Urticaria

Also known as: Hives / Urticaria NOS / Urticarias / (Angioneurotic oedema) or (urticaria) / Urtication / Urticated rash / Urticarial / Urticarial rash / Rash urticarial / (Urticaria NOS) or (hives) / Urticaria (morphologic abnormality) / Urticaria (disorder) / Unspecified urticaria / Urticaria, unspecified / Wheal (finding) / Urticaria NOS (disorder) / (Urticaria NOS) or (hives) or (pachydermia)

DrugDrug NameDrug Description
DB13501BendazacA non-steroidal anti-inflammatory drug (NSAID) available as an eye drop for the treatment of cataracts and as a topical cream for the treatment of dermatitis, eczema, hives, skin ulcers and other inflammatory skin conditions.
DB00748CarbinoxamineA first generation antihistamine used to treat allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, allergic reactions, and mild allergic reactions.
DB01114ChlorpheniramineA histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
DB09007ChlorphenoxamineAn antihistamine used as an antipruritic.
DB00283ClemastineAn antihistamine with sedative and anticholinergic effects used to treat the symptoms of allergic rhinitis.
DB13679DexchlorpheniramineA chlorpheniramine enantiomer antihistamine indicated in the treatment of sunburns, insect bites, and allergic reactions of the skin.
DB09555Dexchlorpheniramine maleateA first generation antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema.
DB09357DexpanthenolAn alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN).
DB01075DiphenhydramineA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
DB00668EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
DB00874GuaifenesinAn expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses.
DB06691MepyramineAn antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders.
DB12523MizolastineA second-generation non-sedating antihistamine used to treat symptoms of allergic rhinoconjunctivitis and urticaria.
DB01620PheniramineAn antihistamine used to treat allergic rhinitis and pruritus.
DB11614RupatadineA selective histamine H1 receptor antagonist and platelet activating factor (PAF) antagonist used to treat allergic rhinitis.
DB00620TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
DrugDrug NameTargetType
DB13501BendazacFree radicalstarget
DB13501BendazacProstaglandin G/H synthase 1target
DB13501BendazacProstaglandin G/H synthase 2target
DB00748CarbinoxamineHistamine H1 receptortarget
DB01114ChlorpheniramineHistamine H1 receptortarget
DB01114ChlorpheniramineCytochrome P450 3A4enzyme
DB01114ChlorpheniramineCytochrome P450 2D6enzyme
DB01114ChlorpheniramineSodium-dependent serotonin transportertarget
DB01114ChlorpheniramineSodium-dependent noradrenaline transportertarget
DB01114ChlorpheniramineSodium-dependent dopamine transportertarget
DB01114ChlorpheniramineCytochrome P450 3A5enzyme
DB01114ChlorpheniramineCytochrome P450 3A7enzyme
DB01114ChlorpheniramineSolute carrier family 22 member 2transporter
DB01114ChlorpheniramineSolute carrier family 22 member 1transporter
DB00283ClemastineHistamine H1 receptortarget
DB00283ClemastineCytochrome P450 2D6enzyme
DB13679DexchlorpheniramineCytochrome P450 2D6enzyme
DB09555Dexchlorpheniramine maleateCytochrome P450 2D6enzyme
DB09555Dexchlorpheniramine maleateHistamine H1 receptortarget
DB09555Dexchlorpheniramine maleateSolute carrier family 22 member 1carrier
DB09555Dexchlorpheniramine maleateSolute carrier family 22 member 2carrier
DB09555Dexchlorpheniramine maleateCytochrome P450 3A4enzyme
DB01075DiphenhydramineHistamine H1 receptortarget
DB01075DiphenhydramineCytochrome P450 2D6enzyme
DB01075DiphenhydramineCytochrome P450 2C9enzyme
DB01075DiphenhydramineCytochrome P450 2C19enzyme
