Vaginal Candidiasis

Also known as: Candida Vulvovaginitis / Vaginal Candida / Vaginal moniliasis / Candidal Vulvovaginitis / Vaginal yeast infection / Candida vaginitis / Candida vaginal / Vaginal candidiasis (disorder) / Vaginitis, Monilial / Thrush vaginal / Candidiasis of vagina (disorder) / Yeast vaginitis / Moniliasis vaginal / Vaginal Yeast Infections / Vulvovaginal candidiasis / Candidiasis, Vulvovaginal / Candidal vulvovaginitis (disorder) / Vulvovaginal candida / Candidiasis of vulva and vagina / Candidal vulvovaginitis NOS (disorder) / Candidal: [vulvovaginitis NOS] or [cervix] / Vulvovaginal mycotic infection

DrugDrug NameDrug Description
DB01190ClindamycinA lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.
DB00257ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
DB09115DiiodohydroxyquinolineUsed in the treatment of amoebiasis.
DB13434FenticonazoleAn imidazole antifungal used to treat a variety of topical fungal infections.
DB00196FluconazoleA triazole antifungal used to treat various fungal infections including candidiasis.
DB01026KetoconazoleA broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
DB13633MepartricinA medication indicated in the treatment of benign prostatic hyperplasia, vaginal candidiasis, or trichomoniasis.
DB00916MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
DB01110MiconazoleAn azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
DB13724NifuratelA nitrofuran derivative indicated in the treatment of leucorrhea, vulvovaginal infections, and urinary tract infections.
DB00646NystatinA polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species.
DB00911TinidazoleA nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.
DB01007TioconazoleAn imidazole antifungal used to treat vulvovaginal candidiasis.
DrugDrug NameTargetType
DB01190ClindamycinCytochrome P450 3A4enzyme
DB01190ClindamycinCytochrome P450 3A5enzyme
DB01190ClindamycinAlpha-1-acid glycoprotein 1carrier
DB01190ClindamycinP-glycoprotein 1transporter
DB01190Clindamycin50S ribosomal protein L1target
DB00257ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB00257ClotrimazoleCytochrome P450 2D6enzyme
DB00257ClotrimazoleCytochrome P450 2C8enzyme
DB00257ClotrimazoleCytochrome P450 3A4enzyme
DB00257ClotrimazoleCytochrome P450 2B6enzyme
DB00257ClotrimazoleP-glycoprotein 1transporter
DB00257ClotrimazoleCytochrome P450 2A6enzyme
DB00257ClotrimazoleCytochrome P450 2C9enzyme
DB00257ClotrimazoleCytochrome P450 2E1enzyme
DB00257ClotrimazoleCytochrome P450 3A7enzyme
DB00257ClotrimazoleCytochrome P450 51target
DB00257ClotrimazoleNuclear receptor subfamily 1 group I member 2target
DB00257ClotrimazoleHydroxycarboxylic acid receptor 2target
DB00257ClotrimazoleBile salt export pumptransporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
DB00257ClotrimazoleErgosteroltarget
DB00196FluconazoleCytochrome P450 3A4enzyme
DB00196FluconazoleCytochrome P450 2C9enzyme
DB00196FluconazoleCytochrome P450 2C19enzyme
DB00196FluconazoleP-glycoprotein 1transporter
DB00196FluconazoleCytochrome P450 51target
DB00196FluconazoleCytochrome P450 3A5enzyme
DB01026KetoconazoleCytochrome P450 3A4enzyme
DB01026KetoconazoleCytochrome P450 2C9enzyme
DB01026KetoconazoleCytochrome P450 2C19enzyme
DB01026KetoconazoleCytochrome P450 3A5enzyme
DB01026KetoconazoleCytochrome P450 1A2enzyme
DB01026KetoconazoleCytochrome P450 2C8enzyme
DB01026KetoconazoleCytochrome P450 1A1enzyme
DB01026KetoconazoleCytochrome P450 2D6enzyme
DB01026KetoconazoleBile salt export pumptransporter
DB01026KetoconazoleP-glycoprotein 1transporter
