Hypermenorrhea (DBCOND0052994)

Identifiers

Synonyms
Menorrhagia / Excessive and frequent menstruation with regular cycle / Heavy menstrual bleeding / Menorrhagia (finding) / Menstrual flow excessive / Hypermenorrhoea / Heavy periods / Excessive menstruation / Bleeding menstrual heavy / Menses regular with excessive bleeding / Prolonged heavy periods / Menstruation increased

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Dienogest
An oral progestin used for the treatment of endometriosis as monotherapy or contraception in combination with ethinylestradiol.
Ethynodiol diacetate
An oral contraceptive used to prevent pregnancy.
Levonorgestrel
A progestin found in oral and IUD contraceptives and at higher doses in emergency contraceptives.
Lynestrenol
A progestin used for contraception and in the treatment of menstrual disorders.
Meclofenamic acid
An NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
Mestranol
A synthetic estradiol found in oral contraceptive pills for contraception and the treatment of other conditions in the female reproductive system, such as dysmenorrhea and dysfunctional uterine bleeding.
Norgestimate
A progesterone used as a contraceptive and to treat acne vulgaris.
Norgestrel
A progestin used in combination with ethinyl estradiol for oral contraception and prevention of pregnancy in women.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01391052
Pretreatment With Norethindrone Acetate Prior to Levonorgestrel IUS Insertion for Heavy Menstrual Bleedingtreatment4unknown_status
NCT01226290
Fibroid Ablation StudyNo drug interventionstreatmentNot Availableterminated
NCT00360490
Study in Women With Idiopathic Menorrhagia to Determine the Reduction in Menstrual Blood Loss (MBL) After Treatment With the Levonorgestrel-releasing Intrauterine System (IUS)No drug interventionstreatment3completed
NCT00966264
Hysterectomy and Levonorgestrel Releasing Intrauterine System (LNG-IUS) in the Treatment of MenorrhagiaNo drug interventionstreatment3completed
NCT01793584
Surgical Success After Laparoscopic vs Abdominal HysterectomyNo drug interventionshealth_services_researchNot Availablecompleted
NCT01460043
Trial of Homeopathy on Management of MenorrhagiaNo drug interventionstreatmentNot Availablecompleted
NCT01965587
RCT Novasure Versus Novasure + Mirena IUS in the Treatment of MenorrhagiaNo drug interventionspreventionNot Availableunknown_status
NCT01740687
A Study to Evaluate the Effectiveness of Essure Post-NovaSure Radiofrequency Endometrial Ablation Procedure Following a Successful Essure Confirmation TestNo drug interventionsNot AvailableNot Availablecompleted
NCT00874653
Survey on Patient Satisfaction Rate for Mirena Use in Heavy Menstrual BleedingNot AvailableNot Availablecompleted
NCT01848847
Relationship Between Bladder Distention and Hysteroscopy ApplicationNo drug interventionsdiagnosticNot Availablecompleted
NCT00393198
Bleeding Pattern and User Satisfaction During Second Consecutive MIRENA® in Contraception and Treatment of MenorrhagiaNo drug interventionstreatment4completed
NCT01581905
Study of Conventional Laparoscopic Hysterectomy Versus Robot-Assisted Laparoscopic Hysterectomy at a Teaching InstitutionNo drug interventionstreatmentNot Availableterminated
NCT02087228
Evaluation of the Endometrial Cavity After Endometrial AblationNo drug interventionstreatmentNot Availableterminated
NCT00354471
Uterine Artery Embolization for Symptomatic FibroidsNo drug interventionsNot AvailableNot Availablecompleted
NCT00114088
Surgical Treatments Outcomes Project for Dysfunctional Uterine Bleeding (STOP-DUB)No drug interventionstreatment3completed
NCT02584088
Ultrasound Appearance of the Endometrium Post Radio-Frequency AblationNo drug interventionsNot AvailableNot Availablecompleted
NCT01165307
Medical Therapy Versus Radiofrequency Endometrial Ablation in the Initial Treatment of Menorrhagiatreatment4completed
NCT00152256
A Study to Evaluate of the Safety and Effectiveness of Asoprisnil in Treating Women With Uterine Fibroidstreatment3completed
NCT00111215
Treatment and Management of Women With Bleeding DisorderspreventionNot Availablecompleted
NCT00556400
Treatment of Menorrhagia in Women With Thrombocytopenia Using Platelets or Platelets and HormonesNo drug interventionstreatment1 / 2terminated
NCT01266759
Efficacy of Combined Contraceptive Vaginal Ring(NuvaRing)in Women With Idiopathic MenorrhagiatreatmentNot Availablecompleted
NCT00323999
