Advanced Breast Cancer (DBCOND0031019)

Identifiers

Synonyms
Advanced Breast cancer / Malignant neoplasm of breast / Malignant breast neoplasm / Breast cancer / Breast tumor malignant / Breast tumour malignant / Breast cancer NOS / Breast cancer stage unspecified / Ca breast

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Anastrozole
A competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women.
Elacestrant
An estrogen receptor antagonist used to treat ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy.
Fulvestrant
An estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-.
Goserelin
A synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary.
Letrozole
An aromatase inhibitor used to treat breast cancer in postmenopausal women.
Metenolone
An anabolic steroid indicated in the treatment and prevention of muscle wasting due to diseases, drug treatments, or other catabolic processes.
No drug targets
Palbociclib
An endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
Ribociclib
A kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04728035
Study of Irinotecan Liposome Injection in Patients With Advanced Breast Cancetreatment1completed
NCT02599363
A Trial of Ribocilcib (LEE011) and Weekly Paclitaxel in Patients With Rb+ Advanced Breast Cancertreatment1completed
NCT03474822
Plasmodium Immunotherapy for Breast and Liver CancersNo drug interventionstreatment1 / 2recruiting
NCT03282825
Clinical Study of Decitabine and Paclitaxel Combination Therapytreatment1unknown_status
NCT00754325
Randomized Trial of Fulvestrant With or Without Dasatinib in Men and Postmenopausal Women Who Have Hormone Receptor-positive Advanced Breast Cancer Previously Treated With an Aromatase Inhibitortreatment2completed
NCT05861830
Dalpiciclib With Endocrine Therapy for Advanced Breast Cancer After CDK4/6 Inhibitor Failure (DAWNA-FES)treatment3recruiting
NCT00305448
A Clinical Trial to Compare Efficacy and Tolerability of Fulvestrant 250mg, 250mg (Plus 250mg Loading Regimen) and 500mgtreatment2completed
NCT00322348
Study of Zoladex Given Every 12 Weeks Versus Given Every Month in Advanced Breast Cancer (ABC) Pre-menopausal Womentreatment2completed
NCT02580448
CYP17 Lyase and Androgen Receptor Inhibitor Treatment With Seviteronel Trial (INO-VT-464-006; NCT02580448)treatment1 / 2completed
NCT03071926
Metronomic PLD in Patients With Primary Endocrine Resistant ABCtreatment2unknown_status
NCT05812326
PD-1 Knockout Anti-MUC1 CAR-T Cells in the Treatment of Advanced Breast CancerNo drug interventionstreatment1 / 2completed
NCT00496366
Capecitabine (Xeloda) and Lapatinib (Tykerb) as First-line Therapy in HER2/Neu-positive Breast Cancertreatment2terminated
NCT05876065
Capecitabine and Cyclophosphamide (XC) as Maintenance Therapy for Advanced Breast CancertreatmentNot Availablerecruiting
NCT05753865
A Study to Evaluate the Efficacy and Safety in Patients With Advanced Breast Cancer Treated With SYHX2011 Compared to Paclitaxel for Injection (Albumin-bound)treatment3not_yet_recruiting
NCT00428220
A Continuation Study Using Sunitinib Malate For Patients Leaving Treatment On A Previous Sunitinib Study.treatmentNot Availablecompleted
NCT04655573
A Pilot Study of a Micro-Organosphere Drug Screen Platform to Lead Care in Advanced Breast CancerNo drug interventionsNot AvailableNot Availableterminated
NCT03850873
A Phase I Study of TQB3616 on Tolerance and PharmacokineticsNo drug interventionstreatment1unknown_status
NCT04227327
Study Evaluating Abemaciclib + Aromatase Inhibitors in HR+, HER2- Advanced Breast Cancer Patients (HERMIONE-7)treatment2active_not_recruiting
NCT02091960
A Study to Assess the Efficacy and Safety of Enzalutamide With Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2 Positive (HER2+), Androgen Receptor Positive (AR+) Metastatic or Locally Advanced Breast Cancertreatment2completed
