Intraabdominal Infections

Also known as: Intra Abdominal Infections / Infection, Intra-abdominal / Intra abdominal infection / Intra-Abdominal Infections / Intra-Abdominal Infection / Abdominal infection / Infectious disease of abdomen (disorder)

DrugDrug NameDrug Description
DB00479AmikacinAn aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria.
DB00355AztreonamA beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria.
DB01329CefoperazoneA broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts.
DB01330CefotetanAn antibiotic medication used for the prophylaxis and treatment of various bacterial infections, including urinary tract infections, bone and joint infection, and lower respiratory tract infections.
DB01331CefoxitinA semi-synthetic, broad-spectrum antibiotic for parenteral administration used for the treatment of serious bacterial infections, such as urinary tract infection, blood infection, bone and joint infection, and lower respiratory tract infection.
DB00438CeftazidimeAn injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others.
DB01212CeftriaxoneA broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract.
DB01597CilastatinA renal dehydropeptidase inhibitor used to prevent degradation of imipenem. Both medications are used together to treat a variety of infections.
DB00766Clavulanic acidA beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics.
DB12329EravacyclineA tetracycline antibiotic used to treat complicated intra-abdominal infections.
DB01598ImipenemA carbapenem antibiotic normally administered with cilastatin to treat a variety of infections.
DB00319PiperacillinA penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam­ susceptible, β-lactamase generating strains of several bacteria.
DB09324SulbactamAn beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections.
DB00684TobramycinAn aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections.
DrugDrug NameTargetType
DB00479Amikacin30S ribosomal protein S12target
DB00355AztreonamPenicillin-binding protein 3target
DB00355AztreonamBeta-lactamasetarget
DB01329CefoperazoneSerum albumincarrier
DB01329CefoperazoneSolute carrier family 22 member 6transporter
DB01329CefoperazoneSolute carrier family 22 member 8transporter
DB01329CefoperazoneSolute carrier family 22 member 11transporter
DB01329CefoperazoneSolute carrier family 22 member 7transporter
DB01329CefoperazonePeptidoglycan synthase FtsItarget
DB01329CefoperazonePenicillin-binding protein 1Btarget
DB01329CefoperazonePenicillin-binding protein 2target
DB01329CefoperazonePenicillin-binding protein 1Atarget
DB01329CefoperazoneD-alanyl-D-alanine carboxypeptidase DacCtarget
DB01329CefoperazoneD-alanyl-D-alanine carboxypeptidase DacAtarget
DB01329CefoperazoneD-alanyl-D-alanine carboxypeptidase DacBtarget
DB01329CefoperazonePenicillin-binding protein 1Atarget
DB01329CefoperazonePenicillin-binding protein 1Btarget
DB01330CefotetanSerum albumincarrier
DB01330CefotetanPenicillin-binding protein 3target
DB01331CefoxitinPenicillin-binding protein 1Atarget
DB01331CefoxitinPenicillin-binding protein 1Btarget
DB01331CefoxitinPeptidoglycan synthase FtsItarget
DB01331CefoxitinD-alanyl-D-alanine carboxypeptidase DacAtarget
DB01331CefoxitinD-alanyl-D-alanine carboxypeptidase DacBtarget
DB01331CefoxitinD-alanyl-D-alanine carboxypeptidase DacCtarget
DB01331CefoxitinD-alanyl-D-alanine endopeptidasetarget
DB01331CefoxitinBeta-lactamaseenzyme
DB01331CefoxitinPenicillin-binding protein 3target
DB01331CefoxitinPenicillin-binding protein 1btarget
DB01331CefoxitinPenicillin-binding protein 2atarget
DB01331CefoxitinPenicillin-binding protein 1Atarget
DB01331CefoxitinPenicillin-binding protein 2Btarget
DB00438CeftazidimeSolute carrier family 22 member 6transporter
DB00438CeftazidimePeptidoglycan synthase FtsItarget
DB00438CeftazidimePenicillin-binding protein 1Atarget
DB00438CeftazidimePenicillin-binding protein 1Btarget
DB00438CeftazidimePenicillin-binding protein 2target
DB00438CeftazidimeSerum albumincarrier
DB01212CeftriaxoneSerum albumincarrier
DB01212CeftriaxoneSolute carrier family 15 member 1transporter
DB01212CeftriaxoneSolute carrier family 15 member 2transporter
DB01212CeftriaxoneSolute carrier family 22 member 6transporter
