Primary Myelofibrosis

Also known as: Myelofibrosis, Primary / Osteomyelofibrosis / Chronic idiopathic myelofibrosis

DrugDrug NameDrug Description
DB12500FedratinibFedratinib is indicated to treat adults with primary or secondary myelofibrosis that is either intermediate-2 or high risk.
DB08877RuxolitinibA kinase inhibitor used to treat various types of myelofibrosis, polycythemia vera in patients who have not responded to or cannot tolerate hydroxyurea, and to treat graft-versus-host disease in cases that are refractory to steroid treatment.
DrugDrug NamePhaseStatusCount
DB00531Cyclophosphamide0Completed1
DB00099Filgrastim0Completed1
DB01073Fludarabine0Completed1
DB00888Mechlorethamine0Completed1
DB00688Mycophenolate mofetil0Completed1
DB09036Siltuximab0Withdrawn1
DB00864Tacrolimus0Completed1
DB12001Abemaciclib1Recruiting1
DB05812Abiraterone1Recruiting1
DB08916Afatinib1Recruiting1
DB00062Albumin human1Recruiting1
DB01169Arsenic trioxide1Terminated1
DB04456Arsenous acid1Terminated1
DB00126Ascorbic acid1Active Not Recruiting1
DB09495Avobenzone1Recruiting1
DB00928Azacitidine1Completed2
DB05015Belinostat1Completed1
DB00112Bevacizumab1Recruiting1
DB01128Bicalutamide1Recruiting1
DB00188Bortezomib1Recruiting1
DB01008Busulfan1Completed1
DB06772Cabazitaxel1Recruiting1
DB08875Cabozantinib1Recruiting1
DB01101Capecitabine1Recruiting1
DB00958Carboplatin1Recruiting1
DB01413Cefepime1Completed1
DB00482Celecoxib1Recruiting1
DB05239Cobimetinib1Recruiting1
DB12483Copanlisib1Recruiting1
DB00531Cyclophosphamide1Completed1
DB00987Cytarabine1Completed1
DB08912Dabrafenib1Recruiting1
DB11963Dacomitinib1Recruiting1
DB12941Darolutamide1Recruiting1
DB01254Dasatinib1Recruiting1
DB00694Daunorubicin1Recruiting1
DB01262Decitabine1Completed1
DB01262Decitabine1Withdrawn1
DB00997Doxorubicin1Recruiting1
DB11714Durvalumab1Recruiting1
DB11714Durvalumab1Withdrawn1
DB13874Enasidenib1Recruiting1
DB08899Enzalutamide1Recruiting1
DB00530Erlotinib1Recruiting1
DB00773Etoposide1Completed1
DB01590Everolimus1Recruiting1
DB14491Ferrous fumarate1Active Not Recruiting1
DB00099Filgrastim1Completed1
DB01073Fludarabine1Active Not Recruiting1
DB01073Fludarabine1Completed1
DB01073Fludarabine1Withdrawn1
DB00544Fluorouracil1Recruiting1
DB12396Fresolimumab1Terminated1
DB13040Gandotinib1Completed1
DB09054Idelalisib1Recruiting1
DB00619Imatinib1Completed1
DB00619Imatinib1Recruiting1
DB06186Ipilimumab1Recruiting1
DB15763Iron polymaltose1Active Not Recruiting1
DB16541Lactobacillus casei1Active Not Recruiting1
DB09078Lenvatinib1Recruiting1
DB00650Leucovorin1Recruiting1
DB12130Lorlatinib1Recruiting1
DB00678Losartan1Recruiting1
DB00888Mechlorethamine1Active Not Recruiting1
DB00888Mechlorethamine1Withdrawn1
DB00688Mycophenolate mofetil1Completed1
DB00688Mycophenolate mofetil1Terminated1
DB11828Neratinib1Recruiting1
DB09035Nivolumab1Recruiting1
DB09496Octinoxate1Recruiting1
DB09074Olaparib1Recruiting1
DB00526Oxaliplatin1Recruiting1
DB12638PU-H711Terminated1
DB01229Paclitaxel1Recruiting1
DB09073Palbociclib1Recruiting1
DB06603Panobinostat1Recruiting1
DB09037Pembrolizumab1Recruiting1
DB06366Pertuzumab1Recruiting1
DB08901Ponatinib1Recruiting1
DB08896Regorafenib1Recruiting1
DB08877Ruxolitinib1Active Not Recruiting1
DB08877Ruxolitinib1Recruiting1
DB08877Ruxolitinib1Terminated1
DB08877Ruxolitinib1Withdrawn1
DB16322Sabatolimab1Withdrawn1
DB00877Sirolimus1Active Not Recruiting1
DB00877Sirolimus1Completed1
DB00877Sirolimus1Recruiting1
DB00877Sirolimus1Terminated1
DB00877Sirolimus1Withdrawn1
DB09143Sonidegib1Completed1
DB00398Sorafenib1Recruiting1
DB14892Spartalizumab1Withdrawn1
DB01268Sunitinib1Completed1
DB01268Sunitinib1Recruiting1
DB00864Tacrolimus1Active Not Recruiting1
DB00864Tacrolimus1Withdrawn1
DB08911Trametinib1Recruiting1
DB05773Trastuzumab emtansine1Recruiting1
DB00755Tretinoin1Recruiting1
DB08881Vemurafenib1Recruiting1
DB11581Venetoclax1Recruiting1
DB08828Vismodegib1Recruiting1
DB02546Vorinostat1Completed1
DB02546Vorinostat1Recruiting1
DB01008Busulfan1 / 2Completed1
DB00531Cyclophosphamide1 / 2Completed1
DB12500Fedratinib1 / 2Recruiting1
DB01073Fludarabine1 / 2Completed1
DB11763Momelotinib1 / 2Completed2
