Antidepressive Agents Indicated for Depression
- Name
- Antidepressive Agents Indicated for Depression
- Accession Number
- DBCAT005156
- Description
Included in this category are antidepressant agents that have been assigned indications for the treatment of depression, either alone or in combination with other agents. Excluded from this category are agents that may carry some antidepressant activity, but are not used clinically in the treatment of depression.
- Drugs
Drug Drug Description Amitriptyline A tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety. Amoxapine A tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression. Aripiprazole An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome. Brexpiprazole A serotonin–dopamine activity modulator used in the treatment of major depressive disorder as an adjunct, schizophrenia, and agitation associated with dementia due to Alzheimer’s disease. Bupropion A norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation. Citalopram A selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression. Clomipramine A tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder. Desipramine A tricyclic antidepressant used in the treatment of depression. Desvenlafaxine An antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. Doxepin A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia. Duloxetine A serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence. Escitalopram A selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD). Fluoxetine A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I. Fluvoxamine A selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder. Imipramine A tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis. Isocarboxazid A monoamine oxidase inhibitor used to treat enduring and debilitating symptoms of depression following inadequate clinical response to other antidepressant drugs. Levomilnacipran A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD) in adults. Maprotiline A tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression. Mirtazapine A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite. Moclobemide A monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder. Nefazodone An antidepressant used in the treatment of depression. Nortriptyline A tricyclic antidepressant used in the treatment of depression. Paroxetine A selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder. Phenelzine A monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression. Protriptyline A tricyclic antidepressant that is indicated in the treatment of depression only under close clinical supervision. Quetiapine An atypical antipsychotic agent used for the management of bipolar disorder, schizophrenia, and major depressive disorder. Selegiline A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's. Sertraline A selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. St. John's Wort An herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety. Tranylcypromine A monoamine oxidase inhibitor used to treat major depressive disorder. Trazodone A serotonin uptake inhibitor used to treat major depressive disorder. Trimipramine A tricyclic antidepressant used to treat depression. Venlafaxine A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression, generalized or social anxiety disorder, and panic disorder. Vilazodone An antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors. Vortioxetine A serotonin modulating antidepressant indicated for the treatment of major depressive disorder (MDD). Esketamine A NMDA receptor antagonist used for treatment-resistant depression. - Drugs & Drug Targets