Keloids Scars (DBCOND0084610)

Identifiers

Synonyms
Keloidscars / Scar Keloid / Keloid Scar / Keloid Scars / Keloid / Keloids / Hypertrophic scar / Keloid scar (disorder) / Keloid (morphologic abnormality)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Betamethasone
A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
Betamethasone phosphate
A fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions.
Bupivacaine
A local anesthetic used in a wide variety of superficial and invasive procedures.
Dexamethasone
A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
Methylprednisolone
A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
Tetrachlorodecaoxide
Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections, cancer/tumors (unspecified), HIV infection, and inflammatory disorders (unspecified).
Triamcinolone
A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02155439
Treatment of Keloidscars With Intralesional Triamcinolone and 5-fluorouracil Injections-prospective, Randomized, Controlled Trial - Pilot Studytreatment4completed
NCT02886091
Observational Study of Keloids Scars Treated by Shaving and CryosurgeryNo drug interventionsNot AvailableNot Availableunknown_status
NCT04046783
Patch With Onion Extract and Allantoin for C-section ScarNo drug interventionsNot AvailableNot Availablecompleted
NCT04812626
Intralesional Triamcinolone Acetonide and Its Combination With 5-fluorouracil in Keloids and Hypertrophic ScarstreatmentNot Availablecompleted
NCT05072821
Botulinum Toxin Type A Injection to Prevent Keloid Recurrenceprevention4active_not_recruiting
NCT03982862
Botulinum Toxins Intralesional Injection for Scar Paintreatment4unknown_status
NCT02521402
Pilot Study to Evaluate Clinical Outcomes With the Use of Biovance Following Keloid Scar Revision SurgeryNo drug interventionstreatment4unknown_status
NCT01176877
Assessing and Improving Patient Knowledge About Keloid Scars (Keloids)No drug interventionsNot AvailableNot Availablecompleted
NCT04184011
Superficial Radiation Therapy (SRT) for the Treatment of Recurrent Keloid ScarsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03693924
A Retrospective Evaluation of Superficial Radiation Therapy (SRT) and Keloid Scars.No drug interventionsNot AvailableNot Availableunknown_status
NCT01736969
A Substantial Equivalence Study of RD04723 and Predicate DeviceNo drug interventionstreatmentNot Availableunknown_status
NCT04786210
Treatment of Keloids With Fractional Erbium Laser-Assisted 5-Fluorouracil Versus Laser-Assisted Corticosteroidtreatment4completed
NCT01295099
Keloid Scarring: Treatment and Pathophysiologytreatment4withdrawn
NCT04016610
Proof of Concept (POC) Study of the Soliton's Acoustic Scar Reduction (ASR) Treatment for the Treatment of Keloid ScarNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT01720056
Verapamil vs Steroid to Prevent Keloid Recurrenceprevention4terminated
NCT04988022
Dupilumab in the Treatment of Keloidstreatment4active_not_recruiting
NCT06373458
Ritlecitinib in Patients With Keloids or Those Undergoing Keloidectomytreatment2recruiting
NCT02630303
High Fluence Light Emitting Diode-Red Light (LED-RL) in Human SkinNo drug interventionsother1completed
NCT03239964
Surgical Excision and Intralesional Steroid Injection for Prevention of Post Caesarean Keloid Recurrenceprevention4completed
NCT00008502
Genetic Analysis of Familial KeloidsNo drug interventionsNot AvailableNot Availablecompleted
NCT01457079
Keloid Radiation RegistryNo drug interventionsNot AvailableNot Availableunknown_status
NCT00710333
Safety of Juvista When Administered Following Excision of Ear Lobe Keloidstreatment1 / 2completed
NCT01619553
Genetic Analysis of KeloidsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00754247
A Randomized Comparative Study Evaluating the Tolerability and Efficacy of Two Topical Therapies for the Treatment of Keloids and Hypertrophic Scarstreatment4completed
NCT05412745
Class I Medical Device on Post-surgical ScarsNo drug interventionspreventionNot Availablecompleted
NCT03630198
Pain Outcomes Following Intralesional Corticosteroid Injectionstreatment4completed
NCT00476697
UVA1 Light for Scleroderma and Similar ConditionsNo drug interventionstreatmentNot Availableterminated
NCT01423383
Epidemiology Study of KeloidNo drug interventionsNot AvailableNot Availableunknown_status
NCT03228693
Gene Expression and Biomarker Profiling of Keloid SkinNo drug interventionsotherNot Availablecompleted
NCT01425437
Keloid Tissue BankNo drug interventionsNot AvailableNot Availableterminated
NCT01125137
