NCT06442436
A Study of Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015) treatment 1 recruiting NCT04819464
A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics of a Single Dose of Cenerimod other 1 completed NCT05045482
Hepatic Impairment with Cirrhosis Due to Cholestatic Liver Disease treatment 1 recruiting NCT05552183
Study to Evaluate the Safety, Tolerability, and PK of Pacritinib No drug interventions treatment 1 completed NCT05564104
A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Works in Participants With Reduced Liver Function and in Healthy Participants With Normal Liver Function and How Cagrilintide is Absorbed and Used by the Body treatment 1 recruiting NCT05935033
A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Emraclidine treatment 1 recruiting NCT06048302
PK and Safety in Participants Taking Obicetrapib With Moderate Hepatic Impairment Relative to Normal Hepatic Function other 1 completed NCT06402721
A Study to Learn About How BAY 3283142 Moves Into, Through, and Out of the Body After a Single Dose in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function No drug interventions other 1 recruiting NCT06425198
Study to Assess Drug Levels and Safety of BMS-986278 in Healthy Participants and Participants With Different Degrees of Hepatic Impairment treatment 1 recruiting NCT06575959
A Clinical Study of Enlicitide Decanoate in People With Liver Function Problems (MK-0616-030) No drug interventions treatment 1 recruiting NCT06576765
Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD0780 No drug interventions treatment 1 recruiting NCT06600243
Influence of Microfiltered-seawater Supplementation and Variable Resistance Training in Blood Pressure, Oxidative Stress, Hepatic, and Renal Biomarkers in Older Women No drug interventions prevention Not Available completed NCT01767103
An Open-label, Non-randomized, Parallel Group Study in Subjects With Mild and Moderate Hepatic Insufficiency and Healthy Volunteers Not Available 4 completed NCT05478603
A Study to Understand How the Study Medicine (PF-07081532) is Processed in People With Liver Dysfunction No drug interventions basic_science 1 completed NCT04887064
Pharmacokinetics of Sotorasib in Healthy Participants and Participants With Moderate or Severe Hepatic Impairment basic_science 1 completed NCT04950764
An Open-Label Study Following Oral Dosing of Seladelpar to Subjects With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI) treatment 1 recruiting NCT04942964
A Study to Evaluate ASP0367 in Participants With Mild/Moderate Hepatic Impairment Compared to Participants With Normal Hepatic Function basic_science 1 completed NCT03369002
Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Seladelpar in Subjects With Hepatic Impairment and Healthy Subjects treatment 1 completed NCT03309202
Study of PF-05221304 in Subjects With Varying Degrees of Hepatic Impairment basic_science 1 completed NCT01863784
A Study to Evaluate the Pharmacokinetics of JNJ-38518168 in Patients With Mild and Moderate Hepatic Impairment Compared With Patients With Normal Hepatic Function treatment 1 completed NCT02372084
A Phase 1 Study of Osilodrostat (LCI699) in Healthy Volunteers and Subjects With Impaired Hepatic Function treatment 1 completed NCT00791284
A Study of the Pharmacokinetics of Paliperidone in Volunteers With Normal or Impaired Liver Function treatment 1 completed NCT02245243
Pharmacokinetics of Delafloxacin in Subjects With and Without Hepatic Impairment treatment 1 completed NCT01271387
Pharmacokinetics of Tasimelteon in Subjects With Mild or Moderate Hepatic Impairment basic_science 1 completed NCT02004587
Influence of Hepatic Impairment on Pharmacokinetic (PK) and Pharmacodynamic (PD) of Gemigliptin PK and PD After Multiple Oral Doses in Healthy White Volunteers treatment 1 completed NCT01621633
A Study of LCZ696 in Subjects With Mild and Moderate Hepatic Impairment Compared With Normal Healthy Volunteers Not Available 2 completed NCT02256033
Effect of Mild Hepatic Impairment on the Pharmacokinetics of Istradefylline basic_science 1 completed NCT02150733