DB12784NS-0181 / 2Completed1
DB06603Panobinostat1 / 2Unknown Status1
DB08910Pomalidomide1 / 2Recruiting1
DB08877Ruxolitinib1 / 2Completed2
DB08877Ruxolitinib1 / 2Recruiting1
DB09143Sonidegib1 / 2Completed1
DB00945Acetylsalicylic acid2Recruiting1
DB06605Apixaban2Recruiting1
DB00126Ascorbic acid2Active Not Recruiting1
DB00928Azacitidine2Recruiting1
DB00394Beclomethasone dipropionate2Completed1
DB01008Busulfan2Active Not Recruiting1
DB01008Busulfan2Recruiting2
DB01008Busulfan2Terminated1
DB00531Cyclophosphamide2Active Not Recruiting1
DB00531Cyclophosphamide2Recruiting4
DB00531Cyclophosphamide2Terminated1
DB00091Cyclosporine2Completed1
DB01406Danazol2Completed1
DB01262Decitabine2Active Not Recruiting1
DB01262Decitabine2Recruiting1
DB01609Deferasirox2Completed1
DB01609Deferasirox2Terminated1
DB06317Elotuzumab2Recruiting1
DB12500Fedratinib2Recruiting2
DB14491Ferrous fumarate2Active Not Recruiting1
DB00099Filgrastim2Recruiting1
DB01073Fludarabine2Active Not Recruiting1
DB01073Fludarabine2Completed4
DB01073Fludarabine2Recruiting5
DB01073Fludarabine2Terminated1
DB05036Grn163l2Completed1
DB00619Imatinib2Completed1
DB14909Imetelstat2Completed2
DB05258Interferon alfa2Recruiting1
DB15763Iron polymaltose2Active Not Recruiting1
DB12085LCL-1612Active Not Recruiting1
DB16541Lactobacillus casei2Active Not Recruiting1
DB00480Lenalidomide2Completed1
DB12281Luspatercept2Recruiting1
DB00888Mechlorethamine2Recruiting4
DB01042Melphalan2Completed1
DB16620Methopterin2Recruiting2
DB00563Methotrexate2Completed2
DB00563Methotrexate2Recruiting2
DB08893Mirabegron2Completed1
DB11763Momelotinib2Completed2
DB00688Mycophenolate mofetil2Active Not Recruiting1
DB00688Mycophenolate mofetil2Completed3
DB00688Mycophenolate mofetil2Recruiting4
DB01024Mycophenolic acid2Recruiting1
DB12784NS-0182Not Yet Recruiting1
DB09035Nivolumab2Terminated1
DB00904Ondansetron2Completed1
DB14852PRM-1512Completed1
DB11697Pacritinib2Completed1
DB11697Pacritinib2Withdrawn1
DB06603Panobinostat2Completed1
DB05922Patidegib2Completed1
DB12655Patidegib2Completed1
DB09037Pembrolizumab2Completed1
DB00635Prednisone2Completed1
DB00172Proline2Recruiting1
DB15119Ropeginterferon alfa-2b2Recruiting1
DB06164Ruxolitinib2Completed1
DB08877Ruxolitinib2Completed4
DB08877Ruxolitinib2Recruiting5
DB08877Ruxolitinib2Terminated2
DB11942Selinexor2Recruiting1
DB00877Sirolimus2Recruiting1
DB01268Sunitinib2Terminated1
DB00864Tacrolimus2Active Not Recruiting1
DB00864Tacrolimus2Completed3
DB00864Tacrolimus2Recruiting5
DB01041Thalidomide2Completed1
DB04572Thiotepa2Recruiting1
DB04960Tipifarnib2Completed1
DB11940Triapine2Completed1
DB06210Eltrombopag2 / 3Active Not Recruiting1
DB01406Danazol3Active Not Recruiting1
DB01406Danazol3Recruiting1
DB12500Fedratinib3Recruiting2
DB01005Hydroxyurea3Recruiting1
DB01005Hydroxyurea3Unknown Status1
DB05258Interferon alfa3Unknown Status1
DB12281Luspatercept3Recruiting2
DB11763Momelotinib3Active Not Recruiting1
DB11763Momelotinib3Completed1
DB11697Pacritinib3Recruiting1
DB11697Pacritinib3Terminated2
DB14867Parsaclisib3Not Yet Recruiting1
DB14867Parsaclisib3Recruiting3
DB00008Peginterferon alfa-2a3Unknown Status1
DB00022Peginterferon alfa-2b3Unknown Status1
DB08910Pomalidomide3Completed1
DB08877Ruxolitinib3Completed1
DB08877Ruxolitinib3Not Yet Recruiting1
DB08877Ruxolitinib3Recruiting5
DB06603Panobinostat4Recruiting1
DB08877Ruxolitinib4Recruiting1
DB05220AlisertibNot AvailableActive Not Recruiting1
DB09312Antilymphocyte immunoglobulin (horse)Not AvailableCompleted1
DB00098Antithymocyte immunoglobulin (rabbit)Not AvailableCompleted1
DB01008BusulfanNot AvailableCompleted1
DB00531CyclophosphamideNot AvailableCompleted1
DB00091CyclosporineNot AvailableCompleted1
DB01073FludarabineNot AvailableCompleted2
DB00529FoscarnetNot AvailableCompleted1
DB01004GanciclovirNot AvailableCompleted1
DB14509Lithium carbonateNot AvailableCompleted1
DB01042MelphalanNot AvailableCompleted1
DB00563MethotrexateNot AvailableCompleted1
DB00688Mycophenolate mofetilNot AvailableCompleted1
DB00039PaliferminNot AvailableCompleted1
DB00864TacrolimusNot AvailableCompleted1
DB01610ValganciclovirNot AvailableCompleted1