Endometrial Carcinoma (DBCOND0031833)

Identifiers

Synonyms
Endometrial Carcinoma (EC) / Carcinoma of the Endometrium / Carcinoma of Endometrium / Uterine Endometrial Carcinoma / Endometrial carcinoma / Endometrial carcinoma (disorder) / Carcinoma endometrial / Endometrial cancer NOS / Cancer of endometrium / Endometrial cancer / Primary malignant neoplasm of endometrium (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Lenvatinib
A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
Lynestrenol
A progestin used for contraception and in the treatment of menstrual disorders.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06129604
Pilot Window of Opportunity Trial (POET)No drug interventionstreatment2recruiting
NCT02115477
Lymphedema After Primary Surgery for Endometrial CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT04080284
Trial of Maintenance With Niraparib- Uterine Serous CarcinomaNo drug interventionstreatment2recruiting
NCT02983279
Caloric Restriction Before Surgery in Treating Patients With Endometrial, Prostate, or Breast CancerNo drug interventionstreatmentNot Availablecompleted
NCT03902379
Web-Based Coping and Communication Skills Intervention in Improving Psychological Adaptation in Patients With Gynecological CancerNo drug interventionssupportive_careNot Availablewithdrawn
NCT00423254
Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.No drug interventionstreatment1completed
NCT01184053
Trisenox® in Women With Metastatic Endometrial Cancertreatment2terminated
NCT02017353
Effect of Curcumin Addition to Standard Treatment on Tumour-induced Inflammation in Endometrial CarcinomaNo drug interventionstreatment2completed
NCT00756847
Safety Study of XL147 (SAR245408), in Combination With Paclitaxel and Carboplatin in Adults With Solid Tumorstreatment1completed
NCT04257045
Factors Influencing Cascade Testing Among Women With Hereditary Gynecological Cancers and Their RelativesNo drug interventionsNot AvailableNot Availablecompleted
NCT03241745
A Study of Nivolumab in Selected Uterine Cancer Patientstreatment2completed
NCT06365905
Non-Invasive Identification of Endometrial Cancer/Endometrial Atypical Hyperplasia With an AI-Based Classifier Applied to Transvaginal Ultrasound in Patients With Post-Menopausal BleedingNo drug interventionsNot AvailableNot Availablerecruiting
NCT03671811
Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomytreatment2active_not_recruiting
NCT02584478
Phase 1/2a/3 Evaluation of Adding AL3818 to Standard Platinum-Based Chemotherapy in Subjects With Recurrent or Metastatic Endometrial, Ovarian, Fallopian, Primary Peritoneal or Cervical Carcinoma (AL3818-US-002)treatment3active_not_recruiting
NCT02025985
Study of KPT-330 (Selinexor) in Female Patients With Advanced Gynaecologic Malignanciestreatment2completed
NCT04830332
Correlation of Peritoneal Fluid CA-125 Levels With Postoperative Tumor HistologyNo drug interventionsdiagnosticNot Availablecompleted
NCT04152499
Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapiestreatment1 / 2recruiting
NCT01273636
Risk Factors for Concurrent Endometrial Carcinoma in Patients With a Curettage Diagnosis of Endometrial HyperplasiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04851119
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumorstreatment1 / 2recruiting
NCT02646319
Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutationstreatment0completed
NCT02465541
Gentle Yoga and Dietary Counseling in Improving Physical Function and Quality of Life in Stage I-II Endometrial Cancer SurvivorsNo drug interventionssupportive_careNot Availablecompleted
NCT05712941
Comparison of Letrozole With Lerociclib Versus Letrozole With Placebo Control in Patients With Advanced/Metastatic or Recurrent, Grade 1 or Grade 2 Endometrial Cancertreatment3withdrawn
NCT02611024
Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumorstreatment1 / 2recruiting
NCT02506816
Preoperative Olaparib Endometrial Carcinoma Study (POLEN)Not AvailableNot Availablecompleted
NCT04251416
A Study of Sacituzumab Govitecan (IMMU-132) in Endometrial Carcinomatreatment2recruiting
NCT00791635
Longitudinal Evaluation of Women Undergoing Pelvic Surgery for the Treatment of Gynecologic CancerNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05121363