Pharmacokinetics of Tivantinib in Subjects With Advanced Solid Tumors and Hepatic Impairment treatment 1 completed NCT03627754
A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Glasdegib basic_science 1 completed NCT04190654
Single-dose Study to Investigate the Plasma PK of KW-6356 and Its Major Metabolite other 1 completed NCT05098054
A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function basic_science 1 completed NCT05684653
Study to Evaluate Orelabrutinib Tablets in Subjects With Hepatic Impairment and Healthy Subject other 1 recruiting NCT04016077
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of PF-06651600 in Subjects With Hepatic Impairment and Healthy Volunteers basic_science 1 completed NCT01516047
A Pharmacokinetic Study of Abiraterone Acetate in Patients With Severe Hepatic Impairment Compared to Patients With Normal Hepatic Function No drug interventions treatment 1 completed NCT01949545
Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Advanced Malignancies and Hepatic Impairment other 1 completed NCT04271098
The Investigation of the Causes of Hepatic Dysfunction in the Postoperative Period During Open-heart Surgeries No drug interventions Not Available Not Available completed NCT03706898
Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact of Food Intake and Drug-Drug Interactions With Other Antiviral Drugs treatment 1 completed NCT02296905
Pharmacokinetics and Safety of ABT-493 and/or ABT-530 in Subjects With Normal and Impaired Hepatic Function basic_science 1 completed NCT00812305
Hepatic Impairment Study: Pharmacokinetics in Healthy and Hepatically Impaired Subjects treatment 1 completed NCT02693197
PK Study of T-817 in Subjects With Hepatic Impairment basic_science 1 completed NCT04091061
Effect Of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of PF-06865571 In Subjects With Hepatic Impairment and in Healthy Subjects No drug interventions basic_science 1 completed NCT06352528
A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic Impairment treatment 1 recruiting NCT05409911
A Study to Assess S-217622 in Participants With Mild and Moderate Hepatic Impairment and Healthy Control Participants No drug interventions treatment 1 completed NCT05724693
Study of Bemnifosbuvir in Subjects With Normal and Impaired Hepatic Function treatment 1 completed NCT03824678
Evaluate the Pharmacokinetics of CC-220 in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared With Healthy Subjects treatment 1 completed NCT01790607
An Open-label, Single-dose, Intravenous Administration Study of ONO-2745/CNS 7056 in Subjects With Chronic Hepatic Impairment treatment 1 completed NCT00768209
A Study to Evaluate the Pharmacokinetics of VI-0521 in Subjects With Hepatic Impairment treatment 1 completed NCT01134185
Evaluation of Prucalopride in Subjects With Moderate and Severe Hepatic Impairment treatment 1 completed NCT03189615
Study Investigating the Pharmacokinetic Properties of the Drug Lu AF35700 in Subjects With Liver Impairment and in Healthy Subjects No drug interventions treatment 1 completed NCT01429337
PK and Safety of Midostaurin in Subjects With Impaired Hepatic Function and Subjects With Normal Hepatic Function basic_science 1 completed NCT05599932
Pharmacokinetics and Safety Study of Siremadlin (HDM201) in Participants With Mild, Moderate and Severe Hepatic Impairment treatment 1 completed NCT04332432
A Single-dose, Open-label, Pharmacokinetic Study of Belapectin (GR-MD-02) in Subjects With Normal Hepatic Function and Subjects With Varying Degrees of Hepatic Impairment treatment 1 completed NCT05112952
A Study to Evaluate the Effect of Hepatic Impairment on Lazertinib (JNJ-73841937) basic_science 1 completed NCT05751759
Pharmacokinetics of Mitiperstat in Participants With Hepatic Impairment treatment 1 recruiting NCT06126575
A PK Study Testing Single Oral Dose of Elacestrant in Subjects With Normal or Severely Impaired Hepatic Function No drug interventions other 1 recruiting NCT04166942
KD025 Hepatic Impairment Study With Normal Hepatic Function and Subjects With Varying Degrees of Hepatic Impairment treatment 1 completed NCT03713242
