Hypercalcemia of Malignancy (DBCOND0028695)

Identifiers

Synonyms
Hypercalcaemia of malignancy / Cancer related hypercalcemia / Cancer-related hypercalcemia / Hypercalcemia of malignancy / Paraneoplastic hypercalcemia / Paraneoplastic hypercalcaemia / Humoral hypercalcemia of malignancy (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Betamethasone
A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
Clodronic acid
A bisphosphonate used to treat osteoporosis in postmenopausal women, hypercalcemia of malignancy, and osteolysis.
Cortisone acetate
A steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
Hydrocortisone
A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
Ibandronate
A bisphosphonate used to treat osteoporosis in postmenopausal women.
Methylprednisolone
A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
Methylprednisolone hemisuccinate
A water soluble corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
Pamidronic acid
A bisphosphonate used to treat Paget's disease, to treat hypercalcemia of malignancy, and to treat osteolytic bone lesions.
Prednisolone
A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
Prednisone
A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
Risedronic acid
A bisphosphonate used to treat osteoporosis and Paget's disease.
Zoledronic acid
A bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00003884
Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bonesupportive_care3completed
NCT00896454
Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calciumtreatment2completed
NCT00326820
Ibandronate or Zoledronate in Treating Patients With Newly Diagnosed Bone Metastases From Breast Cancertreatment3unknown_status
NCT01333267
One Week Comparison Study of PTH and PTHrP InfusionsNot Available1withdrawn
NCT00060138
Monoclonal Antibody Compared With Zoledronate in Treating Women With Breast Cancer and Bone Metastasessupportive_care1 / 2completed
NCT00458796
Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bonesupportive_careNot Availableterminated
NCT00301886
S0308 Zoledronate or Ibandronate in Preventing Bone Problems in Women With Stage IV Breast Cancer That Has Spread to the Bonesupportive_care3withdrawn
NCT04198480
A Clinical Trial to Assess the Efficacy and Safety of JMT103 in Patients With Refractory HCMtreatment1 / 2unknown_status