- Fibrinolytic Agents
- Accession Number
Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN. Some drugs in this category may have indirect fibrinolytic/thrombolytic effects.
- ATC Classification
Drug Drug Description Alteplase A recombinant form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli. Reteplase A purified form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli. Anistreplase A form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli. Tenecteplase A modified form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli. Drotrecogin alfa A form of recombinant activated human protein C used to reduce mortality in patients with severe sepsis by inhibiting coagulation Factors V and VIII. Defibrotide A mixture of single-stranded oligonucleotides used in the treatment of severe hepatic veno-occlusive disease with renal or pulmonary dysfunction following hematopoietic stem-cell transplantation. Ancrod An anticoagulant purified from the venom of the Malayan pit viper that functions by inactivating circulating plasma fibrinogen. Not currently approved for use or marketed in any country. Sulodexide Sulodexide has been used clinically for the prophylaxis and treatment of vascular diseases with increased risk of thrombosis, including intermittent claudication, peripheral arterial occlusive disease and post-myocardial infarc-tion. Also investigated... Protein C A medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis. Brinase Not Annotated Saruplase Not Annotated Streptokinase A purified fibrinolytic bacterial protein used to breakdown thrombosis in myocardial infarction, pulmonary embolism, and venous thromboembolism. Desmoteplase Investigated for use/treatment in cerebral ischemia and strokes. Fibrinolysin Fibrinolysin assists with the healing of minor burns, superficial wounds, ulcers, surgical wounds, and superficial hematomas. Astaxanthin Investigated for use/treatment in eye disorders/infections, cancer/tumors (unspecified), and asthma. Urokinase A low molecular weight form of human urokinase used to treat pulmonary embolism and myocardial infarction as well as to clear IV lines. Dicoumarol For decreasing blood clotting. Often used along with heparin for treatment of deep vein thrombosis. Amediplase Investigated for use/treatment in myocardial infarction and thrombosis. Monteplase Monteplase has been used in trials studying the treatment of Pulmonary Embolism. Dermatan sulfate A medication indicated to prevent deep vein thrombosis.
- Drugs & Drug Targets