NCT06107894
TIL Therapy for Patients With Advanced Solid Tumorstreatment1not_yet_recruiting
NCT03025880
Trial to Evaluate Efficacy and Safety of Pembrolizumab and Gemcitabine in HER2-negative ABCtreatment2completed
NCT03047889
A Nation-wide Multicenter Clinical Epidemiologic Study of Chinese Females With Advanced BreastNo drug interventionsNot AvailableNot Availableunknown_status
NCT06157892
A Study of Disitamab Vedotin Alone or With Other Anticancer Drugs in Solid Tumorstreatment1 / 2recruiting
NCT03072992
"Curcumin" in Combination With Chemotherapy in Advanced Breast Cancertreatment2completed
NCT01836640
Developing Plasma DNA as a Surrogate for Tumor Biopsy to Identify Tumor Genetic Alterations in Patients With Advanced Breast CancerNo drug interventionsNot AvailableNot Availableterminated
NCT00452140
Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer Progressing After Endocrine Treatmenttreatment2terminated
NCT04653740
Omic Technologies to Track Resistance to Palbociclib in Metastatic Breast CancerNo drug interventionsotherNot Availableunknown_status
NCT00398567
A Phase 1/2 Study Of HKI-272 (Neratinib) in Combination With Trastuzumab (Herceptin) In Subjects With Advanced Breast Cancertreatment1 / 2completed
NCT00546104
Phase II Dasatinib Study in Advanced Breast Cancertreatment2completed
NCT05191004
Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBCtreatment1 / 2withdrawn
NCT06470672
Study of SHR-A1921 Combined Adebrelimab in HR-positive, HER2-negative Advanced Breast Cancertreatment2not_yet_recruiting
NCT05424068
Rehabilitation for People With Advanced CancerNo drug interventionssupportive_careNot Availablerecruiting
NCT03285568
Patterns of Prescribing and Monitoring of PalbociclibNot AvailableNot Availablecompleted
NCT00327769
Faslodex Advanced Breast Cancer Local Chinese Studytreatment3completed
NCT04316169
Hydroxychloroquine, Abemaciclib and Endocrine Therapy in Hormone Receptor Positive (HR+)/Her 2 Negative Breast Cancertreatment1withdrawn
NCT02499146
Palbociclib Pharmacokinetics Study In Postmenopausal Chinese Women With ER (+), HER2 (-) Advanced Breast Cancerother1unknown_status
NCT03245112
Halaven Patient Registry (Metastatic Breast Cancer, MBC)Not AvailableNot Availableunknown_status
NCT04004910
A Study Comparing Immunopheresis® Alone or In Combination With Chemotherapy Versus Chemotherapy Alone in Treatment of Advanced Breast Cancer PatientsNo drug interventionstreatment1 / 2unknown_status
NCT05438810
This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c in Combination With Fluvestrant ± Goseraline Versus Placebo Combined With Fulvestrant ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.treatment3unknown_status
NCT06339281
A Multicenter Clinical Study of Apatinib Mesylate Combined With Doctor's Choice for Advanced Breast Cancertreatment2not_yet_recruiting
NCT05933395
Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitortreatment2recruiting
NCT06354114
A Study to Evaluate the Efficacy and Safety in Subjects With Advanced Breast Cancer Treated With SYHX2011No drug interventionstreatment2not_yet_recruiting
NCT05323955
Secondary BRain Metastases Prevention After Isolated Intracranial Progression on Trastuzumab/Pertuzumab or T-DM1 in Patients With aDvanced Human Epidermal Growth Factor Receptor 2+ brEast Cancer With the Addition of Tucatinibtreatment2recruiting
NCT05654623
A Study to Learn About a New Medicine Called ARV-471 (PF-07850327) in People Who Have Advanced Metastatic Breast Cancer.treatment3recruiting
NCT05255523
Pyrotinib Plus Trastuzumab After First-line TH (P) Treatment With HER-2 Positive Breast Cancerprevention2not_yet_recruiting
NCT06044623
Implementing Geriatric Assessment for Dose Optimization of Cyclin-dependent Kinase (CDK) 4/6-inhibitors in Older Breast Cancer PatientsNo drug interventionstreatment3recruiting
