretastatin A4 Phosphate in Patients With Neovascular Age-Related Macular Degenerationtreatment1 / 2completed
NCT01830790
Effects of Sildenafil on Choroidal Thickness in AMDhealth_services_research2terminated
NCT02599064
Evaluating RXI-109 to Reduce the Progression of Subretinal Fibrosis in Subjects With NVAMDNo drug interventionstreatment1 / 2unknown_status
NCT03710564
Study of Safety and Efficacy of Brolucizumab 6 mg Dosed Every 4 Weeks Compared to Aflibercept 2 mg Dosed Every 4 Weeks in Patients With Retinal Fluid Despite Frequent Anti-VEGF Injectionstreatment3terminated
NCT05686421
Comfortable and Stabilizing Chin & Forehead Rest Attachment for Slit Lamp ConfigurationsNo drug interventionssupportive_careNot Availablecompleted
NCT05437302
Effectiveness of Prism Spectacles in Patients With Age Related Macular DegenerationNo drug interventionssupportive_careNot Availablecompleted
NCT03166202
Age-Related Macular Degeneration, Scotopic Dysfunction, and Driving Performance in a SimulatorNo drug interventionsNot AvailableNot Availablecompleted
NCT04693702
Observational Study of Vision Improvement in Patients With Retinal DisordersNo drug interventionsNot AvailableNot Availablecompleted
NCT00403884
Selective RPE Laser Treatment (SRT) for Various Macular DiseasesNo drug interventionstreatmentNot Availableunknown_status
NCT01777984
Impact of Visceral Fat on the Pathogenesis of Age-related Macular DegenerationNo drug interventionsNot AvailableNot Availableunknown_status
NCT03633084
RBM-007 in Subjects witH ExudatIve Age-related Macular DegenerationNo drug interventionstreatment1 / 2completed
NCT05672979
Prospective triAl of Modified Treat-and-extend Regimens With BroLucizumab in pachychOroid Neovasculopathytreatment3not_yet_recruiting
NCT06164587
Evaluation of Kamuvudine-8 in Subjects With Geographic AtrophyNo drug interventionstreatment1recruiting
NCT01245387
Observational Study Of The Long-Term Effect Of Macugen In Patients With Wet Age-Related Macular DegenerationNot AvailableNot Availablecompleted
NCT05914233
Non-invasive Ultrasound Retinal Stimulation for Vision RestorationNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03011554
Telescope Exchange StudyNo drug interventionssupportive_careNot Availableunknown_status
NCT03668054
Safety and Clinical Effectiveness of Intravitreal Bevacizumab (Lumiere®) in Patients With Wet Age-related Macular Degeneration (Wet AMD)treatment3completed
NCT00342251
Investigating Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT02873351
A Safety and Efficacy Study of Carbidopa-levodopa in Patients With Macular Degenerationtreatment2withdrawn
NCT02951351
Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal InjectionsotherNot Availablecompleted
NCT00527553
The Effect of Eggs and Egg Products on Macular PigmentNo drug interventionspreventionNot Availablecompleted
NCT03834753
A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)treatment3completed
NCT06572553
Evaluation of Therapeutic Efficacy of Faricimab for Clinical AMD, DME, and RVO Patientstreatment2 / 3recruiting
NCT01918553
Cohort Study on the Age-related Macular Degeneration: Incidence and Research for Predisposing FactorsNo drug interventionsdiagnosticNot Availablecompleted
NCT03466177
Multimodal Retinal Imaging in the Detection and Follow-up of Alzheimer's DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT02337647
Evaluation of the Distortion Correction Data Collection (DCDC) App SoftwareNo drug interventionsbasic_scienceNot Availablecompleted
NCT04796545
Post-market Clinical Investigation of the SING IMT System, Model NG SI IMT 3X in Patients With End-stage Age-related Macular DegenerationNo drug interventionsotherNot Availablerecruiting
NCT02401945
A Safety and Efficacy Study of DE-120 Injectable Solution for Age-related Macular Degenerationtreatment2completed
NCT01316198
Effects of Xanthophylls on Optical DensityNo drug interventionspreventionNot Availablecompleted
NCT00680498
Combination Lucentis and Ocular Photodynamic Therapy With Visudyne, With Evaluation-based Retreatmenttreatment4completed
NCT05615805
The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal InjectionsNo drug interventionssupportive_careNot Availablecompleted
NCT05959005
Progression of Early Atrophic LesionsNo drug interventionsNot AvailableNot Availablerecruiting
NCT05536297
Avacincaptad Pegol Open-Label Extension for Patients With Geographic Atrophytreatment3active_not_recruiting
NCT03242083
Evaluate the Quality of Life of Patients With AMDNo drug interventionsNot AvailableNot Availablecompleted
NCT02960828
"Stop Early Age-related Macular Degeneration (AMD) From Vision Loss Eternally" StudyNo drug interventionstreatmentNot Availableunknown_status
NCT01226628
A Safety Study of CNTO 2476 in Patients With Age-Related Macular Degenerationtreatment1 / 2completed
NCT00443911
Rheohemapheresis and Lutein Supplementation in the Non-Exsudative Form of Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availableunknown_status
NCT00782093
A Phase 1 Ascending and Parallel Group Trial to Establish the Safety, Tolerability and Pharmacokinetics Profile of Volociximab (Alpha 5 Beta 1 Integrin Antagonist) in Subjects With Neovascular Age- Related Macular Degenerationtreatment1completed
NCT01866371
High Resolution Retinal ImagingNo drug interventionsNot AvailableNot Availablerecruiting
NCT00879671
Effects of Lutein Supplementation on Macular Pigment Optical Density and Visual Acuity in Patients With Age-related Macular DegenerationNo drug interventionspreventionNot Availablecompleted
NCT04894071
QA102 Phase 1 Study in Healthy Young and Older Adult SubjectsNo drug interventionstreatment1completed
NCT00357578
Genetic Study of Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT04516278
A 3-month Study to Assess the Safety of ONS-5010 in Subjects With Visual Impairment Due to Retinal Disorderstreatment3completed
NCT03478878
Vitamin A Palmitate Supplementation in Patients With Reticular Pseudodrusen (RPD) and Delayed Dark Adaptationtreatment0completed
NCT02762188
Genetic Biomarkers for the Response to Anti-VEGF (Vascular Endothelial Growth Factor).Treatment in Wet Age-related Macular Degeneration (Wet ARMD)No drug interventionsbasic_scienceNot Availablecompleted
NCT00951288
Effect of Saffron Supplementation on Macular Cone-mediated Function in Age-related Macular DegenerationNo drug interventionsprevention1 / 2unknown_status
NCT01174407
