BMI >27 kg/m2

Also known as: Over-weight / Over Weight / Overweight / Overweight (finding) / Excessive body weight gain (finding) [Ambiguous]

DrugDrug NameDrug Description
DB00704NaltrexoneA narcotic antagonist used in opioid overdose.
DB01083OrlistatA reversible inhibitor of gastrointestinal lipases indicated for weight loss and weight maintenance.
DB00191PhentermineA sympathomimetic anorectic agent used as a short-term adjunct therapy that is included in a regimen of weight reduction in cases of exogenous obesity.
DB00273TopiramateAn anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines.
DrugDrug NameTargetType
DB00704NaltrexoneMu-type opioid receptortarget
DB00704NaltrexoneKappa-type opioid receptortarget
DB00704NaltrexoneDelta-type opioid receptortarget
DB00704NaltrexoneHCG20471, isoform CRA_ctarget
DB00704NaltrexoneUDP-glucuronosyltransferase 1-1enzyme
DB01083OrlistatPancreatic triacylglycerol lipasetarget
DB01083OrlistatFatty acid synthasetarget
DB01083OrlistatGastric triacylglycerol lipasetarget
DB01083OrlistatCytochrome P450 3A4enzyme
DB01083OrlistatCytosolic phospholipase A2enzyme
DB01083OrlistatSerum albumincarrier
DB01083OrlistatPancreatic triacylglycerol lipaseenzyme
DB01083OrlistatGastric triacylglycerol lipaseenzyme
DB01083OrlistatFatty acid synthaseenzyme
DB00191PhentermineSodium-dependent noradrenaline transportertarget
DB00191PhentermineSodium-dependent dopamine transportertarget
DB00191PhentermineAmine oxidase [flavin-containing] Atarget
DB00191PhentermineAmine oxidase [flavin-containing] Btarget
DB00191PhentermineSodium-dependent serotonin transportertarget
DB00191PhenterminePro-neuropeptide Ytarget
DB00191PhentermineCytochrome P450 3A4enzyme
DB00273TopiramateGamma-aminobutyric acid receptor subunit alpha-1target
DB00273TopiramateVoltage-gated sodium channel alpha subunittarget
DB00273TopiramateCarbonic anhydrase 2target
DB00273TopiramateCarbonic anhydrase 4target
DB00273TopiramateKainate receptorstarget
DB00273TopiramateCytochrome P450 2C19enzyme
DB00273TopiramateCytochrome P450 3A4enzyme
DB00273TopiramateCarbonic anhydrase 1target
DB00273TopiramateCarbonic anhydrase 3target
DB00273TopiramateVoltage gated L-type calcium channeltarget
DB00273TopiramateVoltage-dependent R-type calcium channeltarget
DB00273TopiramateSerum albumincarrier
DB00273TopiramateP-glycoprotein 1transporter
DB00273Topiramate5'-AMP-activated protein kinasetransporter
DrugDrug NamePhaseStatusCount
DB15167Fallypride0Recruiting1
DB14522Hydroxide ion0Not Yet Recruiting1
DB12518Raclopride0Recruiting1
DB00669Sumatriptan0Not Yet Recruiting1
DB14949AZD-76871Completed1
DB00316Acetaminophen1Completed2
DB06698Betahistine1Completed1
DB06655Liraglutide1Recruiting1
DB00331Metformin1Unknown Status1
DB11062Octisalate1Recruiting1
DB09535Octocrylene1Recruiting1
DB01083Orlistat1Completed1
DB14887PF-046201101Completed2
DB01132Pioglitazone1Completed1
DB13928Semaglutide1Completed5
DB13928Semaglutide1Recruiting1
DB13928Semaglutide1Terminated1
DB11700Setmelanotide1Completed1
DB15171Tirzepatide1Completed1
DB15171Tirzepatide1Recruiting1
DB01586Ursodeoxycholic acid1Unknown Status1
DB09321Zinc oxide1Recruiting1