A Clinical Trial to Evaluate TQB2858 Injection Combined With Anlotinib Hydrochloride Capsule in the Treatment of Recurrent or Metastatic Advanced Endometrial Carcinomatreatment2unknown_status
NCT00729586
Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial Cancertreatment2completed
NCT04716686
Niraparib Monotherapy as Maintain and Recurrent Treatment of Endometrial Serous Carcinomatreatment2recruiting
NCT03945786
Diagnostic Performance of Hybrid PET/MRI in the Staging of Endometrial CarcinomaNo drug interventionsNot AvailableNot Availablesuspended
NCT03372720
Fractional CO2 Laser Therapy in Minimizing Genitourinary Syndrome of Menopause in Gynecological Cancer SurvivorsNo drug interventionssupportive_careNot Availablecompleted
NCT00997373
Letrozole as a Treatment of Endometrial CancertreatmentNot Availablecompleted
NCT03877627
The Clinical Significance of Sentinel Lymph Node Imaging Combined With Imaging Examination in Pelvic and Peritoneal Lymphadenectomy for Endometrial CarcinomaNo drug interventionstreatmentNot Availableunknown_status
NCT02465060
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)screening2active_not_recruiting
NCT06253494
Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancertreatment1 / 2recruiting
NCT03015129
A Study of Durvalumab With or Without Tremelimumab in Endometrial Cancertreatment2completed
NCT05086692
A Beta-only IL-2 ImmunoTherapY StudyNo drug interventionstreatment1 / 2recruiting
NCT06413992
Camrelizumab Plus Fluzoparib for TP-53 Mutated Endometrial CancerNo drug interventionstreatment2recruiting
NCT02807844
Phase Ib/II Study of MCS110 in Combination With PDR001 in Patients With Advanced MalignanciesNo drug interventionstreatment1 / 2completed
NCT01366144
Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney DysfunctionNo drug interventionstreatment1active_not_recruiting
NCT05059444
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy EvaluationNo drug interventionsNot AvailableNot Availablerecruiting
NCT02628067
Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)No drug interventionstreatment2recruiting
NCT04224467
The Application of Real-Time Near-infrared Imaging in Gynecological SurgeryNo drug interventionsdiagnosticNot Availablerecruiting
NCT03076372
A Study Evaluating MM-310 in Patients With Solid TumorsNo drug interventionstreatment1unknown_status
NCT03917381
GEN1046 Safety Trial in Patients With Malignant Solid TumorsNo drug interventionstreatment1 / 2active_not_recruiting
NCT05036681
A Phase II Study of Futibatinib and Pembrolizumab in Metastatic Microsatellite Stable Endometrial CarcinomaNo drug interventionstreatment2recruiting
NCT00334295
Fulvestrant for the Treatment of Recurrent or Metastatic Endometrial Carcinoma.No drug interventionstreatment2completed
NCT02730923
Hormone Receptor Positive endometrIal Carcinoma Treated by Dual mTORC1/mTORC2 Inhibitor and Anastrozole (VICTORIA)No drug interventionstreatment1 / 2active_not_recruiting
NCT06502743
First-line Carboplatin and Paclitaxel in Combination With Pembrolizumab, Followed by Maintenance Pembrolizumab With or Without Nesuparib, in Patients With Newly Diagnosed Advanced or Recurrent MMR-proficient (pMMR) Endometrial CancerNo drug interventionstreatment2not_yet_recruiting
NCT05950464
Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial CancerNo drug interventionstreatment1recruiting
NCT04474184
Development of a New Early Detection Test to Reduce Racial Disparities in Endometrial Cancer (EC) Death RatesNo drug interventionsscreening1completed
NCT03027479
Skeletal Muscle Energy Metabolism in Women With Weight Loss and Ovarian and/or Endometrial Cancer With Weight LossNo drug interventionshealth_services_researchNot Availablecompleted
NCT05714553
NUC-3373 in Combination With Other Agents in Patients With Advanced Solid TumoursNo drug interventionstreatment1 / 2recruiting
NCT03752398
A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3)No drug interventionstreatment1completed
NCT03460483
Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized CareNo drug interventionsscreeningNot Availableactive_not_recruiting
NCT01455493
