cutaneous candidiasis (DBCOND0020791)

Identifiers

Synonyms

Cutaneous candidiasis caused by candida spp. / Cutaneous candidiasis infection / Candidiasis, Cutaneous / Candidiasis of the Cutaneous / Skin candida / Skin candida NOS / Candida rash / Candidiasis of skin NOS / Candidiasis of skin (disorder) / Moniliasis skin / Moniliasis cutaneous / Cutaneous moniliasis / Monilia of skin NOS / Monilial rash / Thrush of skin NOS

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Amorolfine	A morpholine derivative commonly applied as a lacquer for onychomycosis but is also used for superficial dermatomycosis.	No drug targets
Ciclopirox	A broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients.	Sodium/potassium-transporting ATPase subunit alpha-1target
Clotrimazole	A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.	Intermediate conductance calcium-activated potassium channel protein 4target Cytochrome P450 2D6enzyme Cytochrome P450 2C8enzyme Cytochrome P450 3A4enzyme Cytochrome P450 2B6enzyme ATP-dependent translocase ABCB1transporter Cytochrome P450 2A6enzyme Cytochrome P450 2C9enzyme Cytochrome P450 2E1enzyme Cytochrome P450 3A7enzyme Lanosterol 14-alpha demethylasetarget Nuclear receptor subfamily 1 group I member 2target Hydroxycarboxylic acid receptor 2target Bile salt export pumptransporter Solute carrier organic anion transporter family member 1B1transporter Solute carrier organic anion transporter family member 1B3transporter Ergosteroltarget C-X-C chemokine receptor type 2target
Econazole	A topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.	Aromataseenzyme Cytochrome P450 2E1enzyme Cytochrome P450 3A4enzyme Lanosterol 14-alpha demethylasetarget Nuclear receptor subfamily 1 group I member 2target
Ketoconazole	A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.	Cytochrome P450 3A4enzyme Cytochrome P450 2C9enzyme Cytochrome P450 2C19enzyme Cytochrome P450 3A5enzyme Cytochrome P450 1A2enzyme Cytochrome P450 2C8enzyme Cytochrome P450 1A1enzyme Cytochrome P450 2D6enzyme Bile salt export pumptransporter ATP-dependent translocase ABCB1transporter Cytochrome P450 11B1, mitochondrialenzyme Cytochrome P450 1B1enzyme Cytochrome P450 2A6enzyme Cytochrome P450 2B6enzyme Lanosterol 14-alpha demethylasetarget Androgen receptortarget Steroid 17-alpha-hydroxylase/17,20 lyasetarget Steroid 21-hydroxylasetarget Voltage-gated inwardly rectifying potassium channel KCNH2target Nuclear receptor subfamily 1 group I member 2target Nuclear receptor subfamily 1 group I member 3target UDP-glucuronosyltransferase 1A1enzyme UDP-glucuronosyltransferase 2B7enzyme Solute carrier organic anion transporter family member 1B1transporter Cytochrome P450 4F12enzyme Cytochrome P450 4F2enzyme Albumincarrier Sex hormone-binding globulincarrier Aromataseenzyme UDP-glucuronosyltransferase 1A7enzyme Lanosterol 14-alpha demethylasetarget
Miconazole	An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.	Cytochrome P450 2C9enzyme Cytochrome P450 2D6enzyme Cytochrome P450 3A4enzyme ATP-dependent translocase ABCB1transporter Lanosterol 14-alpha demethylasetarget Nitric oxide synthase 3target Nitric oxide synthase, inducibletarget Cytochrome P450 11B1, mitochondrialenzyme Cytochrome P450 2A6enzyme Cytochrome P450 2B6enzyme Cytochrome P450 2C19enzyme Cytochrome P450 2E1enzyme Nuclear receptor subfamily 1 group I member 2target Lanosterol 14-alpha demethylaseenzyme Aromataseenzyme Calcium-activated potassium channeltarget Voltage-gated Potassium Channelstarget Inward rectifier potassium channeltarget Voltage gated L-type calcium channeltarget Albumincarrier Cytochrome P450 2C8enzyme
Nystatin	A polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species.	Ergosteroltarget Solute carrier organic anion transporter family member 1B1transporter Solute carrier organic anion transporter family member 1B3transporter
Terbinafine	An allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections.	Squalene monooxygenasetarget Cytochrome P450 2D6enzyme Cytochrome P450 2C9enzyme Cytochrome P450 1A2enzyme Cytochrome P450 3A4enzyme Cytochrome P450 2C8enzyme Cytochrome P450 2C19enzyme Prostaglandin G/H synthase 1enzyme Albumincarrier alpha1-acid glycoproteincarrier ABC multidrug transporter MDR2transporter Squalene monooxygenasetarget
Triamcinolone	A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.	Corticosteroid-binding globulincarrier Glucocorticoid receptortarget Cytochrome P450 3A4enzyme Prostaglandin G/H synthase 2enzyme Cholinesteraseenzyme Cytochrome P450 3A5enzyme Cytochrome P450 3A7enzyme Albumincarrier

Clinical Trials

Not Available