Pancreatic Metastatic Cancer

Also known as: Metastatic Pancreatic Cancer / Metastatic Pancreatic Cancers / Pancreatic Cancer Metastatic / Pancreatic Cancer, Metastatic / Pancreas Cancer, Metastatic / Metastatic Cancer Pancreas / Metastatic Pancreas Cancer / Metastases to pancreas / Malignant neoplasm of pancreas metastatic / Pancreas neoplasm malignant metastatic / Secondary malignant neoplasm of pancreas (disorder) / Pancreatic carcinoma stage IV / Pancreatic carcinoma metastatic

Drug	Drug Name	Drug Description
DB00530	Erlotinib	An EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.
DB00650	Leucovorin	A folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer.

Drug	Drug Name	Target	Type
DB00530	Erlotinib	Epidermal growth factor receptor	target
DB00530	Erlotinib	Cytochrome P450 3A4	enzyme
DB00530	Erlotinib	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
DB00530	Erlotinib	ATP-dependent translocase ABCB1	transporter
DB00530	Erlotinib	Nuclear receptor subfamily 1 group I member 2	target
DB00530	Erlotinib	Cytochrome P450 3A5	enzyme
DB00530	Erlotinib	Cytochrome P450 1A1	enzyme
DB00530	Erlotinib	Cytochrome P450 1A2	enzyme
DB00530	Erlotinib	Cytochrome P450 1B1	enzyme
DB00530	Erlotinib	Cytochrome P450 2D6	enzyme
DB00530	Erlotinib	Cytochrome P450 2C8	enzyme
DB00530	Erlotinib	UDP-glucuronosyltransferase 1A1	enzyme
DB00530	Erlotinib	Albumin	carrier
DB00530	Erlotinib	Alpha-1-acid glycoprotein 1	carrier
DB00530	Erlotinib	Solute carrier organic anion transporter family member 2B1	transporter
DB00530	Erlotinib	Epidermal growth factor receptor	enzyme
DB00650	Leucovorin	Organic anion transporter 3	transporter
DB00650	Leucovorin	Proton-coupled folate transporter	target
DB00650	Leucovorin	Dihydrofolate reductase	target

Drug	Drug Name	Phase	Status	Count
DB00544	Fluorouracil	Not Available	Completed	1
DB00762	Irinotecan	Not Available	Completed	1
DB00650	Leucovorin	Not Available	Completed	1
DB13982	Lutetium Lu-177	0	Recruiting	1
DB15568	Adagrasib	1	Recruiting	1
DB08916	Afatinib	1	Unknown Status	1
DB08885	Aflibercept	1	Completed	1
DB00126	Ascorbic acid	1	Completed	1
DB00126	Ascorbic acid	1	Recruiting	1
DB15676	Balstilimab	1	Not Yet Recruiting	1
DB12411	Bemcentinib	1	Completed	1
DB16651	Botensilimab	1	Not Yet Recruiting	1
DB11666	Buparlisib	1	Completed	1
DB01373	Calcium	1	Terminated	1
DB04690	Camptothecin	1	Terminated	1
DB01101	Capecitabine	1	Completed	1
DB01101	Capecitabine	1	Terminated	1
DB00262	Carmustine	1	Recruiting	1
DB00482	Celecoxib	1	Not Yet Recruiting	1
DB00608	Chloroquine	1	Not Yet Recruiting	1
DB12109	Devimistat	1	Unknown Status	1
