NCT06362252
A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03) treatment 1 / 2 recruiting NCT06350162
Testing the Addition of Radiation Therapy to the Immune Therapy Treatment for ES-SCLC treatment 2 recruiting NCT05718323
Niraparib Added to Anti-PD-L1 Antibody Maintenance in SLFN11-positive, Extensive-disease SCLC treatment 2 recruiting NCT06243003
WBRT With Hippocampal-avoidance Technique Followed by SRT for Extensive-stage SCLC With Baseline Brain Metastases No drug interventions treatment 1 / 2 recruiting NCT05933863
Molecular Subtyping of Extensive Stage Small Cell Lung Cancer and Relevent Clinical Significance No drug interventions Not Available Not Available recruiting NCT05505825
A Study of AK104 in Combination With Chiauranib in Patients With Extensive Stage Small Cell Lung Cancer treatment 1 / 2 active_not_recruiting NCT06267170
A Multicenter, Real-world Study of Adebrelimab in the Treatment of Extensive Stage Small Cell Lung Cancer Not Available Not Available not_yet_recruiting NCT05544149
TRT for ES-SCLC After First Line Treatment With Immune Checkpoint Inhibitors No drug interventions treatment 2 recruiting NCT05623319
Pembrolizumab and Olaparib Treatment of Extensive Small Cell Lung Cancer (ES-SCLC) treatment 2 recruiting NCT05595460
Study of RYZ101 in Combination With SoC in Subjects With SSTR+ ES-SCLC treatment 1 recruiting NCT05403723
Adaptive SBRT Plus Chemoimmunotherapy for ES-SCLC treatment 1 suspended NCT04894591
To Assess the Effectiveness and Safety of Zepzelca in Adult Patients With Extensive Stage Small Cell Lung Cancer (SCLC) Not Available Not Available recruiting NCT05002868
Safety, Pharmacokinetics and Anti-tumor Activity of RP12146, in Patients With Solid Tumors No drug interventions treatment 1 completed NCT06211036
Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and Durvalumab treatment 3 recruiting NCT06427369
An Investigational Scan (124I-hJAA-F11 PET/CT) for Diagnosing Lung Cancer No drug interventions diagnostic 1 withdrawn NCT06437509
A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Extensive-stage Small Cell Lung Cancer No drug interventions treatment 2 recruiting NCT06449209
Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy No drug interventions treatment 2 recruiting NCT06586697
First-line Treatment for ES-SCLC with Chemotherapy Combined with PD-1/PD-L1 Inhibitor Sequential Thoracic Radiotherapy No drug interventions treatment 2 recruiting NCT05071703
Evaluation of TRILACICLIB in Chinese Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC) for Chemotherapy-induced Myelosuppression, Antitumor Effects of Combination Regimens, and Safety in a Real-world Study treatment 4 completed NCT04675697
Anlotinib Plus Platinum-etoposide in First-line of Extensive-stage Small-cell Lung Cancer treatment 2 unknown_status NCT05484583
Durvalumab Combined With Consolidation Radiotherapy After First-line Treatment in Extensive Stage Small Cell Lung Cancer With Oligometastases treatment 2 not_yet_recruiting NCT05280470
Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC) treatment 2 active_not_recruiting NCT04878016
A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-PD-L1 Antibody) in Patients With ES-SCLC treatment 3 completed NCT05572476
Lurbinectedin Combined With Durvalumab in Pre-treated Patients With Extensive Stage Small-cell Lung Cancer treatment 2 withdrawn NCT05991180
Real-World Study on the Efficacy of IBI-322 in Combination With Lenvatinib for the Treatment of Extensive Stage Small Cell Lung Cancer No drug interventions Not Available Not Available recruiting NCT05309629
Safety and Efficacy Study of First-line Treatment With QL1706 Plus Chemotherapy in Extensive-Stage Small Cell Lung Cancer treatment 2 active_not_recruiting NCT05668767
Surufatinib in Combination of Durvalumab and EP/EC in the Firstly-line Treatment of ES-SCLC treatment 2 not_yet_recruiting NCT05199272
A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies No drug interventions treatment 1 / 2 active_not_recruiting NCT05092412
Low-dose Radiotherapy Combined With Durvalumab, Chemotherapy(EP) in the Treatment of ES-SCLC treatment 2 active_not_recruiting NCT06332950