Hysteroscopic Monopolar and Bipolar ResectionNo drug interventionsNot AvailableNot Availableunknown_status
NCT03725306
Librata Endometrial Ablation Device Treatment to Reduce Menstrual Blood LossNo drug interventionstreatment3unknown_status
NCT02842736
A CLinical Study to Evaluate the Safety And Effectiveness of the CeRene DevIce to Treat HeavY Menstrual BleedingNo drug interventionstreatmentNot Availablecompleted
NCT00864136
Mirena or Conventional Medical Treatment for MenorrhagiaNot AvailableNot Availablecompleted
NCT00215618
Uterine Balloon Treatment for Heavy Period Bleeding.No drug interventionstreatment3completed
NCT00731341
Hysteroscopic Cryomyolysis for the Treatment of Submucosal LeiomyomataNo drug interventionstreatmentNot Availablecompleted
NCT00953641
Vaginal Misoprostol for Cervical Ripening Prior to Endometrial Biopsytreatment3withdrawn
NCT05922657
A Registry to Gather Real World Use Data on the Cerene® Cryotherapy DeviceNo drug interventionsNot AvailableNot Availablerecruiting
NCT01124357
A Study to Compare the Effectiveness of Two Different Outpatient Endometrial Ablation Techniques Used for Heavy PeriodsNo drug interventionstreatmentNot Availablecompleted
NCT02642926
Comparison of the Efficiency of Bipolar Energy Versus Monopolar Energy in Endometrial Ablation in Women Having MenorrhagiaNo drug interventionstreatmentNot Availablecompleted
NCT02118974
Randomized Clinical Trial Comparing Conventional Laparoscopic and Robot-Assisted Laparoscopic HysterectomyNo drug interventionstreatmentNot Availablecompleted
NCT02519231
Copper IUD Treatment Observation Studytreatment4completed
NCT02835391
PerClot Compared to Usual Care in Gynaecology ProceduresNo drug interventionstreatmentNot Availablecompleted
NCT00100191
Emmy Trial: Uterine Artery Embolization (UAE) Versus Hysterectomy for Uterine FibroidsNo drug interventionstreatment3completed
NCT03670680
Efficiency of Lina LibrataTM SystemNo drug interventionstreatmentNot Availablerecruiting
NCT01865929
Minimally Invasive Benign HysterectomyNo drug interventionstreatmentNot Availablecompleted
NCT05538689
Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL)No drug interventionstreatment4recruiting
NCT01934244
Post Approval NovaSure Essure Labeling StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00628901
A Prospective Study Comparing Contour SE™ Microspheres to Embosphere® Microspheres for Treating Symptomatic Uterine Fibroids With Uterine Fibroid Embolization (UFE)No drug interventionstreatment4completed
NCT01643304
A Swedish Questionnaire Study to Investigate the Perception of Menstrual BleedingsNo drug interventionsNot AvailableNot Availablecompleted
NCT00386308
Efficacy and Safety Study of XP12B in Women With MenorrhagiaNo drug interventionstreatment3completed
NCT01436903
Chances for Success of CavatermTM Surgery as a Function of Uterus Probe LengthNo drug interventionstreatment4completed
NCT01539187
Fibroid Ablation Study - Large FibroidsNo drug interventionstreatmentNot Availableterminated
NCT01998854
Observational Prospective Study on Patients With Symptomatic Uterine Fibroids Treated With VizAblate® Intrauterine-ultrasound Guided RF AblationNo drug interventionsNot AvailableNot Availableterminated
NCT01829451
Hyaluronic Acid Gel in Prevention of Intrauterine Adhesions After Endometrial AblationNo drug interventionspreventionNot Availablecompleted
NCT01197547
Registry Study of Genesys HTA for Treatment of MenorrhagiaNo drug interventionstreatmentNot Availablecompleted
NCT01979861
Safety & Effectiveness Study of AEGEA Vapor System to Treat Excessive Uterine BleedingNo drug interventionstreatment3unknown_status
NCT02449161
The Effect of Post Ablation Medroxyprogesterone Acetate on Endometrial Amenorrhea RatesNo drug interventionstreatment3terminated
NCT00401193
Efficacy and Safety of XP12B in Women With MenorrhagiaNo drug interventionstreatment3completed
NCT00904709
The Assessment of Tranexamic Acid in Women With Menorrhagia Who Have Bleeding DisordersNo drug interventionstreatment4completed
NCT00156156
Study of Asoprisnil in the Treatment of Uterine Fibroids.treatment3completed
NCT02475252
Construct Validity of a Diagnostic Hysteroscopy Training ModelNo drug interventionstreatmentNot Availableterminated
NCT03751800
A Study Run at Multiple Study Sites to Test Whether the SAMANTA Questionnaire That is Used to Diagnose Heavy Menstrual Bleeding (HMB), Can Also be Used to Assess Changes of Severity of HMB in Women With HMB Who Are Treated During 12 Months With a Chronic Hormonal TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT00768742
