Hydrocarbons, Fluorinated

Name
Hydrocarbons, Fluorinated
Accession Number
DBCAT001266
Description

Inert liquid or gaseous halocarbon compounds in which FLUORINE replaces some or all HYDROGEN atoms.

Drugs
DrugDrug Description
DesfluraneA general inhalation anesthetic for inpatient and outpatient surgery in adults.
SevofluraneA inhalation anaesthetic agent used for induction and maintenance of general anesthesia during surgical procedures.
PerflutrenA diagnostic medication to improve contrast during echocardiograms.
RosuvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
2,3,4,5,6-Pentafluorobenzyl AlcoholNot Available
Mdl 101,146Not Available
IDD552Not Available
Hexafluoroacetone HydrateNot Available
PerflubronInvestigated for use/treatment in cardiac surgery, hemorrhage, and ileus.
PriralfinamideInvestigated for use/treatment in pain (acute or chronic).
PerflexaneNot Annotated
PerflenapentDodecafluoropentane is an ingredient in the EMA-withdrawn product EchoGen.
RG-4733Ro4929097 has been used in trials studying the treatment of Sarcoma, LYMPHOMA, Neoplasms, Wilm's Tumor, and OSTEOSARCOMA, among others.
VestipitantVestipitant has been investigated for the treatment of Tinnitus.
EplivanserinEplivanserin has been used in trials studying the treatment of Sleep, Insomnia, Chronic Pain, Fibromyalgia, and Primary Insomnia, among others.
Perfluoro tert-butylcyclohexaneOxycyte has been used in trials studying the treatment of Traumatic Brain Injury.
PerflubutanePerflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. It is a cardiovascular drug designed to enable...
PentafluoropropanePentafluoropropane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).
TransfluthrinTransfluthrin is under investigation in clinical trial NCT02394522 (Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM)).
PerfluorooctaneNot Annotated
BatabulinBatabulin is under investigation in clinical trial NCT00057382 (T138067 Versus Doxorubicin in Chemotherapy-naive, Unresectable, Hepatocellular Carcinoma Patients).
LonaprisanLonaprisan is under investigation in clinical trial NCT00555919 (ZK 230211 in Postmenopausal Woman With Metastatic Breast Cancer).
PerfluorodecalinPerfluorodecalin is under investigation in clinical trial NCT03668665 (Influencing Wound Healing Through the Application of Hyaluronic Acid With Perfluorodecalin and Physalis Angulata Extract After Split Skin Removal From the Thigh...
VolinanserinVolinanserin is under investigation in clinical trial NCT00464243 (Efficacy and Safety of Volinanserin on Sleep Maintenance Insomnia - Polysomnographic Study).
Drugs & Drug Targets
DrugTargetType
DesfluraneNADH-ubiquinone oxidoreductase chain 1target
DesfluraneGlycine receptor subunit alpha-1target
DesfluraneGlutamate receptor 1target
DesfluraneGABA(A) Receptortarget
DesfluranePotassium voltage-gated channel subfamily A member 1target
DesfluraneATP synthase subunit delta, mitochondrialtarget
DesfluraneSerum albumincarrier
DesfluraneCalcium transporting ATPasestarget
DesfluraneCytochrome P450 2E1enzyme
SevofluraneNADH-ubiquinone oxidoreductase chain 1target
SevofluraneGlycine receptor subunit alpha-1target
SevofluraneGlutamate receptor 1target
SevofluraneCytochrome P450 2E1enzyme
SevofluraneSerum albumincarrier
SevofluraneCytochrome P450 2A6enzyme
SevofluraneCytochrome P450 2B6enzyme
SevofluraneCytochrome P450 3A4enzyme
SevofluraneGABA(A) Receptortarget
SevofluraneMitochondrial potassium channeltarget
SevofluraneCalcium transporting ATPasestarget
Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
RosuvastatinCytochrome P450 2C9enzyme
RosuvastatinMultidrug resistance-associated protein 4transporter
RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
RosuvastatinCystine/glutamate transportertransporter
RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
RosuvastatinBile salt export pumptransporter
RosuvastatinATP-binding cassette sub-family G member 2transporter
RosuvastatinSerum albumincarrier
RosuvastatinCanalicular multispecific organic anion transporter 1transporter
RosuvastatinSolute carrier family 22 member 8transporter
RosuvastatinSodium/bile acid cotransportertransporter
RosuvastatinIntegrin alpha-Ltarget
2,3,4,5,6-Pentafluorobenzyl AlcoholAlcohol dehydrogenase 1Ctarget
Mdl 101,146Chymotrypsin-like elastase family member 1target
Mdl 101,146Neutrophil elastasetarget
IDD552Aldose reductasetarget
VestipitantNeurokinin 1 receptortarget
Eplivanserin5-hydroxytryptamine receptor 2Atarget
Eplivanserin5-hydroxytryptamine receptor 2Ctarget
Volinanserin5-hydroxytryptamine receptor 2Atarget