DB00997	Doxorubicin	1	Withdrawn	1
DB11714	Durvalumab	1	Completed	1
DB00530	Erlotinib	1	Completed	2
DB00898	Ethanol	1	Recruiting	1
DB00544	Fluorouracil	1	Active Not Recruiting	2
DB00544	Fluorouracil	1	Completed	2
DB00544	Fluorouracil	1	Terminated	1
DB11911	Galunisertib	1	Completed	1
DB00441	Gemcitabine	1	Active Not Recruiting	1
DB00441	Gemcitabine	1	Completed	4
DB00441	Gemcitabine	1	Recruiting	4
DB00441	Gemcitabine	1	Terminated	1
DB00441	Gemcitabine	1	Unknown Status	3
DB00441	Gemcitabine	1	Withdrawn	2
DB17293	Hiltonol	1	Completed	1
DB17293	Hiltonol	1	Withdrawn	1
DB00200	Hydroxocobalamin	1	Recruiting	1
DB06186	Ipilimumab	1	Completed	1
DB00762	Irinotecan	1	Active Not Recruiting	2
DB00762	Irinotecan	1	Terminated	1
DB17988	Ivospemin	1	Completed	1
DB12085	LCL-161	1	Unknown Status	1
DB01259	Lapatinib	1	Terminated	1
DB00650	Leucovorin	1	Completed	1
DB00650	Leucovorin	1	Terminated	1
DB16225	Magrolimab	1	Active Not Recruiting	1
DB04835	Maraviroc	1	Completed	1
DB01042	Melphalan	1	Recruiting	1
DB15225	Mitazalimab	1	Completed	1
DB17561	Nisevokitug	1	Terminated	1
DB09035	Nivolumab	1	Active Not Recruiting	2
DB09035	Nivolumab	1	Completed	1
DB09035	Nivolumab	1	Recruiting	2
DB00526	Oxaliplatin	1	Active Not Recruiting	2
DB00526	Oxaliplatin	1	Completed	2
DB00526	Oxaliplatin	1	Terminated	2
DB15034	PRI-724	1	Completed	1
DB01229	Paclitaxel	1	Active Not Recruiting	1
DB01229	Paclitaxel	1	Completed	2
DB01229	Paclitaxel	1	Recruiting	3
DB01229	Paclitaxel	1	Unknown Status	3
DB01229	Paclitaxel	1	Withdrawn	1
DB13431	Proglumide	1	Withdrawn	1
DB17156	RP-72	1	Recruiting	1
DB15766	Retifanlimab	1	Withdrawn	1
DB11182	Rose bengal	1	Active Not Recruiting	1
DB19201	Tamnorzatinib	1	Recruiting	1
DB15320	Toll-like receptor 9	1	Recruiting	1
DB00072	Trastuzumab	1	Recruiting	1
DB15368	Yttrium Y-90 clivatuzumab tetraxetan	1	Withdrawn	1
DB16412	Adebrelimab	1 / 2	Recruiting	1
DB00062	Albumin human	1 / 2	Completed	1
DB00126	Ascorbic acid	1 / 2	Withdrawn	3
DB12689	Azeliragon	1 / 2	Recruiting	1
DB00112	Bevacizumab	1 / 2	Terminated	1
DB15387	Bintrafusp alfa	1 / 2	Terminated	1
DB18723	Cambritaxestat	1 / 2	Recruiting	1
DB01101	Capecitabine	1 / 2	Completed	2
DB01101	Capecitabine	1 / 2	Terminated	1
DB00002	Cetuximab	1 / 2	Completed	1
DB00515	Cisplatin	1 / 2	Withdrawn	3
DB11646	Conatumumab	1 / 2	Completed	1
DB01262	Decitabine	1 / 2	Recruiting	1
DB00390	Digoxin	1 / 2	Recruiting	1
DB11714	Durvalumab	1 / 2	Recruiting	1
DB11714	Durvalumab	1 / 2	Terminated	1
DB12342	Ensituximab	1 / 2	Completed	1
DB00530	Erlotinib	1 / 2	Not Yet Recruiting	1
DB00530	Erlotinib	1 / 2	Withdrawn	1
DB01590	Everolimus	1 / 2	Completed	1