Implication of CD35, CD21 and CD55 in Exudative Age-related Macular DegenerationNo drug interventionsNot AvailableNot Availableunknown_status
NCT01397409
Evaluation of AGN-150998 in Exudative Age-related Macular Degeneration (AMD)treatment2completed
NCT02800356
Subthreshold Laser Treatment for Reticular Pseudodrusen and Geographic Atrophy Secondary to AMDNo drug interventionstreatmentNot Availablecompleted
NCT02452385
Phase 1 Study of CM082 in Patients With wAMDNo drug interventionstreatment1suspended
NCT03946085
Evaluation of a New Eye-specific Multivitamin Formula in Participants at Risk of Age-related Macular Degeneration (AMD)No drug interventionspreventionNot Availablecompleted
NCT02137915
Long-Term Follow-up Safety Study of Human Central Nervous System Stem Cells in Subjects With Geographic Atrophy of Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availableterminated
NCT01835015
Pharmacokinetics of CLG561 in Patients With Advanced Age-Related Macular DegenerationNo drug interventionsbasic_science1completed
NCT02308215
Retinal Therapy Guided by 3D OCT Image AnalysisNo drug interventionsNot AvailableNot Availablecompleted
NCT05893537
Study to Evaluate the Efficacy and Safety of Oral CT1812 in Participants With Geographic Atrophy (GA) Secondary to Dry Age-Related Macular Degeneration (AMD).No drug interventionstreatment2recruiting
NCT01186432
Preliminary Safety and Efficacy of the PDS-1.0 in Patients With Neovascular Age Related Macular Degeneration (AMD)No drug interventionstreatment1completed
NCT00090532
A Study Of The Safety And Efficacy Of AG-013,958 In Subjects With Subfoveal Choroidal Neovascularization Associated With Age-Related Macular DegenerationNo drug interventionstreatment1 / 2terminated
NCT01136252
Intravitreal Adalimumab in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degenerationtreatment2completed
NCT01782352
Age-related Macular Degeneration (AMD) in the Vitamin D and Omega-3 Trial (VITAL)preventionNot Availableactive_not_recruiting
NCT01940900
A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® Monotherapytreatment3terminated
NCT03571100
Comfort and Antimicrobial Efficacy of Chlorhexidine vs Betadine for Intravitreal Injectionsprevention0unknown_status
NCT00251459
A Study to Evaluate Ranibizumab in Subjects With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)treatment3completed
NCT03023059
Dose Ranging Study of Carbidopa-levodopatreatment2completed
NCT05494775
Effect of Corona Virus on Intravitreal InjectionsNo drug interventionstreatmentNot Availableunknown_status
NCT01352975
Study of Dark Adaptation in Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03891875
ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With Non-central GAtreatment2completed
NCT06351670
Personalised Monitoring of Early and Intermediate Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease ProgressionNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01271270
Palomid 529 in Patients With Neovascular Age-Related Macular Degenerationtreatment1completed
NCT01577342
Determining the Effect of Antibiotic Drop Prophylaxis on the Conjunctival FlorapreventionNot Availablecompleted
NCT01531842
A Research Study to Evaluate the Effects of Repeated Intravitreal Injections on Bacteria Around the EyeNo drug interventionssupportive_careNot Availableunknown_status
NCT02314299
A Study of MTP-131 Topical Ophthalmic Solution in Subjects With Diabetic Macular Edema and Non-Exudative Intermediate Age-related Macular Degenerationtreatment1 / 2completed
NCT03882606
Implantation of SML in Patients With Dry Age-related Macular Degeneration and Myopic MaculopathyNo drug interventionstreatmentNot Availableunknown_status
NCT00347906
Photodynamic Therapy (PDT) Versus Transpupillary Thermotherapy (TTT) in Occult Choroidal Neovascularization (CNV) in Age-related Macular Degeneration (AMD)No drug interventionsNot AvailableNot Availableterminated
NCT02555306
A Phase I/II Safety, Tolerability, Immunogenicity, and Bioactivity Study of DE-122 Injectable Solution for Refractory Exudative Age-related Macular Degenerationtreatment1 / 2completed
NCT01676506
Genetic Polymorphisms in Ranibizumab Treatment in Wet Age-Related Macular Degeneration (AMD)treatmentNot Availableunknown_status
NCT02829606
Head Mounted Eye Tracking Aide for Loss of Central Vision (HETALCEV)No drug interventionssupportive_careNot Availablecompleted
NCT04196049
Removal of Massive Subretinal Organized Blood Clot With FragmatomeNo drug interventionsNot AvailableNot Availablecompleted
NCT01339949
Study to Evaluate the Safety and Effectiveness of IRay in Wet Age-related Macular Degeneration (AMD) Patients With Recurrent Leakage Secondary to Choroidal Neovascularisation (CNV)No drug interventionstreatmentNot Availablewithdrawn
NCT03178149
A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degenerationtreatment1recruiting
NCT04268836
Vision Improvement for Patients With Age-Related Macular DegenerationNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05251636
Adjunct Episcleral Brachytherapy for PCVtreatment3not_yet_recruiting
NCT00401713
Transplantation of Autologous RPE Versus Translocation of Autologous RPE and Choroid in AMDNo drug interventionstreatmentNot Availablecompleted
NCT06046118
Photobiomodulation in Dry Age Related Macular DegenerationNo drug interventionstreatmentNot Availablerecruiting
NCT02225119
The Focal Electro-Oculogram in Macular DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00787319
Long-Term Non-Interventional Study (NIS) To Investigate The Safety And Effectiveness Of MACUGEN In Patients With Neovascular Age-Related Macular Degeneration Under Conditions Of Routine Clinical PracticeNo drug interventionsNot AvailableNot Availablecompleted
NCT05667441
Adherence to Lifestyle Changes for Age-related Macular DegenerationNo drug interventionspreventionNot Availableactive_not_recruiting
NCT03011541
Stem Cell Ophthalmology Treatment Study IINo drug interventionstreatmentNot Availablerecruiting
NCT05678517
Seven-year Outcomes Following Intensive Anti-VEGF Therapy in Wet AMDNo drug interventionsNot AvailableNot Availablecompleted
NCT03211234
Study Assessing the Efficacy and Safety of Intravitreal Injections of DE-122 in Combination With Lucentis® Compared to Lucentis® Monotherapy in Wet Age-related Macular Degeneration Subjectstreatment2completed
NCT03024424
Value of Genetic Counseling and Testing for Patients Who Would Like to Know More About Their Personal Risk of AMDNo drug interventionspreventionNot Availablecompleted
