Alcohol Withdrawal Syndrome

Also known as: Alcohol Withdrawal Syndrome(AWS) / Alcohol Withdrawal / Alcohol withdrawal syndrome (disorder) / (Alcoholic psychosis: [Korsakov's] or [other]) or (withdrawal syndrome - alcohol)

DrugDrug NameDrug Description
DB00335AtenololA synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients.
DB00564CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
DB13835CaroverineA calcium channel blocker indicated in the treatment of smooth muscle spasms, alcohol and drug withdrawal, and tinnitus.
DB01563Chloral hydrateA mild hypnotic used for experimental purposes that was previously used for the treatment of insomnia.
DB00475ChlordiazepoxideA benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period.
DB00829DiazepamA long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures.
DB00186LorazepamA short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures.
DB00842OxazepamAn intermediate-acting benzodiazepine with slow onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawals, and insomnia.
DB01174PhenobarbitalA long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures.
DB09210PiracetamA nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer.
DrugDrug NameTargetType
DB00335AtenololBeta-1 adrenergic receptortarget
DB00335AtenololBeta-2 adrenergic receptortarget
DB00335AtenololCytochrome P450 2D6enzyme
DB00335AtenololBile salt export pumptransporter
DB00335AtenololSerum albumincarrier
DB00564CarbamazepineVoltage-gated sodium channel alpha subunittarget
DB00564CarbamazepineCytochrome P450 2C8enzyme
DB00564CarbamazepineCytochrome P450 2B6enzyme
DB00564CarbamazepineCytochrome P450 3A4enzyme
DB00564CarbamazepineCytochrome P450 1A2enzyme
DB00564CarbamazepineCytochrome P450 2C19enzyme
DB00564CarbamazepineCytochrome P450 2C9enzyme
DB00564CarbamazepineP-glycoprotein 1transporter
DB00564CarbamazepineCytochrome P450 3A5enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
DB00564CarbamazepineRalA-binding protein 1transporter
DB00564CarbamazepineCanalicular multispecific organic anion transporter 1transporter
DB00564CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
DB00564CarbamazepineNuclear receptor subfamily 1 group I member 2target
DB00564CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
DB13835CaroverineCytochrome P450 3A4enzyme
DB00475ChlordiazepoxideGABA(A) Receptortarget
DB00475ChlordiazepoxideGABA(A) Receptor Benzodiazepine Binding Sitetarget
DB00475ChlordiazepoxideCytochrome P450 3A4enzyme
DB00829DiazepamCytochrome P450 3A4enzyme
DB00829DiazepamSerum albumincarrier
DB00829DiazepamCytochrome P450 2C9enzyme
DB00829DiazepamCytochrome P450 2C19enzyme
DB00829DiazepamCytochrome P450 3A5enzyme
DB00829DiazepamCytochrome P450 3A7enzyme
DB00829DiazepamP-glycoprotein 1transporter
DB00829DiazepamCytochrome P450 2B6enzyme
DB00829DiazepamProstaglandin G/H synthase 1enzyme
DB00829DiazepamCytochrome P450 2C18enzyme
DB00829DiazepamCytochrome P450 2C8enzyme
DB00829DiazepamCytochrome P450 2E1enzyme
DB00829DiazepamGABA(A) Receptortarget
DB00829DiazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
DB00186LorazepamUDP-glucuronosyltransferase 2B15enzyme
DB00186LorazepamGABA(A) Receptortarget
DB00186LorazepamCytochrome P450 3A4enzyme
DB00186LorazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
DB00842OxazepamUDP-glucuronosyltransferase 2B15enzyme
DB00842OxazepamUDP-glucuronosyltransferase 2B7enzyme
DB00842OxazepamUDP-glucuronosyltransferase 1-9enzyme
DB00842OxazepamGABA(A) Receptortarget
DB00842OxazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
DB00842OxazepamSerum albumincarrier
DB01174PhenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01174PhenobarbitalCytochrome P450 2C19enzyme
DB01174PhenobarbitalCytochrome P450 2C9enzyme
DB01174PhenobarbitalCytochrome P450 2B6enzyme
DB01174PhenobarbitalCytochrome P450 2C8enzyme
DB01174PhenobarbitalCytochrome P450 1A2enzyme
DB01174PhenobarbitalCytochrome P450 3A4enzyme
DB01174PhenobarbitalCanalicular multispecific organic anion transporter 2transporter
DB01174PhenobarbitalBile salt export pumptransporter
DB01174PhenobarbitalP-glycoprotein 1transporter
DB01174PhenobarbitalMultidrug resistance-associated protein 1transporter
DB01174PhenobarbitalSolute carrier organic anion transporter family member 2A1transporter
DB01174PhenobarbitalCanalicular multispecific organic anion transporter 1transporter
DB01174PhenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01174PhenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01174PhenobarbitalGlutamate receptor 2target
DB01174PhenobarbitalGlutamate receptor ionotropic, kainate 2target
DB01174PhenobarbitalCytochrome P450 2A6enzyme
DB01174PhenobarbitalCytochrome P450 2E1enzyme
DB01174PhenobarbitalCytochrome P450 3A5enzyme
DB01174PhenobarbitalCytochrome P450 1A1enzyme
DB01174PhenobarbitalCytochrome P450 2C18enzyme
DB01174PhenobarbitalCytochrome P450 3A7enzyme
DB01174PhenobarbitalCytochrome P450 4B1enzyme
DB01174PhenobarbitalNMDA receptortarget
DB01174PhenobarbitalNuclear receptor subfamily 1 group I member 2target
DB01174PhenobarbitalUDP-glucuronosyltransferase 1-1enzyme
DB01174PhenobarbitalUDP-glucuronosyltransferase 2B7enzyme
DrugDrug NamePhaseStatusCount
DB09061Cannabidiol0Not Yet Recruiting1
DB00107Oxytocin1Completed1
DB00457Prazosin1 / 2Recruiting1
DB00181Baclofen2Terminated1
DB00996Gabapentin2Completed2
DB00186Lorazepam2Completed1
DB00107Oxytocin2Completed1
DB00140Riboflavin2Not Yet Recruiting1
DB00653Magnesium sulfate2 / 3Completed1
DB00152Thiamine2 / 3Completed1
DB00181Baclofen3Terminated1
DB00475Chlordiazepoxide3Completed1
DB01202Levetiracetam3Completed1
DB14513Magnesium3Recruiting1
DB00181Baclofen4Recruiting1
DB03568Butyric Acid4Completed1
DB00475Chlordiazepoxide4Completed2
DB00633Dexmedetomidine4Withdrawn1
DB00829Diazepam4Recruiting1
DB00996Gabapentin4Completed2
DB01221Ketamine4Withdrawn2
DB00186Lorazepam4Completed2
DB00186Lorazepam4Recruiting1
DB00186Lorazepam4Unknown Status1
DB00186Lorazepam4Withdrawn1
DB00842Oxazepam4Completed1
DB01174Phenobarbital4Recruiting1
DB01174Phenobarbital4Withdrawn1
DB09072Sodium oxybate4Completed1
DB00313Valproic acid4Completed1
DB00313Valproic acid4Unknown Status1
DB00829DiazepamNot AvailableCompleted2
DB00829DiazepamNot AvailableNot Yet Recruiting1
DB00829DiazepamNot AvailableRecruiting1
DB00186LorazepamNot AvailableCompleted1
DB01174PhenobarbitalNot AvailableCompleted1
DB01174PhenobarbitalNot AvailableNot Yet Recruiting1