Ringworm (DBCOND0043009)

Identifiers

Synonyms

Dermatophytosis, unspecified / Tinea NOS / Dermatophytosis (disorder) / Tinea / Tinea infections / Tinea infection NOS / Tinea infection / Ringworm NOS / Dermatophytosis / Dermatophytosis of unspecified site / Dermatophytosis NOS

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Benzoic acid	An antimicrobial food additive.	Cocaine esterasetarget D-amino-acid oxidasetarget Chlorocatechol 1,2-dioxygenasetarget 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget Non-heme chloroperoxidasetarget Oxygen-insensitive NAD(P)H nitroreductasetarget Hydroxyquinol 1,2-dioxygenasetarget Replication proteintarget Solute carrier organic anion transporter family member 2B1transporter Organic anion transporter 3transporter Monocarboxylate transporter 1transporter Solute carrier family 15 member 1target Ras-related protein Rab-9Atarget
Chlorhexidine	An antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis.	Bacterial outer membranetarget Albumincarrier
Clotrimazole	A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.	Intermediate conductance calcium-activated potassium channel protein 4target Cytochrome P450 2D6enzyme Cytochrome P450 2C8enzyme Cytochrome P450 3A4enzyme Cytochrome P450 2B6enzyme ATP-dependent translocase ABCB1transporter Cytochrome P450 2A6enzyme Cytochrome P450 2C9enzyme Cytochrome P450 2E1enzyme Cytochrome P450 3A7enzyme Lanosterol 14-alpha demethylasetarget Nuclear receptor subfamily 1 group I member 2target Hydroxycarboxylic acid receptor 2target Bile salt export pumptransporter Solute carrier organic anion transporter family member 1B1transporter Solute carrier organic anion transporter family member 1B3transporter Ergosteroltarget C-X-C chemokine receptor type 2target
Econazole	A topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.	Aromataseenzyme Cytochrome P450 2E1enzyme Cytochrome P450 3A4enzyme Lanosterol 14-alpha demethylasetarget Nuclear receptor subfamily 1 group I member 2target
Miconazole	An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.	Cytochrome P450 2C9enzyme Cytochrome P450 2D6enzyme Cytochrome P450 3A4enzyme ATP-dependent translocase ABCB1transporter Lanosterol 14-alpha demethylasetarget Nitric oxide synthase 3target Nitric oxide synthase, inducibletarget Cytochrome P450 11B1, mitochondrialenzyme Cytochrome P450 2A6enzyme Cytochrome P450 2B6enzyme Cytochrome P450 2C19enzyme Cytochrome P450 2E1enzyme Nuclear receptor subfamily 1 group I member 2target Lanosterol 14-alpha demethylaseenzyme Aromataseenzyme Calcium-activated potassium channeltarget Voltage-gated Potassium Channelstarget Inward rectifier potassium channeltarget Voltage gated L-type calcium channeltarget Albumincarrier Cytochrome P450 2C8enzyme
Phenol	An antiseptic and disinfectant used in a variety of settings.	Thermolysintarget Albumintarget Carbonic anhydrase 1target Carbonic anhydrase 4target Carbonic anhydrase 12target Carbonic anhydrase 2target Carbonic anhydrase 14target Carbonic anhydrase 9target
Tolnaftate	An antifungal agent used to treat various skin infections caused by fungi.	Squalene monooxygenasetarget Squalene monooxygenasetarget
Undecylenic acid	An antifungal used to treat tinea species infections.	Calpain-1 catalytic subunittarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT00856596	Once a Day Topical Treatment for Athlete's Foot Fungus Inbetween the Toes in Males and Females	No drug interventions	treatment	3	unknown_status