DB16168	Fluorocyclopentenylcytosine	1 / 2	Completed	1
DB00544	Fluorouracil	1 / 2	Not Yet Recruiting	1
DB00544	Fluorouracil	1 / 2	Unknown Status	1
DB00544	Fluorouracil	1 / 2	Withdrawn	1
DB12205	Ganitumab	1 / 2	Completed	1
DB00441	Gemcitabine	1 / 2	Completed	5
DB00441	Gemcitabine	1 / 2	Not Yet Recruiting	1
DB00441	Gemcitabine	1 / 2	Recruiting	2
DB00441	Gemcitabine	1 / 2	Terminated	1
DB00441	Gemcitabine	1 / 2	Withdrawn	5
DB17585	Immunocytokine NHS-IL12	1 / 2	Terminated	1
DB12827	Indoximod	1 / 2	Completed	1
DB00762	Irinotecan	1 / 2	Not Yet Recruiting	1
DB00762	Irinotecan	1 / 2	Withdrawn	1
DB00650	Leucovorin	1 / 2	Not Yet Recruiting	1
DB00650	Leucovorin	1 / 2	Unknown Status	1
DB00650	Leucovorin	1 / 2	Withdrawn	1
DB06075	Linsitinib	1 / 2	Withdrawn	1
DB00331	Metformin	1 / 2	Recruiting	1
DB16251	Necuparanib	1 / 2	Terminated	1
DB11707	Olaptesed Pegol	1 / 2	Completed	1
DB06043	Olaratumab	1 / 2	Completed	1
DB00526	Oxaliplatin	1 / 2	Completed	1
DB00526	Oxaliplatin	1 / 2	Not Yet Recruiting	1
DB00526	Oxaliplatin	1 / 2	Unknown Status	1
DB01229	Paclitaxel	1 / 2	Completed	5
DB01229	Paclitaxel	1 / 2	Not Yet Recruiting	1
DB01229	Paclitaxel	1 / 2	Recruiting	1
DB01229	Paclitaxel	1 / 2	Terminated	1
DB01229	Paclitaxel	1 / 2	Withdrawn	4
DB00085	Pancrelipase	1 / 2	Recruiting	1
DB11065	Pancrelipase amylase	1 / 2	Recruiting	1
DB13147	Pancrelipase lipase	1 / 2	Recruiting	1
DB11066	Pancrelipase protease	1 / 2	Recruiting	1
DB05922	Patidegib	1 / 2	Completed	1
DB12655	Patidegib	1 / 2	Completed	1
DB09037	Pembrolizumab	1 / 2	Completed	1
DB16425	Rintatolimod	1 / 2	Recruiting	1
DB00641	Simvastatin	1 / 2	Recruiting	1
DB15569	Sotorasib	1 / 2	Withdrawn	1
DB15310	Vactosertib	1 / 2	Recruiting	1
DB07232	Veliparib	1 / 2	Unknown Status	1
DB17569	2-O, 3-O desulfated heparin	2	Terminated	1
DB11703	Acalabrutinib	2	Completed	1
DB11703	Acalabrutinib	2	Terminated	1
DB00640	Adenosine	2	Recruiting	1
DB00062	Albumin human	2	Recruiting	2
DB00062	Albumin human	2	Unknown Status	1
DB00041	Aldesleukin	2	Recruiting	1
DB06013	Aldoxorubicin	2	Withdrawn	1
DB06645	Anamorelin	2	Recruiting	1
DB11885	Anlotinib	2	Recruiting	1
DB12378	Apricoxib	2	Completed	1
DB05971	Archexin	2	Completed	1
DB00126	Ascorbic acid	2	Recruiting	1
DB11595	Atezolizumab	2	Recruiting	1
DB11945	Avelumab	2	Withdrawn	1
DB05136	Bavituximab	2	Completed	1
DB00112	Bevacizumab	2	Completed	1
DB00112	Bevacizumab	2	Terminated	1
DB00112	Bevacizumab	2	Withdrawn	1
DB17465	CD-16 NK-92 cells	2	Withdrawn	1
DB15414	CM-4307	2	Not Yet Recruiting	1
DB17323	CRS-207	2	Completed	1
DB08875	Cabozantinib	2	Recruiting	1
DB14776	Camrelizumab	2	Recruiting	1
