Cholangiocarcinoma (DBCOND0012992)

Identifiers

Synonyms
Cholangiocarcinomas / Intrahepatic bile duct carcinoma / Cholangiosarcoma / Cholangiocarcinoma NOS / Cholangiocarcinoma of biliary tract (disorder) / Cholangiocarcinoma (morphologic abnormality) / Bile duct adenocarcinoma / Bile duct cancer / Bile duct cancer NOS / Bile duct carcinoma / Carcinoma bile duct

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Capecitabine
A nucleoside metabolic inhibitor indicated to treat different gastrointestinal, including pancreatic cancer, and breast cancer.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04526106
REFOCUS: a First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients with ICC and Other Advanced Solid Tumorstreatment1 / 2active_not_recruiting
NCT04561453
Feasibility Study of Multi-Platform Profiling of Resected Biliary Tract CancerNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04566393
Expanded Access to Ulixertinib (BVD-523) in Patients with Advanced MAPK Pathway-Altered MalignanciesNot AvailableNot Availableavailable
NCT04645160
Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancerstreatment1 / 2recruiting
NCT05286814
M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinomatreatment2recruiting
NCT06607276
Adebrelimab Combined With Capecitabine for Adjuvant Therapy in Cholangiocarcinoma With High-risk Recurrence Post-surgerytreatment2not_yet_recruiting
NCT06607302
Ivosidenib in Locally Advanced or Metastatic Cholangiocarcinoma with IDH1 R132 Mutation After At Least One Prior Systemic Treatment - an Observational StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05712356
A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid Tumorstreatment2recruiting
NCT05876754
An Early Access Study of Ivosidenib in Patients With a Pretreated Locally Advanced or Metastatic Cholangiocarcinomatreatment3recruiting
NCT06048133
Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC)treatment2recruiting
NCT06358001
EchoTip AcuCore Post-Market Clinical StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06399757
A Study to Investigate APL-5125 in Adults With Advanced Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT06474091
Liquid Biopsy MonitORing of CholangioCarcinOma for Treatment Response and Prognostic Outcomes (MOROCCO)No drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT06503146
18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer DetectionNo drug interventionsdiagnostic2not_yet_recruiting
NCT05600803
Screening Single-operator Cholangioscopy for Neoplastic Bile Duct LesionsNo drug interventionsNot AvailableNot Availablerecruiting
NCT04480190
Neoadjuvant Therapy in Biliary Adenocarcinomatreatment1withdrawn
NCT02631590
Copanlisib (BAY 80-6946) in Combination With Gemcitabine and Cisplatin in Advanced Cholangiocarcinomatreatment2completed
NCT01868490
The Adoptive Immunotherapy for Solid Tumors Using Modified Autologous Cytokine-induced Killer CellsNo drug interventionstreatment1 / 2unknown_status
NCT04415190
the Impact of Early Palliative Care on the Survival of Locally Advanced and / or Metastatic Cholangiocarcinoma PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02436564
In Vitro Models of Liver and Pancreatic CancerNo drug interventionsNot AvailableNot Availableunknown_status
NCT04642664
Apatinib Plus Camrelizumab in Patients With Previously Treated Advanced Biliary Tract Cancertreatment2completed
NCT00955721
A Study of Combination of Gemcitabine, Oxaliplatin (GEMOX)-Sorafenib in Patients With Advanced Biliary Tract Cancertreatment1 / 2terminated
NCT04871321
Biomarker Discovery in Patients With Advanced Biliary Tract CancerNot AvailableNot Availablerecruiting
NCT06302621
Pemigatinib + Afatinib in Advanced Refractory Solid Tumorstreatment1recruiting
NCT05788484
A Study of CDX-585 in Patients With Advanced MalignanciesNo drug interventionstreatment1recruiting
NCT04764084
Niraparib Combined With Anlotinib in Homologous Recombination Repair (HRR) Gene-mutated Advanced Solid Tumorstreatment1unknown_status
NCT03027284
A Study of Merestinib (LY2801653) in Japanese Participants With Advanced or Metastatic Cancertreatment1completed
NCT03377179
A Study of ABC294640 (Yeliva ®) Alone and in Combination With Hydroxychloroquine Sulfate in Treatment of Patients With Advanced Cholangiocarcinomatreatment2completed
NCT00301379
Registry Study of Neoadjuvant Chemoradiation & Transplant for Cholangiocarcinoma PatientsNo drug interventionsNot AvailableNot Availableterminated
NCT03602079
Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 GeneNo drug interventionstreatment1 / 2completed
NCT03339843
Multiorgan Metabolic Imaging Response Assessment of Abemaciclibtreatment2completed
NCT00168987
Influence of an Oral Nutritional Supplement Rich in Omega-3 Fatty Acids on Functional State and Quality of Life in Malnourished Patients With Gastroenterological TumorsNo drug interventionstreatment4completed
NCT05411133
Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer PatientsNo drug interventionstreatment1recruiting
NCT02232633
A Study of BBI503 in Adult Patients With Advanced Hepatobiliary Cancertreatment2completed
NCT02482454
Radiofrquency Ablation Combined With Cytokine-induced Killer Cells for the Patients With CholangiocarcinomaNo drug interventionstreatment2 / 3active_not_recruiting
NCT00779454
Combined Biological Treatment and Chemotherapy for Patients With Inoperable Cholangiocarcinomatreatment2completed
NCT00708877
Liver Transplantation for CholangiocarcinomaNo drug interventionstreatmentNot Availableterminated
NCT03872947
A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumorstreatment1recruiting
NCT06441747
Phase II Study of the Combination of Durvalumab (MEDI4736) (PDL1 Inhibitor) and Olaparib (PARP Inhibitor) in Advanced Cholangiocarcinoma After Initial Chemotherapy and Durvalumab (BIL-PPP)treatment2not_yet_recruiting
NCT04385147