A Study to Evaluate the Pharmacokinetics of ACT-541468 in Subjects With Mild, Moderate, and Severe Hepatic Impairment other 1 completed NCT04208399
A Study to Evaluate the Effect of Hepatic Impairment on JNJ-56136379 treatment 1 completed NCT04631549
An Investigational Study of SHR3680 in Participants With Mild to Moderate Liver Impairment and Healthy Participants basic_science 1 recruiting NCT04225936
A Single-dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of BMS-986263 in Participants With Varying Degrees of Liver Impairment No drug interventions treatment 1 completed NCT05856513
Pharmacokinetics of ZSP1273 in Participants With Hepatic Impairment No drug interventions basic_science 1 completed NCT05112419
A Study to Assess Zibotentan Pharmacokinetics in Participants With Moderate Hepatic and Moderate Renal Impairment treatment 1 completed NCT03376841
Impact of Severe Hepatic Impairment on Pharmacokinetics of Cenicriviroc and Its Metabolites treatment 1 completed NCT03289234
Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Hepatic Impairment other 1 completed NCT02242734
Pharmacokinetics and Metabolism of Hydrocodone Bitartrate Controlled-Release (HC-CR) in Subjects With Hepatic Impairment other 1 completed NCT03440424
Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Mild and Moderate Hepatic Impairment Compared to Healthy Subjects treatment 1 completed NCT05026996
Study to Assess the Pharmacokinetics of Pelacarsen (TQJ230) in Participants With Mild Hepatic Impairment Compared to Matched Healthy Participants other 1 completed NCT04406896
The Effect of Reduced Liver Function on Selatogrel Pharmacokinetics other 1 completed NCT06529796
Evaluation of the Pharmacokinetics and Safety of Inaxaplin in Participants With Mild or Moderate Hepatic Impairment No drug interventions basic_science 1 recruiting NCT04604496
STUDY OF PF-06882961 IN PARTICIPANTS WITH AND WITHOUT VARYING DEGREES OF HEPATIC IMPAIREMENT basic_science 1 completed NCT05891158
A Study About Fazirsiran in People With and Without Liver Problems treatment 1 recruiting NCT05419635
A Study to Learn How the Study Treatment Asundexian Moves Into, Through and Out of the Body, How it Works, How Safe it is, and How it Affects the Body in Participants With Mild or Moderate Reduction of Liver Function Compared to Participants With Normal Liver Function basic_science 1 completed NCT03587363
A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Erdafitinib other 1 terminated NCT01456663
A Study to Evaluate the Pharmacokinetics of AFQ056 in Subjects With Hepatic Impairment Compared to Healthy Subjects other 1 completed NCT01732263
Study of SSP-004184 (SPD602) in Healthy Adults and Subjects With Impaired Liver Function treatment 1 completed NCT03802786
Pharmacokinetics of Imeglimin in Hepatic Impaired Subjects treatment 1 completed NCT01904539
Hepatic Impairment Trial of Obeticholic Acid basic_science 1 completed NCT05467722
Study to Assess the Effect of Hepatic Impairment on the Pharmacokinetics of CTP-543 basic_science 1 completed NCT06094725
A Study to Evaluate the Effects of Hepatic Impairment on the Pharmacokinetics of Relacorilant other 1 completed NCT05490030
Pharmacokinetics of TNO155 in Participants With Mild, Moderate, or Severe Hepatic Impairment Compared to Matched Healthy Participants diagnostic 1 withdrawn NCT03799848
A Single Dose Study of Oral Vadadustat in Subjects With Normal and Impaired Hepatic Function basic_science 1 completed NCT03048448
Pharmacokinetics of Fevipiprant (QAW039) in Patients With Hepatic Impairment Compared to Matched Healthy Subjects other 1 completed NCT02893657
The Role and Dynamics of Liver Dysfunction in Patients Undergoing Cardiac Surgery No drug interventions Not Available Not Available unknown_status NCT01419457
Pharmacokinetics of Favipiravir in Volunteers With Hepatic Impairment basic_science 1 completed NCT01594957
Pharmacokinetics of LCQ908 in Patients With Hepatic Impairment other 1 completed NCT04993157
Pharmacokinetics Study of FIA586 in Participants With Mild and Moderate Hepatic Impairment No drug interventions treatment 1 completed NCT05517226
