Imidazole and Triazole Derivatives

Name
Imidazole and Triazole Derivatives
Accession Number
DBCAT002195
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
TioconazoleAn imidazole antifungal used to treat vulvovaginal candidiasis.
MiconazoleAn azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
BifonazoleAn azole antifungal drug used to treat fungal skin infections, such as dermatomycosis.
SulconazoleA topical antifungal agent used for the treatment of tinea cruris, tinea corporis, and tinea versicolor caused by susceptible fungal strains.
LuliconazoleA topical antifungal agent used to treat fungal infections.
EfinaconazoleAn antifungal agent used to treat onychomycosis, a fungal infection of the nail.
FenticonazoleAn imidazole antifungal used to treat a variety of topical fungal infections.
ChlormidazoleNot Annotated
EberconazoleNot Annotated
FluconazoleA triazole antifungal used to treat various fungal infections including candidiasis.
OxiconazoleA topical antifungal used to treat a variety of dermatophyte infections.
ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
ThiabendazoleA benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections.
KetoconazoleA broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
EconazoleA topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.
SertaconazoleA topical antifungal agent used in the treatment of interdigital tinea pedis in immunocompetent patients.
IsoconazoleAn imidazole antifungal used for superficial skin and vaginal infections.
FlutrimazoleA topical antifungal used to treat pityriasis capitis and seborrheic dermatitis.
OmoconazoleNot Annotated
Drugs & Drug Targets
DrugTargetType
TioconazoleLanosterol 14-alpha demethylasetarget
TioconazoleCytochrome P450 19A1enzyme
TioconazoleCytochrome P450 2C19enzyme
TioconazoleCytochrome P450 2E1enzyme
TioconazoleCytochrome P450 3A4enzyme
TioconazoleCytochrome P450 51target
MiconazoleCytochrome P450 2C9enzyme
MiconazoleCytochrome P450 2D6enzyme
MiconazoleCytochrome P450 3A4enzyme
MiconazoleP-glycoprotein 1transporter
MiconazoleCytochrome P450 51target
MiconazoleNitric oxide synthase, endothelialtarget
MiconazoleNitric oxide synthase, inducibletarget
MiconazoleCytochrome P450 11B1, mitochondrialenzyme
MiconazoleCytochrome P450 2A6enzyme
MiconazoleCytochrome P450 2B6enzyme
MiconazoleCytochrome P450 2C19enzyme
MiconazoleCytochrome P450 2E1enzyme
MiconazoleNuclear receptor subfamily 1 group I member 2target
MiconazoleLanosterol 14-alpha demethylaseenzyme
MiconazoleCytochrome P450 19A1enzyme
MiconazoleCalcium-activated potassium channeltarget
MiconazoleVoltage-gated Potassium Channelstarget
MiconazoleInward rectifier potassium channeltarget
MiconazoleVoltage gated L-type calcium channeltarget
MiconazoleSerum albumincarrier
MiconazoleCytochrome P450 2C8enzyme
BifonazoleCytochrome P450 2B6target
BifonazoleCytochrome P450 51target
BifonazoleCytochrome P450 19A1enzyme
BifonazoleCytochrome P450 2E1enzyme
BifonazoleCytochrome P450 3A4enzyme
SulconazoleCytochrome P450 1A2enzyme
SulconazoleCytochrome P450 2C9enzyme
SulconazoleCytochrome P450 2D6enzyme
LuliconazoleCytochrome P450 51target
LuliconazoleCytochrome P450 3A4enzyme
LuliconazoleCytochrome P450 2C19enzyme
EfinaconazoleLanosterol 14-alpha demethylasetarget
FluconazoleCytochrome P450 3A4enzyme
FluconazoleCytochrome P450 2C9enzyme
FluconazoleCytochrome P450 2C19enzyme
FluconazoleP-glycoprotein 1transporter
FluconazoleCytochrome P450 51target
FluconazoleCytochrome P450 3A5enzyme
OxiconazoleCytochrome P450 51target
OxiconazoleLanosterol synthasetarget
OxiconazoleCytochrome P450 3A4enzyme
OxiconazoleCytochrome P450 2C19enzyme
OxiconazoleNuclear receptor subfamily 1 group I member 2target
ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
ClotrimazoleCytochrome P450 2D6enzyme
ClotrimazoleCytochrome P450 2C8enzyme
ClotrimazoleCytochrome P450 3A4enzyme
ClotrimazoleCytochrome P450 2B6enzyme
ClotrimazoleP-glycoprotein 1transporter
ClotrimazoleCytochrome P450 2A6enzyme
ClotrimazoleCytochrome P450 2C9enzyme
ClotrimazoleCytochrome P450 2E1enzyme
ClotrimazoleCytochrome P450 3A7enzyme
ClotrimazoleCytochrome P450 51target
ClotrimazoleNuclear receptor subfamily 1 group I member 2target
ClotrimazoleHydroxycarboxylic acid receptor 2target
ClotrimazoleBile salt export pumptransporter
ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
ClotrimazoleErgosteroltarget
ThiabendazoleFumarate reductase flavoprotein subunittarget
ThiabendazoleCytochrome P450 1A2enzyme
ThiabendazoleCytochrome P450 1A1enzyme
KetoconazoleCytochrome P450 3A4enzyme
KetoconazoleCytochrome P450 2C9enzyme
KetoconazoleCytochrome P450 2C19enzyme
KetoconazoleCytochrome P450 3A5enzyme
KetoconazoleCytochrome P450 1A2enzyme
KetoconazoleCytochrome P450 2C8enzyme
KetoconazoleCytochrome P450 1A1enzyme
KetoconazoleCytochrome P450 2D6enzyme
KetoconazoleBile salt export pumptransporter
KetoconazoleP-glycoprotein 1transporter
KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
KetoconazoleCytochrome P450 1B1enzyme
KetoconazoleCytochrome P450 2A6enzyme
KetoconazoleCytochrome P450 2B6enzyme
KetoconazoleLanosterol 14-alpha demethylasetarget
KetoconazoleAndrogen receptortarget
KetoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
KetoconazoleSteroid 21-hydroxylasetarget
KetoconazolePotassium voltage-gated channel subfamily H member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 2target
KetoconazoleNuclear receptor subfamily 1 group I member 3target
KetoconazoleUDP-glucuronosyltransferase 1-1enzyme
KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
KetoconazoleCytochrome P450 4F12enzyme
KetoconazoleLeukotriene-B(4) omega-hydroxylase 1enzyme
KetoconazoleSerum albumincarrier
KetoconazoleSex hormone-binding globulincarrier
KetoconazoleCytochrome P450 19A1enzyme
KetoconazoleUDP-glucuronosyltransferase 1-7enzyme
EconazoleCytochrome P450 19A1enzyme
EconazoleCytochrome P450 2E1enzyme
EconazoleCytochrome P450 3A4enzyme
EconazoleCytochrome P450 51target
EconazoleNuclear receptor subfamily 1 group I member 2target
SertaconazoleCytochrome P450 51target