Safety and Efficacy of Adebrelimab Plus Irinotecan Liposome (II) With or Without Famitinib in ES-SCLC Pre-treated With Immunotherapy treatment 1 / 2 not_yet_recruiting NCT04985851
To Evaluate the Efficacy of Durvalumab + Anlotinib in Terms of OS and PFS. treatment Not Available active_not_recruiting NCT06008353
A Real-World Assessment of the Demographic, Clinical Characteristics and Outcomes of a Brazilian Cohort of Previously Untreated Extensive Stage-Small Cell Lung Cancer Receiving Durvalumab Combined With Platinum-Etoposide in (ES-SCLC) in Brazil No drug interventions Not Available Not Available recruiting NCT04790253
PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients (PRIMALung Study) No drug interventions treatment Not Available recruiting NCT05761977
Durvalumab in Combination With Standard Chemotherapy of Patients With Extensive Stage Small Cell Lung Cancer No drug interventions Not Available Not Available recruiting NCT06223711
Durvalumab With Consolidative Radiochemotherapy and Ablative Stereotactic Radiotherapy in Oligometastatic ES-SCLC treatment 2 recruiting NCT05588388
Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases treatment 2 recruiting NCT04902885
Phase 3 Study Evaluating Efficacy, Safety and Pharmacokinetics of Trilaciclib In Small Cell Lung Cancer Patients treatment 3 completed NCT01987232
Phase 1b/2 Study of Carfilzomib, Carboplatin, and Etoposide in Patients With Previously Untreated Extensive Stage Small-cell Lung Cancer treatment 1 / 2 completed NCT05068232
Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES) treatment 2 recruiting NCT05765825
Study of Low-Dose Radiotherapy Concurrent Chemotherapy With Serplulimab for Patients With ES-SCLC treatment 2 recruiting NCT06217757
Safety and Tolerability of LDRT+Sugemalimab+Chemotherapy+Olaparib for First-Line Treatment of SLFN-11 Positive ES-SCLC treatment 1 / 2 recruiting NCT04947774
Prophylactic Cranial Irradiation in Extensive-stage Small Cell Lung Cancer No drug interventions Not Available Not Available unknown_status NCT06306560
A Study of Adebrelimab Combined With Famitinib and Chemotherapy in the Treatment of ES-SCLC. treatment 2 not_yet_recruiting NCT05796089
Chemotherapy and Immunotherapy in Extensive-Stage Small-Cell Lung Cancer With Thoracic Radiotherapy treatment 2 recruiting NCT05874401
Trilaciclib vs Placebo in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Receiving Topotecan treatment 4 recruiting NCT06536868
Tislelizumab Combined With Chemotherapy and Thoracic Radiotherapy in ES-SCLC treatment 2 recruiting NCT06227546
MGC018 in Patients With Relapsed or Refractory Extensive-Stage Small-Cell Lung Cancer treatment 2 recruiting NCT06478043
A Study to Investigate the Efficacy and Safety of Ivonescimab Combined With Irinotecan Liposome as Second-line Regimen for ES-SCLC treatment 2 not_yet_recruiting NCT05468489
To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC treatment 3 recruiting NCT05903092
MOnaliZumab in Combination With durvAlumab (MEDI4736) Plus Platinum-based chemotheRapy for First-line Treatment of Extensive Stage Small Cell Lung Cancer treatment 2 recruiting NCT06597513
Auto-HSCT-Supported Dose-Dense Chemotherapy with Adebrelimab As First-Line Treatment for ES-SCLC No drug interventions treatment 1 / 2 not_yet_recruiting NCT06598306
Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308) basic_science 1 recruiting NCT04699838
Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer treatment 2 recruiting NCT05361395
First-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects With Extensive Stage Small Cell Lung Cancer (ES-SCLC) treatment 1 active_not_recruiting NCT02011087
Bioelectrical Impedance Phase Angle in Predicting Treatment Outcome in Patients With Extensive Stage Small Cell Lung Cancer Receiving First-Line Chemotherapy No drug interventions diagnostic Not Available terminated NCT00088933
Vaccine Therapy and Sargramostim With or Without Docetaxel in Treating Patients With Metastatic Lung Cancer or Metastatic Colorectal Cancer treatment 1 terminated NCT01325753
