Acromegaly (DBCOND0000951)

Identifiers

Synonyms
Acromegalic / Acromegaly (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Arginine
An amino acid commonly found as a component of total parenteral nutrition.
Bromocriptine
A dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome.
Lanreotide
A somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly.
Octreotide
A peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors.
Pasireotide
A somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate.
Pegvisomant
A growth hormone receptor antagonist used to treat acromegaly.
Somatostatin
A natural peptide hormone used to treat acute bleeding from esophageal varices, gastrointestinal ulcers, and gastritis; prevent pancreatic complications after surgery; and restrict secretions of the upper intestine, pancreas, and biliary tract.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00858143
Non Interventional Study For Patients Treated With Somavert®No drug interventionsNot AvailableNot Availablecompleted
NCT03158090
The Longitudinal Approach to Acromegaly: A Pattern of Treatment and Comparative Effectiveness ResearchNo drug interventionsNot AvailableNot Availablerecruiting
NCT00376064
Efficacy of Octreotide Acetate and Cabergoline in Patients With AcromegalyNo drug interventionstreatment4completed
NCT04844164
Vitamin D Metabolism in Patients With Endocrine DisordersNo drug interventionsbasic_science1completed
NCT00642421
Safety and Biological Activity of C2L-OCT-01 PR in Acromegalic PatientsNo drug interventionstreatment3terminated
NCT01265121
Sleep Apnea Syndrome on Acromegaly: Impact of the Treatment on the Carbohydrates Metabolism.No drug interventionssupportive_careNot Availableunknown_status
NCT03045302
Assessment of BIM23B065, Given as Repeated Subcutaneous Injection in Subjects With AcromegalyNo drug interventionstreatment2terminated
NCT01333384
Study in Polish Acromegalic Patients Treated With Somatuline AutogelNo drug interventionsNot AvailableNot Availablecompleted
NCT00225979
Safety and Efficacy of Long-acting Repeatable Octreotide Acetate for Injectable Suspension vs. Surgery in Treatment-naïve Patients With AcromegalyNo drug interventionstreatment3completed
NCT00647179
Substrate Metabolism and Insulin Sensitivity in Acromegalic Patients Before and After TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT00658879
Long Term Use of Somavert (Pegvisomant) For A Regulatory Post Marketing Commitment PlanNo drug interventionsNot AvailableNot Availablecompleted
NCT01368133
The Observational Study of Growth Hormone-secreting Pituitary TumorsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00915954
Growth Hormone Feedback to Insulin-like Growth Factor-I (IGF-1) and Oral Glucose Tolerance Test (OGTT)No drug interventionsotherNot Availablecompleted
NCT00552851
Changes of Left Ventricular Mass and Cardiac Function in Patients With Active Acromegaly During Treatment With the Growth Hormone Receptor Antagonist Pegvisomanttreatment4unknown_status
NCT00616551
Efficacy and Safety of C2L-OCT-01 PR in Acromegalic Patientstreatment3completed
NCT03252353
Efficacy and Safety of Octreotide Capsules (MYCAPSSA) in Acromegalytreatment3unknown_status
NCT06326853
Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical ModelsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02396953
Study to Determine the Maximum Tolerated Dose, Safety and Tolerability of a Single Dose of Lanreotide Prolonged Release Formulation (PRF) in Subjects With Acromegalytreatment1 / 2completed
NCT00690898
Lanreotide as Primary Treatment for Acromegalic Patients With Pituitary Gland Macroadenomatreatment3completed
NCT00216398
Lanreotide Autogel in Patients With Acromegaly Previously Treated With Octreotide LARNo drug interventionstreatment4completed
NCT01471405
One Year Follow-up of Study 2-79-52030-207 (PRIMARYS) in Acromegalic Patients With MacroadenomaNo drug interventionsNot AvailableNot Availablecompleted
NCT06253897
A Study to Understand Participant's Experiences in Gastro-enteropancreatic Neuroendocrine Tumors (GEP-NETs) and AcromegalyNo drug interventionsNot AvailableNot Availablerecruiting
NCT01819883
