Coronary Artery Atherosclerosis (DBCOND0051452)

Identifiers

Synonyms
Arteriosclerosis coronary artery / Atherosclerosis, Coronary / Coronary Atherosclerosis / Coronary artery atherosclerosis / Atherosclerotic heart disease of native coronary artery without angina pectoris / Atherosclerotic heart disease of native coronary artery / Chronic passive congestion of liver / Coronary artery sclerosis / Coronary sclerosis / Arteriosclerotic heart disease / Atherosclerosis of coronary artery (disorder) / Coronary arteriosclerosis (disorder) / Coronary Arteriosclerosis

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Atenolol
A synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients.
Lovastatin
An HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke.
Pravastatin
An HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke.
Propranolol
A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04010955
Adding Antiplatelet During Edoxaban Treatment in Stroke Patients With Non-valvular Atrial Fibrillation (ADD-ON)Not AvailableNot Availableunknown_status
NCT01310608
Effect Study of Modified Transoesophageal Echocardiography on Cerebral Embolization After Cardiothoracic SurgeryNo drug interventionsdiagnostic3completed
NCT04810364
HIV Infection And Evolvement of Atherosclerotic PlaqueNo drug interventionsNot AvailableNot Availableunknown_status
NCT05492084
Personalized Risk of Rapidly Progressive AtherosclerosisNo drug interventionsNot AvailableNot Availablecompleted
NCT00146887
Comparison of Coronary CT Angiography to Invasive Coronary AngiographyNo drug interventionsdiagnosticNot Availableunknown_status
NCT03471611
Study of Intracoronary CD34+ Cell Administration in Patients With Early Coronary Atherosclerosistreatment1completed
NCT01234870
Comprehensive Evaluation of Ischemic Heart Disease Using MRIdiagnostic2 / 3completed
NCT03149042
Validation of a Computed Tomography (CT) Based Fractional Flow Reserve (FFR) Software Using the 320 Detector Aquilion ONE CT Scanner.No drug interventionsNot AvailableNot Availablecompleted
NCT03174418
Fluid-dynamics in Bifurcation PCINo drug interventionsNot AvailableNot Availableunknown_status
NCT03813017
Comprehensive Assessment of Subclinical Atherosclerosis in Patients With Rheumatoid ArthritisNo drug interventionsNot AvailableNot Availableunknown_status
NCT03427996
Evaluation of Effectiveness and Safety of Rotational Atherectomy in Routine Clinical PracticeNo drug interventionsNot AvailableNot Availablerecruiting
NCT06393894
Latvian Early Atherosclerosis RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT02389946
Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery LesionsNo drug interventionstreatmentNot Availablecompleted
NCT03129503
Optical Coherence Tomography in Acute Coronary SyndromeNo drug interventionsNot AvailableNot Availableunknown_status
NCT00115583
The Contribution of Endothelin to Vasomotor Function in Diseased Coronary ArteriesNot AvailableNot Availablecompleted
NCT04853511
Comprehensive Assessment of Interconnection Between Brain Emotional Activity and Coronary Plaque InstabilityNo drug interventionsNot AvailableNot Availablerecruiting
NCT05600088
Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With NSTEMI or Unstable AnginaNo drug interventionsdevice_feasibilityNot Availablerecruiting
NCT03815032
Assessing the Accuracy of the OptoWire DeuxTM in a Wire to Wire ComparisonNo drug interventionsdiagnosticNot Availablecompleted
NCT03011775
Effect of Pioglitazone on Insulin Resistance, Atherosclerosis Progression and Clinical Course of Coronary Heart Diseaseprevention4completed
NCT04175626
Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery LesionsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04762472
Air Pollution (PM2.5) on Accelerated Atherosclerosis: A Montelukast Interventional Study in Modernizing Chinaprevention4not_yet_recruiting
NCT00353795
Coronary Atherosclerosis Evaluation by Arterial Wall Magnetic Resonance Imaging (MRI)No drug interventionsdiagnosticNot Availablecompleted
NCT05540223
Safety and Clinical Performance of the DREAMS 3G Resorbable Magnesium Scaffold SystemNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00790764
Phase II Combination Stem Cell Therapy for the Treatment of Severe Coronary Ischemia(CI)No drug interventionstreatment2suspended
