Prostatitis (DBCOND0005935)

Identifiers

Synonyms

Urethroprostatitis / Inflammatory disease of prostate, unspecified / Prostatitis (disorder) / Inflammatory diseases of prostate / Prostatitis, unspecified

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Flavoxate	A muscarinic antagonist and spasmolytic used for the symptomatic relief of conditions associated with lack of muscle control in the bladder, such as dysuria, urgency, and nocturia.	Muscarinic acetylcholine receptor M1target Muscarinic acetylcholine receptor M2target Muscarinic acetylcholine receptor M5target
Morniflumate	An NSAID derived from niflumic acid used in the symptomatic treatment of inflammatory conditions of the airways, ENT, and the urogenital and osteoarticular systems.	Polyunsaturated fatty acid 5-lipoxygenasetarget Prostaglandin G/H synthase 2target Polyunsaturated fatty acid 5-lipoxygenaseenzyme Prostaglandin G/H synthase 2enzyme Leukotriene B4 receptor 1target Thromboxane A2 receptortarget UDP-glucuronosyltransferase 1A9enzyme Prostaglandin G/H synthase 1target
Ofloxacin	An antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.	DNA gyrase subunit Atarget DNA topoisomerase 4 subunit Atarget DNA topoisomerase 2-alphatarget Cytochrome P450 1A2enzyme Organic cation/carnitine transporter 2transporter Multidrug resistance-associated protein 1transporter Solute carrier family 22 member 6transporter ATP-binding cassette sub-family C member 2transporter Solute carrier family 22 member 4transporter Bile salt export pumptransporter DNA gyrase subunit Atarget DNA gyrase subunit Btarget
Sulfamethizole	A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections.	Dihydropteroate synthasetarget Albumincarrier Cytochrome P450 2C9enzyme
Tetracycline	An antibiotic used to treat a wide variety of susceptible infections.	16S ribosomal RNAtarget Major prion proteintarget Albumincarrier Cytochrome P450 3A4enzyme Solute carrier family 22 member 6transporter Organic anion transporter 3transporter Solute carrier family 22 member 11transporter Solute carrier family 22 member 7transporter 30S ribosomal protein S3target 30S ribosomal protein S8target 30S ribosomal protein S19target 30S ribosomal protein S14target 30S ribosomal protein S7target Multidrug translocase MdfAtarget Protein-arginine deiminase type-4target Solute carrier organic anion transporter family member 2B1transporter

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT00236990	An Effectiveness and Safety Study of ELMIRON (Pentosan Polysulfate Sodium) for the Treatment of Chronic Non-Bacterial Inflammation of the Prostate Gland	Pentosan polysulfate	treatment	2	completed
NCT00103402	Trial to Compare Alfuzosin Versus Placebo in the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome	Alfuzosin	treatment	3	completed
NCT03720951	Applying Pulsed Radiofrequency to the Pudendal Nerve Bilaterally Vs Its Application to Sacral Nerve Roots S2,3 and 4 Bilaterally in Chronic Prostatitis	No drug interventions	treatment	Not Available	unknown_status
NCT02246361	Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication	No drug interventions	supportive_care	4	completed
NCT00701311	An Open-Label Study of CC-10004 for Chronic Prostatitis/Chronic Pelvic Pain Syndrome	Apremilast	treatment	2	completed
NCT00277511	Levofloxacin, Chronic Bacterial Prostatitis	Levofloxacin	treatment	3	completed
NCT00402688	An Effectiveness and Safety Study for Levofloxacin in Chronic Prostatitis	Levofloxacin	treatment	3	completed
NCT00169585	Levofloxacin For The Management Of Patients With Abnormal Prostate Specific Antigen (PSA)	Levofloxacin	other	3	completed
NCT00913315	Efficacy Study of Tamsulosin and Tolterodine Treatment for Chronic Prostatitis	Tamsulosin Tolterodine	treatment	Not Available	unknown_status
NCT00194636	Effectiveness of Sympathetic Plexus Block on Male Pelvic Pain (Prostatitis, Prostatodynia)	No drug interventions	treatment	4	suspended
NCT03879486	Infectious Outcomes of Povidone-iodine Rectal Cleansing Plus Formalin Disinfection of Needle During Prostate Biopsy	No drug interventions	prevention	Not Available	completed
NCT01676857	Chemokine Mechanisms in Chronic Pelvic Pain	No drug interventions	Not Available	Not Available	completed
NCT00464373	Botulinum Toxin Type A for the Treatment of Male Chronic Pelvic Pain Syndrome	Botulinum toxin type A	treatment	3	terminated
NCT03027076	Microbiome of Urologic Chronic Pelvic Pain Syndrome	No drug interventions	Not Available	Not Available	withdrawn
NCT00236808	A Study to Evaluate the Safety and Effectiveness of Levofloxacin Compared With Ciprofloxacin in Patients With Chronic Bacterial Prostatitis	Levofloxacin	treatment	3	completed
NCT03931538	Rapid Molecular Organism Identification and Mixed Flora Antibiotic Resistance Profiling (MixAR) Prospective Study	No drug interventions	diagnostic	Not Available	completed
NCT01886547	2013 Annual National Digital Rectal Exam (DRE) Day Study	No drug interventions	Not Available	Not Available	completed
NCT01932645	Etiology Study of Prostatitis	No drug interventions	Not Available	Not Available	unknown_status
NCT00675298	Linkage Analysis in Interstitial Cystitis	No drug interventions	Not Available	Not Available	completed
NCT00194597	Trial of Viagra' in Men With Chronic Pelvic Pain Syndrome Type III	Sildenafil	treatment	4	terminated
NCT01678911	Efficacy of Gralise® for Chronic Pelvic Pain	Gabapentin	treatment	4	terminated
NCT00775515	Laparoscopic Prostatectomy for Chronic Prostatitis	No drug interventions	treatment	2	unknown_status
NCT00260637	Efficacy Study of Acupuncture to Relieve Symptoms of Chronic Prostatitis	No drug interventions	treatment	2 / 3	completed
NCT05732441	Therapeutic Study of Prostatitis With Elevated PSA	No drug interventions	treatment	Not Available	active_not_recruiting
NCT01826617	Configuration of a New Prostate Disease Nomogram Predicting Prostate Biopsy Outcome	No drug interventions	Not Available	Not Available	completed
NCT00529386	Botox for Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)	Botulinum toxin type A	treatment	1	terminated
NCT05306314	Retrospective Chart Review of Treataprost Added to Antibiotic Treatment in Patients With Chronic Prostatitis	No drug interventions	Not Available	Not Available	unknown_status