Cryotherapy in Treating Patients With Lung Cancer That Has Spread to the Other Lung or Parts of the Body No drug interventions treatment Not Available withdrawn NCT00528645
AZD0530 in Treating Patients With Extensive Stage Small Cell Lung Cancer treatment 2 completed NCT00057837
Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Extensive-Stage Small Cell Lung Cancer treatment 2 completed NCT05896059
A Study to Investigate the Efficacy and Safety of Tislelizumab Combined With Anlotinib as Maintenance Therapy for ES-SCLC treatment 2 recruiting NCT06016270
A Study of hSTC810 in Combination With Paclitaxel in Relapsed or Refractory Extensive Stage Small Cell Lung Cancer treatment 1 / 2 recruiting NCT05055999
Tumor Microenvironment Surveillance on Simultaneous Liver Metastases Extensive Stage Small Cell Lung Cancer No drug interventions Not Available Not Available completed NCT05142696
A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab treatment 1 / 2 recruiting NCT00544596
R-(-)-Gossypol Acetic Acid, Cisplatin, and Etoposide in Treating Patients With Advanced Solid Tumors or Extensive Stage Small Cell Lung Cancer treatment 1 completed NCT00828139
S0802 - Topotecan With or Without Aflibercept in Treating Patients With Extensive-Stage Small Cell Lung Cancer treatment 2 completed NCT04790539
a Study of SHR1210 in Combination With Paclitaxel-albumin and Carboplatin in Extensive Stage Small Cell Lung Cancer treatment 2 unknown_status NCT01331525
The Addition of Ipilimumab to Carboplatin and Etoposide Chemotherapy for Extensive Stage Small Cell Lung Cancer treatment 2 completed NCT06323265
A Real-world Study of Adebrelimab Combined With Chemotherapy±Chest Radiotherapy in Patients With Extensive Stage Small Cell Lung Cancer Not Available Not Available recruiting NCT02972320
Extensive Stage Sclc Patients Who Were Benefit From First-line Treatment Accept Temozolomide Maintain Therapeutic treatment 2 unknown_status NCT01803269
Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung Cancer treatment 2 terminated NCT00031681
7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) treatment 1 completed NCT00773955
R-(-)-Gossypol Acetic Acid in Treating Patients With Recurrent Extensive-Stage Small Cell Lung Cancer treatment 2 completed NCT00020202
FR901228 in Treating Patients With Refractory or Progressive Small Cell Lung Cancer or Non-small Cell Lung Cancer treatment 2 completed NCT00084487
Rebeccamycin Analog as Second-Line Therapy in Treating Patients With Limited-Stage or Extensive-Stage Small Cell Lung Cancer That Relapsed After Previous First-Line Chemotherapy treatment 2 terminated NCT00470054
Dasatinib in Treating Patients With Relapsed Small Cell Lung Cancer treatment 2 completed NCT00017251
Combination Chemotherapy Plus Oblimersen in Treating Patients With Previously Untreated Extensive-Stage Small Cell Lung Cancer treatment 1 completed NCT05055947
Efficacy Biomarker Investigation on Extensive Stage Small Cell Lung Cancer No drug interventions Not Available Not Available completed NCT00028028
CCI-779 in Treating Patients With Extensive-Stage Small Cell Lung Cancer treatment 2 completed NCT01217411
RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer treatment 1 terminated NCT00042978
Carboplatin and Etoposide With or Without Oblimersen Sodium in Treating Patients With Extensive Stage Small Cell Lung Cancer treatment 2 completed NCT00098956
7-hydroxystaurosporine and Topotecan Hydrochloride in Treating Patients With Relapsed or Progressed Small Cell Lung Cancer treatment 2 completed NCT04213937
Nab-paclitaxel Versus Topotecan As Second-Line Treatment for Patients With Extensive Stage Small Cell Lung Cancer treatment 2 unknown_status NCT04933175
Fluzopalil in Combination With Anlotinib for Extensive Small-cell Lung Cancer treatment 2 unknown_status NCT00019006
Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer No drug interventions treatment 1 completed NCT02194049
Cisplatin, Etoposide and PI3K Inhibitor BKM120 in Treating Patients With Advanced Solid Tumors or Small Cell Lung Cancer treatment 1 completed NCT01935336
