Cytochrome P-450 CYP3A7 Inhibitors (moderate)

Name
Cytochrome P-450 CYP3A7 Inhibitors (moderate)
Accession Number
DBCAT003802
Description

Not Available

Drugs
DrugDrug Description
CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
CiprofloxacinA second generation fluoroquinolone used to treat various susceptible bacterial infections.
FluvoxamineA selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.
DiltiazemA calcium channel blocker used to treat hypertension and to manage chronic stable angina.
ErythromycinA macrolide antibiotic used to treat and prevent a variety of bacterial infections.
Drugs & Drug Targets
DrugTargetType
CimetidineHistamine H2 receptortarget
CimetidineCytochrome P450 1A2enzyme
CimetidineCytochrome P450 2D6enzyme
CimetidineCytochrome P450 2C19enzyme
CimetidineCytochrome P450 3A4enzyme
CimetidineCytochrome P450 3A5enzyme
CimetidineATP-dependent translocase ABCB1transporter
CimetidineSolute carrier family 22 member 2transporter
CimetidineSolute carrier family 22 member 1transporter
CimetidineSolute carrier family 22 member 3transporter
CimetidineOrganic cation/carnitine transporter 2transporter
CimetidineSolute carrier family 22 member 6transporter
CimetidineOrganic anion transporter 3transporter
CimetidineMultidrug and toxin extrusion protein 1transporter
CimetidineSolute carrier family 22 member 4transporter
CimetidineSolute carrier family 22 member 11transporter
CimetidineSolute carrier family 22 member 7transporter
CimetidineCytochrome P450 11B1, mitochondrialenzyme
CimetidineCytochrome P450 2C8enzyme
CimetidineCytochrome P450 2C9enzyme
CimetidineCytochrome P450 2E1enzyme
CimetidineFlavin-containing monooxygenase 3enzyme
CimetidineFlavin-containing monooxygenase 1enzyme
CimetidineBile salt export pumptransporter
CimetidineMultidrug and toxin extrusion protein 2transporter
CimetidineAlbumincarrier
CiprofloxacinDNA gyrase subunit Atarget
CiprofloxacinDNA topoisomerase 4 subunit Atarget
CiprofloxacinDNA topoisomerase 2-alphatarget
CiprofloxacinCytochrome P450 1A2enzyme
CiprofloxacinCytochrome P450 3A4enzyme
CiprofloxacinCytochrome P450 3A5enzyme
CiprofloxacinCytochrome P450 3A7enzyme
CiprofloxacinATP-dependent translocase ABCB1transporter
CiprofloxacinPotassium voltage-gated channel subfamily H member 2target
CiprofloxacinDNA gyrase subunit Atarget
CiprofloxacinDNA topoisomerase 4 subunit Atarget
CiprofloxacinDNA topoisomerase 4 subunit Btarget
CiprofloxacinDNA gyrase subunit Atarget
CiprofloxacinMultidrug resistance protein MdtKtarget
CiprofloxacinGyrase Atarget
CiprofloxacinDNA gyrase subunit Atarget
CiprofloxacinMultidrug and toxin extrusion protein 1transporter
CiprofloxacinMultidrug and toxin extrusion protein 2transporter
CiprofloxacinAlbumincarrier
CiprofloxacinThymidylate synthasetarget
CiprofloxacinDNA gyrase subunit Btarget
FluvoxamineSodium-dependent serotonin transportertarget
FluvoxamineCytochrome P450 1A2enzyme
FluvoxamineCytochrome P450 2D6enzyme
FluvoxamineCytochrome P450 2C9enzyme
FluvoxamineCytochrome P450 2C19enzyme
FluvoxamineCytochrome P450 1A1enzyme
FluvoxamineCytochrome P450 3A4enzyme
FluvoxamineCytochrome P450 3A Subfamilyenzyme
FluvoxamineATP-dependent translocase ABCB1transporter
FluvoxamineCytochrome P450 2B6enzyme
FluvoxaminePotassium voltage-gated channel subfamily H member 2target
FluvoxamineBile salt export pumptransporter
DiltiazemVoltage-dependent calcium channel gamma-1 subunittarget
DiltiazemCytochrome P450 3A4enzyme
DiltiazemCytochrome P450 2C19enzyme
DiltiazemCytochrome P450 2D6enzyme
DiltiazemCytochrome P450 3A5enzyme
DiltiazemCytochrome P450 3A7enzyme
DiltiazemATP-dependent translocase ABCB1transporter
DiltiazemCytochrome P450 2C8enzyme
DiltiazemAlbumincarrier
DiltiazemAlpha-1-acid glycoprotein 1carrier
DiltiazemVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DiltiazemVoltage-dependent calcium channel subunit alpha-2/delta-1target
Erythromycin23S ribosomal RNAtarget
ErythromycinCytochrome P450 3A4enzyme
ErythromycinCytochrome P450 3A7enzyme
ErythromycinATP-dependent translocase ABCB1transporter
ErythromycinSolute carrier organic anion transporter family member 1B1transporter
ErythromycinMotilin receptortarget
ErythromycinPotassium voltage-gated channel subfamily H member 2target
ErythromycinCytochrome P450 3A5enzyme
ErythromycinSolute carrier organic anion transporter family member 1B3transporter
ErythromycinBile salt export pumptransporter
ErythromycinATP-binding cassette sub-family C member 2transporter
ErythromycinSolute carrier organic anion transporter family member 1A2transporter