NCT04920708
Fulvestrant, Ipatasertib and CDK4/6 Inhibition in Metastatic ER+/HER2- Breast Cancer Patients Without ctDNA Suppressiontreatment2recruiting
NCT01876238
Feasibility of a Team Approach for Discussing Prognosis and Treatment Goals in Breast CancerNo drug interventionssupportive_careNot Availablecompleted
NCT03312738
A Study of Everolimus Plus Exemestane in Chinese Postmenopausal Women With Estrogen Receptor Positive, Locally Advanced, Recurrent, or Metastatic Breast Cancer After Recurrence or Progression on Non-steroidal Aromatase Inhibitortreatment2completed
NCT06301438
Dalpiciclib in HR+/HER2- ABCNot AvailableNot Availablenot_yet_recruiting
NCT04862143
Pilot Decentralized Clinical Trial in Men and Pre and Post-menopausal Women With Breast Cancer and a Specific Mutation (PIK3CA) Treated With Alpelisib in Combination With Fulvestranttreatment2terminated
NCT05085002
A Study of Lerociclib in Participants With Advanced Breast Cancertreatment2terminated
NCT06047184
Phase I Study of BEBT-209 in Women With Advanced Breast Cancertreatment1active_not_recruiting
NCT04524000
Study Assessing the Efficacy and Safety of Treatment With Alpelisib Plus Fulvestrant in Japanese Men and Postmenopausal Women With Advanced Breast Cancertreatment2active_not_recruiting
NCT04188548
A Study of LY3484356 in Participants With Advanced or Metastatic Breast Cancer or Endometrial Cancertreatment1active_not_recruiting
NCT04222413
Metarrestin (ML-246) in Subjects With Metastatic Solid TumorsNo drug interventionstreatment1recruiting
NCT05274451
A Study to Investigate LYL797 in Adults with Solid TumorsNo drug interventionstreatment1recruiting
NCT06176534
Combination Followed by Maintenance Chemotherapy Versus CDK4/6 Inhibitor Combined With Endocrine Therapy for HR Low/HER2-negative Advanced Breast Cancer: a Prospective, Randomized, Open-label Phase Ⅱ Clinical Trialtreatment2recruiting
NCT06380751
Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancertreatment3recruiting
NCT06555588
Engage Psychosocial Intervention for Cancer SymptomsNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT06548919
Current Status of Treatment for Chinese Patients With ESR1-mutated HR+/HER2-advanced Breast CancerNot AvailableNot Availablerecruiting
NCT06544577
Safety of Elacestrant in ER+/HER2- and ESR1 Mutations MBCNot AvailableNot Availablerecruiting
NCT06525675
Study to Evaluate the Extended Overall Survival (OS) Data From PARSIFAL Study (The PARSIFAL-LONG Study)Not AvailableNot Availableactive_not_recruiting
NCT06016738
OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancertreatment3recruiting
NCT06123988
Prolonged Overnight Fasting and/or Exercise on Fatigue and Other Patient Reported Outcomes in Women With Hormone Receptor Positive Advanced Breast CancerNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT03577197
Southeast Netherlands Advanced Metastatic Breast Cancer RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT06500494
To Describe How Well Vinorelbine Given Orally Works in Patients With a Breast Cancer After 2 Years of TreatmentNot AvailableNot Availablenot_yet_recruiting
NCT06507930
The COMPASSION StudyNo drug interventionshealth_services_researchNot Availablenot_yet_recruiting
NCT06120283
BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumorstreatment1recruiting
NCT05810870
PIK3CA/PTEN-altered Advanced Breast Cancer Treated With MEN1611 Monotherapy or in Combination With Eribulintreatment2recruiting
NCT06263543
Sequencing Antibody Drug Conjugates in ER+/HER2 LOW MBCtreatment2recruiting
NCT06382948
Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.treatment3not_yet_recruiting
NCT06486883
Safety and Efficacy of T-DXd vs. CDK4/6i-based ET as First-line Therapy of HR-positive and HER2-low/Ultralow Advanced Breast Cancer Patients Classified as Non-luminal Subtypetreatment2not_yet_recruiting