Ectopic Lipid Deposition and Insulin Resistance in After Treatment of AcromegalyNo drug interventionsNot AvailableNot Availablecompleted
NCT03673761
Muscle in Acromegaly and Cushing's SyndromeNo drug interventionsNot AvailableNot Availableunknown_status
NCT01794793
Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studiestreatment4completed
NCT02231593
SAGIT for Classification of Patients With Acromegaly in Clinical PracticeNo drug interventionsNot AvailableNot Availablecompleted
NCT00552071
Ultrasound Guided Octreotide LAR Injection in Acromegalytreatment4completed
NCT00934271
Fractionated Stereotactic Radiotherapy in Patients With AcromegalyNo drug interventionsNot AvailableNot Availablecompleted
NCT02005978
Brain-gut Interaction in Irradiated Patients With AcromegalyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00149188
Somatuline Autogel: Acromegaly Self/Partner Injection StudyNo drug interventionstreatment4completed
NCT00921609
Peri-operative Dynamics of the Growth Hormone Axis in Subjects With AcromegalyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02685709
Comparison of Oral Octreotide Capsules to Injectable Somatostatin Analogs in Acromegalytreatment3completed
NCT00993356
Preoperative Lanreotide Treatment in Acromegalic Patients With Macroadenomastreatment2unknown_status
NCT03789656
An Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Edge)treatment2completed
NCT00151437
Canadian Pegvisomant Compassionate Study In Acromegalic PatientsNo drug interventionstreatment4completed
NCT00128232
Safety and Efficacy of Octreotide Long Acting Release (LAR) in Treatment Naïve Acromegalic PatientsNo drug interventionstreatment3completed
NCT06372652
A Phase 1 Study of TE-8214 Solution in Healthy VolunteersNo drug interventionstreatment1not_yet_recruiting
NCT00663000
Glucose Tolerance in Acromegaly: The Influence of GH-excess on Glucose Metabolism and Insulin ResistanceNo drug interventionsNot AvailableNot Availablecompleted
NCT05131100
Korean Regulatory Post Marketing Surveillance for SomavertNot AvailableNot Availablerecruiting
NCT00747500
Non Interventional Post Marketing Programme in AcromegalyNo drug interventionsNot AvailableNot Availablecompleted
NCT00521300
Preoperative Octreotide Treatment of Acromegalytreatment4completed
NCT00005100
Measurement of Outcome of Surgical Treatment in Patients With AcromegalyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02217800
The Effect of Subcutaneous Infusions of 3 Doses of DG3173 on Growth Hormone Levels in Untreated Acromegalicstreatment2completed
NCT00068042
A Study To Compare The Efficacy And Safety Of Pegvisomant To That Of Sandostatin Lar Depot In Patients With AcromegalyNo drug interventionstreatment4completed
NCT01504399
Rhinological Outcomes in Endonasal Pituitary SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT02934399
Dynamic Hormone Diagnostics in Endocrine DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01732406
Acromegaly Treatment Quality of Life StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02115906
Assessment of Changes in Metabolic Activity in Liver & Skeletal Muscle in Patients Suffering From AcromegalyNo drug interventionsNot AvailableNot Availableunknown_status
NCT03967249
Extension Study of IONIS-GHR-LRx Administered to Participants With Acromegaly Being Treated With Long-acting Somatostatin Receptor Ligandstreatment2completed
NCT00461149
Dose Escalation of Octreotide-LAR as First-Line Therapy in Resistant AcromegalyNo drug interventionstreatment4completed
NCT04003519
Study to Predict Lanreotide-induced Disease Activity Normalization in AcromegalyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00242541
Study Assessing the Efficacy and Safety of Octreotide Acetate in Patients With Acromegaly, With Micro or MacroadenomasNo drug interventionstreatment4terminated
NCT01995734
An Open-label, Multi-center, Expanded Treatment Protocol of Pasireotide LAR in Patients With AcromegalyNot AvailableNot Availableapproved_for_marketing
NCT00143416
Long Term Study With B2036-PEGNo drug interventionstreatment3completed
NCT00916916
Lanreotide Levels in AcromegalyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02296216