DB01075DiphenhydramineSolute carrier family 22 member 2transporter
DB01075DiphenhydramineSolute carrier family 22 member 5transporter
DB01075DiphenhydramineProstaglandin G/H synthase 1enzyme
DB01075DiphenhydramineMuscarinic acetylcholine receptor M2target
DB00668EpinephrineAlpha-1A adrenergic receptortarget
DB00668EpinephrineBeta-1 adrenergic receptortarget
DB00668EpinephrineBeta-2 adrenergic receptortarget
DB00668EpinephrineSolute carrier family 22 member 2transporter
DB00668EpinephrineSolute carrier family 22 member 1transporter
DB00668EpinephrineCytochrome P450 2C9enzyme
DB00668EpinephrineCytochrome P450 3A4enzyme
DB00668EpinephrineAlpha-1B adrenergic receptortarget
DB00668EpinephrineAlpha-1D adrenergic receptortarget
DB00668EpinephrineAlpha-2A adrenergic receptortarget
DB00668EpinephrineAlpha-2B adrenergic receptortarget
DB00668EpinephrineTumor necrosis factortarget
DB00668EpinephrineCatechol O-methyltransferaseenzyme
DB00668EpinephrineMonoamine oxidaseenzyme
DB00874GuaifenesinNMDA receptortarget
DB06691MepyramineCytochrome P450 2D6enzyme
DB06691MepyramineHistamine H1 receptortarget
DB06691MepyramineSolute carrier family 22 member 4transporter
DB06691MepyramineSolute carrier family 22 member 5transporter
DB12523MizolastineCytochrome P450 2D6enzyme
DB01620PheniramineHistamine H1 receptortarget
DB01620PheniramineNuclear receptor subfamily 1 group I member 3target
DB01620PheniramineHistamine H4 receptortarget
DB11614RupatadineCytochrome P450 3A4enzyme
DB11614RupatadineCytochrome P450 2C9enzyme
DB11614RupatadineCytochrome P450 2C19enzyme
DB11614RupatadineCytochrome P450 2D6enzyme
DB11614RupatadinePlatelet-activating factor receptortarget
DB11614RupatadineHistamine H1 receptortarget
DB00620TriamcinoloneCorticosteroid-binding globulincarrier
DB00620TriamcinoloneGlucocorticoid receptortarget
DB00620TriamcinoloneCytochrome P450 3A4enzyme
DB00620TriamcinoloneProstaglandin G/H synthase 2enzyme
DB00620TriamcinoloneCholinesteraseenzyme
DB00620TriamcinoloneCytochrome P450 3A5enzyme
DB00620TriamcinoloneCytochrome P450 3A7enzyme
DB00620TriamcinoloneSerum albumincarrier
DrugDrug NamePhaseStatusCount
DB04890Bepotastine1Completed1
DB09321Zinc oxide1Completed1
DB01281Abatacept1 / 2Completed1
DB00026Anakinra1 / 2Terminated1
DB00073Rituximab1 / 2Terminated1
DB06168Canakinumab2Completed1
DB00254Doxycycline2Recruiting1
DB14785Fenebrutinib2Completed1
DB14785Fenebrutinib2Terminated1
DB05381Histamine2Terminated1
DB00563Methotrexate2Terminated1
DB00043Omalizumab2Completed1
DB11058Petrolatum2Recruiting1
DB15176Quilizumab2Completed1
DB11614Rupatadine2Terminated1
DB09321Zinc oxide2Recruiting1
DB11591Bilastine3Completed1
DB00169Cholecalciferol3Unknown Status1
DB00967Desloratadine3Completed2
DB06282Levocetirizine3Completed2
DB06282Levocetirizine3Recruiting1
DB14646Prednisone acetate3Recruiting1
DB11614Rupatadine3Terminated1
DB11591Bilastine4Completed2
DB00341Cetirizine4Completed2
DB00341Cetirizine4Terminated1
DB00250Dapsone4Unknown Status1
DB00967Desloratadine4Completed5
DB00967Desloratadine4Terminated1
DB11742Ebastine4Completed1
DB00950Fexofenadine4Completed1
DB06282Levocetirizine4Enrolling by Invitation1
DB06282Levocetirizine4Unknown Status1
DB00043Omalizumab4Completed1
DB00043Omalizumab4Withdrawn1
DB00169CholecalciferolNot AvailableCompleted1
DB00967DesloratadineNot AvailableCompleted3
DB01234DexamethasoneNot AvailableCompleted1
DB00751EpinastineNot AvailableCompleted1
DB06282LevocetirizineNot AvailableTerminated1
DB00455LoratadineNot AvailableCompleted1
DB00043OmalizumabNot AvailableUnknown Status1
DB00860PrednisoloneNot AvailableCompleted1
DB14631Prednisolone phosphateNot AvailableCompleted1