Cognitive Dysfunctions

Also known as: Cognition Disorders / Cognitive Disorder / Cognitive Disorders / Cognition Disorder / Cognitive Dysfunction / Cognitive disorder (disorder)

Drug	Drug Name	Drug Description
DB04660	Choline alfoscerate	A natural choline that is used to manage declining cognitive function associated with neurodegenerative and vascular diseases.
DB01381	Ginkgo biloba	A herbal supplement found in over-the-counter or unapproved homeopathic products for various health conditions, such as cognitive, neurodegenerative, cardiovascular, and reproductive health disorders.
DB09210	Piracetam	A nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer.
DB13084	Pyritinol	A vitamin B6 analog indicated as an adjunct therapy in the treatment of a wide variety of disorders of the brain.

Drug	Drug Name	Target	Type
DB04660	Choline alfoscerate	Ganglioside GM2 activator	target
DB01381	Ginkgo biloba	Cytochrome P450 2C9	enzyme
DB01381	Ginkgo biloba	Phospholipase A2, membrane associated	target
DB01381	Ginkgo biloba	Sodium-dependent noradrenaline transporter	target
DB01381	Ginkgo biloba	Glycine receptor subunit alpha-1	target
DB01381	Ginkgo biloba	Gamma-aminobutyric acid receptor subunit alpha-1	target
DB01381	Ginkgo biloba	Gamma-aminobutyric acid receptor subunit beta-2	target
DB01381	Ginkgo biloba	Gamma-aminobutyric acid receptor subunit gamma-2	target
DB01381	Ginkgo biloba	Cytochrome P450 3A4	enzyme
DB01381	Ginkgo biloba	Amine oxidase [flavin-containing] A	target
DB01381	Ginkgo biloba	Nitric oxide synthase, inducible	target
DB01381	Ginkgo biloba	Cytochrome P450 1B1	enzyme
DB01381	Ginkgo biloba	Cytochrome P450 1A1	enzyme
DB01381	Ginkgo biloba	Cytochrome P450 1A2	enzyme

Drug	Drug Name	Phase	Status	Count
DB03756	Doconexent	0	Completed	1
DB00472	Fluoxetine	0	Withdrawn	1
DB01390	Sodium bicarbonate	0	Active Not Recruiting	1
DB00514	Dextromethorphan	1	Completed	1
DB14914	Flortaucipir F-18	1	Completed	1
DB14971	Iomazenil	1	Completed	1
DB11867	JNJ-39393406	1	Terminated	1
DB01017	Minocycline	1	Not Yet Recruiting	1
DB01017	Minocycline	1	Recruiting	1
DB14835	SUVN-G3031	1	Completed	2
DB06151	Acetylcysteine	1 / 2	Completed	1
DB00633	Dexmedetomidine	1 / 2	Unknown Status	1
DB00843	Donepezil	1 / 2	Completed	1
DB00187	Esmolol	1 / 2	Unknown Status	1
DB01221	Ketamine	1 / 2	Completed	1
DB00945	Acetylsalicylic acid	2	Active Not Recruiting	1
DB12274	Aducanumab	2	Terminated	1
DB06413	Armodafinil	2	Completed	1
DB00289	Atomoxetine	2	Terminated	1
DB06090	Bradanicline	2	Completed	2
DB00758	Clopidogrel	2	Active Not Recruiting	1
DB00843	Donepezil	2	Completed	1
DB00983	Formoterol	2	Withdrawn	1
DB00502	Haloperidol	2	Completed	1
DB01221	Ketamine	2	Completed	1
DB00480	Lenalidomide	2	Recruiting	1
DB00166	Lipoic acid	2	Completed	1
DB00422	Methylphenidate	2	Completed	1
DB14158	Microcrystalline cellulose	2	Completed	1
DB00635	Prednisone	2	Withdrawn	1
DB00818	Propofol	2	Completed	1
DB11664	Psilocybin	2	Recruiting	1
DB00980	Ramelteon	2	Completed	1
DB00140	Riboflavin	2	Completed	1
DB01037	Selegiline	2	Completed	2
DB00246	Ziprasidone	2	Completed	1
DB01043	Memantine	2 / 3	Completed	1
DB00112	Bevacizumab	3	Completed	1
DB00843	Donepezil	3	Completed	1
DB00843	Donepezil	3	Terminated	2
DB09149	Florbetapir (18F)	3	Unknown Status	1
DB00674	Galantamine	3	Completed	1
DB14522	Hydroxide ion	3	Completed	1
DB11075	Hypromellose	3	Completed	1
DB04335	Inosine	3	Completed	1
DB01221	Ketamine	3	Recruiting	1
DB01206	Lomustine	3	Completed	1
DB09415	Meglumine	3	Completed	1
DB00683	Midazolam	3	Recruiting	1
DB02701	Nicotinamide	3	Completed	1
DB11061	Povidone	3	Completed	1
DB00140	Riboflavin	3	Completed	1
DB00989	Rivastigmine	3	Completed	1
DB11756	Solanezumab	3	Completed	1
DB00139	Succinic acid	3	Completed	1
DB01238	Aripiprazole	4	Recruiting	1
DB00297	Bupivacaine	4	Recruiting	1
DB14726	Dabigatran	4	Completed	1
DB00633	Dexmedetomidine	4	Completed	2
DB00633	Dexmedetomidine	4	Recruiting	1
DB00843	Donepezil	4	Completed	2
DB00813	Fentanyl	4	Recruiting	1
DB01381	Ginkgo biloba	4	Completed	1
DB01221	Ketamine	4	Unknown Status	1
DB00818	Propofol	4	Completed	1
DB00818	Propofol	4	Unknown Status	2
DB01236	Sevoflurane	4	Completed	1
DB01236	Sevoflurane	4	Unknown Status	1
DB00682	Warfarin	4	Completed	1
DB00673	Aprepitant	Not Available	Unknown Status	1
DB01189	Desflurane	Not Available	Completed	1
DB01234	Dexamethasone	Not Available	Completed	1
DB00633	Dexmedetomidine	Not Available	Completed	1
DB00254	Doxycycline	Not Available	Completed	1
DB00187	Esmolol	Not Available	Completed	1
DB00783	Estradiol	Not Available	Terminated	1
DB09149	Florbetapir (18F)	Not Available	Completed	1
DB01381	Ginkgo biloba	Not Available	Completed	1
DB01221	Ketamine	Not Available	Completed	1
DB01002	Levobupivacaine	Not Available	Completed	1
DB00745	Modafinil	Not Available	Completed	1
DB00727	Nitroglycerin	Not Available	Completed	1
DB00008	Peginterferon alfa-2a	Not Available	Completed	1
DB00981	Physostigmine	Not Available	Unknown Status	1
DB00818	Propofol	Not Available	Completed	2
DB00818	Propofol	Not Available	Terminated	1
DB00811	Ribavirin	Not Available	Completed	1
DB06140	SUVN-502	Not Available	No Longer Available	1
DB01037	Selegiline	Not Available	Completed	1
DB00624	Testosterone	Not Available	Terminated	1
DB00759	Tetracycline	Not Available	Completed	1
DB11176	Zeaxanthin	Not Available	Completed	1