Study of Ponatinib in Patients With Lung Cancer Preselected Using Different Candidate Predictive Biomarkers treatment 2 completed NCT00643396
Phase II Trial of Consolidative Thoracic Radiotherapy for Extensive Stage Small Cell Lung Cancer No drug interventions treatment 2 completed NCT01155258
Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors treatment 1 completed NCT00118235
Cisplatin, Irinotecan, and Bevacizumab, in Treating Patients With Small Cell Lung Cancer treatment 2 completed NCT04063163
A Randomized, Double-blind, Placebo Controlled Phase III Study to Investigate Efficacy and Safety of HLX10 + Chemotherapy (Carboplatin- Etoposide) in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) treatment 3 unknown_status NCT00182689
Sorafenib in Treating Patients With Extensive Stage Small Cell Lung Cancer treatment 2 completed NCT00079040
Cisplatin, Etoposide, and Bevacizumab in Treating Patients With Previously Untreated Extensive Stage Small Cell Lung Cancer treatment 2 completed NCT05001412
Chemotherapy Combined With Camrelizumab and Apatinib in First-line Treatment of ES-SCLC treatment 1 unknown_status NCT01999881
Impacts of Exercise on Prognostic Biomarkers in Lung Cancer Patients No drug interventions supportive_care Not Available completed NCT04346914
Study of ZKAB001 Combined With Carboplatin and Etoposide in the Extensive Small Cell Lung Cancer treatment 1 unknown_status NCT06648200
Toripalimab and JS004 Combined With Platinum-based Chemotherapy for Relapsed and Extensive-stage Small Cell Lung Cancer No drug interventions treatment 2 not_yet_recruiting NCT06610734
Evaluating the Efficacy and Safety of Adebrelimab in Combination with Chemotherapy and LDRT As 1L Treatment for ES-SCLC treatment 3 not_yet_recruiting NCT05945745
Molecular Analysis and Treatment Options of SCLC No drug interventions Not Available Not Available recruiting NCT05066945
Application of ctDNA in the Evaluation of Curative Effect and Prognosis of SCLC Patients No drug interventions Not Available Not Available not_yet_recruiting NCT04670445
Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer No drug interventions health_services_research Not Available active_not_recruiting NCT06348797
Phase I Clinical Study of α-PD-L1/DLL3 CAR-T in Patients With R/R SCLC No drug interventions treatment 1 not_yet_recruiting NCT02179528
Study of Small Doses of Etoposide as Maintenance Treatment in Small Cell Lung Cancer(SCLC) treatment 2 unknown_status NCT05703971
Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients treatment 1 / 2 recruiting NCT03923270
Radiotherapy and Durvalumab/Durvalumab Combo (Tremelimumab/Olaparid) for Small Cell Lung Cancer treatment 1 active_not_recruiting NCT06429696
PD-L1 Inhibitor Combined With Apatinib as First-line Maintenance Treatment for Extensive-stage Small Cell Lung Cancer treatment 2 not_yet_recruiting NCT06030258
IN10018 Combination Therapy in Treatment-naïve ES-SCLC treatment 1 / 2 recruiting NCT04967625
A Phase II Study of Sintilimab Combined With Anlotinib in Treatment of ED-SCLC treatment 2 unknown_status NCT06187740
Thoracic Consolidation Radiotherapy for ES-SCLC Treated With Chemo-immunotherapy No drug interventions treatment 1 recruiting NCT05745350
First Line Pembrolizumab, Plinabulin Plus Etoposide and Platinum (EP) for ES-SCLC treatment 2 not_yet_recruiting NCT04659785
A Study of Fluzoparib Combined With Apatinib as Second-Line Treatment of Patients With Extensive Stage Small Cell Lung Cancer（FA-ES-SCLC） treatment 1 / 2 unknown_status NCT05384015
Study of Pembrolizumab, Lenvatinib and Chemotherapy Combination in First Line Extensive-stage Small Cell Lung Cancer treatment 2 recruiting NCT03755115
SHR-1210 Combined With Epirubicin in the Treatment of Extensive Disease Small Cell Lung Cancer treatment 2 unknown_status NCT03325816
Nivolumab and 177Lu-DOTA0-Tyr3-Octreotate for Patients With Extensive-Stage Small Cell Lung Cancer treatment 1 / 2 completed NCT00003496
Antineoplaston Therapy in Treating Patients With Recurrent or Extensive-Stage Small Cell Lung Cancer treatment 2 terminated NCT05680922
