Kaposi's Sarcoma (DBCOND0028170)

Identifiers

Synonyms
Kaposi Sarcoma (KS) / Kaposi's sarcomas / Kaposi Sarcoma / Kaposi's sarcoma / Sarcoma, Kaposi / Kaposi's sarcoma, unspecified / Kaposi sarcoma (morphologic abnormality) / Kaposi's sarcoma (disorder) / Multiple idiopathic hemorrhagic sarcoma / Multiple idiopathic haemorrhagic sarcoma / Kaposi's sarcoma NOS / Multiple haemorrhagic sarcoma / Multiple hemorrhagic sarcoma / Kaposi's sarcoma epidemic type / Kaposi's sarcoma AIDS related / Kaposi's sarcoma with acquired immunodeficiency syndrome (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Interferon alfa-2a
A form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
Interferon alfa-2b
A form of recombinant human interferon used to treat hepatitis B and C infection, genital warts, hairy cell leukemia, follicular lymphoma, malignant melanoma, and AIDs-related Kaposi's sarcoma.
Paclitaxel
A taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.
Pomalidomide
A thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma.
Vinblastine
A vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
Vincristine
A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01764360
Strategies to Improve Kaposi Sarcoma (KS) Outcomes in ZimbabweNo drug interventionstreatmentNot Availablecompleted
NCT00339937
Studies of Human Herpesvirus 8 and Kaposi's Sarcoma in SicilyNo drug interventionsNot AvailableNot Availablecompleted
NCT01067690
Treatment With Indinavir and Chemotherapy for Advanced Classical Kaposi's Sarcomatreatment2completed
NCT00026793
Assessment of Blood Vessel Density in Kaposi's Sarcoma LesionsNo drug interventionsNot AvailableNot Availablecompleted
NCT00581815
Spectroscopy With Surface Coils and DecouplingNo drug interventionsdiagnostic1completed
NCT00380770
HIV/AIDS Kaposis Sarcoma: Comparison of Response to HAART vs HAART Plus CXTNo drug interventionstreatment4completed
NCT00686842
PTC299 in Treating Patients With HIV-Related Kaposi Sarcomatreatment1 / 2terminated
NCT01352117
Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's Sarcomatreatment3completed
NCT03300830
Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT02201420
Evaluation of Tc 99m Tilmanocept Localization in Primary Cutaneous Kaposi's Sarcoma and Lymphatic Drainage by SPECT/CTdiagnostic2completed
NCT00001560
Clinical, Laboratory and Epidemiologic Pilot Studies of Individuals at High Risk for Viral-Associated CancersNo drug interventionsNot AvailableNot Availablecompleted
NCT00001294
Genetic Factors and Interrelationships for Sexual Orientation, Susceptibility to HIV and Kaposi's Sarcoma, Alcoholism and Psychological Traits, and Histocompatibility AntigensNo drug interventionsNot AvailableNot Availablecompleted
NCT00444379
Anti-Retrovirals for Kaposi's Sarcomatreatment4completed
NCT00026728
Seroprevalence of Kaposi's Sarcoma Herpes Virus in the United StatesNo drug interventionsNot AvailableNot Availablecompleted
NCT00006171
Effects of Potent Antiretroviral Therapy on Kaposi s SarcomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01296815
Intralesional Bevacizumab for Treating AIDS-associated KaposiĀ“s Sarcoma of the Larynx, Pharynx and Oral Cavitytreatment2completed
NCT00055237
Bevacizumab to Treat Kaposi's Sarcoma in HIV-Positive and HIV-Negative Patientstreatment2completed
NCT00982449
124I-FIAU Imaging in EBV and KSHV Associated CancersNo drug interventionsbasic_scienceNot Availablecompleted
NCT01276236
Effects of Maraviroc (MVC) on HIV-related Kaposi's Sarcoma (KS)treatment2completed
NCT00006518
Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT00001535