DB01101	Capecitabine	2	Completed	2
DB01101	Capecitabine	2	Recruiting	1
DB01101	Capecitabine	2	Unknown Status	1
DB01101	Capecitabine	2	Withdrawn	1
DB14707	Cemiplimab	2	Completed	1
DB14917	Ceralasertib	2	Recruiting	1
DB00002	Cetuximab	2	Completed	1
DB00002	Cetuximab	2	Terminated	1
DB00515	Cisplatin	2	Completed	1
DB00515	Cisplatin	2	Recruiting	1
DB11246	Copper gluconate	2	Terminated	1
DB00531	Cyclophosphamide	2	Completed	1
DB00531	Cyclophosphamide	2	Recruiting	1
DB00531	Cyclophosphamide	2	Withdrawn	1
DB01254	Dasatinib	2	Completed	1
DB00004	Denileukin diftitox	2	Terminated	1
DB01234	Dexamethasone	2	Completed	1
DB00822	Disulfiram	2	Terminated	1
DB01248	Docetaxel	2	Completed	1
DB16481	Dociparstat sodium	2	Terminated	1
DB15627	Dostarlimab	2	Completed	1
DB11714	Durvalumab	2	Recruiting	2
DB11714	Durvalumab	2	Withdrawn	1
DB17464	ETBX-011	2	Withdrawn	1
DB17528	ETBX-021	2	Withdrawn	1
DB17529	ETBX-051	2	Withdrawn	1
DB17530	ETBX-061	2	Withdrawn	1
DB01225	Enoxaparin	2	Completed	1
DB11841	Entinostat	2	Completed	1
DB00530	Erlotinib	2	Completed	4
DB00530	Erlotinib	2	Unknown Status	1
DB01073	Fludarabine	2	Recruiting	1
DB00544	Fluorouracil	2	Active Not Recruiting	1
DB00544	Fluorouracil	2	Completed	9
DB00544	Fluorouracil	2	Not Yet Recruiting	1
DB00544	Fluorouracil	2	Withdrawn	1
DB05698	GI-4000	2	Withdrawn	1
DB17532	GI-6207	2	Withdrawn	1
DB17533	GI-6301	2	Withdrawn	1
DB00441	Gemcitabine	2	Active Not Recruiting	7
DB00441	Gemcitabine	2	Completed	17
DB00441	Gemcitabine	2	Not Yet Recruiting	1
DB00441	Gemcitabine	2	Recruiting	4
DB00441	Gemcitabine	2	Terminated	5
DB00441	Gemcitabine	2	Unknown Status	6
DB00441	Gemcitabine	2	Withdrawn	2
DB01067	Glipizide	2	Recruiting	1
DB06186	Ipilimumab	2	Active Not Recruiting	1
DB06186	Ipilimumab	2	Completed	1
DB00762	Irinotecan	2	Active Not Recruiting	4
DB00762	Irinotecan	2	Completed	6
DB00762	Irinotecan	2	Not Yet Recruiting	1
DB00762	Irinotecan	2	Recruiting	2
DB00762	Irinotecan	2	Unknown Status	1
DB04845	Ixabepilone	2	Completed	1
DB17346	LSTA1	2	Active Not Recruiting	1
DB00480	Lenalidomide	2	Completed	1
DB00650	Leucovorin	2	Active Not Recruiting	2
DB00650	Leucovorin	2	Completed	8
DB00650	Leucovorin	2	Not Yet Recruiting	1
DB00650	Leucovorin	2	Recruiting	2
DB00650	Leucovorin	2	Withdrawn	1
DB11596	Levoleucovorin	2	Completed	1
DB14123	Menthol	2	Completed	1
DB00331	Metformin	2	Completed	1
DB11137	Molybdenum	2	Completed	1
DB11793	Niraparib	2	Completed	1
DB11793	Niraparib	2	Recruiting	1
DB12005	Nirogacestat	2	Terminated	1
DB09035	Nivolumab	2	Active Not Recruiting	1
DB09035	Nivolumab	2	Completed	3
DB09035	Nivolumab	2	Terminated	1
