superficial ocular infections (DBCOND0020669)

Identifiers

Synonyms

Superficial Eye Infections / Superficial Eye infection / Superficial ocular infection

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Betamethasone	A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.	Glucocorticoid receptortarget Cytochrome P450 3A4enzyme ATP-dependent translocase ABCB1transporter Aromataseenzyme Cytochrome P450 3A5enzyme Cytochrome P450 3A7enzyme Cytochrome P450 2A6enzyme Cytochrome P450 1B1enzyme Cytochrome P450 2B6enzyme Cytochrome P450 2C8enzyme Cytochrome P450 2C9enzyme Cytochrome P450 2C19enzyme Albumincarrier Corticosteroid-binding globulincarrier
Chloramphenicol	A broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity.	Complement decay-accelerating factortarget Dr hemagglutinin structural subunittarget Cytochrome P450 2C19enzyme Cytochrome P450 3A4enzyme Cytochrome P450 3A5enzyme Cytochrome P450 3A7enzyme Solute carrier family 22 member 6transporter 50S ribosomal protein L16target Chloramphenicol acetyltransferase 3enzyme Chloramphenicol acetyltransferaseenzyme Chloramphenicol 3-O phosphotransferaseenzyme
Erythromycin	A macrolide antibiotic used to treat and prevent a variety of bacterial infections.	23S ribosomal RNAtarget Cytochrome P450 3A4enzyme Cytochrome P450 3A7enzyme ATP-dependent translocase ABCB1transporter Solute carrier organic anion transporter family member 1B1transporter Motilin receptortarget Voltage-gated inwardly rectifying potassium channel KCNH2target Cytochrome P450 3A5enzyme Solute carrier organic anion transporter family member 1B3transporter Bile salt export pumptransporter ATP-binding cassette sub-family C member 2transporter Solute carrier organic anion transporter family member 1A2transporter
Gramicidin D	A bactericidal antibiotic used in the treatment of dermatological and ophthalmic infections.	ATP-dependent translocase ABCB1transporter Dihydropteroate synthasetarget
Oxytetracycline	A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.	30S ribosomal protein S4target 30S ribosomal protein S9target 16S ribosomal RNAtarget Solute carrier family 22 member 6transporter Organic anion transporter 3transporter Solute carrier family 22 member 11transporter Solute carrier family 22 member 7transporter Albumincarrier
Prednisolone acetate	A glucocorticoid used to treat a wide variety of endocrine, inflammatory, and immune conditions as well as for palliation of neoplastic conditions.	Corticosteroid-binding globulincarrier Cytochrome P450 3A4enzyme Glucocorticoid receptortarget Solute carrier organic anion transporter family member 1A2transporter ATP-dependent translocase ABCB1transporter Albumincarrier
Sulfacetamide	A sulfonamide used to treat inflammatory ocular conditions and acne vulgaris.	Dihydropteroate synthasetarget Dihydropteroate synthase type-1target Folic acid synthesis protein FOL1target

Clinical Trials

Not Available