Recurrent Epithelial Ovarian Cancer (DBCOND0052406)

Identifiers

Synonyms
Ovarian Epithelial Cancer Recurrent / Recurrent, Epithelial Ovarian Cancer / Recurrent Ovarian Epithelial Cancer / Recurrent Epithelial Cancer of Ovary / Recurrent ovarian cancer (disorder) / Ovarian cancer recurrent

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Niraparib
A poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy.
Olaparib
A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.
Rucaparib
A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat recurrent ovarian and prostate cancers in previously treated adults.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01735071
Bevacizumab and Trabectedin +/- Carboplatin in Advanced Ovarian Cancertreatment2completed
NCT01376752
Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) in Relapse Ovarian Cancer TreatmentNo drug interventionstreatment3active_not_recruiting
NCT01899599
PankoMab-GEX™ Versus Placebo as Maintenance Therapy in Advanced Ovarian Cancertreatment2completed
NCT02026921
A Phase II Study of Docetaxel and Carboplatin in Late Relapse of Ovarian Cancertreatment2completed
NCT02735928
Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) Applied to Platinum-Resistant Recurrence of Ovarian TumorNo drug interventionstreatmentNot Availablecompleted
NCT02394015
Retrospective Study to Analyze the Efficacy and Safety of Trabectedin and Pegylated Liposomal Doxorubicin (PLD ) in the Treatment of Patients With Platinum-sensitive Recurrent Ovarian Cancer (ROC), According to SmPCNot AvailableNot Availablecompleted
NCT02014337
Mifepristone and Eribulin in Patients With Metastatic Triple Negative Breast Cancer or Other Specified Solid Tumorstreatment1completed
NCT01611766
Surgery or Chemotherapy in Recurrent Ovarian Cancer (SOC 1 Trial)?No drug interventionstreatment3unknown_status
NCT02260544
Bioequivalence Study of Doxorubicin Hydrochloride Liposome Injectiontreatment1completed
NCT01715168
A Crossover Bioequivalence Study of Intravenously Administered ATI0918 and DOXIL/CAELYX in Patients With Ovarian Cancertreatment1unknown_status
NCT01588964
IPHC in Patients With Platinum-sensitive Recurrent Ovarian CancerNo drug interventionstreatment2completed
NCT01472783
Veliparib Monotherapy for Relapsed Ovarian Cancer With BRCA Mutationtreatment1 / 2completed
NCT01334047
Trial of Vaccine Therapy in Recurrent Platinum Sensitive Ovarian Cancer PatientsNo drug interventionstreatment1 / 2terminated
NCT01815528
Feasibility and Clinical Activity of Initial Intraperitoneal Catumaxomab Followed by Chemotherapy in Patients With Recurrent Ovarian Cancertreatment2completed
NCT02785250
Study of DPX-Survivac Therapy in Patients With Recurrent Ovarian Cancertreatment1 / 2active_not_recruiting
NCT05335993
A Clinical Study Evaluating a Combination of Oregovomab and Niraparib in Adult Women With Platinum Sensitive Recurrent Ovarian Cancer.treatment2active_not_recruiting
NCT05444270
Salvage Systemic Therapy With or Without Stereotactic Ablative Radiotherapy for Recurrent Ovarian CancerNo drug interventionstreatmentNot Availablerecruiting
NCT01853644
Tivozanib in Recurrent, Platinum-Resistant Ovarian, Fallopian Tube or Primary Peritoneal Cancertreatment2completed
NCT05700669
Study To Assess Safety And Efficacy Of AsiDNA In Combination With Olaparib In Participants With Recurrent Solid Tumorstreatment1 / 2recruiting
NCT01982487
Vaccine Therapy and IDO1 Inhibitor INCB024360 in Treating Patients With Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Who Are in Remissiontreatment1 / 2withdrawn
NCT00036751
Imatinib Mesylate in Treating Patients With Stage III or Stage IV Ovarian Epithelial or Primary Peritoneal Cancertreatment2completed
NCT01233505
Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumorstreatment1terminated
NCT00334893
Eribulin Mesylate in Treating Patients With Recurrent Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancertreatment2completed
NCT01558778
Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell TransplantNo drug interventionssupportive_careNot Availablewithdrawn
NCT00004032
Tumor Vaccine and Interferon Gamma in Treating Patients With Refractory Epithelial Ovarian Cancertreatment1completed
NCT00006942
Bryostatin 1 and Cisplatin in Treating Patients With Advanced Recurrent or Residual Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancertreatment2completed