Pharmacokinetics of Cotadutide in Participants With Hepatic Impairment treatment 1 terminated NCT04859426
A Study to Evaluate the Pharmacokinetics and Safety of DBPR108 in Subjects With Hepatic Impairment No drug interventions treatment 1 completed NCT05814926
GP681 in Volunteers With Hepatic Impairment Compared With Healthy Volunteers No drug interventions treatment 1 completed NCT06052566
A Study of Efinopegdutide in Participants With Hepatic Impairment (MK-6024-014) treatment 1 recruiting NCT04694365
Safety and Pharmacokinetics of Fluzoparib in Healthy Subjects and Those With Impaired Liver Function basic_science 1 completed NCT05101265
Clinical Pharmacokinetic Study of Lurbinectedin in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Impairment treatment 1 recruiting NCT02471274
PK Study of Sotagliflozin in Subjects With Hepatic Impairment treatment 1 completed NCT03277274
A Study to Evaluate the Effect of Hepatic Impairment on the Single Dose Pharmacokinetics (PK) of Intravenous TAK-954 other 1 completed NCT05674474
A Study of Vorasidenib in Participants With Moderate or Mild Hepatic Impairment and Matched Participants With Normal Hepatic Function treatment 1 completed NCT04469920
Hepatic Impairment, Cholestatic Liver Disease, & NASH With Advanced Fibrosis & Normal Hepatic Function other 1 recruiting NCT03816631
A Study of Orally Administered Pimodivir in Adult Participants With Hepatic Impairment other 1 completed NCT04480827
Open-Label Study to Evaluate the Safety, Tolerability, and PK of Aramchol in Subjects With Hepatic Impairment treatment 1 completed NCT00432627
Impact of Hepatic Impairment on the Pharmacokinetics of Deferasirox. treatment 1 completed NCT01600976
A Study to Assess Safety and Pharmacokinetics of Telaprevir in Patients With Hepatic Impairment treatment 1 completed NCT02121860
PK and PD Study of IDN-6556 in Subjects With Hepatic Impairment and Matched Healthy Volunteers treatment 1 completed NCT01529294
Single-dose Iloperidone Pharmacokinetics in Patients With Mild or Moderate Liver Disease, Compared to Healthy Volunteers Not Available 1 completed NCT05078580
Pharmacokinetic (PK) and Safety Study of Iptacopan (LNP023) in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Matched Control Healthy Participants With Normal Hepatic Function. other 1 completed NCT05404529
To Evaluate the Pharmacokinetics (PK) and Safety of Tavapadon in Participants With Mild and Moderate Hepatic Impairment Compared to Participants With Normal Hepatic Function treatment 1 completed NCT01231529
GSK1349572 Hepatic Impairment Study No drug interventions basic_science 1 completed NCT04752540
A Phase I Study to Assess the Pharmacokinetics of Olorofim in Subjects With Hepatic Impairment other 1 completed NCT03114540
Single-Dose PK and Safety Study of GBT440 in Subjects With Hepatic Impairment other 1 completed NCT02452801
Pharmacokinetics and Safety of ALKS 5461 in Healthy Subjects and Subjects With Hepatic Impairment and Normal Hepatic Function No drug interventions treatment 1 completed NCT05731804
Hepatic Impairment and Renal Impairment Study of SIM0417 Combined With Ritonavir No drug interventions treatment 1 not_yet_recruiting NCT06084104
DZD9008 PK Study in Hepatic Impairment Subjects treatment 1 recruiting NCT02367872
Phase I Open-label Study to Evaluate Pharmacokinetics of TAK-272 in Participants With Renal or Hepatic Impairment No drug interventions treatment 1 completed NCT02857868
A Trial to Evaluate the Pharmacokinetics of ABL001 in Healthy and Hepatic Impaired Subjects treatment 1 completed NCT04056468
A Study to Evaluate Pharmacokinetics (PK) and Safety of Oral Mobocertinib in Participants With Moderate or Severe Hepatic Impairment (HI) and Normal Hepatic Function other 1 completed NCT06179368
Throid Dysfunction in Liver Failure and Its Eddects Upon Outcome No drug interventions Not Available Not Available recruiting NCT01027169
A Study to Assess the Effect of Hepatic Impairment on Safinamide Pharmacokinetics basic_science 1 completed NCT01493869
Study to Assess the Pharmacokinetics of Cabozantinib (XL184) in Hepatic Impaired Adult Subjects treatment 1 completed NCT04494269