Advanced Endoscopy During COVID-19No drug interventionsNot AvailableNot Availablecompleted
NCT05694845
Evaluation of the Patient's Experience in Medical Studies for CholangiocarcinomaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06175845
Endoscopic Radiofrequency Ablation for Unresectable CholangiocarcinomaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01844245
Endobiliary RFA for Unresectable Malignant Biliary StricturesNo drug interventionstreatmentNot Availablecompleted
NCT01242605
ABC-04 a Study of Cisplatin, Gemcitabine and Selumetinib in Patients With Advanced Biliary Tract Cancertreatment1completed
NCT05012397
Milademetan in Advanced/Metastatic Solid Tumorstreatment2terminated
NCT06416397
Diagnostic Approach for Cholangiocarcinoma Using Liquid Bile BiopsyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03144661
An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other MalignanciesNo drug interventionstreatment1terminated
NCT03833661
M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer)treatment2completed
NCT04856761
A Study of Capecitabine Versus S-1 as Adjuvant Therapy in Patients With Biliary Tract Carcinoma After Surgical ResectionNot AvailableNot Availablerecruiting
NCT01151761
Phase II SBRT & Chemo for Unresectable Cholangiocarcinoma Followed by Liver Transplantationtreatment2terminated
NCT05348811
HAIC Combined With Donafenib and Sintilimab for Unresectable ICCtreatment2recruiting
NCT02027311
Etomidate vs. Midazolam for Sedation During ERCPtreatment4completed
NCT04572711
Prospective Evaluation of Biliary Tissue Sampling With ERCPNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT06434493
Evaluation of Combined Modality Protons and Hepatic Transplantation for Hilar CholangiocarcinomatreatmentNot Availablenot_yet_recruiting
NCT02479178
A Study of BIND-014 in Patients With Urothelial Carcinoma, Cholangiocarcinoma, Cervical Cancer and Squamous Cell Carcinoma of the Head and Necktreatment2terminated
NCT00653978
Unilateral Versus Bilateral Stents for Bismuth Type II and III Malignant Hilar StricturesNo drug interventionstreatment3unknown_status
NCT04099888
PCI Treatment/Gemcitabine & Chemotherapy vs Chemotherapy Alone in Patients With Inoperable Extrahepatic Bile Duct Cancertreatment2terminated
NCT03693807
A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinomatreatment2completed
NCT04037007
Efficacy of Fistulotomy for Biliary CannulationNo drug interventionstreatmentNot Availableunknown_status
NCT02638909
Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal Malignanciestreatment2terminated
NCT03665285
A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid TumorsNo drug interventionstreatment1 / 2completed
NCT03445585
Biobank for Cholestatic Liver Diseases.No drug interventionsNot AvailableNot Availablerecruiting
NCT01439685
Comparison of Biliary Stenting Alone vs. Stenting With Photodynamic Therapy (PDT) During ERCPNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01438385
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal DisordersNo drug interventionsNot AvailableNot Availableunknown_status
NCT02773485
Chemo Alone or in Combination With Radiation in Unresectable Cholangiocarcinomatreatment3recruiting
NCT04157985
Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumorstreatment3recruiting
NCT03150615
Enteral Nutrition After PancreaticoduodenectomyNo drug interventionspreventionNot Availablecompleted
NCT04238715
A Study of E7090 in Participants With Unresectable Advanced or Metastatic Cholangiocarcinoma With Fibroblast Growth Factor Receptor (FGFR) 2 Gene FusionNo drug interventionstreatment2active_not_recruiting
NCT05697237
Carlizumab Plus Sovantinib in Second-line Treatment of Advanced or Metastatic CholangiocarcinomaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01247337
Intra-hepatic Chemotherapy in Patient With Non-resectable Liver Metastases From Cholangiocarcinomatreatment2completed
NCT02232932
Liver Resection Versus Radio-chemotherapy-Transplantation for Hilar CholangiocarcinomaNo drug interventionstreatmentNot Availableunknown_status
NCT03111732
Pembrolizumab, a Monoclonal Antibody Against PD-1, in Combination With Capecitabine and Oxaliplatin (CAPOX) in People With Advanced Biliary Tract Carcinoma (BTC)treatment2completed
NCT02659852
A Study for Efficacy of Side-by-side Compared to Stent-in-stent Technique in the Endoscopic Management of Malignant Hilar Biliary ObstructionNo drug interventionstreatmentNot Availableunknown_status
NCT03907852
Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancertreatment1 / 2active_not_recruiting
NCT00733200
Surgical Treatment of Hilar Cholangiocarcinoma: Minor or Major Liver Resection?No drug interventionsNot AvailableNot Availablecompleted
NCT04742959
Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumorstreatment1 / 2completed
NCT02757859
High Volume Washing of the Abdomen in Increasing Survival After Surgery in Patients With Pancreatic Cancer That Can Be Removed by SurgeryNo drug interventionstreatmentNot Availablerecruiting
NCT05948475
Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinomatreatment3recruiting
NCT04584775
Implementing Acupuncture and Chinese Herbal Medicine Into Palliative CareNo drug interventionssupportive_careNot Availablewithdrawn
NCT04565275
A Study of ICP-192 in Patients With Advanced Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT01642875
Early Oral Versus Enteral Nutrition After PancreatoduodenectomyNo drug interventionsprevention4unknown_status
NCT02452970
RRx-001 in Second Line Treatment of Advanced Cholangiocarcinoma Prior to Readministration of First-Line Therapytreatment2terminated
NCT03895970
Lenvatinib Combined Pembrolizumab in Advanced Hepatobiliary Tumorstreatment2completed
NCT04919642
Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in Cholangiocarcinomatreatment2completed
NCT04430842
