Fibrinolytic Agents
- Name
- Fibrinolytic Agents
- Accession Number
- DBCAT000013
- Description
Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN. Some drugs in this category may have indirect fibrinolytic/thrombolytic effects.
- ATC Classification
- Drugs
Drug Drug Description Alteplase A recombinant form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli. Amediplase Investigated for use/treatment in myocardial infarction and thrombosis. Ancrod An anticoagulant purified from the venom of the Malayan pit viper that functions by inactivating circulating plasma fibrinogen. Not currently approved for use or marketed in any country. Anistreplase A form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli. Apadamtase alfa A recombinant human ADAMTS13 for enzyme replacement therapy in patients with congenital thrombotic thrombocytopenic purpura. Apafant Apafant is a small molecule drug. The usage of the INN stem '-pafant' in the name indicates that Apafant is a platelet-activating factor antagonist. Apafant has a monoisotopic molecular weight... Astaxanthin Investigated for use/treatment in eye disorders/infections, cancer/tumors (unspecified), and asthma. Benzarone Benzarone is a small molecule drug. Benzarone has a monoisotopic molecular weight of 266.09 Da. Brinase Not Annotated Cinnamic acid Not Annotated Defibrotide A mixture of single-stranded oligonucleotides used in the treatment of severe hepatic veno-occlusive disease with renal or pulmonary dysfunction following hematopoietic stem-cell transplantation. Dermatan sulfate A medication indicated to prevent deep vein thrombosis. Desmoteplase Investigated for use/treatment in cerebral ischemia and strokes. Dicoumarol For decreasing blood clotting. Often used along with heparin for treatment of deep vein thrombosis. Drotrecogin alfa A form of recombinant activated human protein C used to reduce mortality in patients with severe sepsis by inhibiting coagulation Factors V and VIII. Fibrinolysin Fibrinolysin assists with the healing of minor burns, superficial wounds, ulcers, surgical wounds, and superficial hematomas. Isbogrel Isbogrel is a small molecule drug. Isbogrel has a monoisotopic molecular weight of 281.14 Da. Limaprost An oral prostaglandin E1 analogue used to improve symptoms associated with thromboangiitis obliterans, acquired lumbar spinal canal stenosis, and other ischemic conditions. Linotroban Linotroban is a small molecule drug. Linotroban has a monoisotopic molecular weight of 341.04 Da. Monteplase Monteplase has been used in trials studying the treatment of Pulmonary Embolism. Pamiteplase Not Annotated Plasminogen Plasma-derived human plasminogen administered intravenously to treat type 1 plasminogen deficiency (hypoplasminogenemia). Protein C A medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis. Reteplase A purified form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli. Saruplase Not Annotated Streptokinase A purified fibrinolytic bacterial protein used to breakdown thrombosis in myocardial infarction, pulmonary embolism, and venous thromboembolism. Sulodexide A drug used to treat chronic venous ulcers in the legs. Sulotroban Sulotroban is a small molecule drug. Sulotroban has a monoisotopic molecular weight of 335.08 Da. Tenecteplase A modified form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction, pulmonary emboli, and ischemic stroke. Urokinase A low molecular weight form of human urokinase used to treat pulmonary embolism and myocardial infarction as well as to clear IV lines. Vapiprost Vapiprost is a small molecule drug. Vapiprost has a monoisotopic molecular weight of 477.29 Da.