A Study to Evaluate Pharmacokinetics and Safety of Tegoprazan in Subjects With Hepatic Impairment and Healthy Controls treatment 1 unknown_status NCT05436912
A Study of Effects of Selpercatinib in Hepatically Impaired Participants and Healthy Participants basic_science 1 completed NCT04772612
A Study to Evaluate the Effect of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Sitravatinib treatment 1 completed NCT01443481
Pharmacokinetics (PK) of TKI258 in Cancer Patients With Normal and Impaired Hepatic Function treatment 1 completed NCT04643795
Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses of MGL-3196 in Subjects With Varying Degrees of Hepatic Impairment and Healthy Matched Control Subjects treatment 1 completed NCT03160014
Safety and Pharmacokinetics/Pharmacodynamics of SHR3824 in Patients With Hepatic Impairment treatment 1 unknown_status NCT01222455
A Study of Fostamatinib in Subjects With Impaired Hepatic (Liver) Function basic_science 1 completed NCT01846455
Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects treatment 4 completed NCT03359850
Pharmacokinetic and Safety Study of Niraparib With Normal or Moderate Hepatic Impairment Patients treatment 1 completed NCT04332523
A Study of JNJ-53718678 in Participants With Hepatic Impairment treatment 1 terminated NCT03546608
Tepotinib Hepatic Impairment Trial other 1 completed NCT03606538
MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function basic_science 1 not_yet_recruiting NCT01146938
A Clinical Trial to Compare and Evaluate the Pharmacokinetic Characteristics and the Safety of Fimasartan in Hepatic Impairment Patients and Healthy Volunteers Not Available 1 completed NCT03534843
A Comparison Between Child-Pugh and Albumin-Bilirubin Scores No drug interventions Not Available Not Available completed NCT03290443
A Study to Assess the Pharmacokinetics of Enasidenib (CC-90007) in Subjects With Moderate and Severe Hepatic Impairment. treatment 1 completed NCT05707390
A Study of Mezigdomide in Healthy Participants and Participants With Hepatic Impairment treatment 1 completed NCT04473664
A Study of Quizartinib Pharmacokinetics in Participants With Moderate Hepatic Impairment treatment 1 completed NCT05976321
A Study of TAK-279 in Adults With or Without Liver Damage basic_science 1 completed NCT01565902
Pharmacokinetics of BAF312 in Patients With Hepatic Impairment other 1 completed NCT03902002
A Pharmacokinetic Study of Omaveloxolone in Subjects With Hepatic Impairment and Normal Hepatic Function treatment 1 completed NCT03813979
Pharmacokinetics of Single-dose Dolutegravir in HIV-seronegative Subjects With Severe Hepatic Impairment Compared to Matched Controls. other 4 withdrawn NCT01319279
A Study to Evaluate the Pharmacokinetics of the Hydrocodone Extended-Release Tablet (CEP-33237) in Subjects With Normal Hepatic Function and Subjects With Moderate Hepatic Impairment treatment 1 completed NCT05582187
A Clinical Trial of the Study Medicine (Called Fosmanogepix) in Participants With Varying Degrees of Hepatic Function. basic_science 1 recruiting NCT02095587
Duvelisib in Hepatically Impaired Subjects Compared to Healthy Subjects basic_science 1 completed NCT01431833
A PK and Safety Study in Subjects With Hepatic Impairment Not Available 1 completed NCT04791553
Safety Study of Cenobamate in Subjects With Normal Hepatic Function and Subjects With Severe Hepatic Impairment other 1 completed NCT02683577
Study to Evaluate a Dose of Telotristat Etiprate in Male and Female With Mild, Moderate and Severe Hepatic Insufficiency and Matched Healthy Subjects basic_science 1 completed NCT02115347
Pharmacokinetics, Safety, and Tolerability of Ertugliflozin (MK-8835/PF-04971729) in Participants With Hepatic Impairment and in Healthy Participants (MK-8835-014) treatment 1 completed NCT02621047
Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib treatment 1 completed NCT05515445
Pharmacokinetics of Chiglitazar in Subjects With Hepatic Impairment and Normal Hepatic Function treatment 1 completed NCT02611505
