- Accession Number
Carbon-containing phosphonic acid compounds. Included under this heading are compounds that have carbon bound to either OXYGEN atom or the PHOSPHOROUS atom of the (P=O)O2 structure.
Drug Drug Description Pamidronic acid A bisphosphonate used to treat Paget's disease, to treat hypercalcemia of malignancy, and to treat osteolytic bone lesions. Zoledronic acid A bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors. Alendronic acid A bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis. Ibandronate A bisphosphonate used to treat osteoporosis in postmenopausal women. Clodronic acid A bisphosphonate used to treat osteoporosis in postmenopausal women, hypercalcemia of malignancy, and osteolysis. Fosfomycin A broad spectrum antibiotic used to treat uncomplicated urinary tract infections. Risedronic acid A bisphosphonate used to treat osteoporosis and Paget's disease. Etidronic acid A bisphosphonate drug that prevents osteoclastic bone resorption; used for the prevention and treatment of osteoporosis. Tiludronic acid A bisphosphonate used for the treatment of Paget's disease of bone. Phosphonoacetic Acid A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem] Incadronic acid Incadronate has been investigated in the treatment of myeloma,[A14426,A14431] leukemia, and other cancers. It has also been investigated in patients with hypercalcemia of malignancy. Metrifonate Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate. Tenofovir A nucleotide analog indicated in the treatment of HIV infections. Cidofovir An antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS.
- Drugs & Drug Targets