Twins Study of Gene Therapy for HIV Infectiontreatment1completed
NCT02212639
Phase II Multicentric Study of Digoxin Per os in Classic or Endemic Kaposi' s Sarcomatreatment2unknown_status
NCT02029430
A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's Sarcomatreatment2completed
NCT00339326
Risk Factors for Non-HIV-Related Kaposi s SarcomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00540566
Optical Biopsy of Human Skin in Conjunction With Laser TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT00287495
BAY 43-9006 (Sorafenib) to Treat Patients With Kaposi's Sarcomatreatment1terminated
NCT04742387
Assessment of Bone Mineral Density in People Living With HIV and KSHV Associated Malignancies: A Retrospective Longitudinal AnalysisNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04902443
Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIVtreatment1recruiting
NCT04941274
Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcomatreatment1 / 2recruiting
NCT06375122
Natural History Study of Kaposi SarcomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT06445166
Propranolol for the Treatment of Kaposi Sarcoma in Adultstreatment2not_yet_recruiting
NCT00000987
A Study of Chemotherapy Plus Azidothymidine in the Treatment of Kaposi's Sarcoma in Patients With AIDStreatment1completed
NCT00000954
A Study of Chemotherapy Plus ddI or ddC in the Treatment of AIDS-Related Kaposi's Sarcomatreatment1completed
NCT00002105
Randomized, Comparative Trial of DOX-SL (Stealth Liposomal Doxorubicin Hydrochloride) Versus Bleomycin and Vincristine in the Treatment of AIDS-Related Kaposi's Sarcomatreatment3completed
NCT00002188
A Study of ALRT1057 in Patients With AIDS-Related Kaposi's Sarcomatreatment2completed
NCT00000807
Phase II Evaluation of Low-Dose Oral Etoposide for the Treatment of Relapsed or Progressed AIDS-Related Kaposi's Sarcoma After Systemic Chemotherapytreatment2completed
NCT00002318
A Comparison of DOX-SL Versus Adriamycin Plus Bleomycin Plus Vincristine in the Treatment of Severe AIDS-Related Kaposi's Sarcomatreatment3unknown_status
NCT00002319
A Study of DOX-SL in the Treatment of AIDS-Related Kaposi's Sarcomatreatment3completed
NCT02080416
Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumorstreatment0terminated
NCT00000725
A Phase I Study of AZT and Human Interferon Alpha (Recombinant Alpha-2A and Lymphoblastoid) in the Treatment of AIDS-Associated Kaposi's Sarcomatreatment1completed
NCT02659930
Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcomatreatment1active_not_recruiting
NCT00002366
The Safety and Effectiveness of Ritonavir in the Treatment of HIV-Related Kaposi's Sarcomatreatment2completed
NCT03316274
Intra-lesional Nivolumab Therapy for Limited Cutaneous Kaposi Sarcomatreatment0completed
NCT00001120
A Study of Patients With AIDS SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT00002131
A Pilot Study of OPC-8212 (Vesnarinone) in Persons With AIDS-Related Kaposi's Sarcomatreatment2completed
NCT06480773
Kaposi Sarcoma Chemotherapy and Research (KS-CARE)No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT00000660
Phase I Study of Weekly Oral VP-16 for AIDS-Associated Kaposi's Sarcomatreatment1completed
NCT04305691
Trial of Ixazomib for Kaposi Sarcomatreatment2recruiting
NCT00002262
A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's SarcomaNo drug interventionstreatment1completed
NCT00002189
Paclitaxel in Advanced Refractory Kaposi's Sarcoma (AIDS-KS): A Phase II Trial of Paclitaxel From Baker Norton Pharmaceuticalstreatment2completed
NCT05329792
