Rifampicin | An antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis. |
Pioglitazone | A thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus. |
Cabazitaxel | An antineoplastic agent used for the treatment of hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen. |
Rilpivirine | A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). |
Dabrafenib | A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer. |
Idelalisib | An antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). |
Sacubitril | A neprilysin inhibitor used in combination with valsartan as an adjunct to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. |
Daclatasvir | A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. |
Velpatasvir | A NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis. |
Simeprevir | A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. |
Ginsenoside Rb1 | Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as... |
Ataluren | A medication used for the treatment of Duchenne muscular dystrophy. |
Voxilaprevir | A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. |
Enasidenib | An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation. |
Pibrentasvir | A Hepatitis C NS5A inhibitor used to treat Hepatitis C. |
Glecaprevir | A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. |
Rucaparib | An anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer. |
Baricitinib | A Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist. |
Levothyroxine | A synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. |
Paritaprevir | A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. |
Dipyridamole | A phosphodiesterase inhibitor used to prevent postoperative thromboembolic events. |
Atazanavir | An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. |
Vincristine | A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. |
Ivermectin | An anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis. |
Nefazodone | An antidepressant used in the treatment of depression. |
Nelfinavir | A viral protease inhibitor used in the treatment of HIV infection. |
Novobiocin | For the treatment of infections due to staphylococci and other susceptible organisms |
Nystatin | A polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species. |
Valspodar | Valspodar has been used in trials studying the treatment of Cancer, Sarcoma, Leukemia, Lymphoma, and Breast Cancer, among others. |
Silibinin | Currently being tested as a treatment of severe intoxications with hepatotoxic substances, such as death cap (Amanita phalloides) poisoning. |
Sulfasalazine | An anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis. |
Tipranavir | A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor. |
Cobicistat | A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection. |
Erythromycin | A macrolide antibiotic used to treat and prevent a variety of bacterial infections. |
Lopinavir | An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection. |
Telithromycin | An ketolide used to treat community acquired pneumonia of mild to moderate severity. |
Everolimus | A mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies. |
Asunaprevir | An NS3 protease inhibitor used to treat hepatitis C genotype 1b. |
Dovitinib | Investigated for use/treatment in multiple myeloma and solid tumors. |
Roxithromycin | Used to treat respiratory tract, urinary and soft tissue infections. |
Rifamycin | An antibacterial used to treat traveler's diarrhea. |
Cyclosporine | A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis. |
Cobimetinib | An antineoplastic agent and selective inhibitor of the mitogen-activated extracellular kinase (MEK) pathway used to treat unresectable or metastatic melanoma. |
Mifepristone | A cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation. |
Selinexor | Selinexor is indicated for the treatment of relapsed or refractory multiple myeloma in combination with dexamethasone.[label] Patients must have received at least 4 prior therapies and have disease which is... |
Beclomethasone dipropionate | An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks. |
Pexidartinib | An antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor. |
Fedratinib | Fedratinib is indicated to treat adults with primary or secondary myelofibrosis that is either intermediate-2 or high risk. |
Istradefylline | A selective adenoside A2A receptor antagonist indicated in adjunct to levodopa and carbidopa for the treatment of Parkinson's Disease. |
Gemfibrozil | A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia. |
Dronedarone | An antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation. |
Elexacaftor | A small molecule CFTR corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation. |
Ubrogepant | An oral CGRP antagonist used in the acute treatment of migraine with or without aura. |
Clarithromycin | A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection. |
Darolutamide | An androgen receptor antagonist used for castration-resistant, non-metastatic prostate cancer. |
Rimegepant | An oral CGRP receptor antagonist used for the acute treatment of migraines with or without aura in adults. |
Bempedoic acid | A drug used in conjunction with lifestyle modification and/or other agents for the treatment of refractory hypercholesterolemia. |
Ritonavir | An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. |
Remdesivir | A nucleoside analog used to treat RNA virus infections including COVID-19. |
Bortezomib | A proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies. |
Lurbinectedin | A chemotherapeutic DNA alkylating agent used in the treatment of metastatic small-cell lung cancer. |
Fostemsavir | An antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein. |
Pralsetinib | A RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer. |
Lonafarnib | A potent farnesyl transferase inhibitor used to reduce mortality associated with Hutchinson-Gilford progeria syndrome (HGPS) and other progeroid laminopathies. |
Tirbanibulin | A tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp. |
Lenvatinib | A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma. |