NCT00797524
Function and Structure Imaging in Different Retinal Diseases: Retinal Leakage Analyzer Versus Optical Coherence TomographyNo drug interventionsNot AvailableNot Availablecompleted
NCT04356716
Sildenafil for Treatment of Choroidal Ischemiatreatment2active_not_recruiting
NCT02372916
Geographic Atrophy and Intravitreal Ranibizumab InjectionsNot AvailableNot Availableunknown_status
NCT02226835
Study of Retinal Findings in People With Signs and Symptoms of Alzheimer s Disease Enrolled in 09-M-0198No drug interventionsNot AvailableNot Availableterminated
NCT00891735
A Study of Ranibizumab Administered Monthly or on an As-needed Basis in Patients With Subfoveal Neovascular Age-related Macular Degeneration (HARBOR)treatment3completed
NCT04679935
Efficacy and Safety of Two Different Brolucizumab 6 mg Dosing Regimens in Neovascular Age-related Macular Degenerationtreatment4completed
NCT04735263
Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMDtreatment2unknown_status
NCT03848663
Visual Remapping to Aid Reading With Field LossNo drug interventionstreatmentNot Availablerecruiting
NCT03128463
Pharmacogenomic Study on Anti-VEGF Medicine in Treatment of Macular Neovascular DiseasesNot AvailableNot Availableunknown_status
NCT02941263
Natural History of Geographic Atrophy Associated With Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT05913063
Direct Discrimination of Quantum States by the Human EyeNo drug interventionsdiagnosticNot Availablerecruiting
NCT05062486
A Study to Evaluate the Safety and Efficacy of RQC for AMDtreatment2unknown_status
NCT02868086
The Impact of Two Strategies in the Monitoring of Exudative ARMD on the Visual Acuity (by OCT B Scan or OCT Angiography)No drug interventionsdiagnosticNot Availablecompleted
NCT05991986
Preparation of Patient Autologous Induced Pluripotent Stem Cell-derived Retinal Cells for AMDNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01944839
A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® Monotherapytreatment3terminated
NCT00478439
Investigation of Macular Pigment Augmentation on Dark AdaptationNo drug interventionsNot Available4terminated
NCT02035722
Intravitreal Injections-related AnxietyNo drug interventionsprevention2 / 3completed
NCT01824225
Study of PRN and Every 2months Intravitreal Aflibercept for Age Related Macular Degenerationtreatment4completed
NCT01496625
National Eye Institute Biorepository for Retinal DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
NCT01833325
Proton Radiation Therapy for Macular DegenerationNo drug interventionstreatmentNot Availablecompleted
NCT01948830
Randomized Study for Efficacy and Safety of Ranibizumab 0.5mg in Treat-extend and Monthly Regimens in Patients With nAMDsupportive_care3completed
NCT01445548
Sirolimus for Advanced Age-Related Macular Degenerationtreatment1 / 2completed
NCT02387957
A 24 Month Phase 2a Open Label, Randomized Study of Avastin®, Lucentis®, or Eylea® (Anti-VEGF Therapy) Administered in Combination With Fovista® (Anti-PDGF BB Pegylated Aptamer)treatment2terminated
NCT02802657
Efficacy and Safety of "Treat-and-Extend" Regimen Versus "Pro Re Nata" of Conbercept in Age-related Macular Degenerationtreatment4unknown_status
NCT06351657
Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease ProgressionNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03935126
Global Atrophie Biomarker Evaluation Study (GABiE)No drug interventionsNot AvailableNot Availableterminated
NCT05433766
Patient-centred Smartphone AI for Protecting Vision in Macular DiseaseNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT05635266
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research InitiativesNo drug interventionsNot AvailableNot Availablerecruiting
NCT00991666
Association Between Laser Interferometric Measurement of Fundus Pulsation and Pneumotonometric Measurement of Pulsatile Ocular Blood Flow in Patients With Age-related Macular DegenerationNo drug interventionsbasic_scienceNot Availablecompleted
NCT01521065
An Open-label Study to Evaluate the Clinical and Economic Benefits of I-Ray in Patients With Choroidal Neovascularization Secondary to Age-related Macular DegenerationNo drug interventionstreatment2unknown_status
NCT01553474
Blood and Saliva Sample Collection for AREDS 2No drug interventionsNot AvailableNot Availablecompleted
NCT05757674
Analysis of the Intestinal Microbiome in Patients With Wet Age-related Macular DegenerationNo drug interventionsNot AvailableNot Availablerecruiting
NCT03844074
A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)treatment3completed
NCT05391074
Oral Postbiotics in Patients With Macular AtrophyNo drug interventionstreatmentNot Availableunknown_status
NCT06330220
Visual Function Change in Wet Age-related Macular Degeneration Patients With Better Baseline Visual Acuitytreatment4completed
NCT02563782
Study to Evaluate Sub-retinal Transplantation of Retinal Pigmented Epithelial Cells in Patients With Dry AMDtreatment2withdrawn
NCT03225131
Dark Adaptation in Participants With Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availablerecruiting
NCT02130531
Pharmacokinetic and Pharmacodynamic Study of Emixustat in Subjects With Geographic Atrophy Associated With Dry Age-Related Macular Degenerationtreatment1completed
NCT02118831
Systemic Pharmacokinetics Following Intravitreal Injections of Anti-VEGFbasic_science1 / 2completed
NCT06489873
Lutein, Zeaxathin, and Fish Oil SupplementationNo drug interventionsotherNot Availablerecruiting
NCT06333873
Impact of Age-related Macular Degeneration on Daily Living ActivitieNo drug interventionsotherNot Availablenot_yet_recruiting
NCT01256827
Seven Year Update of Macular Degeneration PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00791427
ERG/EOG Study in AMD Patients Treated With RanibizumabNot AvailableNot Availablecompleted
NCT05984927
NG101 AAV Gene Therapy in Subjects With Wet Age-Related Macular DegenerationNo drug interventionstreatment1 / 2recruiting
NCT00345176
Age-Related Eye Disease Study 2 (AREDS2)treatment3completed
NCT01013376
A Pilot Study of the Safety of MC-1101 in Both Normal Volunteers and Patients With Early Dry AMDNo drug interventionstreatment1completed
NCT02625376
Resveratrol for Exudative Age-Related Macular DegenerationNo drug interventionspreventionNot Availableterminated
NCT01042860
The Influence of Lutein Supplements on Age-related Macular DegenerationNo drug interventionspreventionNot Availablecompleted