L19IL2/L19TNF in Skin Cancer Patientstreatment2recruiting
NCT00002167
Photodynamic Therapy Clinical Trial For Cutaneous AIDS-Related Kaposi's Sarcoma Study Summary.treatment2completed
NCT03157167
An Evaluation of Tc 99m Tilmanocept by Intravenous (IV) and Subcutaneous (SC) Injection in Kaposi Sarcoma (KS)diagnostic1completed
NCT00002212
A Study of Targretin Capsules in Patients With AIDS-Related Kaposi's Sarcomatreatment2completed
NCT00000681
A Phase I Study of the Combination of Recombinant GM-CSF, AZT, and Chemotherapy (ABV) (Adriamycin, Bleomycin, Vincristine) in AIDS and Kaposi's Sarcomatreatment1completed
NCT02229981
Early Phase Evaluation of ABC294640 in Patients With Refractory/Relapsed Diffuse Large B-cell Lymphoma or Kaposi Sarcomatreatment1 / 2withdrawn
NCT05663502
Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related CancersNo drug interventionsNot AvailableNot Availablerecruiting
NCT04028479
The Registry of Oncology Outcomes Associated With Testing and TreatmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT00000687
Phase II Study of Zidovudine and Recombinant Alpha-2A Interferon in the Treatment of Patients With AIDS-Associated Kaposi's Sarcomatreatment2completed
NCT03296553
Impact of Valganciclovir on Severe IRIS-Kaposi Sarcoma Mortality: an Open-label, Parallel, Randomized Controlled-trial.treatment2completed
NCT00002153
Topical Use of 4,4'-Dihydroxybenzophenone-2,4-Dinitrophenylhydrazone (A-007) in the Treatment of Advanced Malignancies Including Kaposi's Sarcoma and Lymphoproliferative Disorderstreatment1completed
NCT00002147
Use of Stealth Liposomal Doxorubicin HCl ( DOX-SL ) in the Treatment of Moderate to Severe AIDS-Related Kaposi's Sarcoma.treatment3completed
NCT00002445
Safety and Effectiveness of an Experimental Drug, IM862, in Treating Kaposi's Sarcoma in AIDS Patientstreatment3completed
NCT01495598
Pomalidomide for Kaposi Sarcoma in People With or Without HIVtreatment1 / 2completed
NCT03404297
Compression Therapy for Leg Ulcers and Kaposi Sarcoma in Western KenyaNo drug interventionstreatmentNot Availablecompleted
NCT00051597
A Safety/Efficacy Study of SGN-30 (Antibody) in Patients With Refractory or Recurrent CD30+ Hematologic Malignanciestreatment1 / 2completed
NCT03160183
Investigating Chemotherapy Treatments, Response and Subsets of HIV-associated Kaposi Sarcoma in MalawiNo drug interventionsNot AvailableNot Availablecompleted
NCT02408861
Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgerytreatment1recruiting
NCT06004011
AYAHIV Role-based Responsibilities for Oncology-focused Workforce (ARROW)No drug interventionsscreeningNot Availablerecruiting
NCT00002093
A Randomized Phase III Clinical Trial of Daunoxome Versus Combination Chemotherapy With Adriamycin/Bleomycin/Vincristine (ABV) in the Treatment of HIV-Associated Kaposi's Sarcoma.treatment3completed
NCT00395278
Development of Serologic Assays for Human Herpes Virus-8No drug interventionsNot AvailableNot Availablecompleted
NCT03050788
Smartphone Confocal Microscopy for Diagnosing Kaposi's SarcomaNo drug interventionsdiagnosticNot Availablecompleted
NCT00002185
A Pilot, Open-Label, Phase II, Randomized Study to Determine the Effects of Viracept on the Outcome of Cutaneous and Mucosal KS in AIDS Patients With CD4 <= 500 Cells/mm3treatment2completed
NCT01412515
A Phase II Study With Tumor Molecular Pharmacodynamic (MPD) Evaluation of Oral mTOR-inhibitor Everolimus (RAD001) 10 mg Daily in Patients Suffering From Classic or Endemic Kaposi's Sarcomatreatment2terminated
NCT00002137
A Phase I Trial of Tecogalan Sodium ( DS-4152 ) Administered as an Infusion Weekly x 4No drug interventionstreatment1completed