NCT03205761
Analysis of Olaparib Response in Patients With BRCA1 and/or 2 Promoter Methylation Diagnosed of Advanced Breast Cancertreatment2completed
NCT04408118
First Line Atezolizumab, Paclitaxel, and Bevacizumab (Avastin®) in mTNBCtreatment2completed
NCT05216432
First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Advanced Solid Tumor Patients and in Combination With Fulvestrant in Patients With Advanced Breast Cancertreatment1recruiting
NCT06447623
Apatinib Combined With cdk4/6i in First-line Treatment for HR+/HER2- SNF4 Subtype Breast Cancertreatment3recruiting
NCT04482244
RCT of CBD for Anxiety in Advanced Breast Cancertreatment2active_not_recruiting
NCT05077449
A Study of XZP-3287 in Combination With Fulvestrant in Patients With Advanced Breast Cancertreatment3active_not_recruiting
NCT06433609
Study of ADCs Combined With Adebrelimab in HER2-negative Advanced Breast Cancertreatment2not_yet_recruiting
NCT05893368
New Model for Integrating Person-based Care (PbC) in the Treatment of Advanced HER2-negative Breast CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT05142475
Study on TIL for the Treatment of Advanced Breast CancerNo drug interventionstreatment0recruiting
NCT06125834
Trastuzumab Emtansine (T-DM1) in HER2-positive Breast Cancer Patients With Progressive Disease After TKIs or HP Therapytreatment2recruiting
NCT06375707
Efficacy and Safety of Ribociclib in Combination With NSAI Versus Physician's Choice of Chemotherapy Sequential Endocrine Therapy in HR+/HER2- Advanced Breast Cancertreatment2recruiting
NCT05063786
Trastuzumab + Alpelisib +/- Fulvestrant vs Trastuzumab + CT in Patients With PIK3CA Mutated Previously Treated HER2+ Advanced BrEasT Cancer (ALPHABET)treatment3active_not_recruiting
NCT06298084
Dose-Expansion Modular Study To Explore the Safety, Tolerability, and Anti-tumor Activity of HER3- DXd Monotherapy and Combinations in Patients With Inoperable Advanced Breast Cancer (ABC) After Progression on T-DXdtreatment1 / 2recruiting
NCT06328387
HCQ+ADC vs ADC in the Treatment of Advanced Breast Cancertreatment1 / 2recruiting
NCT06338605
Evaluating the Incidence of Pseudo-Acute Kidney Injuries in Patients With Metastatic Breast Cancer on CDK4/6 Inhibitors Trough Cystatin C AnalysisNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05631795
Study to Assess the Safety of Alpelisib Plus Fulvestrant, in Men and Post-menopausal Women With HR-positive, HER2-negative, Advanced Breast Cancer (aBC) With PIK3CA Mutation, Whose Disease Progressed on or After Endocrine Treatmenttreatment4recruiting
NCT05383170
A Study to Evaluate the Safety and Efficacy of CyPep-1 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic Cancerstreatment1 / 2active_not_recruiting
NCT06217185
The Efficacy and Safety of Pyrotinib, Trastuzumab Combined With Taxanes in the Treatment of Trastuzumab-treated HER2+ Advanced Breast Cancer (ABC).treatment4recruiting
NCT06290466
Clinical Study on Pharmacokinetics of FCN-437c Capsule and Its Effect on QT Interval in Healthy SubjectsNo drug interventionstreatment1completed
NCT05759949
First-in-Human Study of RLY-5836 in Advanced Breast Cancer and Other Solid Tumorstreatment1active_not_recruiting
NCT05949541
Efficacy of Everolimus Combined With First-line Endocrine Therapy for HR+/HER2- SNF1-subtype Advanced Breast Cancertreatment2recruiting
NCT05594095
SNF Platform Study of HR+/ HER2-advanced Breast Cancertreatment2recruiting
NCT02768337
Cambridge Brain Mets Trial 1other1 / 2terminated
NCT03878823
Safety and Pharmacokinetics of ODM-209No drug interventionstreatment1 / 2completed
NCT05508906
Phase 1b Combo w/ Ribociclib and Alpelisibtreatment1recruiting
NCT06102824
Organoid-based Functional Precision Therapy for Advanced Breast Cancertreatment2recruiting