NCT02261194
Effect of a Self-care Intervention on Depression in People With Age-related Macular Degeneration or Diabetic RetinopathyNo drug interventionstreatmentNot Availablecompleted
NCT00568191
Stratus Versus Cirrus OCT in AMDNo drug interventionsNot AvailableNot Availableunknown_status
NCT00712491
Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular Degenerationtreatment1 / 2terminated
NCT02102880
The Role of Complement Factor H Polymorphism in the Regulation of Choroidal Vascular Tone in Young Healthy SubjectsNo drug interventionsotherNot Availableunknown_status
NCT05772780
MP-3 Biofeedback Training and Central Vision LossNo drug interventionstreatmentNot Availablecompleted
NCT02462889
IAI Versus Sham as Prophylaxis Against Conversion to Neovascular AMDprevention2unknown_status
NCT02358889
Study Evaluating Intravitreal hI-con1™ in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degenerationtreatment2completed
NCT03150589
A Study to Compare SB11 (Proposed Ranibizumab Biosimilar) to Lucentis in Subjects With Neovascular Age-related Macular Degeneration (AMD)treatment3completed
NCT02286089
Safety and Efficacy Study of OpRegen for Treatment of Advanced Dry-Form Age-Related Macular DegenerationNo drug interventionstreatment1 / 2active_not_recruiting
NCT00393692
Fundus Autofluorescence Imaging in Age-related Macular Degeneration Using Confocal Scanning Laser OphthalmoscopyNo drug interventionsNot AvailableNot Availablecompleted
NCT01402544
Clinical Assessment Of Age-related Macular Degeneration Patients After Early Diagnosis and Treatment With Ranibizumabtreatment2 / 3terminated
NCT05262244
Targeted Fluorescence Imaging in AMDdiagnostic1recruiting
NCT02463344
Long Term Follow Up of Sub-retinal Transplantation of hESC Derived RPE Cells in Patients With AMDNot AvailableNot Availablecompleted
NCT01177644
Safety and Preliminary Efficacy Study of PDS-1.0 in Patients With Neovascular AMDNo drug interventionstreatment1withdrawn
NCT05390840
A Study to Investigate the Effect on Central Macular Thickness of Treatment With MG-O-1002 Eye Drops in Participants Aged Over 45 With Neovascular Age-related Macular Degeneration (nAMD)No drug interventionstreatment2recruiting
NCT05763940
Efficacy of OmegaBoost to Increase Omega-3 Levels in Healthy IndividualsNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT03752840
Village-Integrated Eye Worker Trial IINo drug interventionsscreeningNot Availablerecruiting
NCT01165801
Size Progression of Macular Degeneration After Cataract SurgeryNo drug interventionsprevention4completed
NCT02022501
A Phase I/II Safety Study of DE-120 Injectable Solution for Age-related Macular DegenerationNo drug interventionstreatment1 / 2completed
NCT05187104
Treatment of Age-related Macular Degeneration Using Retinal Stem and Progenitor CellsNo drug interventionstreatment1 / 2unknown_status
NCT01573572
Extension Study to Gather Data on Effect of Macugen on the Corneal Endotheliumother4completed
NCT02864472
Comparison of PDT Combination With Ranibizumab vs. Ranibizumab Monotherapy in Persistent PCV With Initial Loading DoseNot Available4unknown_status
NCT05441072
Validation of Bulbicam for DR- and AMD-patientsNo drug interventionsNot AvailableNot Availablecompleted
NCT05963646
Optical Coherence Tomography and Microperimetry Biomarker Evaluation in Patients With Geographic Atrophy StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00599846
The Natural History of Geographic Atrophy Progression (GAP) StudyNo drug interventionsNot AvailableNot Availableterminated
NCT06518512
Automated Vision Assessment and Impairment Detection Through Gaze Analysis in Wet AMD PatientsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00001310
Tissue Studies of Human Eye DiseasesNo drug interventionsNot AvailableNot Availableterminated
NCT00517010
Pilot Study of Lucentis Combined With Proton Beam Irradiation in Treating Wet Age-related Macular Degenerationtreatment0completed
NCT05542381
The Role of Loteprednol in Reducing Post-Intravitreal Injection Related PaintreatmentNot Availablerecruiting
NCT02255981
Efficacy of Acupuncture in Macular DiseasesNo drug interventionstreatmentNot Availablecompleted
NCT06458595
Safety and Tolerability of KH658 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)No drug interventionstreatment1 / 2not_yet_recruiting
NCT00279695
Ultrasonic Evaluation of Ocular TissuesNo drug interventionsNot AvailableNot Availableunknown_status
NCT00813514
Does Vascular Endothelial Growth Factor (VEGF) or Complement Factor H Gene Polymorphism Play a Role in the Treatment Success With VEGF Inhibitors in Patients With Choroidal NeoVascularization (CNV)?No drug interventionsdiagnosticNot Availablewithdrawn
NCT01337414
Tools to Optimize Patient Presentation After Onset of Exudative Age-Related Macular Degeneration (AMD)No drug interventionsdiagnosticNot Availableterminated
NCT00556114
A Pilot Study of Functional Optical Coherence Tomography for Ocular ImagingNo drug interventionsNot AvailableNot Availablecompleted
NCT05447650
Microcurrent Stimulation Therapy for Nonexudative Age-related Macular Degeneration (i-SIGHT)No drug interventionsotherNot Availableactive_not_recruiting
NCT01108250
LOC387715/HTRA1 Variants in Polypoidal Choroidal Vasculopathy in a Korean PopulationNo drug interventionsbasic_scienceNot Availablecompleted
NCT01464723
Study EvAluating Genotypes While Using Lucentis 2treatment4completed
NCT02126423
Resistance to Antibiotics in Patients Receiving Eye InjectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT01830608
Risk Factors for Drusen ProgressionNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03104608
Automatic Self Transcending Meditation (ASTM) for Patients With Severe Age Related Macular Degeneration (AMD)No drug interventionssupportive_careNot Availableunknown_status
NCT00950638
A Study of ARC1905 (Anti-C5 Aptamer) in Subjects With Dry Age-related Macular Degenerationtreatment1completed
NCT01692938
Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLONo drug interventionsNot AvailableNot Availablecompleted
NCT05662943
Outcomes of Tolerating Subretinal Fluid in Type 1 MNV and PCVNot AvailableNot Availablecompleted
NCT04836143
Eyes That Do Not Meet the Eligibility Criteria of Clinical Trials on Age-Related Macular Degeneration: Proportion of the Real-World Patient Population and Reasons for ExclusionNo drug interventionsNot AvailableNot Availablecompleted
NCT04142164