Late Effects of Radiosurgery on Acromegaly StudyNo drug interventionsotherNot Availablecompleted
NCT00701363
Study to Assess the Efficacy of an Extended Injection Interval Schedule of Lanreotide Autogel in Acromegalic Subjectstreatment4completed
NCT00600886
Safety and Efficacy of Pasireotide Long Acting Release (LAR) vs. Octreotide LAR in Patients With Active Acromegalytreatment3completed
NCT03043586
Treatment Patterns and Treatment Outcomes for AcromegalyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02948322
Cardiac (CMRI) Assessment of AcromegalyotherNot Availablecompleted
NCT05752825
Acromegaly: Balance, Falls and Fracture RiskNo drug interventionsNot AvailableNot Availablecompleted
NCT00686348
Somatuline® Depot (Lanreotide) for Acromegaly Post-Marketing Observational StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00210457
Efficacy and Safety of Lanreotide Autogel (60, 90 or 120 mg) in Acromegalic PatientsNo drug interventionstreatment3completed
NCT02371057
Acromegaly & Sleep ApnoeaNo drug interventionsNot AvailableNot Availablecompleted
NCT02396966
Quality of Life (QoL) in Subjects With Acromegaly Under Lanreotide Autogel® Treatment.No drug interventionsNot AvailableNot Availablecompleted
NCT01538966
Acromegaly Combination Treatment StudytreatmentNot Availableterminated
NCT00635765
Open Label Extension Study Evaluating Safety and Biological Activity of C2L-OCT-01 PR in Acromegalic PatientsNo drug interventionstreatment3completed
NCT00642720
Change in Quality of Life After Addition of Weekly 40 mg Pegvisomant/Placebo in Controlled Acromegalic Patientstreatment4completed
NCT01902420
Aryl Hydrocarbon Receptor Interacting Protein (AIP) Gene Mutations in AcromegalyNo drug interventionsNot AvailableNot Availableunknown_status
NCT05192382
A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (PATHFNDR-2)treatment3active_not_recruiting
NCT01086982
Pharmacodynamics Of Product Octreotide Acetate Lar 30 Mg Compared To Product Sandostatin LAR ®treatment1suspended
NCT02539927
Validation Study of the SAGIT® Instrument in AcromegalyNo drug interventionsNot AvailableNot Availablecompleted
NCT00500227
Predictive Factors of Response to Somatostatin Analogues in Acromegalic Patients With Persistent Disease Following SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT00001860
Sandostatin LAR Depot vs. Surgery for Treating AcromegalyNo drug interventionstreatment2completed
NCT03571594
A Four-Part Study to Assess the Safety, Tolerability, PK and PD of ONO-5788 in Healthy Adult Volunteerstreatment1terminated
NCT00182091
Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone DeficiencyNo drug interventionstreatmentNot Availablecompleted
NCT04076462
A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With Acromegalytreatment3completed
NCT02092129
Pituitary Histopathology and Hyperprolactinaemia and Risk of Glucose Metabolic Disturbances in Acromegaly.No drug interventionsNot AvailableNot Availableunknown_status
NCT01062529
Peripheral Metabolic Effects of Somatostatinbasic_scienceNot Availablecompleted
NCT02111044
Phase II Study With ITF2984 in Acromegalic PatientsNo drug interventionstreatment2completed
NCT04837040
A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of AcromegalyNo drug interventionstreatment3active_not_recruiting
NCT00595140
Acute Application of Pegvisomant and Octreotide in AcromegalyNo drug interventionstreatment4completed
NCT03474601
Seoul National University Pituitary Disease Cohort StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00615004
Cardiovascular Outcome After Surgery or Somatostatin AnaloguesNo drug interventionsNot AvailableNot Availablecompleted
NCT02668172
Pasireotide LAR and Pegvisomant Study in AcromegalyNo drug interventionstreatment4unknown_status
NCT01673646
Efficacy and Safety of Pasireotide LAR (Long-acting Release) in Japanese Patients With Acromegaly or Pituitary GigantismNo drug interventionstreatment2completed
NCT05964712
Effects of Therapies in the Acromegaly Disease: Acral Morpho-functional StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT02427295
Hormonal Outcomes in Acromegalic Patients With Treated Surgery With or Without Long Acting Somatostatin AnaloguesNo drug interventionstreatment4unknown_status