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid ScarNo drug interventionsbasic_scienceNot Availablecompleted
NCT04049552
RAPA-Keloid Study of Keloid Regressiontreatment0completed
NCT03601052
Efficacy, Safety, and Tolerability of Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a History of Keloidstreatment2completed
NCT04553159
Autologous Adipose Derived Stem Cells Transplantation in the Treatment of Keloids.No drug interventionstreatment2completed
NCT01446770
Evaluation of the Initial Safety and Efficacy of Keloid Lesions Treated With MF-4181No drug interventionstreatment2completed
NCT04710719
Post-Surgical Injection With Triamcinolone Versus Triamcinolone/Fluorouracil in Treatment of KeloidstreatmentNot Availablecompleted
NCT05939817
The Effect of Intralesian Injection of Umbilical Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide on Type 1:3 Collagen Ratio and Interleukin-10 Levels in Keloid: A Randomised Controlled Trialtreatment4completed
NCT01994616
Prospective Evaluation of the Use of Intralesional Cryotherapy for Treatment of Keloid and Hypertrophic ScarsNo drug interventionsNot AvailableNot Availablecompleted
NCT03795116
Light Emitting Diode-Red Light (LED-RL) Phototherapy for Skin Scarring PreventionNo drug interventionstreatment2completed
NCT03433222
Phase 1 Study of HF-LED-RL in Fitzpatrick Skin Types I to IIINo drug interventionsother1unknown_status
NCT05461157
Preoperative Silicone Ointment and Wound HealingNo drug interventionspreventionNot Availableenrolling_by_invitation
NCT03312166
Compressive Device to Prevent Keloïd Scars Recurrence [SCARWARS]No drug interventionspreventionNot Availableunknown_status
NCT06431360
Effect of Strontium-90 Brachytherapy Combined With Hyperthermia in the Treatment of KeloidNo drug interventionstreatmentNot Availablerecruiting
NCT04597060
The Safety and Efficacy of Thermo-mechanical System for Fractional Ablation Associated Triamcinolone Acetonide Drug Delivery for the Treatment of Hypertrophic Scars and KeloidsNo drug interventionstreatmentNot Availableunknown_status
NCT05488860
Piezoelectric Drived Microneedling in Treating Refractory Skin DiseasestreatmentNot Availableunknown_status
NCT04915391
Restenosis in Coronary Stents And Cutaneous HEaLingNo drug interventionsNot AvailableNot Availableunknown_status
NCT02922972
Treatment of Keloid Scar by Autologous Platelet Rich Plasma Obtained With RgenKit-BCTNo drug interventionstreatmentNot Availablecompleted
NCT06230146
Efficacy and Safety of Fractional CO2 Laser Combined With Intralesional Insulin, Botulinum Toxin or Triamcinolone Acetonide in the Treatment of Keloid: A Clinical, Dermoscopic and Immunohistochemical Study.treatment1 / 2not_yet_recruiting
NCT04824612
Photobiomodulation and the Intralesional Administration of Corticoid in the Keloid Surgery.treatmentNot Availablecompleted
NCT02005055
High Dose Rate Brachytherapy for Treatment of KeloidsNo drug interventionsNot AvailableNot Availablecompleted
NCT04169438
Pilot Study Investigating a Restorative Wound Care Cream Together With Petrolatum on Surgical ExcisionsNo drug interventionspreventionNot Availablecompleted
NCT02063243
Intralesional Cryotherapy With a Argon Gas Based Device for the Treatment of Keloid and Hypertrophic ScarsNo drug interventionstreatmentNot Availablecompleted
NCT04169490
"A Clinical Study Investigating the Effectiveness of OTC Scar-management Modalities"No drug interventionstreatmentNot Availablecompleted
NCT06138964
Comparing the Effect of siSPARC Microneedle Patch Versus siSPARC+siLR4A Microneedle Patch on Post-surgical ScarsNo drug interventionstreatment2recruiting
NCT04391621
Efficacy of Adipose Derived Stromal Vascular Fraction in the Treatment of Keloidstreatment2unknown_status
NCT00587587
A Pilot Study of Apligraf for the Treatment and Prevention of Recurrence of Excised KeloidsNo drug interventionstreatment1 / 2completed
NCT06034587
Multimodal Ultrasound Imaging Assessment on KeloidNo drug interventionsNot AvailableNot Availablecompleted
NCT03160053
Improving Keloids Using Targeted Ultraviolet-B IrradiationNo drug interventionstreatmentNot Availablecompleted
NCT01408953
Therapeutic Study of Bevacizumab Injection Directly Inside the Keloid Tissuetreatment2terminated
NCT00836147
Exploratory Study of the Efficacy and Safety of Juvista 250ng When Administered Following Excision of Ear Lobe Keloidstreatment1 / 2completed
NCT04582305
Bleomycin Jet Injections in Keloidstreatment4active_not_recruiting
NCT02996097
Fractional Laser Assisted Steroid Therapy vs Intralesional Steroids in the Treatment of KeloidstreatmentNot Availablecompleted