NCT05173103
Retrospective Study of 2nd-line Therapies After CDK4/6i + Hormonal Therapy in HR+/HER2- Advanced Breast CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT06193525
FUnctional Selection of Advanced Breast Cancer Patients for Talazoparib Treatment Using the REpair Capacity (RECAP) Testtreatment2recruiting
NCT03052634
A Study of RC48-ADC in Subjects With Advanced Breast CancerNo drug interventionstreatment1 / 2completed
NCT03669497
Hypo-Fractionated Radiotherapy in Breast CancerNo drug interventionstreatmentNot Availablecompleted
NCT04714619
CB-103 Plus NSAI In Luminal Advanced Breast Cancertreatment2terminated
NCT02422615
Study of Efficacy and Safety of LEE011 in Men and Postmenopausal Women With Advanced Breast Cancer.treatment3completed
NCT03481998
A Study of SHR6390 in Combination With Letrozole or Anastrozole or Fulvestrant in Patients With HR Positive and HER2 Negative Advanced Breast Cancertreatment1 / 2completed
NCT03685331
HOPE: Olaparib, Palbociclib and Fulvestrant in Patients With BRCA Mutation-associated, HR+, HER2-metastatic Breast Cancertreatment1active_not_recruiting
NCT06098599
Comparing the Pharmacokinetic Profile of LY01612 and CAELYX® in Chinese Subjects With Advanced Breast Cancertreatment1completed
NCT05655598
TAS-116 Plus Palbociclib in Breast and Rb-null Cancertreatment1recruiting
NCT03809988
PALbociclib Rechallenge in horMone Receptor-posItive/HER2- Negative Advanced Breast Cancer (PALMIRA)treatment2completed
NCT04420598
DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Diseasetreatment2completed
NCT03280303
Palbociclib in Real World PracticeNo drug interventionsNot AvailableNot Availablecompleted
NCT04541225
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid TumorsNo drug interventionstreatment1terminated
NCT04304352
Metronomic Oral Chemotherapy With Cyclophosphamide, Capecitabine and Vinorelbine in Metastatic Breast Cancer Patientstreatment2recruiting
NCT04756765
Talazoparib Monotherapy in PALB2 Mutation Associated Advanced Breast Cancertreatment2recruiting
NCT04942054
A Study in Patients With Advanced Breast CancerNo drug interventionstreatment1terminated
NCT05831878
RC48-ADC in HER2-low Advanced Breast CancertreatmentNot Availablerecruiting
NCT04097756
A Phase I Study of LX-039 TabletsNo drug interventionstreatment1completed
NCT05452213
Comprehensive Analysis of Spatial, Temporal and Molecular Patterns of Ribociclib Efficacy and Resistance in Advanced Breast Cancer Patientstreatment4recruiting
NCT04733417
A Study of SHR6390 Combined With Famitinib in the Treatment of HR + / HER2- Advanced Breast Cancer.treatment2active_not_recruiting
NCT02027376
Study of LDE225 (Sonidegib) in Combination With Docetaxel in Triple Negative (TN) Advanced Breast Cancer (ABC) Patientstreatment1completed
NCT04826016
POL6326 (Balixafortide) Plus Nab-paclitaxel or Eribulin in Patients With HER2-negative Advanced Breast Cancertreatment1 / 2withdrawn
NCT04953377
PFMT Educational Intervention for Patients With Advancer Breast CancerNo drug interventionstreatmentNot Availablerecruiting
NCT05076591
IMM2902, a HER2/SIRPα Bispecific mAb-Trap Antibody-receptor Fusion Protein, in Patients With HER2-expressing Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT05775575
A Clinical Trial of TQB3909 Tablets in Patients With Breast CancerNo drug interventionstreatment1 / 2recruiting
NCT04924699
A Study of MRG002 in the Treatment of Patients With HER2-positive Unresectable Locally Advanced or Metastatic Breast Cancertreatment2 / 3recruiting
NCT02401347
Phase II Trial of Talazoparib in BRCA1/2 Wild-type HER2-negative Breast Cancer and Other Solid Tumorstreatment2completed
NCT03931551
Olaparib+Trastuzumab in HER2[+],Breast Cancer Susceptibility Gene (BRCA) Mutated Advanced Breast Cancertreatment2terminated