DLL3-Directed Chimeric Antigen Receptor T-cells in Subjects With Extensive Stage Small Cell Lung Cancer No drug interventions treatment 1 recruiting NCT04462276
Thoracic RadiothErapy With Atezolizumab in Small Cell lUng canceR Extensive Disease treatment 2 active_not_recruiting NCT03994744
Assessing Safety and Efficacy of Sintilimab and Metformin Combination Therapy in SCLC treatment 2 unknown_status NCT03059667
Immunotherapy as Second-line in Patient With Small Cell Lung Cancer treatment 2 completed NCT05027867
KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung Cancer treatment 2 terminated NCT03253068
Pembrolizumab Plus Amurubicin in Patients With Refractory Small-cell Lung Cancer treatment 2 unknown_status NCT05856695
A Phase II Study Assessing the Efficacy of Etoposide Free Chemotherapy Plus Durvalumab (MEDI4736) in First Line Extensive Disease Small Cell Lung Cancer (SCLC) treatment 2 recruiting NCT02312622
Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer treatment 2 completed NCT03382561
Cisplatin/Carboplatin and Etoposide With or Without Nivolumab in Treating Patients With Extensive Stage Small Cell Lung Cancer treatment 2 active_not_recruiting NCT04334941
Testing Maintenance Therapy for Small Cell Lung Cancer in Patients With SLFN11 Positive Biomarker treatment 2 active_not_recruiting NCT04402788
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial treatment 2 / 3 recruiting NCT06287775
Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer treatment 1 / 2 not_yet_recruiting NCT04919382
Temozolomide and Atezolizumab as Second or Third Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer treatment 2 recruiting NCT05191797
Bomedemstat and Maintenance Immunotherapy for Treatment of Newly Diagnosed Extensive Stage Small Cell Lung Cancer treatment 1 / 2 terminated NCT03896503
Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the Lungs treatment 2 active_not_recruiting NCT05161533
Hypofractionated Radiation Therapy After Durvalumab and Chemotherapy for the Treatment of Stage IV Extensive Stage Small Cell Lung Cancer, CASPIAN-RT Trial treatment 2 withdrawn NCT04696575
Lamivudine in Combination With Chemoimmunotherapy for the Treatment of Extensive Stage Small Cell Lung Cancer treatment 2 recruiting NCT03830918
Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy treatment 1 / 2 recruiting NCT05244239
Palliative Radiotherapy With Lurbinectedin in Patients With Extensive Stage Small Cell Lung Cancer treatment 1 recruiting NCT05339022
Supportive Care Intervention (ROAR-LCT) for Patients With Stage IIIA, IIIB, and IV Lung Cancer, ROAR-LCT Trial No drug interventions supportive_care Not Available recruiting NCT04728230
Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial treatment 1 / 2 recruiting NCT03995667
Tumor Treating Fields (TTFields) Therapy to Manage Brain Metastases in Small Cell Lung Cancer No drug interventions prevention 2 terminated NCT04560972
LB-100, Carboplatin, Etoposide, and Atezolizumab for the Treatment of Untreated Extensive-Stage Small Cell Lung Cancer treatment 1 recruiting NCT04229381
Resiliency Among Older Adults Receiving Lung Cancer Treatment No drug interventions supportive_care Not Available completed NCT00453154
Cisplatin or Carboplatin, and Etoposide With or Without Sunitinib Malate in Treating Patients With Extensive-Stage Small Cell Lung Cancer treatment 1 / 2 completed NCT02899728
Olaparib, Cediranib Maleate, and Standard Chemotherapy in Treating Patients With Small Cell Lung Cancer treatment 2 terminated NCT04155034
S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer No drug interventions treatment 3 recruiting NCT05353439
Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung Cancer treatment 1 suspended NCT04631029
Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread treatment 1 completed NCT06110572
Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation treatment 1 / 2 recruiting NCT06620796
A Phase II Study of Ivonescimab Combined with Cadonilimab and Chemotherapy in Extensive-stage Small Cell Lung Cancer treatment 2 not_yet_recruiting NCT04654364