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072SNo drug interventionstreatment1completed
NCT00660699
A Feasibility Phase II Study in the Treatment of Resected Cholangiocarcinoma, Gallbladder, Pancreatic and Ampullary Cancerstreatment2completed
NCT02000999
Diagnosis of Bile Duct StricturesNo drug interventionsNot AvailableNot Availablecompleted
NCT04301999
Clinical Effect and Safety of PDT and RFA for Unresectable EHCCNo drug interventionstreatmentNot Availablecompleted
NCT05007106
MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)treatment2active_not_recruiting
NCT05718349
FGF19 in Obstructive Cholestasis: "Unveil the Signal"No drug interventionsNot AvailableNot Availablerecruiting
NCT05655949
Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangiotreatment2recruiting
NCT00160836
Biliary Tissue Sampling Using a Cytology Brush or the GIUM CatheterNo drug interventionsdiagnostic1unknown_status
NCT01755013
Photodynamic Therapy (PDT) for Palliation of CholangiocarcinomaNo drug interventionssupportive_care2 / 3unknown_status
NCT02834013
Nivolumab and Ipilimumab in Treating Patients With Rare Tumorstreatment2active_not_recruiting
NCT00973713
Study of RAD001 in Advanced Cholangiocarcinoma: RADiCholtreatment2unknown_status
NCT05678218
Preoperative Evaluation of Lymph Nodes of CholangiocarcinomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT04989218
Durvalumab and Tremelimumab With Platinum-based Chemotherapy in Intrahepatic Cholangiocarcinoma (ICC)treatment1 / 2terminated
NCT06440018
INSPIRE: A Multi-Cancer Early Detection StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01525719
Single Arm Study of RAD001 as Monotherapy in Treatment in Advanced Cholangiocarcinomatreatment2unknown_status
NCT04727541
Neoadjuvant Bintrafusp Alfa in Patients With Resectable Biliary Tract Cancertreatment2terminated
NCT05653817
Advanced or Metastatic CholangiocarcinomatreatmentNot Availablenot_yet_recruiting
NCT01595217
MRCP Diagnoses EHCC Better When Combined DWINo drug interventionsdiagnosticNot Availablecompleted
NCT05714124
Liver Embolization Approaches for Tumor ManagementNo drug interventionsNot AvailableNot Availablerecruiting
NCT03951324
Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00290316
Accuracy of Endoscopic Ultrasound for Detection of Tumors of the LiverNo drug interventionsdiagnostic2unknown_status
NCT05641896
Study of [18F]FAPI-74 PET in Patients With Gastrointestinal CancersNo drug interventionsdiagnostic2recruiting
NCT01213758
Changes in Liver Function After Stereotactic Body Radiation Therapy Measured by PET/CTNo drug interventionsNot AvailableNot Availablecompleted
NCT03438435
Fluorescence QRH-882260 Peptide Imaging in the Bile DuctNo drug interventionsdiagnostic1completed
NCT00948935
Study of Gemcitabine, Irinotecan and Panitumumab in Patients With Advanced and Metastatic Biliary Tract Adenocarcinomatreatment2completed
NCT05207735
PD-1 Inhibitor Sintilimab Combined With Capecitabine for Adjuvant Treatment After Radical Resection of Cholangiocarcinoma.treatment2not_yet_recruiting
NCT00869635
S-1 and Photodynamic Therapy in CholangiocarcinomaNo drug interventionstreatment3completed
NCT04792463
Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition SyndromeNo drug interventionsNot AvailableNot Availablerecruiting
NCT05028439
RFA Combined With Chemotherapy for Unresectable CholangiocarcinomatreatmentNot Availablecompleted
NCT05461430
Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)No drug interventionsNot AvailableNot Availablerecruiting
NCT01145248
Comparison of Biliary Forceps Biopsy and Brush CytologyNo drug interventionsdiagnosticNot Availablecompleted
NCT04985357
Defining the Clinical Potential of Mass Response as a Biomarker for Patient Tumor Sensitivity to DrugsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02528526
Effects of OXY111A in Primary and Secondary Hepato-Pancreato-Biliary NeoplasmNo drug interventionstreatment1 / 2unknown_status
NCT03734926
A Phase 1 Study of ZSP1241 in Participants With Advanced Solid TumorsNo drug interventionstreatment1unknown_status
NCT03267966
Margin Status After Pancreaticoduodenectomy for CancerNo drug interventionsdiagnosticNot Availablecompleted
NCT06304766
Open Versus Laparoscopic Ablation of Liver MalignanciesNo drug interventionstreatmentNot Availablerecruiting
NCT00604266
Coregistration of 18F-FDG-PET and MRI in the Staging of Potentially Resectable Hilar Cholangiocarcinoma: a Pilot StudyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT05215665
GEMOX Combined With Targeted Therapy and Immunotherapy for Patients With Advanced CholangiocarcinomatreatmentNot Availablerecruiting
NCT03003065
Safety and Tumoricidal Effect of Low Dose Foscan PDT in Patients With Inoperable Bile Duct Cancerstreatment2completed
NCT01739465
Comparison of Endoscopic Radiofrequency Ablation Versus Photodynamic Therapy for Inoperable CholangiocarcinomaNo drug interventionstreatment2 / 3unknown_status
NCT03452774
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT03473574
Durvalumab and Tremelimumab With Gemcitabine or Gemcitabine/Cisplatin Compared to Gemcitabine/Cisplatin in CCA Patientstreatment2completed
NCT04308174
Neoadjuvant Gemcitabine Plus Cisplatin With or Without Durvalumab in Resectable Biliary Tract Cancertreatment2active_not_recruiting
NCT02128282
Study of CX-4945 in Combination With Gemcitabine and Cisplatin for Frontline Treatment of Cholangiocarcinomatreatment1 / 2completed
NCT05967182
A Single-Arm Study of Pembrolizumab With Gemcitabine and Cisplatin as Perioperative Therapy for Potentially Resectable Intrahepatic Cholangiocarcinomatreatment2recruiting
NCT03042182
Trial of Therapeutic Vaccine in Patients With CholangiocarcinomaNo drug interventionstreatment1 / 2unknown_status
NCT02012231
Phase I/IIa Study to Evaluate the Safety, PK, PD, and Preliminary Efficacy of PLX8394 in Patients With Advanced Cancers.treatment1terminated
NCT05497531
Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic CancersNo drug interventionsdiagnosticNot Availablerecruiting
NCT01522573
T-EUS for Gastrointestinal Disorders: A Multicenter RegistryNo drug interventionsNot AvailableNot Availableunknown_status
NCT06355427
The Effect of [18F] F-FAPI PET-CT on Management in Patients With Proximal CholangiocarcinomaNo drug interventionsdiagnostic2 / 3not_yet_recruiting
NCT04668976
A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinomatreatment2recruiting
NCT02073994
Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutationtreatment1completed
NCT04100694
Early Access Program Providing HER2/HER3 Bispecific Antibody, MCLA-128, for a Patient With Advanced NRG1-Fusion Positive Solid TumorNot AvailableNot Availableavailable
NCT04068194
Testing the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Metastatic Solid Tumors and Hepatobiliary Malignanciestreatment1 / 2recruiting
NCT04149691
Safety, Tolerability and Pharmacokinetics of Oral CPL304110, in Adult Subjects With Advanced Solid MalignanciesNo drug interventionstreatment1recruiting
NCT06010862
Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced/Metastatic Malignant Solid TumorsNo drug interventionstreatment1recruiting
NCT04059562
Trifluridine/Tipiracil in Combination With Irinotecan as a Second Line Therapy in Patients With Cholangiocarcinomatreatment2completed
NCT03041662
Surveillance Study for Early Detection of Cholangiocarcinoma (CCA) in Primary Sclerosing Cholangitis (PSC)No drug interventionsNot AvailableNot Availablecompleted
NCT06037980
CisPlatin plUs Gemcitabine and Nabpaclitaxel (GAP) as pReoperative Chemotherapy Versus Immediate Resection in patIents With resecTable BiliarY Tract Cancers (BTC) at High Risk for Recurrencetreatment2 / 3recruiting
NCT02375880
Study of DKN-01 and Gemcitabine/Cisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic Biliary System or Gallbladdertreatment1completed
NCT06369480
Prognostic Factors for Survival in Patients With CholangiocarcinomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT03414489
Expanded Access for the Treatment of Advanced Cholangiocarcinoma With ABC294640 (Yeliva ®)Not AvailableNot Availableavailable
NCT04137289
A Study to Find a Safe and Effective Dose of BI 905711 in Patients With Advanced Gastrointestinal CancerNo drug interventionstreatment1completed
NCT03774589
Bilioenteric Anastomosis by Magnetic Compressive TechniqueNo drug interventionstreatmentNot Availableunknown_status
NCT05321992
Evaluating a Community-Based Behaviour Change Communication Model to Prevent Cholangiocarcinoma in Khon Kaen, ThailandNo drug interventionspreventionNot Availablenot_yet_recruiting
NCT02628067
Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)treatment2recruiting
NCT05872867
Study of WM-A1-3389 in Participants With Advanced or Metastatic Solid Tumors and Non-Small Cell Lung Cancer (MK-3475-E90/KEYNOTE-E90)treatment1recruiting
NCT04306367
Study of Pembrolizumab and Olaparib in Bile Duct Cancertreatment2active_not_recruiting
NCT02568267
Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)treatment2active_not_recruiting
NCT04233567
Infigratinib for the Treatment of Advanced or Metastatic Solid Tumors in Patients With FGFR Gene Mutationstreatment2active_not_recruiting
NCT01501604
BKM120 in Cancers With PIK3CA Activating Mutationstreatment2withdrawn
NCT04504604
TCF-001 TRACK (Target Rare Cancer Knowledge) StudyNo drug interventionsdiagnosticNot Availablerecruiting
NCT05194072
A Study of SGN-B7H4V in Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT01043172
A Study of Gemcitabine as an Adjuvant Treatment for Cholangiocarcinoma After Surgical Resectiontreatment2completed
NCT03102268
ncRNAs in Exosomes of CholangiocarcinomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT03211169
Comparison Bile Duct Brushings, Cholangioscopy-Directed Biopsies and Pediatric Forceps Biopsies in Biliary StricturesNo drug interventionsdiagnosticNot Availableterminated
NCT01859169
Safety and Efficiency of Photodynamic Therapy for Blie Duct CarcinomaNo drug interventionsNot AvailableNot Availablesuspended
NCT06340646
Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)No drug interventionshealth_services_researchNot Availablerecruiting
NCT04568512
DNA Methylation Biomarker for Diagnosis of Cholangiocarcinoma in Patients With Bile Duct StrictureNo drug interventionsdiagnosticNot Availablecompleted
NCT02649712
Unilateral Stenting Versus Bilateral Stenting for Malignant Hilar Biliary ObstructionNo drug interventionstreatmentNot Availablecompleted
NCT05187312
Registry for Advanced EndoscopyNo drug interventionsNot AvailableNot Availablerecruiting
NCT04383210
Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumorstreatment2active_not_recruiting
NCT02990481
A Study of TRK-950 in Patients With Advanced Solid TumorsNo drug interventionstreatment1completed
NCT02548195
Oxaliplatin+Gemcitabine vs Capecitabine as Adjuvant Therapy for Intrahepatic Cholangiocarcinomaprevention3unknown_status
NCT02784795
A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumorstreatment1completed
NCT02428855
Phase II Trial of Dasatinib in Patients With Isocitrate Dehydrogenase (IDH)-Mutant Advanced Intrahepatic Cholangiocarcinomatreatment2completed
NCT00465023
Proton Beam Irradiation for the Treatment of Unresectable Hepatocellular Cancer or Hepatic MetastasesNo drug interventionstreatmentNot Availablecompleted
NCT06363123
Plasma Metabolic Biomarkers for Multi-Cancer DiagnosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT02592538
Endobiliary Radiofrequency Ablation With S-1 for Unresectable CholangiocarcinomaNo drug interventionstreatmentNot Availablecompleted
NCT06260943
Targeted Navigation in Hepatocellular Carcinoma (HCC)No drug interventionssupportive_careNot Availablerecruiting
NCT05506943
A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002)treatment2 / 3active_not_recruiting