Safety and Effectiveness Study of RF Ablation of Uterine Fibroids to Reduce Menstrual Bleeding: the Fibroid Ablation StudyNo drug interventionstreatmentNot Availablewithdrawn
NCT00094536
Evaluation of Modified Treatment Regimens for Treatment of Heavy Menstrual Bleeding Using the HerOption® SystemNo drug interventionsother4completed
NCT01428713
Tranexamic Acid (TA) vs Combined Oral Contraceptive (COCP) Pilot StudyNo drug interventionstreatmentNot Availablecompleted
NCT02824224
Tamoxifen to Reduce Unscheduled Bleeding in New Users of the Levonorgestrel-releasing Intrauterine System (LNG-IUS)No drug interventionsprevention4completed
NCT01969396
Evaluation of the Goldstein SonoBiopsy™ Catheter for Diagnosing Endometrial PathologyNo drug interventionsNot AvailableNot Availableterminated
NCT01569763
Minerva Pivotal Study to Evaluate Safety and Efficacy of the Aurora Endometrial Ablation System Compared to Hysteroscopic Rollerball AblationNo drug interventionstreatmentNot Availablecompleted
NCT02005263
Hysteroscopic Assessment of Fallopian Tubal PatencyNo drug interventionsdiagnosticNot Availablecompleted
NCT03139422
Treatment of Copper Intra Uterine Device Associated Heavy Menstrual Blood LossNo drug interventionstreatment3unknown_status
NCT01715025
A New Treatment Option for Heavy Menstrual BleedingNo drug interventionstreatment4unknown_status
NCT02228174
Sonography Guided Transcervical Ablation of Uterine FibroidsNo drug interventionstreatmentNot Availablecompleted
NCT02616731
Oral Tranexamic Acid Versus Diosmin for Treatment of Menorrhagia in Women Using Copper IUDNo drug interventionstreatment1 / 2unknown_status
NCT01647360
Severity of Bleeding as a Predictor of Quality of Life (QoL) in Women With Heavy Menstrual Bleeding (HMB) Under Dydrogesterone TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT00288691
Menorrhagia Study in Women With Treatment-resistant MenorrhagiaNo drug interventionstreatment2completed
NCT04267562
Minitouch Endometrial Ablation System Treatment for Menorrhagia: An Evaluation of Safety & EffectivenessNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00883662
Mirena Observational ProgramNo drug interventionsNot AvailableNot Availablecompleted
NCT00496080
Doppler-Guided Uterine Artery Occlusion (DUAO) Device for Fibroid Related BleedingNo drug interventionstreatmentNot Availableterminated
NCT00350480
Treatment of Non-Gestational Acute Uterine Bleeding: A Randomized TrialNo drug interventionstreatmentNot Availablecompleted
NCT00496067
Uterine Artery Occlusion for Fibroid Related BleedingNo drug interventionstreatmentNot Availableterminated
NCT02685501
Menorrhagia, Dysmenorrhea and Iron Deficiency Among Young Women Soldiers and Effect on ActivityNo drug interventionsNot AvailableNot Availableunknown_status
NCT04278404
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)Not AvailableNot Availablerecruiting
NCT05788172
Measuring Menstrual Iron Loss Using the Iron Isotope Dilution TechniqueNo drug interventionsNot AvailableNot Availablecompleted
NCT01651468
The Effect of the Nutraceutical "Hemofix" on the Coagulation SystemNo drug interventionssupportive_careNot Availablewithdrawn
NCT00113568
Safety Study of XP12B in Women With Menorrhagiatreatment3completed
NCT00152269
Treatment of Uterine Fibroids With Asoprisnil(J867)treatment3completed
NCT00319410
Comparison of Two Hysteroscopy ApproachesNo drug interventionsdiagnostic3completed
NCT02304510
Prevalence of Heavy Menstrual Bleeding in Female Population Living in BeijingNo drug interventionsNot AvailableNot Availablecompleted
NCT03642210
Study of a Levonorgestrel 52 mg Intrauterine System for the Treatment of Heavy Menstrual BleedingNo drug interventionstreatment3completed
NCT00160381
A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Uterine Fibroidstreatment3completed
NCT01280981
A Study of Tranexamic Acid (XP12B) in Women With Heavy Menstrual BleedingNo drug interventionstreatment3completed
NCT00156195
Study to Evaluate the Safety of Asoprisnil in the Treatment of Uterine Fibroidstreatment3completed
NCT03317795
Treatment of Heavy Menstrual Bleeding in Women With Uterine FibroidsNo drug interventionstreatment4completed
NCT01190150
Lysteda Pediatric Research Equity Act (PREA) Pharmacokinetic Study in Adolescent Females With Heavy Menstrual BleedingNo drug interventionsNot Available4completed
NCT00156208
Safety of Treatment of Uterine Fibroids With Asoprisniltreatment3completed