DB01026KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 1B1enzyme
DB01026KetoconazoleCytochrome P450 2A6enzyme
DB01026KetoconazoleCytochrome P450 2B6enzyme
DB01026KetoconazoleLanosterol 14-alpha demethylasetarget
DB01026KetoconazoleAndrogen receptortarget
DB01026KetoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB01026KetoconazoleSteroid 21-hydroxylasetarget
DB01026KetoconazolePotassium voltage-gated channel subfamily H member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 3target
DB01026KetoconazoleUDP-glucuronosyltransferase 1-1enzyme
DB01026KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
DB01026KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
DB01026KetoconazoleCytochrome P450 4F12enzyme
DB01026KetoconazoleLeukotriene-B(4) omega-hydroxylase 1enzyme
DB01026KetoconazoleSerum albumincarrier
DB01026KetoconazoleSex hormone-binding globulincarrier
DB01026KetoconazoleCytochrome P450 19A1enzyme
DB01026KetoconazoleUDP-glucuronosyltransferase 1-7enzyme
DB00916MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
DB00916MetronidazoleCytochrome P450 2C9enzyme
DB00916MetronidazoleCytochrome P450 3A4enzyme
DB00916MetronidazoleCytochrome P450 2C8enzyme
DB00916MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
DB00916MetronidazoleAnaerobic bacterial DNAtarget
DB00916MetronidazoleProtozoal DNAtarget
DB00916MetronidazoleP-glycoprotein 1transporter
DB00916MetronidazoleCytochrome P450 2A6enzyme
DB00916MetronidazoleCytochrome P450 3A5enzyme
DB00916MetronidazoleCytochrome P450 3A7enzyme
DB01110MiconazoleCytochrome P450 2C9enzyme
DB01110MiconazoleCytochrome P450 2D6enzyme
DB01110MiconazoleCytochrome P450 3A4enzyme
DB01110MiconazoleP-glycoprotein 1transporter
DB01110MiconazoleCytochrome P450 51target
DB01110MiconazoleNitric oxide synthase, endothelialtarget
DB01110MiconazoleNitric oxide synthase, inducibletarget
DB01110MiconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01110MiconazoleCytochrome P450 2A6enzyme
DB01110MiconazoleCytochrome P450 2B6enzyme
DB01110MiconazoleCytochrome P450 2C19enzyme
DB01110MiconazoleCytochrome P450 2E1enzyme
DB01110MiconazoleNuclear receptor subfamily 1 group I member 2target
DB01110MiconazoleLanosterol 14-alpha demethylaseenzyme
DB01110MiconazoleCytochrome P450 19A1enzyme
DB01110MiconazoleCalcium-activated potassium channeltarget
DB01110MiconazoleVoltage-gated Potassium Channelstarget
DB01110MiconazoleInward rectifier potassium channeltarget
DB01110MiconazoleVoltage gated L-type calcium channeltarget
DB01110MiconazoleSerum albumincarrier
DB01110MiconazoleCytochrome P450 2C8enzyme
DB00646NystatinErgosteroltarget
DB00646NystatinSolute carrier organic anion transporter family member 1B1transporter
DB00646NystatinSolute carrier organic anion transporter family member 1B3transporter
DB00911TinidazoleCytochrome P450 3A4enzyme
DB00911TinidazoleDNAtarget
DB00911TinidazoleBile salt export pumptransporter
DB01007TioconazoleLanosterol 14-alpha demethylasetarget
DB01007TioconazoleCytochrome P450 19A1enzyme
DB01007TioconazoleCytochrome P450 2C19enzyme
DB01007TioconazoleCytochrome P450 2E1enzyme
DB01007TioconazoleCytochrome P450 3A4enzyme
DB01007TioconazoleCytochrome P450 51target
DrugDrug NamePhaseStatusCount
DB14224Lactobacillus reuteri1Unknown Status1
DB00681Amphotericin B2Completed1
DB00681Amphotericin B2Withdrawn1
DB00196Fluconazole2Completed2
DB12471Ibrexafungerp2Completed1
DB12471Ibrexafungerp3Completed2
DB01026Ketoconazole3Unknown Status1
DB00251Terconazole3Unknown Status1
DB00257ClotrimazoleNot AvailableCompleted1
DB00916MetronidazoleNot AvailableCompleted1
DB01110MiconazoleNot AvailableCompleted1