NCT05451043
Durvalumab and Tremelimumab in Combination With Propranolol and Chemotherapy for Treatment of Advanced Hepatopancreabiliary Tumors (BLOCKED)treatment2recruiting
NCT04440943
A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced MalignanciesNo drug interventionstreatment1completed
NCT03943043
Gemcitabine + Oxaliplatin +Nab-paclitaxel in Subjects With Advanced Biliary Tract Cancertreatment1 / 2unknown_status
NCT01920503
International Registry on Cholangiocarcinoma TreatmentNot AvailableNot Availableunknown_status
NCT02170090
Adjuvant Chemotherapy With Gemcitabine and Cisplatin Compared to Standard of Care After Curative Intent Resection of Biliary Tract Cancertreatment3active_not_recruiting
NCT00630890
Cyberknife Radiosurgery Boost for Hilar Cholangiocarcinoma (Klatskin Tumor)No drug interventionstreatment1terminated
NCT06341764
Neo-adjuvant Chemo and Immunotherapy in The Pre-operAtive Treatment of Locally Advanced cholangIOcarciNomatreatment2recruiting
NCT02762721
Analysis of Oncogenes in Intrahepatic Cholangiocarcinoma or Mixed Hepatocellular-Cholangiocarcinoma in Tumor Tissue SamplesNo drug interventionsNot AvailableNot Availablecompleted
NCT00797121
Preoperative Biliary Drainage for Resectable Hilar CholangiocarcinomaNo drug interventionsprevention4unknown_status
NCT01673802
The Role of Gadoxetate (Eovist) Enhanced CT in Evaluating CholangiocarcinomaNo drug interventionstreatment0completed
NCT05346484
A Study of CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adults With Metastatic or Advanced Solid Tumorstreatment1recruiting
NCT04028479
The Registry of Oncology Outcomes Associated With Testing and TreatmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT04717687
Pilot Study on the Evaluation of Irreversible Electroporation Technique in Infiltrating Perihilar CholangiocarcinomaNo drug interventionstreatmentNot Availablewithdrawn
NCT00713687
Gemcitabine/Oxaliplatin and Photodynamic Therapy in Cholangiocarcinomatreatment2withdrawn
NCT04676633
Safety, Tolerability, PK, Anti-Tumor Activity of STP705 in Subjects With Advanced/Metastatic or Surgically Unresectable Solid Tumors Who Are Refractory to Standard Therapytreatment1completed
NCT04566133
Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC).treatment2terminated
NCT01438554
Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinomaother1completed
NCT02821754
A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)treatment2completed
NCT03769753
Trial of IRE in CholangiocarcinomaNo drug interventionstreatment2completed
NCT00350753
Avastin and Tarceva for Upper Gastrointestinal Cancerstreatment2completed
NCT01912053
Efficacy Study of Intra-hepatic Administration of Therasphere® in Association With Intravenous Chemotherapy to Treat CholangiocarcinomaNo drug interventionstreatment2completed
NCT05253053
To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumorstreatment1 / 2recruiting
NCT02379377
18F-FSPG PET in Imaging Patients With Liver Cancer Before Undergoing Surgery or Transplantdiagnostic1recruiting
NCT03207347
A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001)treatment2completed
NCT00230347
Evaluation of Stereotactic Radiosurgery For Liver MalignanciesNo drug interventionstreatment1completed
NCT01439698
Radio Frequency Ablation in the Management of Pancreatico-biliary Disorders: A Multicenter RegistryNo drug interventionsNot AvailableNot Availableunknown_status
NCT06490198
Phase 2 Study: OBI-833/OBI-821 Maintenance for Globo H+ Advanced Biliary Tract Cancer After Gemcitabine/Cisplatintreatment1not_yet_recruiting
NCT05519605
Bile Duct Drainage After ERCP Failure: EUS-BD vs PTBDNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03801083
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Biliary Tract CancersNo drug interventionstreatment2recruiting
NCT00350961
Gemcitabine, Oxaliplatin and Capecitabine in Patients With Advanced Cholangiocarcinomatreatment1 / 2completed
NCT04076761
Study of TRIFLURIDINE/TIPIRACIL in Previously Treated Cholangiocarcinomatreatment2terminated
NCT05580328
An Exploratory Clinical Study of Photodynamic Therapy Combined With Sonodynamic Therapy in CholangiocarcinomatreatmentNot Availablenot_yet_recruiting
NCT02167711
Treatment for Bile Duct Cancer in the Livertreatment2completed
NCT02730611
Metabolic Syndrome, Bile Acids, Hepatocellular Carcinoma and CholangiocarcinomaNo drug interventionsNot AvailableNot Availablecompleted
NCT05432193
FAPi Radioligand OpeN-Label, Phase 1 Study to Evaluate Safety, Tolerability and DosImetry of [Lu-177]-PNT6555; A Dose Escalation Study for TReatment of Patients With Select Solid Tumors (FRONTIER)treatment1active_not_recruiting
NCT03999593
Long-term Morbidity After Surgery for Perihilar CholangiocarcinomaNo drug interventionsNot AvailableNot Availablecompleted
NCT02106871
Study of Sildenafil as a Therapy for Fatigue in Pancreatic Cancersupportive_care1withdrawn
NCT05518071
FLUOPANC-trial - Fluorescence-guided Surgery of Pancreatic and Bileduct Tumors Using cRGD-ZW800-1No drug interventionstreatment2completed
NCT02052778
A Study of TAS-120 in Patients With Advanced Solid Tumorstreatment1 / 2completed
NCT04316078
A Novel Patient Engagement Platform Among Patients With Gastrointestinal MalignanciesNo drug interventionshealth_services_researchNot Availablecompleted
NCT03486678
SHR-1210 in Combination With GEMOX in Patients With Advanced BTCtreatment2completed
NCT03517488
A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumorstreatment1completed
NCT03140007
Diagnostic Accuracy of ERCP-guided Versus Cholangioscopy-guided Tissue Acquisition in Patients With Indeterminate Biliary Strictures Suspected to be Intrinsic .No drug interventionsotherNot Availableunknown_status
NCT03178409
Combined HCC-MFCCCNo drug interventionsNot AvailableNot Availablecompleted
NCT06290856
