Displaying drugs 551 - 575 of 2785 in total
| Name | Weight | Structure | Description | Categories |
|---|---|---|---|---|
| Elagolix | 631.6 C32H30F5N3O5 |  | A gonadotropin releasing hormone receptor antagonist used to treat moderate to severe pain in endometriosis. | Anti-Gonadotropin-Releasing Hormones |
| Glasdegib | 374.448 C21H22N6O |  | A sonic hedgehog receptor inhibitor used to treat newly diagnosed acute myeloid leukemia in patients over 75 years who cannot receive intense chemotherapy. | Hedgehog pathway inhibitors |
| Binimetinib | 441.233 C17H15BrF2N4O3 |  | A medication used to treat metastatic melanoma with specific mutations. | Mitogen-activated protein kinase (MEK) inhibitors / Protein Kinase Inhibitors |
| Dacomitinib | 469.939 C24H25ClFN5O2 |  | A medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution. | Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors / Protein Kinase Inhibitors |
| Duvelisib | 416.87 C22H17ClN6O |  | An inhibitor of phosphatidylinositol 3-kinase delta and gamma used to treat relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma. | Phosphatidylinositol-3-kinase (Pi3K) inhibitors |
| Lemborexant | 410.425 C22H20F2N4O2 |  | A dual orexin antagonist indicated for the treatment of sleep-onset and/or sleep maintenance insomnia. | Orexin Receptor Antagonists |
| Delafloxacin | 440.76 C18H12ClF3N4O4 |  | A fluoroquinolone antibiotic used to treat skin and skin structure infections. | Fluoroquinolones |
| Selinexor | 443.313 C17H11F6N7O |  | Selinexor is indicated in combination with bortezomib and dexamethasone for the treatment of multiple myeloma in adult patients who have received at least one prior therapy. Selinexor is also indicated... | Antineoplastic Agents / Antineoplastic and Immunomodulating Agents / Cytochrome P-450 CYP3A Substrates / Cytochrome P-450 CYP3A4 Substrates / Cytochrome P-450 Substrates / Nuclear Export Inhibitors / OATP1B3 inhibitors |
| Difelikefalin | 679.863 C36H53N7O6 |  | A kappa opioid receptor agonist used in the treatment of pruritus associated with chronic kidney disease in patients undergoing hemodialysis. | Kappa Opioid Receptor Agonist |
| Bempedoic acid | 344.492 C19H36O5 |  | A drug used in conjunction with lifestyle modification and/or other agents for the treatment of refractory hypercholesterolemia. | Adenosine Triphosphate-Citrate Lyase Inhibitor / Enzyme Inhibitors / Hypolipidemic Agents / Hypolipidemic Agents Indicated for Hyperlipidemia |
| Abametapir | 184.242 C12H12N2 |  | A pediculicide metalloproteinase used topically in the treatment of head lice infection. | Antiparasitic Products, Insecticides and Repellents / Cytochrome P-450 CYP1A2 Inhibitors / Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) / Cytochrome P-450 CYP1A2 Substrates / Cytochrome P-450 CYP2B6 Inhibitors / Cytochrome P-450 CYP2B6 Inhibitors (strength unknown) / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Inhibitors / Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) / Cytochrome P-450 Enzyme Inhibitors / Cytochrome P-450 Substrates / Ectoparasiticides, Incl. Scabicides / Ectoparasiticides, Incl. Scabicides, Insecticides and Repellents / Matrix Metalloproteinase Inhibitors / Pediculicides / Pyridines |
| Deflazacort | 441.524 C25H31NO6 |  | A corticosteroid used to treat Duchenne muscular dystrophy. | Glucocorticoids |
| Valbenazine | 418.578 C24H38N2O4 |  | A vesicular monoamine transporter 2 inhibitor used to treat tardive dyskinesia and chorea associated with Huntington's disease. | Vesicular Monoamine Transporter 2 Inhibitor |
| Apalutamide | 477.44 C21H15F4N5O2S |  | An androgen receptor inhibitor used to treat non-metastatic castration-resistant and metastatic castration-sensitive prostate cancer. | Antiandrogens |
| Infigratinib | 560.475 C26H31Cl2N7O3 |  | An FGFR inhibitor used to treat locally advanced or metastatic cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 (FGFR2) rearrangement. | Fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitors |
| Brexanolone | 318.4935 C21H34O2 |  | Brexanolone is a synthetic neuroactive steroid gamma-aminobutyric acid A (GABA(a)) receptor positive modulator indicated for the treatment of postpartum depression (PPD) in adult women [FDA Label][A176080, A176083, F4063, F4066, F4072]. | Anesthetics / Anticonvulsants / GABA Modulators / Neurotransmitter Agents |
| Revefenacin | 597.76 C35H43N5O4 |  | An anticholinergic agent used to treat COPD. | Anticholinergic Agents / Bronchodilator Agents / Muscarinic Antagonists |
| Relugolix | 623.64 C29H27F2N7O5S |  | An oral GnRH receptor antagonist for androgen deprivation therapy in the treatment of advanced prostate cancer. | Anti-Gonadotropin-Releasing Hormones |
| Osilodrostat | 227.242 C13H10FN3 |  | An oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism. | Anticorticosteroids |
| Indium In-111 pentetreotide | 1472.41 C62H80InN12O19S2 |  | Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome. | Indium (111In) Compounds |
| Neratinib | 557.05 C30H29ClN6O3 |  | A protein kinase inhibitor used to treat breast cancer that over expresses the HER2 receptor. | Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors / Protein Kinase Inhibitors |
| Ertugliflozin | 436.89 C22H25ClO7 |  | An SGLT2 inhibitor used to treat type 2 diabetes mellitus alone or in combination with other antidiabetic drugs. | Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors / Sodium-Glucose Transporter 2 Inhibitors |
| Esketamine | 237.73 C13H16ClNO |  | A NMDA receptor antagonist used for treatment-resistant depression. | Agents producing tachycardia / Anesthetics / Anesthetics, General / Antidepressive Agents / Antidepressive Agents Indicated for Depression / Central Nervous System Agents / Central Nervous System Depressants / Cyclohexanes / Cycloparaffins / Cytochrome P-450 CYP2B6 Inducers / Cytochrome P-450 CYP2B6 Inducers (weak) / Cytochrome P-450 CYP2B6 Substrates / Cytochrome P-450 CYP2C19 Substrates / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP3A Inducers / Cytochrome P-450 CYP3A Substrates / Cytochrome P-450 CYP3A4 Inducers / Cytochrome P-450 CYP3A4 Inducers (weak) / Cytochrome P-450 CYP3A4 Substrates / Cytochrome P-450 Enzyme Inducers / Cytochrome P-450 Substrates / Miscellaneous Antidepressants / Nervous System / NMDA Receptor Antagonists / Non-Competitive N-Methyl D-Aspartate (NMDA) Receptor Antagonists / Psychoanaleptics / Psychotropic Drugs |
| Nifurtimox | 287.29 C10H13N3O5S |  | An antiparasitic drug used for the treatment of Chagas disease (Trypanosoma cruzi infection). | Nitrofuran Derivatives |
| Baricitinib | 371.42 C16H17N7O2S |  | A Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist. | Selective Immunosuppressants |
Displaying drugs 551 - 575 of 2785 in total