NCT02084095
IGF-I and Free Fatty Acids Isn Glucose Metabolism in AcromegalyNo drug interventionsNot AvailableNot Availablecompleted
NCT05149495
Somatostatin Analogues in the Treatment of Relapsing GH Pituitary Adenomas After SurgeryNo drug interventionsNot AvailableNot Availableunknown_status
NCT02403414
Assessment of Airway in Patients With Acromegaly for Predicting Successful Tracheal IntubationNo drug interventionsNot AvailableNot Availableunknown_status
NCT06344650
Cellular, Molecular and Clinical Determinants of Bone Strength in in Vivo and Human Models of GH Excess.No drug interventionsNot AvailableNot Availablerecruiting
NCT00765323
Efficacy and Safety Study of Octreotide Implant in Patients With AcromegalyNo drug interventionstreatment3terminated
NCT01809808
A Prospective Study of Outcome After Therapy for AcromegalyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00383708
Lanreotide Autogel and Pegvisomant Combination Therapy in Acromegalic PatientsNo drug interventionstreatment3completed
NCT03401008
Buccodental Manifestations in Patients With AcromegalyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02354508
Pasireotide in Patients With Acromegaly Inadequately Controlled With First Generation Somatostatin AnaloguesNo drug interventionstreatment3completed
NCT05431803
Real-World Study (RWS) of Lanreotide Autogel (LAN) for the Treatment of Patients With Acromegaly in ChinaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01000090
Surgical Versus Medical Treatment of AcromegalyNo drug interventionsNot AvailableNot Availablecompleted
NCT01752621
Epidemiology of Acromegaly in Denmark 1991-2010No drug interventionsNot AvailableNot Availableunknown_status
NCT02698384
Therapeutic Strategies in Acromegalic Subjects Treated With Lanreotide 120mgNo drug interventionsNot AvailableNot Availableterminated
NCT05401084
Diet in the Management of AcromegalyNo drug interventionstreatmentNot Availablerecruiting
NCT00703079
Impact of Somatostatin Analogs vs. Surgery on Glucose Metabolism in AcromegalyNo drug interventionsNot AvailableNot Availablecompleted
NCT00652379
Co-treatment With Pegvisomant and a Somatostatin Analogue (SA) in SA-responsive Acromegalic PatientsNo drug interventionstreatmentNot Availablecompleted
NCT00638287
Inter-Assay Growth Hormone and IGF-I VariabilityNo drug interventionsNot AvailableNot Availablewithdrawn
NCT02235987
Single Dose Pharmacology Study of DG3173 and Octreotide in Acromegalic Patients.No drug interventionstreatment2completed
NCT02807233
Lanreotide Autogel 120 mg at Extended Dosing Intervals (>4 Weeks) in Acromegalic SubjectsNo drug interventionsNot AvailableNot Availablecompleted
NCT01371045
Oral Glucose Tolerance Testing (OGTT) on Patients Taking Somatostatin AnalogsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00145405
Comparable Effects of Lanreotide Autogel and Octreotide LAR on GH, IGF-I Levels and Patient SatisfactionNo drug interventionstreatment4completed
NCT00372697
Efficacy/Safety of Octreotide Acetate in Patients With Uncontrolled AcromegalyNo drug interventionstreatment3completed
NCT02060383
Study of Management of Pasireotide-induced Hyperglycemia in Adult Patients With Cushing's Disease or AcromegalyNo drug interventionssupportive_care4completed
NCT02274311
Clomiphene Citrate for Treatment of AcromegalyNo drug interventionstreatment2completed
NCT01014793
Short and Long Term Efficacy of Combined Cabergoline and Octreotide Treatment in Acromegalic PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00499993
Efficacy and Tolerability of Lanreotide (Autogel 120 mg) in Patients With AcromegalyNo drug interventionstreatment3completed
NCT00461188
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPANo drug interventionsNot AvailableNot Availablerecruiting
NCT00315107
Estrogen Treatment in Acromegalic WomenNo drug interventionsNot Available2unknown_status
NCT04529356
The TMS Treatment for Postoperative Headache in GH TumorNo drug interventionstreatmentNot Availableunknown_status
NCT02952885
Strict IGF-1 Control in AcromegalyNo drug interventionstreatment3completed
NCT03548415