Clinical Utility of Selected Circulating Tumor DNA Assays in Patients With Advanced MalignancyNo drug interventionsNot AvailableNot Availablerecruiting
NCT02585856
Efficacy and Safety of Photodynamic Therapy for Unresectable CholangiocarcinomaNo drug interventionstreatmentNot Availablecompleted
NCT04644315
A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumorstreatment2terminated
NCT03801915
Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal CancersNo drug interventionstreatment2completed
NCT04913337
Study of NGM707 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumor Malignanciestreatment1 / 2active_not_recruiting
NCT01135732
Cytological Evaluation of Biliary Epithelium After Endoscopic SphincterotomyNo drug interventionsNot AvailableNot Availablecompleted
NCT03172832
A Trial of Percutaneous vs. Endoscopic Drainage of Suspected Klatskin TumorsNo drug interventionstreatmentNot Availableterminated
NCT03991832
Study of Olaparib and Durvalumab in IDH-Mutated Solid Tumorstreatment2recruiting
NCT04445532
Hepatobiliary Tumors Tissue Samples AcquisitionNo drug interventionsNot AvailableNot Availablerecruiting
NCT03563352
Nutritional Preferences and Product Accessibility in Oral Nutritional Supplements in Participants With Breast, Colorectal, Upper Gastrointestinal, or Prostate CancerNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01007552
A Study of Gemcitabine, Capecitabine and Bevacizumab to Treat Cancer of the Gall Bladder or Bile Ductstreatment2completed
NCT05921552
Senior Adult Hepatobiliary Prehab StudyNo drug interventionssupportive_careNot Availablerecruiting
NCT06541652
A French Multicenter Observational Retrospective Study of Rare Primary Liver CancersNo drug interventionsNot AvailableNot Availablerecruiting
NCT05184400
Identification of New Biomarkers for Patients With Cholangiocarcinoma and Gallbladder CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT01434459
Study of Gemcitabine With TheraSphere® (Yttrium-90)in Patients With Hepatic Tumors of Pancreatobiliary Origintreatment1terminated
NCT05292859
Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01303159
Endoscopic Bipolar Radiofrequency Probe (ENDOHPB) in the Management of Unresectable Bile Duct and Pancreatic CancerNo drug interventionstreatmentNot Availableterminated
NCT02917759
Liver and Biliary Tumor Tissue RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT02174575
Anesthetic Agents and Acute Kidney Injury After Liver Resection Surgeryprevention4withdrawn
NCT05596370
Association Between Cell-free Nucleic Acid in Blood, Urine and Microbiome in Stool With Pancreatobiliary CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT03278106
TAS-102 in Treating Advanced Biliary Tract Cancerstreatment2completed
NCT05464706
Study on the Quality of Life (QoL) After Liver SurgeryNo drug interventionssupportive_careNot Availablecompleted
NCT06126406
Clinical Study of CEA Targeting Chimeric Antigen Receptor T Lymphocytes(CAR-T) for CEA Positive Advanced Malignant Solid TumorsNo drug interventionstreatment1recruiting
NCT05451849
A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancertreatment1 / 2active_not_recruiting
NCT00955149
Erlotinib for Chemoprevention in Trisomy 7 Positive Primary Sclerosing Cholangitis (PSC)prevention1completed
NCT01206049
Combination Chemotherapy Plus Panitumumab or Bevacizumab for Inoperable Cholangiocarcinoma Without KRAS Mutationstreatment2completed
NCT04656249
Lenvatinib in Patients With Previously Treated Advanced Biliary Tract Cancertreatment2completed
NCT01875549
Comparison Between Unilateral Versus Bilateral Stenting for Malignant Hilar Biliary Obstruction to Use a LCD StentNo drug interventionstreatmentNot Availablewithdrawn
NCT01290536
Yttrium-90 Radioembolization Using Glass Microspheres (TheraSphere) for Patients With Liver MetastasesNo drug interventionstreatment2completed
NCT04866836
A Study of Tislelizumab Combined With Radiotherapy as the Second-line Treatment of Advanced Biliary Malignant Tumorstreatment2unknown_status
NCT03166436
RFA for Malignant Biliary ObstructionNo drug interventionstreatmentNot Availableunknown_status
NCT01926236
Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract Cancerstreatment3completed
NCT04484636
PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study)No drug interventionsotherNot Availablerecruiting
NCT03829436
TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancerstreatment1completed
NCT03852836
Evaluation of MRI Sequences for Ultra-rapid Acquisition of Bile Ducts ImagesNo drug interventionsdiagnosticNot Availableterminated
NCT00907413
Photodynamic Therapy (PDT) Trial for Palliation of CholangiocarcinomaNo drug interventionstreatment3terminated
NCT06370013
Rollover Study to Provide Continued Access to TT-00420 (Tinengotinib) for Subjects With Advanced Solid TumorsNot AvailableNot Availableavailable
NCT00320918
Chart Review: Unresectable/Metastatic Cholangiocarcinoma Treated With Irinotecan, Capecitabine and CelecoxibNo drug interventionsNot AvailableNot Availableterminated
NCT05311618
Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumorstreatment1active_not_recruiting
NCT04648319
A Study of BMS-936558 With SBRT After Induction Chemotherapy in Cholangiocarcinomatreatment2terminated
NCT02582541
Endoscopic Biliary RFA of Malignant Bile Duct ObstructionNo drug interventionstreatmentNot Availableunknown_status
NCT04145141
National Translational Science Network of Precision-based Immunotherapy for Primary Liver CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT02496741
Metformin And Chloroquine in IDH1/2-mutated Solid Tumorstreatment1 / 2completed
NCT02520141
Ramucirumab in Treating Patients With Advanced or Metastatic, Previously Treated Biliary Cancers That Cannot Be Removed by Surgerytreatment2completed
NCT04853017
A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid TumorsNo drug interventionstreatment1active_not_recruiting
NCT03603834