Computer-based Tutorial and Automated Speech Recognition for Intravitreal Drug InjectionsNo drug interventionsotherNot Availableunknown_status
NCT01799564
Micropulse Laser for Geographic AtrophyNo drug interventionstreatmentNot Availablecompleted
NCT05672121
Safety and Tolerability of KH631 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)No drug interventionstreatment1 / 2recruiting
NCT00734721
Assessment of Psychological Strain and Perioperative Fear in Intravitreal InjectionsNo drug interventionsother2completed
NCT01033721
Phase I Study of Palomid 529 a Dual TORC1/2 Inhibitor of the PI3K/Akt/mTOR Pathway for Advanced Neovascular Age-Related Macular Degenerationtreatment1completed
NCT01790802
Laser Intervention in Early Age-Related Macular Degeneration StudyNo drug interventionspreventionNot Availablecompleted
NCT03869684
A Study to Assess the Safety, Tolerability and Effectiveness of MT-0814 for the Treatment of Age-related Macular DegenerationNo drug interventionstreatment2terminated
NCT03838679
Imaging of the Angiofibrotic Switch in Neovascular AMDNo drug interventionsNot AvailableNot Availableunknown_status
NCT01115387
GARM II: A Study on the Genetics of Age-related MaculopathyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01940887
A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Either Avastin® or Eylea® Compared to Avastin® or Eylea® Monotherapytreatment3terminated
NCT02291887
Genetic Analysis of Patients Responsive to Ranibizumab But Resistant to AfliberceptNot AvailableNot Availablecompleted
NCT00805233
Combination Ranibizumab and Bromfenac for Neovascular Age-related Macular Degenerationtreatment2completed
NCT06015633
Ocular, Vascular, and Genetic Findings in AMD PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00304954
Infliximab, Sirolimus and Daclizumab to Treat Age-Related Macular Degenerationtreatment2completed
NCT01773954
Repeated Eye Injections of Aflibercept for Treatment of Wet Age Related Macular DegenerationtreatmentNot Availablecompleted
NCT00533754
Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian PopulationNo drug interventionsbasic_scienceNot Availableunknown_status
NCT00148551
Triamcinolone Acetonide as an Adjunctive to VPDT in ARMD.treatment2 / 3unknown_status
NCT02088151
Selective Retinal Pigment Epithelium Laser Therapy for Macular Disease of the RetinaNo drug interventionstreatmentNot Availableterminated
NCT02090751
Development of a Device to Measure Dark AdaptationNo drug interventionsNot AvailableNot Availablecompleted
NCT02140151
Prophylactic Ranibizumab for Exudative Age-related Macular Degenerationprevention1 / 2completed
NCT01269151
Ranibizumab Short- and Log-term Effects on Retinal Function in wAMDdiagnosticNot Availablecompleted
NCT02626377
Multicenter Prospective Cohort of Informal Caregivers in Burgundy and Franche-ComtéNo drug interventionsotherNot Availableterminated
NCT00329277
Detection of Topographic Residual Acuity in Patients With Age Related Macular DegenerationNo drug interventionsdiagnosticNot Availablecompleted
NCT06125977
Impact of Non-Exudative Type 1 MNV on AMD ProgressionNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00788177
Subretinal Macugen® for Neovascular Age-Related Macular Degenerationtreatment3unknown_status
NCT06264947
Efficacy of Laser Acupuncture on Zanzhu (BL02) for Dry Age-related Macular DegenerationNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT01083147
Age-Related Macular Degeneration (AMD) - Beta Study Telemedicine AssessmentNo drug interventionsNot AvailableNot Availablecompleted
NCT00464347
TAC-PF, Avastin® in Combination With Photodynamic Therapy to Treat Age Related Macular Degenerationtreatment2terminated
NCT01876147
Visual and Functional Assessment in Low Vision PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT05752045
OphtAI Diagnostic Performance Validation for Automated Screening of Eye DiseasesNo drug interventionsscreeningNot Availablerecruiting
NCT01080898
Evaluation of Optical Coherence Tomography.No drug interventionsNot AvailableNot Availablecompleted
NCT01528605
Effects of Lutein and Zeaxanthin Supplementation on Early Age-related Macular DegenerationNo drug interventionspreventionNot Availablecompleted
NCT01330797
The Effect of Ranibizumab on Eye Lens Opacity in Cases With Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT00890097
Geographic Atrophy Treatment EvaluationNo drug interventionstreatment3terminated
NCT05222997
Therapy of Age-related Macular DegenerationNo drug interventionsNot AvailableNot Availableunknown_status
NCT00321997
A Clinical Trial to Explore Safety and Efficacy of Different Doses of Pegaptanib Sodium, Compared to Sham, in Patients With Wet AMD.treatment2 / 3completed
NCT00935883
Complement Inhibition With Eculizumab for the Treatment of Non-Exudative Macular Degeneration (AMD)treatment2completed
NCT05112861
A 3-month Study to Compare the Safety of ONS-5010 in Vials Versus Pre-filled Syringe in Subjects With Visual Impairment Due to Retinal Disorderstreatment3active_not_recruiting
NCT00831961
Antibiotic Resistant Patterns of Conjunctival and Nasophayngeal Flora After Repeated Exposure to Topical AntibioticsNo drug interventionsNot AvailableNot Availablecompleted
NCT00473928
Safety of Intravitreal POT-4 Therapy for Patients With Neovascular Age-Related Macular Degeneration (AMD)treatment1completed
NCT02214628
Phase 2A Open Label Safety Study of Fovista® (Anti-PDGF BB) Regimen Administered in Combination With Anti-VEGF Therapy to Study Sub-Retinal Fibrosis in Neovascular AMDNo drug interventionstreatment2terminated
NCT01233128
Vascular Endothelial Growth Factor (VEGF) & LOC387715/HTRA1 Polymorphism in Polypoidal Choroidal VasculopathyNo drug interventionsNot AvailableNot Availablecompleted
NCT02230228
Phase 1 Safety Study of ALK-001 in Healthy Volunteersbasic_science1completed
NCT01148511
Comparison of Safety, Effectiveness and Quality of Life Outcomes Between Labeled Versus "Treat and Extend" Regimen in Turkish Patients With Choroidal Neovascularisation Due to Age-related Macular Degeneration (AMD)treatment4completed
NCT06391411
Effect of Micronutrient Supplementation on the Intestinal Microbiota in Patients With Age-related Macular Degeneration - The Gut-Retina-axis StudyNo drug interventionstreatmentNot Availablecompleted
NCT06190093
A 3-month Study to Assess the Safety and Effectiveness of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)treatment3recruiting
NCT01640171