NCT05411237
Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi Sarcomatreatment3not_yet_recruiting
NCT04065152
Phase II Multicenter Study of Talimogene Laherparepvec in Classic or Endemic Kaposi Sarcomatreatment2unknown_status
NCT00001059
Comparison of Liposomal Doxorubicin Used Alone or in Combination With Bleomycin Plus Vincristine in the Treatment of Kaposi's Sarcoma in Patients With AIDStreatment2completed
NCT00002259
Phase II Study of Intravenous Novantrone(R) in the Treatment of AIDS Related Kaposi's Sarcomatreatment2completed
NCT00002342
A Study of Tecogalan SodiumNo drug interventionstreatment1completed
NCT03993106
A Study of sEphB4-HSA in Kaposi Sarcomatreatment2recruiting
NCT00923936
Pilot Study of Liposomal Doxorubicin Combined With Bevacizumab Followed by Bevacizumab Monotherapy in Adults With Advanced Kaposi s Sarcomatreatment2completed
NCT00002136
A Phase I Trial of Tecogalan Sodium (DS-4152) Administered as an Infusion Every 21 DaysNo drug interventionstreatment1completed
NCT00001113
A Study of AZT Plus Human Interferon Alpha in the Treatment of AIDS-Related Kaposi's Sarcomatreatment1completed
NCT04893018
NT-I7 for Kaposi Sarcoma in Patients With or Without HIVtreatment1terminated
NCT05081141
HHV8 and Solid Organ TransplantationNo drug interventionsNot AvailableNot Availablerecruiting
NCT04303117
NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcomatreatment1 / 2recruiting
NCT05846724
Pembrolizumab Plus Lenvatinib in Previously Treated Classic Kaposi Sarcomatreatment2not_yet_recruiting
NCT00000996
A Study of Doxorubicin in the Treatment of AIDS-Related Kaposi's Sarcomatreatment2completed
NCT00000763
A Phase I Study of TNP-470 in the Treatment of AIDS-Associated Kaposi's Sarcomatreatment1completed
NCT00002439
A Study of ALRT 1057 Topical Gel in Patients With AIDS-Related Kaposi's SarcomatreatmentNot Availablecompleted
NCT00002226
Safety and Effectiveness of Giving SU5416 to HIV-Infected Patients With AIDS-Related Kaposi's SarcomatreatmentNot Availablecompleted
NCT02595866
Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancertreatment1completed
NCT05859074
A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancertreatment1active_not_recruiting
NCT00005931
SU5416 in Patients With AIDS-Related Kaposi's Sarcoma Who Have Not Responded to Treatmenttreatment2completed
NCT00000694
A Phase I Trial of Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (rHuGM-CSF), Recombinant Alpha Interferon and Azidothymidine (AZT) in AIDS-Associated Kaposi's Sarcomatreatment1completed
NCT05797662
A Study of Propranolol to Treat Kaposi Sarcomatreatment2not_yet_recruiting
NCT03469804
Phase II Multicentric Study of Pembrolizumab in Classic or Endemic Kaposi's Sarcomatreatment2unknown_status
NCT00000769
A Phase I/II Study of Recombinant Interleukin-4 in AIDS and Kaposi's Sarcomatreatment1completed
NCT00006310
KSHV Infection in Blood Donors From TexasNo drug interventionsNot AvailableNot Availablecompleted
NCT00000695
Open Label Phase I Study To Evaluate the Safety of Combination Therapy With AZT and Interferon-Beta in Patients With AIDS Related Kaposi's Sarcomatreatment1completed
NCT00001114
The Safety and Effectiveness of Interferon Alfa-2B Plus Didanosine in Patients With Kaposi's Sarcomatreatment2completed
NCT00002314
A Study of Ro 24-7429 in Patients With HIV-Related Kaposi's Sarcomatreatment2completed
NCT00002138
A Phase I Trial of Tecogalan Sodium ( DS-4152 ) Administered as an Infusion Twice Weekly for 21 Days.No drug interventionstreatment1completed