Sezary Syndrome

Also known as: Syndrome, Sezary / Sézary disease / Sezary's syndrome / Sezary's disease / Sézary disease, unspecified site / Mycoses fungoides / Mycosis fungoides NOS / Mycosis fungoides

DrugDrug NameDrug Description
DB00997DoxorubicinA medication used to treat various cancers and Kaposi's Sarcoma.
DB00982IsotretinoinA retinoid used to treat severe recalcitrant acne.
DB00552PentostatinAn adenosine deaminase inhibitor used to treat hairy cell leukemia.
DrugDrug NameTargetType
DB00997DoxorubicinDNA topoisomerase 2-alphatarget
DB00997DoxorubicinDNAtarget
DB00997DoxorubicinCytochrome P450 3A4enzyme
DB00997DoxorubicinCytochrome P450 2D6enzyme
DB00997DoxorubicinCytochrome P450 2B6enzyme
DB00997DoxorubicinP-glycoprotein 1transporter
DB00997DoxorubicinCanalicular multispecific organic anion transporter 2transporter
DB00997DoxorubicinMultidrug resistance-associated protein 6transporter
DB00997DoxorubicinMultidrug resistance-associated protein 1transporter
DB00997DoxorubicinMultidrug resistance-associated protein 7transporter
DB00997DoxorubicinATP-binding cassette sub-family G member 2transporter
DB00997DoxorubicinBile salt export pumptransporter
DB00997DoxorubicinSolute carrier family 22 member 16transporter
DB00997DoxorubicinATP-binding cassette sub-family B member 8, mitochondrialtransporter
DB00997DoxorubicinCytochrome P450 1B1enzyme
DB00997DoxorubicinCarbonyl reductase [NADPH] 1enzyme
DB00997DoxorubicinCarbonyl reductase [NADPH] 3enzyme
DB00997DoxorubicinAlcohol dehydrogenase [NADP(+)]enzyme
DB00997DoxorubicinAldo-keto reductase family 1 member C3enzyme
DB00997DoxorubicinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00997DoxorubicinXanthine dehydrogenase/oxidaseenzyme
DB00997DoxorubicinNitric oxide synthase, endothelialenzyme
DB00997DoxorubicinNitric oxide synthase, inducibleenzyme
DB00997DoxorubicinNitric oxide synthase, brainenzyme
DB00997DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialenzyme
DB00997DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrialenzyme
DB00997DoxorubicinNADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrialenzyme
DB00997DoxorubicinNADPH--cytochrome P450 reductaseenzyme
DB00997DoxorubicinRalA-binding protein 1transporter
DB00997DoxorubicinCanalicular multispecific organic anion transporter 1transporter
DB00997DoxorubicinSerum albumincarrier
DB00997DoxorubicinNucleolar and coiled-body phosphoprotein 1target
DB00997DoxorubicinDNA topoisomerase 1target
DB00997DoxorubicinDNA topoisomerase 2-betatarget
DB00982IsotretinoinRetinoic acid receptor alphatarget
DB00982IsotretinoinSerum albumincarrier
DB00982IsotretinoinRetinoic acid receptor gammatarget
DB00982IsotretinoinCytochrome P450 3A4enzyme
DB00552PentostatinAdenosine deaminasetarget
DrugDrug NamePhaseStatusCount
DB11945Avelumab1Active Not Recruiting1
DB06769Bendamustine1Recruiting1
DB00307Bexarotene1Completed1
DB08870Brentuximab vedotin1Withdrawn1
DB01073Fludarabine1Recruiting1
DB00480Lenalidomide1Withdrawn1
DB12498Mogamulizumab1Active Not Recruiting1
DB05527Pralatrexate1Completed1
DB06813Pralatrexate1Completed1
DB12392Resminostat1Completed1
DB00087Alemtuzumab1 / 2Completed1
DB00091Cyclosporine1 / 2Completed1
DB11714Durvalumab1 / 2Recruiting1
DB01073Fludarabine1 / 2Completed1
DB00480Lenalidomide1 / 2Recruiting1
DB16225Magrolimab1 / 2Suspended1
DB12498Mogamulizumab1 / 2Recruiting1
DB12498Mogamulizumab1 / 2Suspended1
DB16307A-dmDT390-bisFv(UCHT1)2Completed1
DB00087Alemtuzumab2Unknown Status1
DB00307Bexarotene2Completed1
DB08870Brentuximab vedotin2Completed1
DB08870Brentuximab vedotin2Recruiting1
DB00091Cyclosporine2Active Not Recruiting1
DB00254Doxycycline2Terminated1
DB00441Gemcitabine2Recruiting1
DB12070Letermovir2Recruiting1
DB12498Mogamulizumab2Recruiting2
DB09035Nivolumab2Recruiting1
DB09037Pembrolizumab2Recruiting2
DB12392Resminostat2Active Not Recruiting1
DB00412Rosiglitazone2Completed1
DB13896Talimogene laherparepvec2Recruiting1
DB02546Vorinostat2Completed1
DB00673Aprepitant4Terminated1
DB00004Denileukin diftitox4Completed2
DB00553MethoxsalenNot AvailableNot Yet Recruiting1