Anesthesia Preference for Intravitreal Injection: Topical or SubconjunctivaltreatmentNot Availablecompleted
NCT05710471
Treatment of Recalcitrant Neovascular AMD Using Brolocizumab With Immediate T&Etreatment4completed
NCT00455871
Study of Treatment Effects of Combination Therapy of Lucentis Plus Reduced Fluence PDT With Visudyne in Patients With Exudative AMDtreatmentNot Availableunknown_status
NCT02588378
The Role of Inflammation in AMD and Related DisordersNo drug interventionsNot AvailableNot Availableunknown_status
NCT00470678
EXTEND III - Efficacy and Safety of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)treatment3completed
NCT02564978
Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated With Age-Related Macular Degenerationtreatment2completed
NCT06178978
Device for Age-related Macular Degeneration (AMD)No drug interventionsNot AvailableNot Availablecompleted
NCT00306488
OT-551 Antioxidant Eye Drops to Treat Geographic Atrophy in Age-Related Macular Degenerationtreatment2completed
NCT01319188
Ranibizumab and the Risk of Arterial Thromboembolic Eventsscreening4terminated
NCT06347107
Robotic Subretinal tPA Injection StudyNo drug interventionstreatmentNot Availablerecruiting
NCT02577107
Head to Head Study of Anti-VEGF Treatment.basic_science4completed
NCT01032109
Photodynamic Therapy Alone Versus Combined With Intravitreal Bevacizumab for Age-related Macular DegenerationtreatmentNot Availablecompleted
NCT04087356
Age-related Macular Degeneration (AMD) and Cardiovascular DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT04292756
Triamcinolone Acetonide in Patients With Serous Pigment Epithelial DetachmentNo drug interventionstreatmentNot Availablecompleted
NCT02510885
SD-OCT AngiographyNo drug interventionsotherNot Availableterminated
NCT05803785
Safety of BBC1501 Intravitreal Injection in Patients With Neovascular Age-Related Macular Degeneration (nAMD)No drug interventionstreatment1not_yet_recruiting
NCT05220085
Beovu Experience UZ LeuvenNot AvailableNot Availableunknown_status
NCT01233115
LOC387715/HTRA1 and the Combined Photodynamic Therapy With Intravitreal Bevacizumab in Polypoidal Choroidal VasculopathyNo drug interventionsNot AvailableNot Availablecompleted
NCT00769015
Low Vision Depression Prevention Trial for Age Related Macular DegenerationNo drug interventionsprevention3completed
NCT05355415
Adaptive Optics Imaging of Outer Retinal DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
NCT01996215
Brain Connectivity in Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT01717937
Comparison of Phase-variance Optical Coherence Tomography and Fluorescein Angiography in Retinovascular ImagingNo drug interventionsNot AvailableNot Availableterminated
NCT00135837
Photodynamic Therapy in Occult-Only Lesions (POOL)treatment4completed
NCT00766337
Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular Degenerationtreatment2terminated
NCT05230537
A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degenerationtreatment2recruiting
NCT05438732
Multicenter Clinical Study of the SING-IMT in Patients With Late-stage AMDNo drug interventionsotherNot Availablerecruiting
NCT06394232
Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.treatment1 / 2recruiting
NCT05465252
Effect of Omega-3 Fatty Acid Supplementation on Dry-AMD ProgressionNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04005352
Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON)treatment3completed
NCT01527500
Intravitreal LFG316 in Patients With Age-related Macular Degeneration (AMD)treatment2completed
NCT04278300
Study of the Discriminating Power of a Blood Biomarker for Omega-3 Polyunsaturated Fatty Acid Content of the Retina for Age-related Macular Degeneration (AMD)No drug interventionsNot AvailableNot Availablecompleted
NCT01480700
Consumption of Eggs Rich in Lutein and Omega-3 Fatty Acids on the Macular PigmentNo drug interventionspreventionNot Availablecompleted
NCT00857259
The Efficacy of Oral Everolimus in Patients With Neovascular Age-related Macular Degenerationtreatment2terminated
NCT02707575
Cytokeratin 8 Level in Age-related Macular DegenerationNot AvailableNot Availablecompleted
NCT00215670
Study of the Safety, Tolerability and Pharmacokinetics of 1 Mg/Eye and 3 Mg/Eye Pegaptanib Sodium in Patients With Exudative Age-Related Macular Degeneration (AMD)treatment2 / 3completed
NCT03552770
Single or Combined Protocols for NV-AMDhealth_services_research4completed
NCT03079570
Flicker Fusion Thresholds Between Young and Old Subjects at Various Luminance LevelsNo drug interventionsNot AvailableNot Availablecompleted
NCT02357342
Sirolimus Versus Anti-Vascular Endothelial Growth Factor (antiVEGF) for Wet AMDtreatment2completed
NCT00805649
Combined Therapy in Age-Related Macular Degeneration (ARMD)treatment4completed
NCT00766649
Pilot Study of the Evaluation of Subconjunctival Sirolimus in the Treatment of Bilateral GA Associated With AMDtreatment1 / 2completed
NCT04241536
Metabolomics: A Novel Tool for Investigating the Pathogenesis of Age-related Macular DegenerationNo drug interventionsotherNot Availablecompleted
NCT02848313
An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects With Intermediate Age-Related Macular Degenerationtreatment1completed
NCT02511613
Effect of Squalamine Lactate Ophthalmic Solution, 0.2% in Subjects With Neovascular Age-Related Macular Degenerationtreatment2withdrawn
NCT00695318
Fluocinolone Acetonide Intravitreal Inserts in Geographic Atrophytreatment2terminated
NCT00627718
Assessment of Macular Edema Using HRT TechniqueNo drug interventionsdiagnosticNot Availableunknown_status
NCT03022318
Carbidopa-levodopa in Neovascular AMDtreatment2completed
NCT02076919
First-in-Human Study of LHA510 in Elderly Subjects and Patients With Age-Related Macular Degenerationbasic_science1completed
NCT00801541
Characterization of Early Markers of Choroidal NeovascularizationNo drug interventionsNot AvailableNot Availablecompleted
NCT02345317
Reticular Pseudodrusen Progression StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01089517
A Safety and Efficacy Study of E10030 (Anti-PDGF Pegylated Aptamer) Plus Lucentis for Neovascular Age-Related Macular Degenerationtreatment2completed
NCT00539734
Changes in Retinal Function After Intravitreal Ranibizumab for Age-related Macular DegenerationtreatmentNot Availablecompleted
NCT02467634
Study of HUCNS-SC Subretinal Transplantation in Subjects With GA of AMDNo drug interventionstreatment2terminated