Lung Cancer Registry No drug interventions Not Available Not Available recruiting NCT04660097
Alotinib Plus Durvalumab-Platinum-Etoposide in First-line Treatment Extensive Small-cell Lung Cancer treatment 2 unknown_status NCT05116007
Anti-PD-1 and VEGF Bispecific Antibody AK112 in Combination With Chemotherapy in Patients With ES-SCLC treatment 1 completed NCT05507593
Study of DLL3-CAR-NK Cells in the Treatment of Extensive Stage Small Cell Lung Cancer treatment 1 unknown_status NCT04731909
Toripalimab Combined With Anlotinib, Etoposide and Platinum in the Treatment of Extensive-stage Small Cell Lung Cancer treatment Not Available unknown_status NCT04221529
Patients With ES-SCLC and ECOG PS=2 Receiving Atezolizumab-Carboplatin-Etoposide treatment 2 active_not_recruiting NCT05299255
Utidelone in Third-line and Above Treatment of Small Cell Lung Cancer treatment 2 unknown_status NCT06477523
Phase 1b/2 Study of LDRT in Combination With AK104 Plus Chemotherapy as First-line Treatment for ES-SCLC treatment 1 / 2 recruiting NCT01642251
Cisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung Cancer treatment 1 / 2 completed NCT02402920
Pembrolizumab and Concurrent Chemoradiotherapy or Radiation Therapy in Treating Patients With Small Cell Lung Cancer treatment 1 active_not_recruiting NCT03402880
ALCMI-005: Pembrolizumab and Epacadostat in Treating Patients With Extensive Stage Small Cell Lung Cancer treatment 2 withdrawn NCT03154190
Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer No drug interventions health_services_research Not Available unknown_status NCT01737502
Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer treatment 1 / 2 completed NCT02635009
Whole-Brain Radiation Therapy With or Without Hippocampal Avoidance in Limited Stage or Extensive Stage Small Cell Lung Cancer No drug interventions supportive_care 2 / 3 active_not_recruiting NCT00887159
A Randomized Phase II Study of Cisplatin and Etoposide in Combination With Either Hedgehog Inhibitor GDC-0449 or IGF-1R MOAB IMC-A12 for Patients With Extensive Stage treatment 2 completed NCT02359019
MK-3475 as Maintenance Therapy in Extensive Stage SCLC treatment 2 completed NCT03607682
Tumor-Treating Fields Therapy in Preventing Brain Tumors in Participants With Extensive-Stage Small Cell Lung Cancer No drug interventions treatment Not Available terminated NCT01439568
A Study of LY2510924 in Participants With Extensive-Stage Small Cell Lung Carcinoma treatment 2 completed NCT06646276
A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS). No drug interventions treatment 3 not_yet_recruiting NCT06614621
A Study of Adebelimab Combined With Chemotherapy as a First-line Treatment Sequential Treatment for Extensive-stage Small Cell Lung Cancer treatment 2 not_yet_recruiting NCT03516084
A Study of Niraparib as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Patients With Extensive Stage Small Cell Lung Cancer No drug interventions treatment 3 terminated NCT00791154
QUILT-2.013: First-Line Treatment for Extensive Stage Small Cell Lung Cancer treatment 1 / 2 terminated NCT03135977
Apatinib and Etoposide as the Maintenance Therapy in Extensive-stage Small Cell Lung Cancer After First-line Chemotherapy prevention 2 unknown_status NCT03711305
Study of Carboplatin Plus Etoposide With or Without SHR-1316 in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC) treatment 3 unknown_status NCT02772107
Temozolomide as Maintenance Therapy Following Induction Chemotherapy in Extensive Stage Small Cell Lung Cancer treatment 2 / 3 unknown_status NCT00616109
Sunitinib Maintenance Therapy After Induction Platinum-Based Chemotherapy in Patients With ES-SCLC treatment 2 completed NCT02323737
Phase II Study of Irinotecan and Cisplatin in Extensive-stage Small Cell Lung Cancer treatment 2 completed NCT03043599
Ipilimumab + Nivolumab w/Thoracic Radiotherapy for Extensive-Stage Small Cell Lung Cancer treatment 1 / 2 completed NCT05509699
Surufatinib Plus Anti-PD-1/L1 as Maintenance Therapy in Extensive-Stage Small Cell Lung Cancer treatment 2 recruiting NCT04056949