Neoadjuvant mFOLFOXIRI for Potentially Resectable Cholangiocarcinomatreatment2unknown_status
NCT02181634
Phase II Trial of Nab-Paclitaxel and Gemcitabine for First-Line Treatment of Patients With Cholangiocarcinomatreatment2completed
NCT01442324
Pilot Study of Irreversible Electroporation (IRE) to Treat Metastatic Liver Cancer & CholangiocarcinomaNo drug interventionstreatmentNot Availableunknown_status
NCT01855724
Clinical Trial to Investigate the Efficacy of Treatment With Gemcitabine/Pazopanib in Patients With Biliary Tree Cancertreatment2terminated
NCT06258824
MicroRNAs as Bile-based Biomarkers in Pancreaticobiliary CancersNo drug interventionsNot AvailableNot Availablecompleted
NCT06369896
Digital Single-operator Cholangioscopy and Intraductal Ultrasound for Nonicteric Biliary StricturesNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04753996
Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02609958
ASLAN001 in Patients With Advanced or Metastatic Cholangiocarcinoma Who Progressed on at Least 1 Line of Systemic Therapytreatment2completed
NCT03896958
The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)No drug interventionsNot AvailableNot Availableunknown_status
NCT01900158
A Phase I/II Safety and Efficacy Study of PCI of Gemcitabine and Chemotherapy in Patients With Cholangiocarcinomastreatment1completed
NCT00540735
Efficiency Evaluation of Photodynamic Therapy With Photofrin® on Unresectable Type III or IV CholangiocarcinomasNo drug interventionstreatment3terminated
NCT03779035
Adjuvant Chemotherapy for Biliary Tract Cancer After Curative Resectiontreatment3unknown_status
NCT05194735
Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumorstreatment1 / 2active_not_recruiting
NCT05721963
Study on the Accuracy of Proteomics in Evaluating Lymph Node Metastasis Status in Cholangiocarcinoma PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT05724563
Domvanalimab and Zimberelimab in Advanced Liver Cancerstreatment2recruiting
NCT04340986
Cohort of Patients With Hepatocellular Carcinoma or CholangiocarcinomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05179486
Molecular Epidemiology of Biliary Tree CancersNo drug interventionsNot AvailableNot Availablerecruiting
NCT04521686
Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutationstreatment1active_not_recruiting
NCT04683939
Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumorstreatment1 / 2terminated
NCT00975039
Study Using WST11 in Patients With Non-Resectable or Inoperable CholangiocarcinomaNo drug interventionstreatment2terminated
NCT06438822
Cadonilimab Combined With Liposomal Irinotecan Plus Leucovorin and Fluorouracil for Advanced Cholangiocarcinomatreatment2not_yet_recruiting
NCT01963325
S-1 in Combination With Abraxane in Treating Cholangiocarcinomatreatment2completed
NCT01915225
Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT04637048
Observational Study on Patients With Hepatobiliary TumorsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02393248
Open-Label, Dose-Escalation Study of Pemigatinib in Subjects With Advanced Malignancies - (FIGHT-101)treatment1 / 2terminated
NCT03792048
Magnetic Compressive Anastomosis for Biliojejunostomy and Pancreaticojejunostomy During Whipple's ProcedureNo drug interventionstreatmentNot Availableunknown_status
NCT01253148
Study Of Intrahepatic Arterial Injection of 90-Y Glass Microspheres for CholangiocarcinomaNo drug interventionstreatmentNot Availablecompleted
NCT06381648
Detecting Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma (LyMIC)No drug interventionsNot AvailableNot Availablerecruiting
NCT04243057
Diagnosis, Treatment Status and Prognosis of Cholangiocarcinoma in China: a Multicenter, Two-way, Non-intervention StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02607826
Short-term Starvation vs. Normal Diet Before Chemotherapy of Solid TumorsNo drug interventionssupportive_careNot Availableunknown_status
NCT03924466
Repeatability of 68-GaNOTA-Anti-HER2 VHH1 PET/CT in Breast Carcinoma PatientsNo drug interventionsdiagnostic2recruiting
NCT02351765
ABC-08: Phase Ib Trial of Acelarin in Combination With Cisplatin in Locally Advanced/ Metastatic Biliary Tract Cancerstreatment1completed
NCT06570174
Oral Protein Supplements for Nutritional and Quality of Life Improvement After Pancreatic Resection in Elderly PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT01392274
pCLE For the Diagnosis Of Cancer in Unknown Bile Duct StrictureNo drug interventionsNot AvailableNot Availablecompleted
NCT01721174
Endoscopic Biliary Radiofrequency Ablation of Malignant Distal Common Bile Duct StricturesNo drug interventionstreatmentNot Availableterminated
NCT05215574
Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumorstreatment1recruiting
NCT04421820
BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid TumoursNo drug interventionstreatment1 / 2recruiting
NCT04633382
ENHANCED RECOVERY AFTER BILIARY TRACT SURGERYNo drug interventionstreatmentNot Availableunknown_status
NCT03499782
Precise Treatment System of Biliary Malignancies Based on Special Disease DatabaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT02872831
Beacon BNX™ Endoscopic Ultrasound (EUS)-Needle vs SharkCore™ NeedleNo drug interventionstreatmentNot Availableterminated
NCT02081131
Pancreatic Head and Peri-ampullary Cancer Laparoscopic vs Open Surgical Treatment Trial (PLOT)No drug interventionstreatmentNot Availablecompleted
NCT04459273
Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancersbasic_science1recruiting
NCT03250273
A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic Adenocarcinomatreatment2completed
NCT04946773
Deep Liver Phenotyping and Immunology StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03644173
Personal Resilience Empowerment Program StudyNo drug interventionssupportive_careNot Availablecompleted
NCT05510427