NCT03829306
Unraveling KAdcyla Resistance In Human Epidermal Growth Factor Receptor 2(HER2) Positive Advanced Breast Cancer (KATIA)No drug interventionsNot AvailableNot Availablecompleted
NCT05536128
Evaluating the Efficacy and Safety of Fulvestrant Plus DNA Damage Repair Inhibitors After a CDK4/6 Inhibitortreatment2not_yet_recruiting
NCT05530057
Eribulin With or Without Trastuzumab-biosimilar in Patients With HER2-overexpressed Recurrent or Stage IV Breast Cancertreatment2recruiting
NCT05469750
Dalpiciclib Plus Letrozole and Capecitabinetreatment2not_yet_recruiting
NCT05439499
This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c Versus Placebo in Combination With Letrozole or Anastrozole ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.treatment3recruiting
NCT05431504
The Efficacy and Safety of Dalpiciclib Plus Endocrine Therapy in HR-positive / HER2-negative Advanced Breast Cancer Patients With Visceral Crisistreatment2not_yet_recruiting
NCT05337657
A Phase Ib Study of GB491 Plus Letrozole in Patients With Advanced Breast Cancertreatment1recruiting
NCT05274893
A Pharmacokinetic Comparison Study of SYHX2011 and Abraxane® in Patients With Advanced Breast Cancerother1not_yet_recruiting
NCT05257395
A Study of XZP-3287 in Combination With Letrozole/Anastrozole in Patients With Advanced Breast Cancertreatment3not_yet_recruiting
NCT05227131
Margetuximab Plus Tucatinib and Capecitabine in HER2-positive Metastatic Breast Cancertreatment2withdrawn
NCT05156619
Health Care Disparities in Culturally Diverse, Special Needs & Disadvantaged Populations - Bridging the GapNo drug interventionsNot AvailableNot Availablerecruiting
NCT05047848
Clinical Study of Chidamide Combined With Fulvestrant in the Treatment of Hormone Receptor-positive Advanced Breast CancertreatmentNot Availablerecruiting
NCT05020964
Screening Plasma HER2 Amplication by Digital PCR in Advanced Breast Cancer Patients Treated With Trastuzumab and Pyrotinibtreatment2not_yet_recruiting
NCT04892693
Talazoparib in Advanced Breast Cancer Patients With Homologous Recombinant Deficiencytreatment2recruiting
NCT04856371
Study of CYH33 in Combination With Endocrine Therapy With or Without Palbociclib in Patients With HR+, HER2- Advanced Breast Cancertreatment1not_yet_recruiting
NCT04539496
A Phase I/II Study of XZP-3287 in Metastasis Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT04456855
Locoregional Surgery of the Primary Tumor in de Novo Stage IV Breast Cancer PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04436393
Guardant360® Related Clinical Outcomes in Patients Who Share Medical Records-Breast CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT04030728
Implementing Patients´ Competence in Oral Breast Cancer TherapyNo drug interventionsNot AvailableNot Availableunknown_status
NCT03966898
A Study of SHR6390 in Combination With Letrozole or Anastrozole in Patients With HR Positive and HER2 Negative Advanced Breast Cancertreatment3active_not_recruiting
NCT03927456
A Study of SHR6390 in Combination With Fulvestrant in Patients With HR Positive and HER2 Negative Advanced Breast Cancertreatment3active_not_recruiting
NCT03811418
A Study to Compare Pertuzumab + Trastuzumab + Vinorelbine vs. Placebo + Trastuzumab + Docetaxel in Previously Untreated HER2-positive Metastatic Breast Cancerother3withdrawn
NCT03538171
Ph3 Study of Exemestane With or Without Entinostat in Chinese Patients With Hormone Receptor-Positive, Locally Advanced or Metastatic Breast Cancertreatment3active_not_recruiting
NCT03524261
Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Breast CancerNo drug interventionstreatment2withdrawn
NCT03455270
G1T48, an Oral SERD, Alone and in Combination With Palbociclib in ER-Positive, HER2-Negative Advanced Breast Cancertreatment1completed
NCT03405168