NCT05128383
Study to Assess Efficacy and Safety of Dupilumab in the Treatment of Keloidstreatment2active_not_recruiting
NCT00129428
Ultraviolet B (UVB) Light Therapy in the Treatment of Skin Conditions With Altered Dermal MatrixNo drug interventionsprevention1 / 2completed
NCT00519493
A Randomized Clinical Study Comparing Two Closure Techniques of Excised KeloidsNo drug interventionstreatmentNot Availableterminated
NCT05330078
Examining the Therapeutic Potential of Botulinum Toxin Type A in the Treatment of Keloidstreatment0active_not_recruiting
NCT00565552
Influence of a Silicone Gel (Dermatix®) on Thoracic Scar Formation After Harvesting of Autologous Rib CartilageNo drug interventionstreatmentNot Availableunknown_status
NCT04326959
Implantation of Mesenchymal Stem Cell, Conditioned Medium, or Triamcinolone Acetonide for Keloidtreatment1 / 2unknown_status
NCT04827875
Safety and Efficacy of AIV001 on Scar Formation and Keloid Recurrence Following KeloidectomyNo drug interventionsprevention1completed
NCT05275699
Analyse of Diagnosis Value of Keloid on 68Ga- FAPI-04 PET-CTNo drug interventionsdiagnostic1 / 2completed
NCT04593706
Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids, Hypertrophic Scars)treatmentNot Availableunknown_status
NCT02823236
Efficacy of Intralesional Triamcinolone and 8% Topical Pirfenidone for Treatment of Keloid Scarstreatment3unknown_status
NCT01158196
Safety and Efficacy of Infrared Diode Laser on Improvement of Scar and Prevention of Recurrence of Excised KeloidNo drug interventionsprevention3unknown_status
NCT02923596
Retrospective Study of Keloid DisorderNo drug interventionsNot AvailableNot Availableunknown_status
NCT00469235
Trial of Juvista (Avotermin) Following Removal of Ear Lobe Keloid Scarstreatment1 / 2completed
NCT04722263
Radiotherapy for KeloidsNo drug interventionstreatment0active_not_recruiting
NCT02340325
FS2 Safety and Tolerability Study in Healthy Volunteerstreatment1completed
NCT03460431
A Study Using Fractional Carbon Dioxide and Long Pulsed Neodymium-yttrium Aluminum Garnet Lasers in Treatment of KeloidsNo drug interventionstreatmentNot Availablecompleted
NCT04186273
Clinical Safety and Scar Prevention Study of a Topical Antifibrotic Compound FS2.No drug interventionsprevention2unknown_status
NCT02546076
Comparison of Dual-mode ER:YAG Laser in Patients With Long Keloid/Hypertrophic ScarsNo drug interventionstreatment2withdrawn
NCT04844840
A Study for Safety and Efficacy Evaluation of Various Doses of STP705 in Reducing Keloid Recurrencetreatment2completed
NCT05887804
Comparison of Keloid Volume and Symptoms Reduction Between Intralesional Umbilical-Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide Injection as Keloid Therapy: A Randomised Controlled Trialtreatment4completed
NCT02079168
A Study to Evaluate the Effectiveness and Safety of RXI-109 on the Outcome of Keloid Excision Surgery in Healthy AdultsNo drug interventionstreatment2completed
NCT01789346
Pilot Study of a Novel 532nm KTP Laser for the Treatment of Fresh Surgical ScarsNo drug interventionstreatmentNot Availablecompleted
NCT01423981
Web Based Investigation of Natural History of Keloid Disorder, an Online SurveyNo drug interventionsNot AvailableNot Availablerecruiting
NCT01941914
Calcium Electroporation for the Treatment of Keloidstreatment1completed
NCT03760250
Imiquimod for Preventing Keloid Recurrenceprevention2terminated
NCT05893108
Ethosomal Gel Bearing Losartan 5% for Keloid Treatmenttreatment1 / 2not_yet_recruiting
NCT03887208
Therapy of Scars and Cutis Laxa With Autologous Adipose Derived Mesenchymal Stem CellsNo drug interventionstreatment1 / 2completed
NCT01478243
Study of Psycho-Social Impact of KeloidNo drug interventionsNot AvailableNot Availableterminated
NCT00987545
Efficacy 2 Part Study of Identification of Keloid Biomarkers and Effect of QAX576 on Keloid Recurrencetreatment2terminated
NCT00993005
CICATRIX in the Treatment of Hypertrophic Scars and Keloids ScarsNo drug interventionstreatment3completed
NCT01078428
Effect of Transparent, Self-drying Silicone Gel on the Treatment of Hypertrophic Abdominal ScarsNo drug interventionstreatment4completed
NCT00142441
Effect of Pulse Width on Scar Treatment Using a 595-nm Pulsed Dye LaserNo drug interventionstreatmentNot Availablecompleted
NCT01425216
Sorafenib for Patients With Extensive Keloidstreatment2terminated
NCT01113125
Scars After Central Venous Cathetersprevention3unknown_status
NCT00476801
UVA1 Light for Treatment of Scleroderma and Similar ConditionsNo drug interventionstreatmentNot Availablecompleted