Phase Ib Trial of Infigratinib In Combination With Atezolizumab And Bevacizumab for The Second-Line Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion/Amplificationtreatment1withdrawn
NCT03079427
Adjuvant Capecitabine vs Gemcitabine Plus Cisplatin in Resected Extrahepatic Cholangiocarcinomatreatment2completed
NCT04802876
Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumorstreatment2recruiting
NCT02468076
Radiofrequency Ablation for Biliopancreatic MalignancyNo drug interventionstreatment2completed
NCT02924376
Efficacy and Safety of Pemigatinib in Subjects With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma Who Failed Previous Therapy - (FIGHT-202)treatment2completed
NCT05634694
Study on Consistency Evaluation for Drug Sensitivity of Patient-Derived Organoid Model From Cholangiocarcinoma PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02665494
Biliary Cancer in Italy: a Study on Cholangiocarcinoma cAUSEs and Risk FactorsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04066491
Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTCtreatment2 / 3terminated
NCT03338062
A Pilot Study to Assess Theragnostically Planned Liver Radiation to Optimize Radiation TherapyNo drug interventionsdiagnosticNot Availablecompleted
NCT04256980
Pemigatinib in Treating Patients With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma Including FGFR2 Rearrangementtreatment2completed
NCT00426829
Proton Therapy and Bevacizumab for Primary Liver Tumorstreatment1terminated
NCT05993429
Diagnostic Efficacy of EUS-FNA/B Versus ERCP With or Without POCS-TB in Patients With Suspected Hilar CholangiocarcinomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT02374489
A Phase II Trial of LDK378 in ROS1 and /or ALK Over-expressed Advanced Intrahepatic or Hilar Cholangiocarcinomatreatment2terminated
NCT06048289
Prospective Observational Study to Predict the Response of Biliary Tract Tumors to ImmunotherapyNo drug interventionsNot AvailableNot Availablerecruiting
NCT01267344
A Randomized Study of GEMOX With or Without Cetuximab in Locally Advanced and Metastatic BTCtreatment2completed
NCT00660140
Study of Gemcitabine and Carboplatin in the Treatment of Metastatic or Recurrent Cholangiocarcinoma/Gallbladder Cancertreatment2completed
NCT04510740
Liver Cancer Registry PlatformNo drug interventionsNot AvailableNot Availablerecruiting
NCT04077372
Assessment of a Serious Illness Conversation Guide (SICG) in Advanced Gastro-Intestinal CancersNo drug interventionssupportive_careNot Availableterminated
NCT05563272
89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumorsdiagnostic2recruiting
NCT03219268
A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasmstreatment1completed
NCT03613168
Trastuzumab in HER2-positive Biliary Tract Cancertreatment2completed
NCT03637569
The Relationship Between Triceps Skinfold and Overall Survival of Pancreas, Bile Duct, Gallbladder CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT01525069
Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic Cholangiocarcinomatreatment1terminated
NCT01673269
Prospective Study of the Risk of Bacteremia in Directed Cholangioscopic Examination of the CBDNo drug interventionsdiagnosticNot Availablecompleted
NCT04895046
Maintenance Niraparib and Dostarlimab in Advanced Cholangiocarcinomatreatment2withdrawn
NCT02626312
Radiation Therapy in Treating Patients With Hepatocellular Carcinoma, Cholangiocarcinoma, or Liver Metastasis Who Have Impaired Liver FunctionNo drug interventionstreatment1active_not_recruiting
NCT03820310
Clinical Trial of Autologous Tcm Immunotherapy in ICCNo drug interventionstreatment2recruiting
NCT04304781
Phase 1 In-vivo Biliary Study of KSP/QRH Heptapeptide DimerNo drug interventionsscreening1terminated
NCT04801095
A Phase I Study of WM-S1-030 in Patients With Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT06199895
Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection in the Treatment of Patients With Taxans-resistant Pancreatic Adenocarcinoma, Cholangiocarcinoma, Lung Cancer, Gastric Cancer, Esophageal Carcinoma, or Breast Cancertreatment2recruiting
NCT02162914
Regorafenib Versus Placebo to Treat Cholangiocarcinomatreatment2unknown_status
NCT05874414
Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutation Cholangiocarcinomatreatment1 / 2recruiting
NCT02456714
Second Line Chemotherapy FOLFIRINOX in Irresectable CholangiocarcinomaNo drug interventionstreatment2completed
NCT06342414
An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT01773655
Clinical and Histopathologic Characteristics of BAP1 MutationsNo drug interventionsNot AvailableNot Availablecompleted
NCT03329950
A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignanciestreatment1completed
NCT05489250
The PLATON NetworkNo drug interventionsNot AvailableNot Availablerecruiting
NCT05957250
[68Ga]Ga-FAPI-46 Positron Emission Tomography (PET) Scan to Improve the Imaging of Pancreatic and Bile Duct CancerNo drug interventionsdiagnosticNot Availablerecruiting
NCT06530823
Pemigatinib Combined With Durvalumab for Previously Treated Biliary Tract Carcinomatreatment2not_yet_recruiting
NCT00041808
Magnetic-Targeted Doxorubicin in Treating Patients With Cancer Metastatic to the Livertreatment1 / 2completed
NCT04430738
Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancerstreatment1 / 2active_not_recruiting
NCT02683538
Radiofrequency Ablation Using Octopus Electrodes for Treatment of Focal Liver MalignanciesNo drug interventionstreatment2completed
NCT05124743
HLA Typing & Tumor Neoantigen Identification for Phase I/II Study of Autologous TCR-T Cells in Subjects With Solid TumorsNo drug interventionsNot AvailableNot Availablesuspended
NCT00414843
Storage of Bile From Routine Procedures to Study Risk FactorsNo drug interventionsNot AvailableNot Availableterminated
NCT01320254
PiCCA Study (Panitumumab in Combination With Cisplatin/Gemcitabine)treatment2completed