DB00331Metformin1 / 2Recruiting1
DB09046Metreleptin1 / 2Completed1
DB11700Setmelanotide1 / 2Completed1
DB12671Beloranib2Completed2
DB01156Bupropion2Completed1
DB00608Chloroquine2Active Not Recruiting1
DB14956Davalintide2Completed1
DB11994Diacerein2Completed1
DB01276Exenatide2Completed1
DB01039Fenofibrate2Terminated1
DB15048Licogliflozin2Completed1
DB06655Liraglutide2Completed1
DB09046Metreleptin2Completed2
DB00704Naltrexone2Completed1
DB14016Ox bile extract2Completed1
DB00191Phentermine2Completed1
DB01278Pramlintide2Completed4
DB11700Setmelanotide2Completed1
DB01105Sibutramine2Completed2
DB12414Usistapide2Completed2
DB00159Icosapent2 / 3Active Not Recruiting1
DB11062Octisalate2 / 3Completed1
DB09535Octocrylene2 / 3Completed1
DB11133Omega-3 fatty acids2 / 3Active Not Recruiting1
DB14151Phosphorus2 / 3Completed1
DB01399Salsalate2 / 3Completed1
DB09321Zinc oxide2 / 3Completed1
DB09026Aliskiren3Completed1
DB00437Allopurinol3Completed1
DB06413Armodafinil3Completed1
DB01156Bupropion3Completed4
DB01156Bupropion3Terminated1
DB00153Ergocalciferol3Completed1
DB13961Fish oil3Terminated1
DB06655Liraglutide3Completed1
DB06655Liraglutide3Recruiting1
DB04871Lorcaserin3Completed1
DB00678Losartan3Completed1
DB00331Metformin3Completed1
DB00704Naltrexone3Completed4
DB00704Naltrexone3Terminated1
DB01032Probenecid3Completed1
DB13928Semaglutide3Active Not Recruiting1
DB13928Semaglutide3Completed5
DB13928Semaglutide3Not Yet Recruiting1
DB13928Semaglutide3Recruiting2
DB15171Tirzepatide3Active Not Recruiting1
DB15171Tirzepatide3Not Yet Recruiting1
DB15171Tirzepatide3Recruiting3
DB11094Vitamin D3Completed1
DB01238Aripiprazole4Completed1
DB09495Avobenzone4Completed1
DB01373Calcium4Completed1
DB06724Calcium carbonate4Completed1
DB08907Canagliflozin4Completed1
DB00758Clopidogrel4Completed1
DB04839Cyproterone acetate4Recruiting1
DB09045Dulaglutide4Completed1
DB00977Ethinylestradiol4Recruiting1
DB01276Exenatide4Recruiting1
DB06655Liraglutide4Completed2
DB06655Liraglutide4Recruiting1
DB06655Liraglutide4Suspended1
DB06655Liraglutide4Terminated1
DB06655Liraglutide4Unknown Status1
DB06655Liraglutide4Withdrawn1
DB04871Lorcaserin4Completed1
DB04871Lorcaserin4Terminated1
DB00331Metformin4Completed1
DB00331Metformin4Recruiting1
DB00331Metformin4Terminated1
DB00331Metformin4Unknown Status1
DB01141Micafungin4Completed1
DB01252Mitiglinide4Unknown Status1
DB09242Moxonidine4Unknown Status1
DB11062Octisalate4Completed1
DB09535Octocrylene4Completed1
DB00275Olmesartan4Completed1
DB01083Orlistat4Completed1
DB13928Semaglutide4Completed1
DB11094Vitamin D4Completed1
DB00316AcetaminophenNot AvailableRecruiting1
DB01156BupropionNot AvailableCompleted1
DB00608ChloroquineNot AvailableCompleted1
DB00586DiclofenacNot AvailableCompleted1
DB06655LiraglutideNot AvailableCompleted2
DB06655LiraglutideNot AvailableEnrolling by Invitation1
DB06655LiraglutideNot AvailableRecruiting1
DB04871LorcaserinNot AvailableCompleted1
DB00704NaltrexoneNot AvailableCompleted1
DB00184NicotineNot AvailableCompleted1
DB01083OrlistatNot AvailableCompleted5
DB01083OrlistatNot AvailableWithdrawn1
DB00191PhentermineNot AvailableCompleted2
DB09528PhylloquinoneNot AvailableUnknown Status1