Mesothelioma (DBCOND0017375)

Identifiers

Synonyms
Mesotheliomas / Mesothelioma, unspecified / Mesothelioma, Malignant / Mesothelioma (malignant, clinical disorder) (disorder) / Mesothelioma malignant NOS / Mesothelioma malignant / Mesothelioma, malignant (morphologic abnormality)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Gemcitabine
A nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer.
Mitomycin
An antimetabolite used as an adjunct to ab externo (outside approach) eye surgeries for the treatment of glaucoma and used as a chemotherapeutic agent for various malignancies.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05571839
A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid TumorsNo drug interventionstreatment1recruiting
NCT06034860
Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Typestreatment1active_not_recruiting
NCT06057935
A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesotheliomatreatment2recruiting
NCT06638931
Agnostic Therapy in Rare Solid TumorsNo drug interventionstreatment2recruiting
NCT05215574
Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumorstreatment1active_not_recruiting
NCT05579366
PRO1184 for Advanced Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT05960773
Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesotheliomatreatment2recruiting
NCT06581549
Immune Microenvironment and Gene Expression Profiling in MesotheliomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT01851395
Rapid Autopsy and Procurement of Cancer TissueNo drug interventionsNot AvailableNot Availablerecruiting
NCT01950572
Tissue Procurement and Natural History Study of Patients With Malignant MesotheliomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT02875548
A Study to Assess the Long-term Safety of Tazemetostattreatment1 / 2enrolling_by_invitation
NCT03830229
Long Term Follow-up of Mesothelioma Patients and Their Family Members With Germline Mutations in BAP1 and Other GenesNo drug interventionsNot AvailableNot Availablerecruiting
NCT04242199
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid TumorsNo drug interventionstreatment1active_not_recruiting
NCT04431024
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition SyndromeNo drug interventionsNot AvailableNot Availablerecruiting
NCT04857372
A Phase I Study of IAG933 in Patients With Advanced Mesothelioma and Other Solid TumorsNo drug interventionstreatment1recruiting
NCT04913337
Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignanciestreatment1 / 2active_not_recruiting
NCT05005429
Study of the Efficacy and Safety of the Bintrafusp Alfa in Previously Treated Advanced Malignant Pleural Mesotheliomatreatment2completed
NCT06444815
A Study of VET3-TGI in Patients With Solid Tumorstreatment1recruiting
NCT04450043
The Transitions Project: Supporting Adults During the Shift From Cancer Treatment to SurveillanceNo drug interventionssupportive_careNot Availableunknown_status
NCT00295503
Cisplatin, Pemetrexed and Bevacizumab for Untreated Malignant Mesotheliomatreatment2completed
NCT01997190
Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusiontreatment1completed
NCT00188890
Early Diagnosis of Lung Cancer and Mesothelioma in Prior Asbestos WorkersNo drug interventionsNot AvailableNot Availablecompleted
NCT01362790
SS1P and Pentostatin Plus Cyclophosphamide for Mesotheliomatreatment1 / 2completed
NCT01119664
Combination Gene Transfer and ChemotherapyNo drug interventionstreatment1completed
NCT03655821
Dose Individualization of Pemetrexed - IMPROVE-IItreatment4terminated
NCT00128102
Suberoylanilide Hydroxamic Acid (Vorinostat, MK-0683) Versus Placebo in Advanced Malignant Pleural Mesothelioma (MK-0683-014)treatment3completed
NCT06491784
EXTRA-Meso (EXercise TheRApy in Mesothelioma) FeasibilityNo drug interventionsotherNot Availablerecruiting
NCT00629343
Phase I Dose-Escalation Study Of Azacitidine In Combination With Temozolomidetreatment1unknown_status
NCT02758587
Study of FAK (Defactinib) and PD-1 (Pembrolizumab) Inhibition in Advanced Solid Malignancies (FAK-PD1)treatment1 / 2unknown_status
NCT06466187
A Study of SGN-MesoC2 in Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT00423254
Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.No drug interventionstreatment1completed