NCT02076802
Regular Physical Exercise and Salt Diet on Coronary Artery Disease in Patients With Prehypertension(RESTRAIN Pre-HT)No drug interventionsNot AvailableNot Availableunknown_status
NCT00358033
Strategies to Maintain Cardiac Risk Control After Discharge From Cardiovascular Risk Reduction ClinicNo drug interventionstreatment3completed
NCT00606333
Comparison of the Conor Sirolimus-eluting Coronary Stent to the Taxus Liberte Paclitaxel-eluting Coronary Stent in the Treatment of Coronary Artery LesionsNo drug interventionstreatmentNot Availableterminated
NCT03230851
the Efficacy and Safety of Indobufen and Low-dose Aspirin in Different Regimens of Antiplatelet Therapytreatment4unknown_status
NCT02305953
Cytokines and Vascular Inflammation in PsoriasisNo drug interventionsNot AvailableNot Availablecompleted
NCT05708547
Role of Mitophagy in Myeloid Cells During Coronary Atherosclerosis.No drug interventionsNot AvailableNot Availablerecruiting
NCT05660798
Effects of Switching From Cigarettes to Tobacco Heating System on Coronary Atherosclerosis ProgressionNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT00455793
Subclinical Atherosclerosis in HIV-infected PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01557088
Lp-PLA2 and Coronary Atherosclerosis in HumansNo drug interventionsdiagnosticNot Availablecompleted
NCT00570609
CPR Training in 7th Grade StudentsNo drug interventionspreventionNot Availablecompleted
NCT01416532
Evaluation of Subclinical COronary Atherosclerosis for Risk Stratification Using Coronary Computed Tomography (CT) AngiographyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01254552
Assessment With CCTA and MRI in Asymptomatic Patients With Type 2 Diabetes for Detection of Unrecognized Myocardial Scar in Subclinical Coronary Atherosclerosisdiagnostic4completed
NCT03087175
MGuard Stent and MicrocirculationNo drug interventionstreatmentNot Availablecompleted
NCT00376870
PIoglitazone for PrEvention of Restenosis in Diabetic Patientstreatment3unknown_status
NCT01182649
Everolimus Stent in Patients With Coronary Artery Disease (CAD)No drug interventionstreatment3completed
NCT01268319
CANARY: Coronary Assessment by Near-infrared of Atherosclerotic Rupture-prone YellowNo drug interventionstreatmentNot Availableterminated
NCT00431717
Coronary Computed Tomography Angiography and SPECT in Asymptomatic DiabetesNo drug interventionsNot AvailableNot Availablecompleted
NCT03401216
StEnt Coverage and Neointimal Tissue Characterization After eXtra Long evErolimus - Eluting Stent imPlantationNo drug interventionstreatmentNot Availableunknown_status
NCT00544739
Premature Coronary Artery Disease in Women - Risk Factors and PrognosisNo drug interventionsNot AvailableNot Availablecompleted
NCT01699230
Potential Effects of Omega 3 Supplementation on Cardiomyocytes Membranes for Patients With Coronary Atherosclerosis?No drug interventionsNot Available3unknown_status
NCT00123565
Hexadecasaccharide (SR123781A) in Patients With Unstable Angina or Non-ST-Segment Elevation Myocardial Infarctiontreatment2completed
NCT02208765
Prognostic Value of SPECT-imaging Myocardial Perfusion HeterogeneityNo drug interventionsdiagnosticNot Availableunknown_status
NCT02316782
Bifurcation Lesion Analysis and STenting / BLASTNo drug interventionsNot AvailableNot Availablecompleted
NCT01642173
Assessment of Coronary Plaque Composition Using Optical Coherence TomographyNo drug interventionsbasic_science1completed
NCT00853827
Safety and Efficacy of Aliskiren on the Progression of Atherosclerosis in Coronary Artery Disease Patientstreatment3completed
NCT04559191
Atheroma Progression and Vulnerability Under Continuous Glucose MonitoringNo drug interventionstreatment4unknown_status
NCT02708329
T-provisional Stenting vs Mini-Crush in Chronic Total Occlusions (CTO)No drug interventionstreatmentNot Availablecompleted
NCT02576704
Prognostic Value of Myocardial Perfusion Heterogeneity in Normal SPECT StudiesNo drug interventionsNot AvailableNot Availablecompleted
NCT00811772
Trial of Drug Eluting Stent Versus Bare Metal Stent to Treat Coronary Artery StenosisNo drug interventionstreatmentNot Availablecompleted
NCT02440646