Routine Therapy Plus Moxifloxacin in Advanced Breast Cancertreatment2completed
NCT03240224
Bioinformation Therapy for Breast CancerNo drug interventionstreatment2 / 3completed
NCT03182634
The UK Plasma Based Molecular Profiling of Advanced Breast Cancer to Inform Therapeutic CHoices (plasmaMATCH) Trialother2recruiting
NCT03125746
A Study of LXI-15029 in Patients With Advanced Malignant Solid Tumorstreatment1unknown_status
NCT02952729
Study of Antibody Drug Conjugate in Patients With Advanced Breast Cancer Expressing HER2No drug interventionstreatment1completed
NCT02657889
Niraparib in Combination With Pembrolizumab in Patients With Triple-negative Breast Cancer or Ovarian Cancertreatment1 / 2completed
NCT02069093
Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancerprevention2completed
NCT02054338
A Study of Vinflunine Plus Gemcitabine Versus Paclitaxel Plus Gemcitabine in Patients With Advanced Breast Cancertreatment3terminated
NCT01989546
Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutationstreatment1 / 2completed
NCT01976169
Phase 1b Study of PD-0332991 in Combination With T-DM1(Trastuzumab-DM1)treatment1completed
NCT01931943
A Phase Ib Study of Selatinib Ditosilate Tablets in Patients With Advanced Breast CancerNo drug interventionstreatment1unknown_status
NCT01311037
The Combination of GnRh Analogue and Aromatase Inhibitor in Receptor Positive Premenopausal Women With Advanced Breast CancerNo drug interventionsNot AvailableNot Availableunknown_status
NCT00915369
A Clinical Trial to Study the Effects of Nanoparticle Based Paclitaxel Drug, Which Does Not Contain the Solvent Cremophor, in Advanced Breast Cancertreatment1unknown_status
NCT00874146
Level of HER2-neu Gene Amplification an Response to TrastuzumabNo drug interventionsNot AvailableNot Availableunknown_status
NCT00793546
Study Evaluating Bosutinib-Exemestane Combination Vs Exemestane Alone in Post Menopausal Women With Breast Cancertreatment2terminated
NCT00777101
Study Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast Cancertreatment2completed
NCT00719875
HDAC Inhibitor Vorinostat (SAHA) With Capecitabine (Xeloda) Using a New Weekly Dose Regimen for Advanced Breast Cancertreatment1completed
NCT00717951
A Randomised,Multi-Center Study of Docetaxol Plus Capecitabine or Cisplatin in Anthracycline-Pretreated Patients With Advanced Breast Cancertreatment2unknown_status
NCT00635713
Second Line Breast Cancer Trialtreatment3completed
NCT00562458
Non-interventional Study to Evaluate Arimidex in Postmenopausal Women With Advanced Breast CancerNot AvailableNot Availablecompleted
NCT00561119
Maintenance Versus Observation After 6 Cycles of Gemcitabine Plus Paclitaxel in Pts With Advanced Breast Cancertreatment3completed
NCT00522457
Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer After Progression on Trastuzumab Therapytreatment2terminated
NCT00494481
E3 Breast Cancer Taxotere Combinationtreatment2completed
NCT00454805
AZD2171 in Addition to Fulvestrant in Patients With Advanced Breast Cancer.treatment2completed
NCT00452673
Phase I Study of Dasatinib (BMS-354825) and Capecitabine for Women With Advanced Breast Cancertreatment1completed
NCT00445458
A Phase 1/2 Study of HKI-272 (Neratinib) in Combination With Paclitaxel (Taxol) in Subjects With Solid Tumors and Breast Cancertreatment1 / 2completed
NCT00387907
Study of Larotaxel in Combination With Weekly Herceptin® in Patients With HER2 Positive Metastatic Breast Cancertreatment2completed
NCT00328120
Faslodex 500mg Multiple Dose Tolerability Study in BC Patientstreatment1completed
NCT00313170
A Clinical Trial to Compare Efficacy and Tolerability of Fulvestrant 250mg, 250mg Plus 250mg Loading Regimen and 500mgtreatment2completed
NCT00106145
A Notch Signalling Pathway Inhibitor for Patients With Advanced Breast Cancer (0752-014)treatment1completed