DB01212CeftriaxoneSolute carrier family 22 member 8transporter
DB01212CeftriaxoneSolute carrier family 22 member 11transporter
DB01212CeftriaxonePenicillin-binding protein 2Btarget
DB01212CeftriaxoneGlutamine synthetaseenzyme
DB01212CeftriaxoneSolute carrier family 22 member 11target
DB01212CeftriaxoneSolute carrier family 22 member 6target
DB01212CeftriaxoneSolute carrier family 22 member 8target
DB01212CeftriaxoneSolute carrier family 15 member 1target
DB01212CeftriaxoneP-glycoprotein 1transporter
DB01597CilastatinDipeptidase 1target
DB01597CilastatinSolute carrier family 22 member 6transporter
DB01597CilastatinSolute carrier family 22 member 8transporter
DB00766Clavulanic acidBacterial beta-lactamase enzymestarget
DB00766Clavulanic acidSodium/glucose cotransporter 1transporter
DB12329EravacyclineCytochrome P450 3A4enzyme
DB12329EravacyclineAmine oxidase [flavin-containing] Aenzyme
DB12329Eravacycline30S ribosomal protein S4target
DB01598ImipenemPenicillin-binding protein 1Atarget
DB01598ImipenemPenicillin-binding protein 1Btarget
DB01598ImipenemPenicillin-binding protein 2target
DB01598ImipenemPenicillin-binding protein 3target
DB01598ImipenemDipeptidase 1enzyme
DB01598ImipenemPenicillin-binding protein 4target
DB01598ImipenemBeta-lactamase SHV-1enzyme
DB01598ImipenemBeta-lactamase TEMenzyme
DB01598ImipenemBeta-lactamase CTX-Menzyme
DB01598ImipenemBeta-lactamase (KPC-2)enzyme
DB00319PiperacillinSolute carrier family 22 member 6transporter
DB00319PiperacillinPenicillin-binding protein 3target
DB00319PiperacillinPenicillin-binding protein 2Btarget
DB00319PiperacillinPenicillin-binding protein 2atarget
DB00319PiperacillinPenicillin-binding protein 1btarget
DB00319PiperacillinSolute carrier family 22 member 8transporter
DB09324SulbactamBeta-lactamasetarget
DB00684Tobramycin16S ribosomal RNAtarget
DB00684TobramycinBacterial outer membranetarget
DB00684TobramycinCytoplasmic membranetarget
DB00684Tobramycin23S ribosomal RNAtarget
DrugDrug NamePhaseStatusCount
DB00104Octreotide1Completed1
DB15284Sulopenem1Not Yet Recruiting1
DB00760Meropenem1 / 2Completed1
DB01597Cilastatin2Completed1
DB01598Imipenem2Completed1
DB12377Relebactam2Completed1
DB00560Tigecycline2Completed1
DB01060Amoxicillin3Completed2
DB09050Ceftolozane3Completed1
DB01212Ceftriaxone3Completed3
DB00537Ciprofloxacin3Completed1
DB00766Clavulanic acid3Completed2
DB00303Ertapenem3Completed2
DB00916Metronidazole3Completed5
DB00218Moxifloxacin3Completed2
DB01032Probenecid3Completed1
DB15284Sulopenem3Completed1
DB16335Sulopenem etzadroxil3Completed1
DB01606Tazobactam3Completed1
DB00415Ampicillin4Completed2
DB09060Avibactam4Recruiting1
DB00438Ceftazidime4Recruiting1
DB01212Ceftriaxone4Completed1
DB01597Cilastatin4Completed1
DB06211Doripenem4Completed1
DB00303Ertapenem4Completed1
DB01598Imipenem4Completed1
DB00916Metronidazole4Completed1
DB00218Moxifloxacin4Completed1
DB09324Sulbactam4Completed2
DB00560Tigecycline4Completed2
DB00802AlfentanilNot AvailableCompleted1
DB00479AmikacinNot AvailableCompleted1
DB00513Aminocaproic acidNot AvailableCompleted1
DB00559BosentanNot AvailableCompleted1
DB01413CefepimeNot AvailableCompleted1
DB00369CidofovirNot AvailableCompleted1
DB00537CiprofloxacinNot AvailableCompleted1
DB00363ClozapineNot AvailableCompleted1
DB06211DoripenemNot AvailableCompleted1
DB00828FosfomycinNot AvailableCompleted1
DB00502HaloperidolNot AvailableCompleted1
DB00598LabetalolNot AvailableCompleted1
DB08815LurasidoneNot AvailableCompleted1
DB00959MethylprednisoloneNot AvailableCompleted1
DB01618MolindoneNot AvailableCompleted1
DB00607NafcillinNot AvailableCompleted1
DB01115NifedipineNot AvailableCompleted1
DB00497OxycodoneNot AvailableCompleted1
DB00312PentobarbitalNot AvailableCompleted1
DB00319PiperacillinNot AvailableCompleted1
DB00728RocuroniumNot AvailableCompleted1
DB00658SevelamerNot AvailableCompleted1
DB00421SpironolactoneNot AvailableCompleted1
DB01606TazobactamNot AvailableCompleted1
DB00560TigecyclineNot AvailableCompleted2
DB00684TobramycinNot AvailableCompleted1
DB00302Tranexamic acidNot AvailableCompleted1
DB00512VancomycinNot AvailableCompleted1
DB01339VecuroniumNot AvailableCompleted1
DB00682WarfarinNot AvailableCompleted1
DB00246ZiprasidoneNot AvailableCompleted1
DB00425ZolpidemNot AvailableCompleted1