Natural History of Coronary Atherosclerosis in Real-World Stable Chest Pain Patients Underwent Computed Tomography Angiography in Comparison With Invasive Multimodality ImagingNo drug interventionsNot AvailableNot Availableterminated
NCT02265146
ORACLE-NIRS: Lipid cORe Plaque Association With CLinical Events: a Near-InfraRed Spectroscopy StudyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00643981
Combination Stem Cell Therapy for the Treatment of Severe Coronary IschemiaNo drug interventionstreatment1completed
NCT05105750
A Comparative Study of Indobufen and Aspirin in Patients With Coronary Atherosclerosistreatment4unknown_status
NCT02769650
Stress-MRI Assessment After Right Coronary Artery CTO RecanalizationNo drug interventionsdiagnosticNot Availablecompleted
NCT00243308
Serp-1 for the Treatment of Acute Coronary Syndromediagnostic2terminated
NCT00715884
Study Comparing the CYPHER® ELITE™ to the CYPHER® Bx VELOCITY® Sirolimus-Eluting Stent SystemsNo drug interventionstreatmentNot Availableunknown_status
NCT02313987
Endothelial Function-guided Therapy Compared to Usual Care in Patients With NOCADNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00552877
The SOURT OUT IV TRIALNo drug interventionstreatmentNot Availablecompleted
NCT00431977
Validation Study of Coronary CT Angiography as a Screening Tool in Asymptomatic DiabetesNo drug interventionsscreeningNot Availablecompleted
NCT00860847
Firefighter Aged Garlic Extract Investigation With CoQ10 as a Treatment for Heart Disease (FAITH)No drug interventionsprevention3completed
NCT01061398
CT-FIRST: Cardiac Computed Tomography Versus Stress Imaging For Initial Risk STratificationNo drug interventionsdiagnosticNot Availableunknown_status
NCT02000661
Routine Versus Selective Use of FFR to Guide PCINo drug interventionstreatment4terminated
NCT01030328
AFRICA: Atorvastatin Plus Fenofibric Acid (TriLipix) in the Reduction of Intermediate Coronary Atherosclerosisdiagnostic3terminated
NCT02926807
Trial on Vascular Inflammation in Atopic DermatitisNo drug interventionsNot AvailableNot Availablecompleted
NCT02360956
Efficacy Study of Olmesartan Medoxomil on Coronary Atherosclerosis and Epicardial Adipose Tissue(EAT)treatment4unknown_status
NCT03504956
Coronary Atherosclerosis T1-Weighted Characterization (CATCH)otherNot Availablerecruiting
NCT03322332
Adipokines of Epicardial Adipose Tissue and Atherosclerosis of Coronary ArteriesNo drug interventionsNot AvailableNot Availableunknown_status
NCT00124332
STRADIVARIUS (Strategy To Reduce Atherosclerosis Development InVolving Administration of Rimonabant - the Intravascular Ultrasound Study)treatment3completed
NCT01581632
Assessment of Coronary Plaque CompositionNo drug interventionsbasic_science1completed
NCT01316159
Prediction of Progression of Coronary Artery Disease (CAD) Using Vascular Profiling of Shear Stress and Wall MorphologyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00620542
CRESTOR Athero Imaging Head to Head IVUS Studytreatment3completed
NCT00548613
Combination Stem Cell (MESENDO) Therapy for Utilization and Rescue of Infarcted MyocardiumNo drug interventionstreatment1completed
NCT02681016
Sirolimus-eluting Stent CALYPSO vs Everolimus-eluting Stent XIENCENo drug interventionstreatmentNot Availablecompleted
NCT02335086
DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01853527
Myocardial Ischemia in Non-obstructive Coronary Artery DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00431860
Subclinical COronary Atheroscleorosis Updated With Coronary cT Angiography (SCOUT Study)No drug interventionsNot AvailableNot Availableunknown_status
NCT00940862
Effect of Adalimumab on Vascular Inflammation in Patients With Moderate to Severe Plaque Psoriasisprevention4completed
NCT00294567
Azelnidipine Anti-Coronary Atherosclerotic Trial in Hypertensive Patients by Serial Volumetric IVUS Analysis(ALPS-J)prevention4completed
NCT02151812
Comparison of Agent™ and SeQuent® Please Paclitaxel Coated Balloon Catheters in Coronary In-stent Restenosis (AGENT-ISR)No drug interventionstreatmentNot Availablecompleted
NCT01722214
Trial on the Effect of Adalimumab on Vascular Inflammation in Patients With Psoriasisprevention4completed
NCT00155350
Treatment of Coronary Atherosclerosis by Insulin Sensitizers in Insulin-Resistant Patientstreatment4unknown_status