Safety, Tolerability, and Efficacy of IONIS-GHR-LRx in Participants With Acromegaly Being Treated With Long-acting Somatostatin Receptor LigandsNo drug interventionstreatment2completed
NCT04860037
Micromegaly and Discrepancy Between Growth Hormone and IGF1 at the Diagnosis and Follow-up of Acromegalic PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04138537
Olfactory Function and Olfactory Bulb Volume in Acromegaly PatientsNo drug interventionsotherNot Availablecompleted
NCT00004332
Study of the Effect of Growth Hormone-Releasing Hormone Antagonist on Growth Hormone Release in AcromegalyNo drug interventionsNot AvailableNot Availablecompleted
NCT01302652
Effect of Growth Hormone (GH) on Cardiac Echos in GH Deficient Patients After Acromegaly TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT01261000
Tissue Biomarker for Pegvisomant ActionNo drug interventionstreatmentNot Availablecompleted
NCT01568359
Calcium Homeostasis in Acromegaly: Effect of Surgical/Medical Treatment and Comparison With Nonfunctioning Pituitary TumorsNo drug interventionsNot AvailableNot Availablecompleted
NCT01029275
Somatostatin Analog Treatment of Acromegaly Before Pituitary Surgery : Comparison With Neurosurgery AloneNo drug interventionsNot AvailableNot Availablecompleted
NCT01278342
Study to Evaluate the Efficacy and Safety of Sandostatin LAR at High Dose or in Combination Either With GH-receptor Antagonist or Dopamine-agonist in Acromegalic PatientsNo drug interventionstreatment4completed
NCT02020499
Predictive Factors StudyNo drug interventionsNot AvailableNot Availableterminated
NCT00447499
Assessment of the Ability of Subjects With Acromegaly or Their Partners to Administer Somatuline AutogelNo drug interventionstreatment3completed
NCT03710499
Rehabilitation Program in Patients With AcromegalyNo drug interventionstreatmentNot Availableunknown_status
NCT01840449
Somatuline Predictive Factors in Acromegaly and NETNo drug interventionsNot AvailableNot Availablecompleted
NCT04125836
A Trial to Assess the Long-term Safety of Octreotide Subcutaneous Depot in Patients With AcromegalyNo drug interventionstreatment3active_not_recruiting
NCT01618513
Treatment of Acromegaly With Somatostatin Analogs: GH vs. IGF-I as Primary Biochemical TargetNo drug interventionstreatment4completed
NCT01424241
Effects of Sandostatin LAR® in AcromegalyNo drug interventionstreatment4completed
NCT01861717
A Pilot Study of Pre- and Post-operative Use of Somatuline Depot.No drug interventionstreatment4terminated
NCT02493517
Efficacy and Safety of Lanreotide Autogel® 60, 90 or 120 mg With Lanreotide 40 mg Prolonged Release (PR) in AcromegalyNo drug interventionstreatment3completed
NCT01412424
Efficacy and Safety of Octreotide (MYCAPSSA™ [Formerly Octreolin™]) for AcromegalyNo drug interventionstreatment3completed
NCT01612624
Prospective Study on Changes in AcromegalyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02152124
Growth Hormone, IGF-1 and Medical Treatment in Acromegaly: Are There Effects on Gut Hormone Physiology and Postprandial Substrate Metabolism?No drug interventionsNot AvailableNot Availablecompleted
NCT05069324
PegvisOMant and the Immune SystEm (PROMISE)No drug interventionsNot AvailableNot Availablecompleted
NCT00627796
Lanreotide Autogel-120 mg as First-Line Treatment of AcromegalyNo drug interventionstreatment4completed
NCT00171886
Octreotide Efficacy and Safety in First-line Acromegalic PatientsNo drug interventionstreatment4completed
NCT04349839
ACRODAT Prospective Evaluation StudyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00171730
An Extension Study to Assess the Long-Term Safety and Efficacy of Pasireotide in Participants With AcromegalyNo drug interventionstreatment2completed
NCT01723748
Somatostatin Analogue Treatment of Acromegaly: Molecular AspectsNo drug interventionsbasic_scienceNot Availablecompleted
NCT03042026
Developing a Simple Recognition System of AcromegalyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00234520
A Study to Evaluate the Risk of Developing a Heart Condition Called Valvular Regurgitation in Patients With Acromegaly Treated With Either Lanreotide or OctreotideNo drug interventionsNot AvailableNot Availablecompleted
NCT00446082