DB18740	Nogapendekin alfa	2	Withdrawn	1
DB09074	Olaparib	2	Recruiting	4
DB11707	Olaptesed Pegol	2	Not Yet Recruiting	1
DB00526	Oxaliplatin	2	Active Not Recruiting	3
DB00526	Oxaliplatin	2	Completed	5
DB00526	Oxaliplatin	2	Not Yet Recruiting	1
DB00526	Oxaliplatin	2	Withdrawn	2
DB01229	Paclitaxel	2	Active Not Recruiting	7
DB01229	Paclitaxel	2	Completed	6
DB01229	Paclitaxel	2	Not Yet Recruiting	1
DB01229	Paclitaxel	2	Recruiting	5
DB01229	Paclitaxel	2	Terminated	4
DB01229	Paclitaxel	2	Unknown Status	3
DB01229	Paclitaxel	2	Withdrawn	1
DB00910	Paricalcitol	2	Completed	1
DB14912	Pegvorhyaluronidase alfa	2	Completed	1
DB09037	Pembrolizumab	2	Active Not Recruiting	1
DB09037	Pembrolizumab	2	Completed	2
DB09037	Pembrolizumab	2	Not Yet Recruiting	1
DB09037	Pembrolizumab	2	Recruiting	2
DB12257	Platinum	2	Completed	1
DB06809	Plerixafor	2	Completed	1
DB13431	Proglumide	2	Recruiting	1
DB15766	Retifanlimab	2	Recruiting	1
DB15073	Ribose	2	Recruiting	1
DB14765	Rivoceranib	2	Unknown Status	2
DB18462	Saltikva	2	Active Not Recruiting	1
DB11857	Seribantumab	2	Completed	1
DB16330	Simurosertib	2	Completed	1
DB00820	Tadalafil	2	Completed	1
DB15043	Toripalimab	2	Recruiting	1
DB00512	Vancomycin	2	Completed	1
DB08828	Vismodegib	2	Completed	1
DB15118	Zolbetuximab	2	Active Not Recruiting	1
DB14776	Camrelizumab	2 / 3	Recruiting	1
DB00441	Gemcitabine	2 / 3	Recruiting	3
DB17988	Ivospemin	2 / 3	Recruiting	1
DB01229	Paclitaxel	2 / 3	Recruiting	3
DB15106	Surufatinib	2 / 3	Recruiting	1
DB00062	Albumin human	3	Completed	1
DB00062	Albumin human	3	Recruiting	1
DB14776	Camrelizumab	3	Recruiting	1
DB06168	Canakinumab	3	Active Not Recruiting	1
DB00758	Clopidogrel	3	Terminated	1
DB12109	Devimistat	3	Completed	1
DB00470	Dronabinol	3	Active Not Recruiting	1
DB00544	Fluorouracil	3	Completed	1
DB15637	Fluzoparib	3	Terminated	1
DB12205	Ganitumab	3	Completed	1
DB00441	Gemcitabine	3	Active Not Recruiting	1
DB00441	Gemcitabine	3	Completed	3
DB00441	Gemcitabine	3	Recruiting	1
DB00441	Gemcitabine	3	Terminated	1
DB00441	Gemcitabine	3	Unknown Status	1
DB00762	Irinotecan	3	Active Not Recruiting	1
DB00762	Irinotecan	3	Completed	2
DB00650	Leucovorin	3	Completed	2
DB00650	Leucovorin	3	Unknown Status	1
DB00526	Oxaliplatin	3	Completed	1
DB00526	Oxaliplatin	3	Unknown Status	1
DB01229	Paclitaxel	3	Active Not Recruiting	1
DB01229	Paclitaxel	3	Completed	2
DB01229	Paclitaxel	3	Recruiting	1
DB14952	Pamrevlumab	3	Active Not Recruiting	1
DB14892	Spartalizumab	3	Active Not Recruiting	1
DB15368	Yttrium Y-90 clivatuzumab tetraxetan	3	Terminated	1
DB00441	Gemcitabine	Not Available	Completed	3
DB01229	Paclitaxel	Not Available	Completed	2