NCT04115254
Stereotactic Magnetic Resonance Guided Radiation TherapyNo drug interventionstreatmentNot Availablesuspended
NCT03652077
A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignanciestreatment1completed
NCT00061477
Pemetrexed Plus Gemcitabine as Front-Line Chemotherapy for Patients With Malignant Pleural or Peritoneal Mesotheliomatreatment2completed
NCT05070247
A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumorstreatment1 / 2recruiting
NCT01912547
Thromboelastography During Surgery for Malignant Pleural MesotheliomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT02838745
Study of Cytoreductive Surgery and Hyperthermic Intraoperative Chemotherapy With Pemetrexed and Cisplatin for MPMother1terminated
NCT01604005
PIT: Prophylactic Irradiation of Tracts in Patients With Malignant Pleural MesotheliomaNo drug interventionsprevention3terminated
NCT02029105
Serum Biomarkers in Diagnosis of MesotheliomaNot AvailableNot Availablecompleted
NCT02293005
Phase II Trial of Alisertib (MLN8237) in Salvage Malignant Mesotheliomatreatment2completed
NCT00101283
Pemetrexed Plus Gemcitabine or Carboplatin for Patients With Advanced Malignant Pleural Mesotheliomatreatment2completed
NCT05238883
A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumorstreatment1recruiting
NCT03538028
A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignanciestreatment1completed
NCT00715611
Pleurectomy/Decortication (Neo) Adjuvant Chemotherapy and Intensity Modulated Radiation Therapy to the Pleura in Patients With Locally Advanced Malignant Pleural Mesotheliomatreatment2active_not_recruiting
NCT03935893
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancerstreatment2recruiting
NCT02784171
Pembrolizumab in Patients With Advanced Malignant Pleural Mesotheliomatreatment2 / 3active_not_recruiting
NCT03881488
Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignanciestreatment1active_not_recruiting
NCT00651456
Mesothelioma Avastin Plus Pemetrexed-cisplatin Studytreatment2 / 3completed
NCT00748085
CryoSpray Ablation(tm)in Malignant Airway Disease to Determine Safety, and Tissue Effect in the Lung (ICE the MAD)No drug interventionstreatmentNot Availableterminated
NCT04537715
Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levelstreatment1completed
NCT04840615
Intratumor Injection of Anti-Mesothelin Immunotoxin LMB-100 With Ipilimumab in Malignant Mesotheliomatreatment1terminated
NCT04214015
A Pilot Study to Explore the Role of Gut Flora in Metastatic MesotheliomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04940637
UNITO-001- Study in HRR/PDL1 Positive MPM/NSCLCtreatment2recruiting
NCT02611037
Transarterial Chemoperfusion: Cisplatin, Methotrexate, Gemcitabine for Unresectable Pleural Mesotheliomatreatment2active_not_recruiting
NCT03436732
Mesothelin-Targeted Immunotoxin LMB-100 in Combination With SEL-110 in Subjects With Malignant Pleural or Peritoneal Mesotheliomatreatment1terminated
NCT03918252
Neoadjuvant Immune Checkpoint Blockade in Resectable Malignant Pleural Mesotheliomatreatment2active_not_recruiting
NCT03907852
Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancertreatment1 / 2active_not_recruiting
NCT02511600
Comparison of Progel Sealant to Standard of Care (SOC) for Patients Undergoing DecorticationNo drug interventionstreatment3withdrawn
NCT01281800
Cisplatin With Alimta or Gemcitabine in Long Infusion for MesotheliomaNo drug interventionstreatment2unknown_status
NCT02073500
Peritoneal Surface Malignancies - Characterization, Models and Treatment StrategiesNo drug interventionsNot AvailableNot Availablerecruiting
NCT05245500
Phase 1/2 Study of MRTX1719 in Solid Tumors With MTAP Deletiontreatment1 / 2recruiting
NCT02661100
A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patientstreatment1 / 2withdrawn
NCT00407459
Phase II Study of Bevacizumab, Pemetrexed and Carboplatin as First-Line Therapy in Malignant Pleural Mesotheliomatreatment2completed
NCT00794859
Sorafenib in Previously Treated Malignant Mesotheliomatreatment2unknown_status
NCT00668499
A Study of VEGF-Antisense Oligonucleotide in Combination With Pemetrexed and Cisplatin for the Treatment of Advanced Malignant Mesotheliomatreatment1 / 2withdrawn