A Study to Assess the Effects of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine treatment 1 completed NCT00736905
TMC278-TiDP6-C130: Pharmacokinetics, Safety and Tolerability of TMC278 in Subjects With Mildly or Moderately Impaired Hepatic Function. Not Available 1 completed NCT00162097
Pharmacokinetics of Efavirenz in HIV-1 Infected Subjects With Hepatic Impairment treatment 1 completed NCT01631097
A Single-Dose Study of Tivozanib in Subjects With Hepatic Impairment and Normal Hepatic Function basic_science 1 completed NCT03983161
A Pharmacokinetics and Tolerability Study of Fedratinib in Subjects With Moderate and Severe Hepatic Impairment treatment 1 completed NCT01727128
Pharmacokinetic Study of BKM120 in Subjects With Hepatic Impairment basic_science 1 completed NCT05481411
A Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Various Degrees of Hepatic Impairment basic_science 1 completed NCT01888393
Study of Lumacaftor in Combination With Ivacaftor in Subjects With Moderate Hepatic Impairment and Healthy Subjects Not Available 1 completed NCT03765671
Elafibranor Pharmacokinetic Parameters in Hepatic Impaired Patients basic_science 1 completed NCT03397888
The Effect o f Hepatic Impairment on the Pharmacokinetics and Pharmacodynamics of Betrixiban, an Oral FXa Antagonist prevention 1 completed NCT04271488
Study to Evaluate the Pharmacokinetics (PK) of E7090 (Herein Referred to as Tasurgratinib) and Its Metabolite in Participants With Mild and Moderate Hepatic Impairment Compared to Healthy Participants No drug interventions treatment 1 recruiting NCT01531309
Pharmacokinetics of AGO178 in Participants With Liver Impairment other 1 completed NCT02286609
A Single Dose Evaluation of the Effects of Moderate Hepatic Impairment on Deflazacort Pharmacokinetics basic_science 1 completed NCT00858156
BG9928 in Subjects With Hepatic Impairment Not Available 1 completed NCT06577415
A Study of RAY1225 in Participants With Impaired Liver Function No drug interventions basic_science 1 recruiting NCT03626415
A Hepatic Impairment Study for PF-04965842. basic_science 1 completed NCT02050815
MEK162 in Healthy Subjects With Normal Hepatic Function and Subjects With Impaired Hepatic Function treatment 1 terminated NCT02474537
INC280 in Healthy Subjects With Impaired Hepatic Function and Subjects With Normal Hepatic Function treatment 1 completed NCT02985632
A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants treatment 1 withdrawn NCT00828932
Pharmacokinetic Properties of Lorcaserin in Subjects With Hepatic Impairment other 1 completed NCT06161259
Pharmacokinetics of Leritrelvir(RAY1216) in Participants With Hepatic Impairment No drug interventions basic_science 1 completed NCT04755075
Surufatinib Hepatic Impairment Study other 1 completed NCT04631575
An Investigational Study of SHR6390 in Participants With Mild to Moderate Liver Impairment and Healthy Participants basic_science 1 unknown_status NCT04482270
A Study to Investigate the Effect of Mild and Moderate Hepatic Impairment on the Safety and Tolerability of Fezolinetant Compared to Participants With Normal Hepatic Function treatment 1 completed NCT02421042
A Pharmacokinetic and Safety Study of E7080 in Subjects With Mild (10 mg), Moderate (10 mg), and Severe Hepatic Impairment (5 mg) and Normal Hepatic Function (10 mg) treatment 1 completed NCT06535399
Study to Assess Drug Levels and Safety of Golcadomide (BMS-986369) in Healthy Participants and Participants With Different Degrees of Hepatic Impairment treatment 1 not_yet_recruiting NCT05484206
Effect of Hepatic Impairment on the Pharmacokinetics and Safety of VIR-2218 and VIR-3434 treatment 1 recruiting NCT00956306
A Pharmacokinetic Study of Udenafil in Adult Subjects With or Without Impaired Hepatic Function supportive_care 1 completed NCT03962049
Safety and Pharmacokinetics Study of Linzagolix in Female Subjects With Normal and Impaired Hepatic Function basic_science 1 completed NCT04193436
A STUDY TO COMPARE THE PHARMACOKINETICS OF PF-06835919 IN PARTICIPANTS WITH AND WITHOUT HEPATIC IMPAIRMENT basic_science 1 completed NCT01984736
EVP-6124 Hepatic Impairment Study treatment 1 completed NCT03282513