Study of Pasireotide Long Acting Release (LAR) Injection in Patients With Acromegaly and Patients With Carcinoid DiseaseNo drug interventionstreatment1completed
NCT00088582
Study Comparing SOM230 Subcutaneously and Sandostatin Subcutaneously in Acromegalic PatientsNo drug interventionstreatment2completed
NCT01137682
Efficacy and Safety of Pasireotide Long Acting Release (LAR) Versus Octreotide LAR or Lanreotide Autogel (ATG) in Patients With Inadequately Controlled AcromegalyNo drug interventionstreatment3completed
NCT05184231
Patient and Physician Survey on Satisfaction With Somatostatin Analogue (SSA) Injections in Acromegaly in ChinaNo drug interventionsNot AvailableNot Availablewithdrawn
NCT05761431
A Single-dose Study of Octreotide Injection in Healthy Adult SubjectsNo drug interventionstreatment1completed
NCT00444873
Effect of 120mg Somatuline Autogel at Different Dose Intervals (28, 42 or 56 Days) in Patients With AcromegalyNo drug interventionstreatment3completed
NCT03431727
Acromegaly - Before and After TreatmentNo drug interventionsNot AvailableNot Availableunknown_status
NCT02012127
Description of Sign-and-symptom Associations at Acromegaly Diagnosis.No drug interventionsNot AvailableNot Availablecompleted
NCT01295060
Long-term Safety and Efficacy Study of Octreotide Implant in Patients With AcromegalyNo drug interventionstreatment3terminated
NCT00517491
Study to Evaluate Patients With Acromegaly Treated With Lanreotide Autogel (Somatuline ATG)No drug interventionstreatment2withdrawn
NCT05298891
Hypoproteic Diet in AcromegalyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04522180
A Study to Assess the Safety, Tolerability, and Efficacy of IONIS-GHR-LRx Administered in Patients With AcromegalyNo drug interventionstreatment2completed
NCT00068029
Pegvisomant And Sandostatin LAR Combination StudyNo drug interventionstreatment4completed
NCT02299089
Phase II Study of Subcutaneous Inj. Depot of Octreotide in Patients With Acromegaly and Neuroendocrine Tumours (NETs)No drug interventionstreatment2completed
NCT05364944
A Study to Assess the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Debio 4126 in Participants With Acromegaly or Functioning Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs)No drug interventionstreatment1active_not_recruiting
NCT03225040
Bone MicroArchitecture in AcromegalyNo drug interventionsNot AvailableNot Availablecompleted
NCT00461240
Cardiac and Skeletal Muscle Energy Metabolism in Abnormal Growth Hormone StatesNo drug interventionsNot AvailableNot Availablecompleted
NCT02020967
Programme of Acromegaly Screening in Patients With Associated Somatic DisordersNo drug interventionsNot AvailableNot Availablecompleted
NCT03849872
Single-dose Study to Evaluate the Absolute Bioavailability and Mass Balance of ONO-5788No drug interventionstreatment1completed
NCT00234572
Efficacy and Safety Study of Varying Doses of Lanreotide Autogel in Patients With AcromegalyNo drug interventionstreatment2 / 3completed
NCT04066569
Reproducibility and Utility of OGTT in AcromegalyNo drug interventionsdiagnosticNot Availableunknown_status
NCT04520646
A Pilot Study of Empagliflozin in the Treatment of Acromegalic CardiomyopathyNo drug interventionstreatmentNot Availableunknown_status
NCT04261712
A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)No drug interventionstreatment2active_not_recruiting
NCT00001981
The Treatment and Natural History of AcromegalyNo drug interventionsNot AvailableNot Availablecompleted
NCT00994214
Study to Assess the Efficacy and Safety of Repeated Administration of BIM 23A760 in Patients With AcromegalyNo drug interventionstreatment2terminated
NCT00913055
Open Label Study of Octreotide Implant in Patients With AcromegalyNo drug interventionstreatment2completed
NCT03792555
A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Evolve)No drug interventionstreatment2completed
NCT03613623
Acromegaly: Patient And Physician PerspectivesNo drug interventionsNot AvailableNot Availablecompleted
NCT00616408
Prediction of Tumor Shrinkage in AcromegalyNo drug interventionsNot AvailableNot Availablecompleted
NCT00531908
Physiopathology of Sodium Retention in AcromegalyNo drug interventionstreatmentNot Availablecompleted