Efficacy and Safety of IBI308 and Paclitaxel/Albumin Paclitaxel for SCLC Patients Who Failed Etoposide Chemotherapy treatment 2 unknown_status NCT03841136
Anlotinib Combined With Etoposide and Platinum in the Treatment of Lung Cancer treatment 2 unknown_status NCT06554535
Efficacy and Safety of Serplulimab With Chemotherapy and Aspirin in Untreated Extensive-Stage Small Cell Lung Cancer treatment 2 not_yet_recruiting NCT06497530
Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC treatment 2 not_yet_recruiting NCT01563601
Efficacy and Safety of Obatoclax Mesylate in Combination With Carboplatin and Etoposide Compared With Carboplatin and Etoposide Alone in Chemotherapy-Naive Patients With Extensive-Stage Small Cell Lung Cancer treatment 3 withdrawn NCT01076504
A Trial of Amrubicin and Carboplatin With Pegfilgrastim in Patients With Extensive-Stage Small Cell Lung Cancer treatment 2 completed NCT03781869
Study of Anlotinib as the Maintenance Therapy for Extensive-stage Small Cell Lung Cancer treatment 2 unknown_status NCT01555710
Study of Palifosfamide-tris in Combination With Carboplatin and Etoposide in Chemotherapy Naïve Patients With Extensive-Stage Small Cell Lung Cancer (The MATISSE Study) treatment 3 unknown_status NCT03913455
Guadecitabine in Combination With Carboplatin in Extensive Stage Small Cell Lung Cancer treatment 2 completed NCT04404543
A Study of SYHA1807 in Subjects With Extensive-Stage Small Cell Lung Cancer No drug interventions treatment 1 unknown_status NCT04397003
Personalized Neoantigen Vaccine in Combination With Durvalumab (MEDI4736) in Extensive Stage Small Cell Lung Cancer treatment 2 recruiting NCT04254471
This Phase II/III, Multicenter Study is Designed to Evaluate the Safety and Clinical Activity of AL3810 in Patients treatment 2 / 3 unknown_status NCT04487756
Combination of Atezolizumab With Dendritic Cell Vaccine in Patients With Lung Cancer treatment 1 / 2 active_not_recruiting NCT04562337
SHR-1316 Combined With Chemotherapy and Chest Radiotherapy in ES-SCLC treatment 2 active_not_recruiting NCT03085849
SGI-110 Plus Durvalumab/Tremelimumab in SCLC treatment 1 completed NCT03911219
Impact of eHealth Monitoring on Overall Survival in Patients With Metastatic NSCLC / Extensive-stage SCLC / Advanced TNBC Under First-line Treatment With Atezolizumab Plus Chemotherapy No drug interventions Not Available Not Available completed NCT04101357
Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411 treatment 1 / 2 terminated NCT06479473
Radiotherapy to All Residual Lesions After Chemoimmunotherapy No drug interventions treatment 1 / 2 recruiting NCT04636762
A Study of Concurrent Chemoradiation With Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC) No drug interventions treatment 2 completed NCT04702880
A Study of BMS-986012 in Combination With Carboplatin, Etoposide, and Nivolumab as First-line Therapy in Extensive-stage Small Cell Lung Cancer treatment 2 active_not_recruiting NCT04774380
Study of Durvalumab in Combination With Platinum and Etoposide for the First Line Treatment of Patients With Extensive-stage Small Cell Lung Cancer treatment 3 active_not_recruiting NCT05975944
Study of Selinexor Combined With Olaparib in Relapsed/Refractory Extensive Stage Small Cell Lung Cancer treatment 1 / 2 recruiting NCT04373369
Vorolanib + Atezolizumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer treatment 2 active_not_recruiting NCT00682981
A Phase I/II Study of Carboplatin and Etoposide With or Without Obatoclax in Extensive-stage Small Cell Lung Cancer (ES-SCLC) treatment 1 / 2 completed NCT03971214
PD-1 Inhibitors Consolidation in Extensive-stage Small Cell Lung Cancer treatment 1 unknown_status NCT04663438
Real World Study of Efficacy and Safety of Atezolizumab Plus Chemotherapy in Chinese Patients With ES-SCLC No drug interventions Not Available Not Available unknown_status NCT03166254
Personalized Therapeutic Anti-tumor Vaccine With Pembrolizumab and Standard of Care Chemotherapy in Squamous Non-Small Cell Lung Cancer and Extensive Stage Small Cell Lung Cancer treatment 1 withdrawn