A Study of AG-120 (Ivosidenib) in Subjects With Mild or Moderate Hepatic Impairment or Normal Hepatic Function treatment 1 completed NCT03212313
Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Tozadenant basic_science 1 terminated NCT03499041
A Study of LY3314814 in Participants With Liver Impairment basic_science 1 withdrawn NCT02524717
A Study to Evaluate the Pharmacokinetics of JNJ-56021927 in Participants With Mild or Moderate Hepatic Impairment Compared With Participants With Normal Hepatic Function treatment 1 completed NCT06004934
A Study to Evaluate the Pharmacokinetics of Avacopan (CCX168) in Participants With Mild or Moderate Hepatic Impairment treatment 1 completed NCT05391724
Safety and Pharmacokinetics of CMX001 in Impaired Hepatic Function and Healthy Subjects other 1 completed NCT04960124
A Study to Evaluate the Effect of Hepatic Impairment on JNJ-42847922 in Adult Participants treatment 1 completed NCT02571816
A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of ASP2215 basic_science 1 completed NCT04020016
Nalbuphine ER Effects of Liver Disease on Pharmacokinetics and Itch treatment 1 unknown_status NCT06388616
Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Balcinrenone treatment 1 recruiting NCT04145596
Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Patients With Hepatic Impairment diagnostic 1 completed NCT01433458
Pharmacokinetics of RLX030 in Subjects With Mild, Moderate and Severe Hepatic Impairment Compared to Healthy Subjects No drug interventions other 1 completed NCT04241835
A Study to Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function treatment 1 recruiting NCT04208386
A Study to Evaluate the Effect of Hepatic Impairment on JNJ-73763989 No drug interventions treatment 1 completed NCT01126086
Pharmacokinetic, Pharmacodynamic and Tolerability Study of Otamixaban in Patients With Mild and Moderate Hepatic Impairment treatment 1 completed NCT05376839
A Study to Assess Safety of Cedirogant and How Cedirogant Moves Through the Body in Adult Participants With Mild, Moderate and Severe Hepatic Impairment treatment 1 terminated NCT03555539
Study of Danicopan in Participants With Hepatic Impairment basic_science 1 completed NCT04676425
A Study to Investigate the Influence of Hepatic Impairment on MK-8189 Treatment (MK-8189-012) treatment 1 completed NCT00621725
Phase 1 PK Study of Cediranib in Single and Multiple Doses in Hepatically Impaired Patients With Solid Tumours treatment 1 completed NCT05517525
A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Brensocatib in Participants With Normal Hepatic Function and Participants With Hepatic Impairment treatment 1 completed NCT01767948
A Study to Evaluate the Pharmacokinetics of PCI-32765 in Participants With Varying Degrees of Hepatic Impairment treatment 1 completed NCT03968848
Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its Metabolite treatment 1 completed NCT02624557
Pharmacokinetic Study of Alpelisib in Subjects With Hepatic Impairment. basic_science 1 completed NCT03832426
A Pharmacokinetic Study of Narlaprevir as a Single Dose or With Ritonavir Combination in Patients With Hepatic Impairment and Healthy Matched Volunteers treatment 1 completed NCT04208165
PVB Versus TAP in Hepatic Patients Undergoing Laparoscopic Cholecystectomy No drug interventions health_services_research Not Available completed NCT04154774
A Study of Apalutamide in Participants With Severe Hepatic Impairment Compared With Participants With Normal Hepatic Function treatment 1 recruiting NCT04573582
Pharmacokinetics of Enasidenib (CC-90007) in Participants With Mild, Moderate and Severe Hepatic Impairment treatment 1 completed NCT03742882
A Study to Assess the Pharmacokinetics of CC-90001 in Subjects With Mild, Moderate, and Severe Hepatic Impairment Compared With Healthy Subjects treatment 1 completed NCT02244827
Pharmacokinetics of WCK 2349 In Patients With Hepatic Impairment basic_science 1 completed NCT01563562
Single-Dose, Open-Label Pharmacokinetic Study of Bardoxolone Methyl in Subjects With Mild, Moderate, and Severe Hepatic Impairment and Normal Hepatic Function treatment 1 completed NCT04276662
