Peripheral alpha-1 blockers
- Peripheral alpha-1 blockers
- Accession Number
This category contains drugs that block the peripheral alpha-1 receptors selectively and non-selectively. This blockade may cause antihypertensive effects. Some of these drugs may also have beta-blocking effects.
Drug Drug Description Doxazosin An alpha-1 adrenergic receptor used to treat mild to moderate hypertension and urinary obstruction due to benign prostatic hyperplasia. Prazosin An alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension. Terazosin An alpha-1 adrenergic antagonist used in the treatment of symptomatic benign prostatic hyperplasia and management of hypertension. Alfuzosin An alpha-1 adrenergic antagonist used in the management of benign prostatic hypertrophy (BPH). Tamsulosin An alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction. Silodosin An alpha-1 adrenergic receptor antagonist used to treat symptoms associated with benign prostatic hyperplasia (BPH). Phenoxybenzamine An alpha adrenergic agonist used to treat pheochromocytoma and episodes of hypertension and sweating. Phentolamine An alpha adrenergic antagonist used to reverse soft tissue anesthesia. Tolazoline A vasodilator used to treat pulmonary artery anomalies. Trazodone A serotonin uptake inhibitor used to treat major depressive disorder. Bunazosin Bunazosin has been used in trials studying the treatment of High Blood Pressure. Labetalol An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. Trimazosin Trimazosin is a sympatholytic alpha blocker. Indoramin Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action. Urapidil Urapidil has been investigated for the treatment of Hypertension During Pre-Eclampsia.
- Drugs & Drug Targets