A Study of GDC-0980 in the Treatment of Recurrent or Persistent Endometrial CarcinomaNo drug interventionstreatment2completed
NCT04567771
Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical CancerNo drug interventionstreatmentNot Availablerecruiting
NCT03517488
A Study of XmAb®20717 in Subjects With Selected Advanced Solid TumorsNo drug interventionstreatment1completed
NCT05894915
Study and Transformation of Tumor Molecular Features Screening Model of Endometrial Carcinoma Surgical ApproachNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06102252
Combination Chemotherapy of Paclitaxel and Carboplatin With or Without Anthracycline as Aneo Adjuvant Treatment in Advanced Endometrial CarcinomaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00879359
Trial of Vascular Endothelial Growth Factor (VEGF), Bevacizumab, in Combination With Cytotoxic Chemotherapy for Endometrial CancerNo drug interventionstreatment2completed
NCT04713618
Changes in Pelvic Health, Sexual Function, and Quality of Life in Women With Pelvic Cancer Undergoing Radiation TherapyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02598219
Evaluation of Sentinel Node Policy in Early Stage Endometrial Carcinomas at Intermediate and High Risk of Recurrence.No drug interventionstreatment3active_not_recruiting
NCT04634617
Pelvic Floor Dysfunction and Quality of Life in Uterine Cancer SurvivorsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05407025
Targeting Inflammation for Endometrial Cancer PreventionNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05669430
A Study of GV20-0251 in Patients With Solid Tumor MalignanciesNo drug interventionstreatment1recruiting
NCT00165126
Dosimetric Analysis of Vaginal Cuff Brachytherapy in Endometrial CarcinomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00483327
Management of Atypical Endometrial Hyperplasia and Endometrial Carcinoma Using Megestrol AcetateNo drug interventionstreatment2completed
NCT04652076
GYNecological Cancers Treated With NETrin mAbs in Combination With Chemotherapy and /or PembrolizumabNo drug interventionstreatment1 / 2recruiting
NCT04178460
A Study of Niraparib Combined With MGD013 in Patients With Advanced or Metastatic Solid Tumor Who Failed Prior TreatmentNo drug interventionstreatment1terminated
NCT05316467
Weight Management Plus Megestrol Acetate in Early-stage Endometrioid CarcinomaNo drug interventionstreatment2 / 3recruiting
NCT02368067
Improved Method of Detecting Cancer MetastasesNo drug interventionstreatmentNot Availableunknown_status
NCT04576104
Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial CancerNo drug interventionsprevention2recruiting
NCT05139368
Hypofractionated Radiotherapy for the Treatment of Cervical or Endometrial CancerNo drug interventionstreatmentNot Availablerecruiting
NCT03849469
A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid TumorsNo drug interventionstreatment1completed
NCT05691010
A Study of Short-Course Radiation Therapy With Chemotherapy in People With Endometrial CancerNo drug interventionstreatment0recruiting
NCT02977195
First in Human Evaluation of Safety, Pharmacokinetics, and Clinical Activity of a Monoclonal Antibody Targeting Netrin 1 in Patients With Advanced/Metastatic Solid TumorsNo drug interventionstreatment1completed
NCT04839614
Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial NeoplasiaNo drug interventionshealth_services_researchNot Availablerecruiting
NCT04678414
Infertility Survey Among Reproductive Age Women With Gynecological and Breast CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT04159155
A Study of Various Treatments in Serous or p53 Abnormal Endometrial CancerNo drug interventionstreatment2 / 3recruiting
NCT03745950
UTOLA: UTerin OLAparibNo drug interventionstreatment2active_not_recruiting
NCT02630823
MK-3475 Immunotherapy in Endometrial CarcinomaNo drug interventionstreatment1completed
NCT03367923
Health and Recovery Program in Increasing Physical Activity Level in Stage IA-IIIA Endometrial Cancer SurvivorsNo drug interventionssupportive_care2completed
NCT02387645
LUDEC Study - Pilot Study of the Lavage of the Uterine Cavity for the Diagnosis of Endometrial CarcinomaNo drug interventionsdiagnosticNot Availablecompleted