NCT00348699
AFP464 in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By SurgeryNo drug interventionstreatment1completed
NCT01673217
Decitabine, Vaccine Therapy, and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancertreatment1completed
NCT00390234
Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcomatreatment2completed
NCT00993616
Belinostat and Carboplatin in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer That Did Not Respond to Carboplatin or Cisplatintreatment2completed
NCT00093496
Gemcitabine Hydrochloride and Tanespimycin in Treating Patients With Recurrent Advanced Ovarian Epithelial or Peritoneal Cavity Cancertreatment2completed
NCT02275039
p53MVA Vaccine and Gemcitabine Hydrochloride in Treating Patients With Recurrent Ovarian Epithelial Cancertreatment1completed
NCT00357448
Denileukin Diftitox Used in Treating Patients With Advanced Refractory Ovarian Cancer, Primary Peritoneal Carcinoma, or Epithelial Fallopian Tube Cancertreatment1completed
NCT01962948
Paclitaxel and Ganetespib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancertreatment1 / 2terminated
NCT01846520
Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung CancersNo drug interventionssupportive_careNot Availablecompleted
NCT00538031
Cyclophosphamide With or Without Celecoxib in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancertreatment2completed
NCT00081276
3-AP and Cisplatin in Treating Patients With Recurrent or Persistent Platinum-Resistant Ovarian Epithelial or Primary Peritoneal Cancertreatment2completed
NCT01652794
Carboplatin, Gemcitabine Hydrochloride, and Stereotactic Body Radiation Therapy in Gynecological Cancertreatment1completed
NCT00089362
Alvespimycin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumorstreatment1completed
NCT00016289
Interleukin-12 in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancertreatment2completed
NCT01764789
Stress Reduction in Improving Quality of Life in Patients With Recurrent Gynecologic or Breast CancerNo drug interventionssupportive_careNot Availablecompleted
NCT01159067
Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overloadsupportive_care2terminated
NCT00132067
Vorinostat in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cavity Cancertreatment2completed
NCT00060372
Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancertreatment1completed
NCT00023712
Bortezomib in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer or Primary Peritoneal Cancertreatment2completed
NCT00031681
7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)treatment1completed
NCT00408681
Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplantsupportive_careNot Availablecompleted
NCT00091195
Depsipeptide (Romidepsin) in Treating Patients With Recurrent Ovarian Epithelial or Peritoneal Cavity Cancertreatment2terminated
NCT01536054
Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancertreatment1completed
NCT00030498
Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunctiontreatment1completed
NCT00335998
Phase I Study of Intravenous Triapine (IND # 68338) in Combination With Pelvic Radiation Therapy With or Without Weekly Intravenous Cisplatin Chemotherapy for Locally Advanced Cervical, Vaginal, or Pelvic Gynecologic Malignanciestreatment1completed
NCT01747798
Auranofin in Treating Patients With Recurrent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancertreatment0completed
NCT01200797
SJG-136 in Treating Patients With Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer That Did Not Respond to Previous Treatment With Cisplatin or Carboplatintreatment2terminated
NCT00275028
AZD2171 in Treating Patients With Recurrent Ovarian, Peritoneal, or Fallopian Tube Cancertreatment2completed
NCT00429793
Temsirolimus in Treating Patients With Refractory or Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancertreatment2completed
NCT01927393
Palliative Care in Improving Quality of Life and Symptoms in Patients With Stage III-IV Pancreatic or Ovarian CancerNo drug interventionssupportive_careNot Availablewithdrawn
NCT02050009
Metformin Hydrochloride, Carboplatin, and Paclitaxel in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancertreatment1withdrawn
NCT02122185
Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancertreatment2active_not_recruiting
NCT00388037
Sunitinib Malate in Treating Patients With Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancertreatment2completed
NCT01079832
Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological MalignanciesNo drug interventionstreatment2completed
NCT00022659
Bevacizumab in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer or Primary Peritoneal Cancertreatment2completed
NCT00126542
Bevacizumab and Erlotinib in Treating Patients With Recurrent or Metastatic Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancertreatment2completed
NCT00041041
Imatinib Mesylate in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Primary Peritoneal Cancertreatment2completed
NCT01155258
Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumorstreatment1completed
NCT00228358
Cyclophosphamide or Denileukin Diftitox Followed By Expanding a Patient's Own T Cells in the Laboratory in Treating Patients With HER-2/Neu Overexpressing Metastatic Breast Cancer, Ovarian Cancer, or Non-Small Cell Lung Cancer Previously Treated With HER-2/Neu Vaccinetreatment1completed
NCT00028535
Interleukin-12, Paclitaxel, and Trastuzumab in Treating Patients With Solid Tumorstreatment1completed
NCT00083122
Cisplatin and Flavopiridol in Treating Patients With Advanced Ovarian Epithelial Cancer or Primary Peritoneal Cancertreatment2completed
NCT00053365
Irofulven in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cancertreatment2completed
NCT00004074
Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neutreatment1completed
NCT00113373
Lapatinib in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Peritoneal Cancertreatment2completed
NCT00466960
Sargramostim and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer That Did Not Respond to Previous Chemotherapytreatment2completed
NCT00026091
Fenretinide in Treating Patients With Recurrent or Metastatic Ovarian Epithelial or Primary Peritoneal Cancertreatment2completed
NCT00087191
EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung CancerdiagnosticNot Availableterminated
NCT00039091
Monoclonal Antibody Therapy in Treating Patients With Ovarian Epithelial Cancer, Melanoma, Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Non-Small Cell Lung Cancertreatment1terminated
NCT00041080
Tamoxifen Compared With Thalidomide in Treating Women With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancertreatment3completed
NCT00182767
Ixabepilone and Liposomal Doxorubicin in Advanced Ovarian Cancertreatment1 / 2completed
NCT00436501
VEGF Trap and Docetaxel in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancertreatment1 / 2completed
NCT00795769
Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplantsupportive_care2completed
NCT01126346
Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC)No drug interventionssupportive_careNot Availablecompleted
NCT01494012
Phase I Stereotactic Body Radiation for Metastatic or Recurrent Platinum-Resistant Ovarian Cancertreatment1terminated
NCT00313612
Oxaliplatin and Topotecan in Advance Ovarian Cancertreatment2terminated
NCT00096395
Sorafenib Tosylate and Gemcitabine Hydrochloride in Treating Patients With Recurrent Epithelial Ovarian Cancertreatment2completed
NCT00063895
Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer, Ovarian Cancer, or Squamous Cell Carcinoma of the Head and Necktreatment1 / 2completed
NCT01281514
A Study of Carboplatin, PLD and Everolimus in Certain Gynecologic Cancertreatment1completed
NCT00025155
Ixabepilone in Treating Patients With Ovarian Epithelial or Primary Peritoneal Cancer That Has Not Responded to Previous Chemotherapytreatment2completed
NCT00408655
Temsirolimus, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Tumorstreatment1completed
NCT00278343
Cediranib Maleate in Treating Patients With Persistent, Recurrent, or Refractory Advanced Ovarian Epithelial, Peritoneal Cavity, or Fallopian Tube Cancertreatment2completed
NCT01249443
Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infectiontreatment1terminated
NCT02046421
Carboplatin, Gemcitabine Hydrochloride, and Mifepristone in Treating Patients With Advanced Breast Cancer or Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancertreatment1completed
NCT03312114
Anti-PD-L1 and SAbR for Ovarian Cancertreatment2terminated