NCT05200624
Subthreshold Laser Treatment in Intermediate Age-related Macular Degeneration With Nascent Geographic Atrophy StudyNo drug interventionstreatmentNot Availablerecruiting
NCT02130024
A Comparison of Ranibizumab and Aflibercept for the Development of Geographic Atrophy in (Wet) AMD Patientstreatment4completed
NCT02748824
Five-year Incidence of Age-related Macular Degeneration in the Central Region of PortugalNo drug interventionsNot AvailableNot Availablecompleted
NCT05300724
An Observational Study of the Progression of Intermediate Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02248324
Association of Previously Verified Gene Polymorphisms With AMD in Turkish PopulationNo drug interventionsNot AvailableNot Availableunknown_status
NCT05265624
The Moran AMD Genetic Testing Assessment StudyNo drug interventionsprevention2completed
NCT06213896
Detecting Eye Diseases Via Hybrid Deep Learning Algorithms From Fundus ImagesNot AvailableNot Availablecompleted
NCT06381596
Retinal Fundus Flavoprotein Fluorescence in Age Related Macular DegenerationNo drug interventionsotherNot Availablerecruiting
NCT01638858
Treatment of Diabetic Macular Edema With 0.5mg Intraocular Ranibizumab (Lucentis)diagnosticNot Availablecompleted
NCT06087458
Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular DegenerationNo drug interventionstreatment1 / 2recruiting
NCT04891835
Analysis of naïve Patients With Age-related Macular Degeneration of the Neovascular Type and Treated With Aflibercept (Eylea®) in "Treat-and-extend" at CHU BrugmannNo drug interventionsNot AvailableNot Availablecompleted
NCT03710863
Safety and Tolerability of Oral CM082 in Patients With wAMDNo drug interventionstreatment2unknown_status
NCT02224963
Macular Degeneration and Aging StudyNo drug interventionspreventionNot Availablecompleted
NCT04486963
A Phase Ⅱ Clinical Study of Sanhuangjingshimingwan in Wet( Neovascular)Age-related Macular Degeneration(wAMD) SubjectsNo drug interventionstreatment2completed
NCT00725686
Study of PF-04523655 (REDD14NP) In Subjects With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (Wet AMD)treatment1completed
NCT02914639
Safety and Exploratory Efficacy Study of SF0166 in the Treatment of Neovascular Age-Related Macular Degeneration (AMD)treatment1 / 2completed
NCT00572039
Improving Function in Age-Related Macular DegenerationNo drug interventionstreatment3completed
NCT05196139
Visual Outcome After Vitrectomy With Subretinal tPA InjectionNo drug interventionsNot AvailableNot Availablecompleted
NCT06241625
Virtual Reality Based Vision Test in Patients With AMDNo drug interventionsdiagnosticNot Availablerecruiting
NCT06355830
Intermediate Age-related Macular Degeneration - Multimodal Analysis and Longitudinal StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00305630
Neovascular Age Related Macular Degeneration (AMD), Periocular Corticosteroids, and Photodynamic Therapy (PDT)treatment2 / 3completed
NCT01650948
Genetic Load and Phenotype in Aggressive AMDNo drug interventionsNot AvailableNot Availablecompleted
NCT00395057
A Study Using Intravitreal Injections of a Small Interfering RNA in Patients With Age-Related Macular Degenerationtreatment2terminated
NCT05569226
OKKO Health Hyperacuity, Contrast and Colour Game Validation in Age-related Macular DegenerationNo drug interventionsNot AvailableNot Availablerecruiting
NCT03954626
Study to Collect Safety and ECG Data on Brolucizumab 6 mg Intravitreal Treatment in Patients With Wet AMDtreatment3completed
NCT00390026
The Avastin vs Visudyne for Neovascular AMD Studytreatment3withdrawn
NCT02717026
Multimodal Imaging of Retinal VesselsNo drug interventionsNot AvailableNot Availablecompleted
NCT04482465
Omega 3 and Vitamin D Dosage in a Population With Moderate to High Risk of AMDNo drug interventionspreventionNot Availablecompleted
NCT05064865
Impact of Regular Consumption of Grapes on Eye Health in Singapore Older AdultsNo drug interventionspreventionNot Availableactive_not_recruiting
NCT01298674
Epidemiological Study of the Prevalence of Age-Related Macular Degeneration in PortugalNo drug interventionsNot AvailableNot Availablecompleted
NCT06076720
Evaluation of New Head-mounted Visual Aids Among Patients With Low VisionNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00463320
A Study To Evaluate The Safety, Tolerability And Pk Of Pazopanib Eye Drops In Healthy Adult And Elderly Subjects.diagnostic1completed
NCT03374020
Retinal Imaging Using NOTAL-OCTNo drug interventionsNot AvailableNot Availablecompleted
NCT04018482
Povidone Iodine vs AVEnova: A Pre-injection Disinfection Study (PAVE Study)No drug interventionstreatment4completed
NCT01682382
Association of Macular Pigment Optical Density (MPOD) and Genetic Variants in Complement Factor H in Subjects With Choroidal Neovascular (CNV)No drug interventionsNot AvailableNot Availablecompleted
NCT05941273
A Study of the SING IMT in an Israeli CohortNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01846273
Visual Outcome in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV) Treated With Either Ranibizumab as Monotherapy or Combined With Verteporfin Photodynamic Therapy (vPDT)treatment4completed
NCT01016873
INTREPID - IRay Plus Anti-VEGF Treatment For Patients With Wet AMDNo drug interventionstreatment2completed
NCT06237127
Effects of Goji vs. Fiber on Macular DegenerationNo drug interventionssupportive_careNot Availablerecruiting
NCT00709527
ARC1905 (ANTI-C5 APTAMER) Given Either In Combination Therapy With Lucentis® 0.5 mg/Eye In Subjects With Neovascular Age-Related Macular Degenerationtreatment1completed
NCT01048476
Effects of Lutein and Zeaxanthin Supplementation on Age-related Macular Degenerationtreatment1 / 2unknown_status
NCT05091476
OcuDyne System in the Treatment of AMDNo drug interventionstreatmentNot Availablerecruiting
NCT02422160
Vision Outcomes Using Quantitative Optical Coherence Tomography Evaluation in Age Related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT00590694
Lucentis for Age-related Macular Degeneration Pigment Epithelial Detachmentstreatment2 / 3completed
NCT00485394
The OMEGA Study: Use of Eye Drops to Treat Geographic Atrophy Associated With Age-Related Macular Degeneration (Dry AMD)treatment2unknown_status
NCT05427994
Assessing the Quality of Life and Social Support in Age-Related Macular Degeneration PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01778491