Study of Single-dose DS-3201b in Participants With Hepatic Impairment No drug interventions treatment 1 completed NCT01762462
Open Label Pharmacokinetic Study of SAR302503 in Subjects With Hepatic Impairment treatment 1 completed NCT05009680
A Single and Repeat Dose Trial in Participants With Hepatic Impairment treatment 1 / 2 active_not_recruiting NCT05835180
A Phase I Pharmacokinetic Study of TVB-2640 (Denifanstat) in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function treatment 1 completed NCT04293029
Pharmacokinetics and Safety of SHR0302 in Patients With Hepatic Impairment treatment 1 completed NCT04546789
Effect of Hepatic Impairment on M2951 (BTK Inhibitor) PK treatment 1 completed NCT05386589
A Study to Evaluate Molnupiravir (MK-4482) in Participants With Moderate Hepatic Impairment (MK-4482-016) treatment 1 completed NCT04305392
Pharmacokinetics, Pharmacodynamics and Safety of SHR4640 in Patients With Hepatic Impairment treatment 1 unknown_status NCT05753592
A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Hepatic Impairment Compared With Matched Healthy Participants treatment 1 completed NCT02581592
Pharmacokinetics of TD-4208 in Patients With Moderate Hepatic Impairment basic_science 1 completed NCT05857644
A Study to Compare How the Study Medicine (PF-07923568) is Processed in Participants With Different Levels of Loss of Liver Function to Healthy Participants. basic_science 1 completed NCT05216367
Fruquintinib Hepatic Impairment Study other 1 completed NCT01887301
Assessment of the Single Dose Pharmacokinetics and Tolerability of Sativex in Patients With Impaired Hepatic Function and Healthy Patients treatment 1 completed NCT05790304
Study to Investigate Hepatic Impairment on PK, Safety, Tolerability of Camizestrant in Post-Menopausal Female Subjects other 1 completed NCT00819468
Pharmacokinetics (PK) of 20 mg Teduglutide in Participants With Moderately Impaired Hepatic Function Compared to Healthy Participants other 1 completed NCT05919069
A Phase I Study to Investigate the Effect of Hepatic Impairment on the PK, Safety, and Tolerability of AZD2693 No drug interventions other 1 active_not_recruiting NCT03423446
Study to Evaluate the Pharmacokinetics of Telotristat Ethyl in Subjects With Severe Hepatic Impairment treatment 1 completed NCT04759846
Hepatic Impairment Study of Encorafenib in Combination With Binimetinib in BRAF Melanoma treatment 1 withdrawn NCT05005312
Study to Estimate the Effects of Hepatic Impairment on the Pharmacokinetics (PK) of PF-07321332 basic_science 1 completed NCT00672581
Pharmacokinetics, Safety & Tolerability of ZD4054 (Zibotentan) in Subjects With Normal, Mild, Moderate and Severe Hepatic Impairment treatment 1 completed NCT04252495
The Effect of Hepatic Impairment on Aprocitentan Pharmacokinetics other 1 completed NCT03277755
A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Odalasvir and AL-335 Alone and in Combination With Simeprevir in Participants With Moderately Impaired Hepatic Function other 1 withdrawn NCT02873650
Pharmacokinetics of Dabrafenib in Subjects With Hepatic Impairment basic_science 1 terminated NCT05706623
A Phase 1, Open-Label Evaluation of the Pharmacokinetics and Safety of a Single Dose of Apraglutide in Subjects With Normal and Impaired Hepatic Function treatment 1 completed NCT03722823
A Safety Study of Tucatinib in Healthy and Hepatically-Impaired Subjects treatment 1 completed NCT04552808
To Evaluate the Pharmacokinetics and Safety of Yimitasvir Phosphate Capsules in Subjects With Moderate and Severe Liver Function Impairment and in Healthy Subjects treatment 1 completed NCT05917938
A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function No drug interventions treatment 1 recruiting NCT03686995
Study to Evaluate the PK of ACT-541468 in Subjects With Mild, Moderate, and Severe Hepatic Impairment treatment 1 not_yet_recruiting NCT02231450
Pharmacokinetics Properties of Single Oral Dosing of Lu AE58054 in Subjects With Hepatic Impairment (Mild and Moderate) and in Healthy Subjects treatment 1 completed