NCT02613299
Surgery for Mesothelioma After Radiation Therapy "SMART" for Resectable Malignant Pleural MesotheliomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT03638206
Autologous CAR-T/TCR-T Cell Immunotherapy for MalignanciesNo drug interventionstreatment1 / 2unknown_status
NCT02798536
Mesothelin-Targeted Immunotoxin LMB-100 in People With Malignant Mesotheliomatreatment1completed
NCT04515836
Olaparib in Patients With HRD Malignant Mesotheliomatreatment2recruiting
NCT03023319
Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumorstreatment1completed
NCT02611024
Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumorstreatment1 / 2recruiting
NCT02648763
Staging Procedures to Diagnose Malignant Pleural MesotheliomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT04792463
Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition SyndromeNo drug interventionsNot AvailableNot Availablerecruiting
NCT02860286
Study of the EZH2 Inhibitor Tazemetostat in Malignant Mesotheliomatreatment2completed
NCT01188486
Pulmonary Interstitial Lymphography in Early Stage Lung Cancerdevice_feasibilityNot Availableterminated
NCT01385722
Molecular Analysis of Thoracic MalignanciesNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT05404022
Feasibility Trial of a Personalised Nutrition and Activity Programme for People With Lung Cancer Over 65 YearsNo drug interventionstreatmentNot Availablecompleted
NCT00040625
ALIMTA (Pemetrexed) Alone or in Combination With Cisplatin for Patients With Malignant Mesothelioma.Not AvailableNot Availableapproved_for_marketing
NCT05461430
Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)No drug interventionsNot AvailableNot Availablerecruiting
NCT00895648
Pemetrexed (ALIMTA) Plus Cisplatin Followed by Surgery and Radiation Therapy for Mesotheliomatreatment2terminated
NCT04985357
Defining the Clinical Potential of Mass Response as a Biomarker for Patient Tumor Sensitivity to DrugsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02688166
Cardiac MRI Biomarker Testing (GCC 1618)No drug interventionsNot AvailableNot Availableterminated
NCT04040231
Using a Targeted Cancer Vaccine (Galinpepimut-S) With Immunotherapy (Nivolumab) in Mesotheliomatreatment1active_not_recruiting
NCT05627960
First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor MalignanciesNo drug interventionstreatment1recruiting
NCT06452160
A Study of BGC515 Capsules in Subjects With Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT06196294
GPC3/Mesothelin-CAR-γδT Cells Against Cancerstreatment1recruiting
NCT00190762
A Study Comparing Pemetrexed Plus Best Supportive Care Versus Best Supportive Care Alone in the Treatment of Mesotheliomatreatment3completed
NCT03683680
Prospectively Collected Pleural Biopsies for Validation of Malignant Pleural Mesothelioma Prognostic BiomarkersNo drug interventionsdiagnosticNot Availablerecruiting
NCT01445392
SS1(dsFV)PE38 Plus Pemetrexed and Cisplatin to Treat Malignant Pleural Mesotheliomatreatment1terminated
NCT04300244
Nivolumab and Ipilimumab +/- UV1 Vaccination as Second Line Treatment in Patients With Malignant Mesotheliomatreatment2active_not_recruiting
NCT02610140
Phase II Anetumab Ravtansine as 2nd Line Treatment for Malignant Pleural Mesothelioma (MPM)treatment2completed
NCT02628067
Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)treatment2recruiting
NCT04375267
177Lu-DOTA-TATE and Olaparib in Somatostatin Receptor Positive Tumourstreatment1active_not_recruiting
NCT04429204
Cryoablation for the Promotion of Local Tumor Infiltration in Patients With MesotheliomaNo drug interventionstreatmentNot Availablewithdrawn
NCT02139904
Vinorelbine in Mesotheliomatreatment2completed
NCT00685204
An Efficacy Study of Milataxel (TL139) Administered Orally for Malignant Mesotheliomatreatment2unknown_status
NCT02040272
Mesothelioma and Radical Surgery 2No drug interventionstreatmentNot Availableunknown_status
NCT02716272
Nivolumab Monotherapy or Nivolumab Plus Ipilimumab, for Unresectable Malignant Pleural Mesothelioma (MPM) Patientstreatment2completed
NCT01590472
Do Your Genes Put You at a Higher Risk of Developing MesotheliomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00859469
Eloxatin® Plus Gemcitabine Chemotherapy for Mesotheliomatreatment2completed
NCT02385812
Screening of Alberta Asbestos Exposed Workers for Lung Cancer and MesotheliomaNo drug interventionsscreening2terminated
NCT02709512
Ph 2/3 Study in Subjects With MPM to Assess ADI-PEG 20 With Pemetrexed and Cisplatintreatment2 / 3completed
NCT00787410
An Open-label, Phase II Trial of ZD1839 (IRESSA) in Patients With Malignant Mesotheliomatreatment2completed
NCT05228795
Glypican-1 Expression in Epithelioid Mesothelioma, Adenocarcinoma and SCC of the LungNo drug interventionsNot AvailableNot Availableunknown_status
NCT02899195
Phase II MEDI4736 in Combination With Chemotherapy for First-Line Treatment of Unresectable Mesotheliomatreatment2completed
NCT06051695
A Study to Evaluate the Safety and Efficacy of A2B694, a Logic-gated CAR T, in Subjects With Solid Tumors That Express MSLN and Have Lost HLA-A*02 ExpressionNo drug interventionstreatment1 / 2recruiting
NCT02903914
Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumorstreatment1 / 2completed
NCT03644550
Anti-Mesothelin Immunotoxin LMB-100 Followed by Pembrolizumab in Malignant Mesotheliomatreatment2terminated
NCT01204203
Pilot Study of Bisphosphonate Therapy (Zoledronic Acid) in Patients With Malignant Mesothelioma (UAB 0901)treatment2completed
NCT01624090
Mithramycin for Lung, Esophagus, and Other Chest Cancerstreatment2terminated
NCT04028479
The Registry of Oncology Outcomes Associated With Testing and TreatmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT02395679
Dendritic Cells Loaded With Allogeneous Cell Lysate in Mesothelioma PatientsNo drug interventionstreatment1unknown_status
NCT06536179
New Preclinical and Clinical Approaches to MesotheliomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT03983954
Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumorstreatment1active_not_recruiting
NCT01413451
Amatuximab for High Mesothelin Cancerstreatment0terminated
NCT01356251
Psychosocial Needs and Exploration of Online Support for Patients With MesotheliomaNo drug interventionssupportive_careNot Availablecompleted
NCT02592551
MEDI4736 Or MEDI4736 + Tremelimumab In Surgically Resectable Malignant Pleural Mesotheliomaother2completed
NCT00535951
Pharmacokinetic, Safety, and Efficacy Effects of Oral LBH589 on Dextromethorphan in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer or Malignant Pleural Mesotheliomatreatment1completed
NCT06010277
Folinic Acid for Prevention of Pemetrexed-induced Toxicityprevention4recruiting
NCT00004547
Treatment of Peritoneal Cancer With Surgery, Perfused Heated Cisplatin and Chemotherapytreatment2completed
NCT03207347
A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001)treatment2completed
NCT05415098
Study of Safety, Pharmacokinetic and Efficacy of APG-5918 in Advanced Solid Tumors or LymphomasNo drug interventionstreatment1recruiting
NCT02748798
Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disordersdiagnostic0recruiting
NCT02958683
Chest Wall Motion Analysis in DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00604461
Carboplatin, Bevacizumab and Pemetrexed in the First-Line Treatment of Patients With Malignant Pleural Mesothelioma (MPM)treatment1 / 2terminated
NCT03556228
Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphomatreatment1recruiting
NCT04301011
Study of TBio-6517 Given Alone or in Combination With Pembrolizumab in Solid Tumorstreatment1 / 2terminated
NCT06310993
Exercise to Boost Immunity in Advanced CancerNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00094978
Depsipeptide/Flavopiridol Infusion for Cancers of the Lungs, Esophagus, Pleura, Thymus or Mediastinumtreatment1terminated
NCT03867578
Magnetic Resonance Imaging for Detection of Peritoneal MesotheliomaNo drug interventionsscreeningNot Availablecompleted
NCT03517488
A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumorstreatment1completed
NCT01401907
Early Palliative Care in Advanced Lung and Gastrointestinal MalignanciesNo drug interventionssupportive_careNot Availablecompleted
NCT01776385
The ISET (Isolation by Size of Epithelial Tumor Cells) and the CellSearch Methods in Malignant Pleural MesotheliomaNo drug interventionspreventionNot Availablecompleted
NCT00996385
Velcade and Eloxatin for Patients With Malignant Pleural or Peritoneal Mesotheliomatreatment2unknown_status
NCT02859415
Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms With Pleuropulmonary Metastasestreatment1 / 2terminated
NCT03319537
Pevonedistat Alone and in Combination With Chemotherapy in Patients With Mesotheliomatreatment1 / 2terminated
NCT02062632
Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapysupportive_care2terminated
NCT00551252
A Phase II Study of the Association of Glivec® Plus Gemzar® in Patients With Unresectable, Refractory, Malignant Mesotheliomatreatment2unknown_status
NCT02078700
Feasibility of an Early Palliative Care Intervention for Metastatic Cancer Patients. A Phase 2 Study.No drug interventionssupportive_care2completed
NCT01907100
Nintedanib (BIBF 1120) in Mesotheliomatreatment2 / 3terminated
NCT04334759
DuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural Mesotheliomatreatment3active_not_recruiting
NCT05278975
Study of RSO-021 in Patients With Malignant Pleural Effusion Due to Advanced/Metastatic Solid Tumors Including Mesotheliomatreatment1 / 2recruiting
NCT04028570
A Feasibility Study Evaluating Surgery for Mesothelioma After Radiation Therapy Using Extensive Pleural ResectionNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05932199
Neoadjuvant Durvalumab and Tremelimumab With and Without Chemotherapy for Mesotheliomatreatment1 / 2recruiting
NCT02899299
Study of Nivolumab Combined With Ipilimumab Versus Pemetrexed and Cisplatin or Carboplatin as First Line Therapy in Unresectable Pleural Mesothelioma Patientstreatment3completed
NCT02012699
Integrated Cancer Repository for Cancer ResearchNo drug interventionsNot AvailableNot Availablerecruiting
NCT04665206
Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors Enriched for Tumors With NF2 or mNF2 Gene MutationsNo drug interventionstreatment1 / 2recruiting
NCT05451849
A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancertreatment1 / 2active_not_recruiting
NCT03656549
Dose Individualization of Pemetrexed - IMPROVE-Itreatment2completed
NCT01135849
B-Receptor Signaling in CardiomyopathyNo drug interventionsNot AvailableNot Availablecompleted
NCT02948413
Influence of Psychosocial Distress and Lifetime Trauma Exposure on Traumatic Stress Among Oncology Patients on Clinical TrialsNo drug interventionsNot AvailableNot Availablecompleted
NCT04234113
Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumorstreatment1active_not_recruiting
NCT05311618
Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumorstreatment1active_not_recruiting
NCT06090318
Milademetan in Combination With Atezolizumab in Patients With Advanced Solid Tumors With CDKN2A Losstreatment1 / 2withdrawn
NCT06477419
A Study of Sacituzumab Govitecan in People With Mesotheliomatreatment2recruiting
NCT01569919
A Phase II Trial to Assess TroVax® Plus Chemotherapy in Patients With Malignant Pleural Mesotheliomatreatment2unknown_status
NCT00454519
Surgery Plus Intraoperative Peritoneal Hyperthermic Chemotherapy (IPHC) to Treat Peritoneal CarcinomatosisNo drug interventionstreatment2unknown_status
NCT04981119
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell ManufacturingNo drug interventionsNot AvailableNot Availablerecruiting
NCT03655834
Dose Individualization of Pemetrexed - IMPROVE-IIIdiagnostic4completed
NCT04272034
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid TumorsNo drug interventionstreatment1active_not_recruiting
NCT00637624
N-AcetylCysteine vs. Placebo to Prevent Neurotoxicity Induced by Platinum Containing ChemotherapypreventionNot Availableterminated
NCT00597116
An Efficacy and Safety Study With Vandetanib to Treat Inoperable or Relapsed Malignant Mesotheliomatreatment2terminated
NCT05730816
MAGIC AKI: Magnesium for the Prevention of HIOC-Associated AKIprevention2recruiting
NCT00469196
Tomotherapy Treatment for MesotheliomaNo drug interventionstreatment2completed
NCT02628535
Safety Study of MGD009 in B7-H3-expressing TumorsNo drug interventionstreatment1terminated
NCT04088786
Phase I Trial HIPEC With Nal-irinotecantreatment1completed
NCT01583686
CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic Cancertreatment1 / 2terminated
NCT00785239
CryoSpray Ablation(tm)Thoracic Patient RegistryNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00316225
Study of Pemetrexed in Mesothelioma and Lung Cancer Patients With Fluid Around the Lungs or Abdomentreatment2completed
NCT01521325
A Single-Dose Pilot Study of Radiolabeled Amatuximab (MORAb-009) in Mesothelin Over Expressing Cancersbasic_science1completed
NCT00137826
Bevacizumab (Avastin) and Erlotinib (Tarceva) in Previously Treated Mesotheliomatreatment2completed
NCT02467426
Isolated Thoracic Perfusion (ITP-F) for MPMNot AvailableNot Availablecompleted
NCT04056026
A Single Dose FMT Infusion as an Adjunct to Keytruda for Metastatic Mesotheliomatreatment0completed
NCT00402766
Cisplatin, Pemetrexed, and Imatinib Mesylate in Malignant Mesotheliomatreatment1completed
NCT04153565
A Study of Pembrolizumab in Combination With Cisplatin and Pemetrexed in Advanced Malignant Pleural Mesothelioma (MPM) (MK-3475-A17)treatment1completed
NCT04631731
Risk Factors of Immune-ChEckpoint Inhibitors MEdiated Liver, Gastrointestinal, Endocrine and Skin ToxicityNo drug interventionsdiagnostic1 / 2recruiting
NCT03560973
A Double Blind, Placebo Controlled, Randomized Phase II Study Evaluating Gemcitabine With or Without Ramucirumab , for II Line Treatment MPMtreatment2unknown_status
NCT03075527
A Phase 2 Study of Durvalumab in Combination With Tremelimumab in Malignant Pleural Mesotheliomatreatment2suspended
NCT04802876
Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumorstreatment2recruiting
NCT06538376
Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICUNo drug interventionsdiagnosticNot Availablerecruiting
NCT03610360
DENdritic Cell Immunotherapy for MesotheliomaNo drug interventionstreatment2 / 3completed
NCT00325494
A Study of MORAb-009 in Subjects With Pancreatic Cancer, Mesothelioma, or Certain Types of Ovarian or Lung Cancertreatment1completed
NCT03685591
PF-06952229 Treatment in Adult Patients With Advanced Solid Tumorstreatment1terminated
NCT02071862
Study of the Glutaminase Inhibitor CB-839 in Solid Tumorstreatment1completed
NCT04489862
αPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid TumorsNo drug interventionstreatment0unknown_status
NCT05041062
A Study of Immunotherapy Drugs Nivolumab and Ipilimumab in Patients w/Resectable Malignant Peritoneal Mesotheliomatreatment2completed
NCT05819580
Studying the Clinical Trial Experiences of Patients With MesotheliomaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05544929
A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancerstreatment1recruiting
NCT04316689
First-in-human Study of S-588210 (S-488210+S-488211)No drug interventionstreatment1completed
NCT03531840
Olaparib in People With Malignant Mesotheliomatreatment2completed
NCT02464904
Intrapleural Cryotherapy for Malignant Pleural MesotheliomaNo drug interventionstreatmentNot Availableterminated
NCT04481672
Intravenous Magnesium in Patients Receiving Cisplatinsupportive_care1completed
NCT01719068
Early Detection of Lung Cancer and Mesothelioma in Workers Exposed to AsbestosNo drug interventionsNot AvailableNot Availableunknown_status
NCT02414269
Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelintreatment1 / 2active_not_recruiting
NCT01134146
Radical Pleurectomy/Decortication (PD) and Intensity Modulated Radiotherapy (IMRT)No drug interventionstreatment1completed
NCT02613312
Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural MesotheliomaNo drug interventionsNot AvailableNot Availableterminated
NCT04804410
Dielectric Properties of Matched Tissue Samples From Thoracic Malignancies and Corresponding Normal TissuesNo drug interventionstreatmentNot Availableunknown_status
NCT01627795
Safety and Efficacy of Oshadi D and Oshadi R for Malignant Mesothelioma TreatmentNo drug interventionstreatment1 / 2suspended
NCT03063450
CheckpOiNt Blockade For Inhibition of Relapsed Mesotheliomatreatment3active_not_recruiting
NCT00703638
Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumorstreatment1completed
NCT04345705
Direct Injection of Poly-ICLC (Hiltonol®) Vaccine In Malignant Pleural Mesotheliomatreatment1not_yet_recruiting
NCT02349958
Clinical Trial of Intraperitoneal Hyperthermic ChemotherapyNo drug interventionstreatment2unknown_status