AMD Phenotype and Genotype StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT05587062
Efficacy and Safety of Aflibercept in Patients With Neovascular Age-related Macular Degenerationtreatment3completed
NCT00429962
Study Comparing Ranibizumab Monotherapy With Combined Verteporfin Therapy in Subfoveal CNVtreatment3completed
NCT01217762
Safety & Tolerability of the IRay System in Subjects With Exudative Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)No drug interventionstreatment1unknown_status
NCT05690880
ForeseeHome NRich RegistryNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03030729
Macular Thickness Measurements Using Retinal-thickness OCTNo drug interventionsNot AvailableNot Availablecompleted
NCT00987129
Omega 6:Omega 3 Ratio and Progression of Age-related Macular Degeneration (AMD).No drug interventionsNot AvailableNot Availableterminated
NCT00423189
Lucentis Utilizing Visudyne (LUV Trial) Combination Therapy in the Treatment of Age-Related Macular Degenerationtreatment4terminated
NCT02302989
Prophylactic Ranibizumab for Exudative Age-Related Macular Degenerationprevention1 / 2completed
NCT03092492
AMD Ryan Initiative Study (ARIS)No drug interventionsNot AvailableNot Availablecompleted
NCT05380492
Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular DegenerationNo drug interventionstreatment1 / 2active_not_recruiting
NCT00500344
CAPTAIN:Choroidal Neovascularization Assessment by Pattern Electroretinographytreatment1completed
NCT00569140
A Phase 1, Safety, Tolerability and Pharmacokinetic Profile of Intravitreous Injections of E10030 (Anti-PDGF Pegylated Aptamer) in Subjects With Neovascular Age-Related Macular Degenerationtreatment1completed
NCT05507840
Photobiomodulation for Dry Age Related Macula DegenerationNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04112667
Functionally Validated Structural Endpoints for Early AMDNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05703867
Transpalpebral Microcurrent Stimulation for the Improvement of Visual Acuity in Patients With Macular DegenerationNo drug interventionstreatment1 / 2completed
NCT00134667
Macugen (Pegaptanib Sodium) Alone, Versus Macugen in Combination With PDT (Photodynamic Therapy) With Visudyne (Verteporfin) in Patients With Age-Related Macular Degeneration (AMD)treatment4terminated
NCT03725501
Evaluation of the Safety and Efficacy of ALS-L1023 Administered in Combination With Ranibizumab in Patients With Wet-AMDtreatment2completed
NCT01879501
Living Successfully With Chronic Eye DiseasesNo drug interventionshealth_services_researchNot Availableunknown_status
NCT05657301
Safety and Tolerability of KH631 Gene Therapy in Participants With Neovascular Age-related Macular DegenerationNo drug interventionstreatment1recruiting
NCT04101604
Biomarkers of Common Eye DiseasesNo drug interventionsNot AvailableNot Availableunknown_status
NCT04269304
Deciphering AMD by Deep Phenotyping and Machine Learning- Prospective Study - PINNACLENo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT06319872
The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degenerationtreatment1not_yet_recruiting
NCT00594672
Age-Related Eye Disease Study (AREDS) Follow-UpNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02613572
Alpha Lipoic Acid in Geographic Atrophytreatment1 / 2completed
NCT02571972
Dorzolamide-timolol Drops With Injections to Treat AMD, RVO or DME.treatment2completed
NCT01678872
A Follow-up Study to Evaluate the Safety of RetinoStat® in Patients With Age-Related Macular DegenerationNo drug interventionsother1active_not_recruiting
NCT01162746
Comparison of Ranibizumab Monotherapy and Ranibizumab Combination Therapies in Recurrent or Persistent Choroidal Neovascularization Secondary to Age-related Macular Degenerationtreatment2completed
NCT04151212
A Phase I Clinical Trial of BAT5906 Injection in Patients With Wet Age-related Macular DegenerationNo drug interventionstreatment1completed
NCT06465212
Personalized Shared Eye-care Identification of Age-related Macular Degeneration Using Artificial Intelligence and Telemedicine by Matching Optometrist Office-based Sites With Clinical SupervisionNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04659512
Recurrent Neovascular Age-related Macular Degeneration After Therapy SuspensionNo drug interventionsNot AvailableNot Availablecompleted
NCT04276610
Words on the Brain: Can Reading Rehabilitation for Age-Related Vision Impairment Improve Cognitive Functioning?No drug interventionstreatmentNot Availableterminated
NCT01464710
Genetic Assessment of Early to Late Macular Degeneration StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT01546181
Retinal Imaging by Adaptive Optics in Healthy Eyes and During Retinal and General DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT06174181
Preventive TREatment of Dry Eye in Patients Receiving Repeated Intravitreal Injections for Age-related Macular DegenerationNo drug interventionspreventionNot Availablerecruiting
NCT02727881
Efficacy and Safety Study of Squalamine Ophthalmic Solution in Subjects With Neovascular AMDtreatment3unknown_status
NCT01175395
20089 TA+Lucentis Combo Intravitreal Injections for Treatment of Neovascular Age-related Macular Degeneration (AMD)treatment1 / 2completed
NCT05135195
A Virtual Reality Platform Simulating Visual Impairment for Testing of Electronic Travel Aids and Performing Orientation and Mobility TrainingNo drug interventionsscreeningNot Availablecompleted
NCT00363714
A Dose Escalation Trial of an Intravitreal Injection of Sirna-027 in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)treatment1 / 2completed
NCT00607750
Safety and Efficacy of ATG003 in Patients With AMD Receiving Anti-VEGFtreatment2completed
NCT05675150
Expressive Arts-based Intervention for Adults With Age-related Visual ImpairmentNo drug interventionstreatmentNot Availablerecruiting
NCT01350323
Aqueous Vascular Endothelial Growth Factor (VEGF) Levels in Type 3 NeovascularizationNo drug interventionsNot AvailableNot Availablecompleted
NCT04032808
Evaluation of the Performance of Self-monitoring Optimized by Therapeutic Education in the Recurrence of Wet Age-related Macular Degeneration (AMD)No drug interventionsNot AvailableNot Availableunknown_status
NCT00487838
Effects of Sun Filters on Age-related Macular Degeneration in People With Lens ImplantsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03407274
Flavonoids and Age-related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted