Ascites (DBCOND0004927)

Identifiers

Synonyms
Other ascites / Ascites (disorder) / Fluid in peritoneal cavity (finding)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Amiloride
A pyrizine compound used to treat hypertension and congestive heart failure.
Etacrynic acid
A diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease.
Furosemide
A loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
Hydrochlorothiazide
A thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
Spironolactone
An aldosterone receptor antagonist used to treat edema, hypertension, heart failure, and aldosteronism.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05900050
Efficacy, Safety and Tolerability of VS-01 in Adult Patients With Acute-on-Chronic Liver Failure and Ascites (UNVEIL-IT)®No drug interventionstreatment2recruiting
NCT06594562
Free Fluid Detection with Telementored EFASTNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT02400164
A (M)Ulti-center, Prospective, (O)Pen Label, Uncontrolled Feasibility (S)Tudy to Assess the Safety and Effectiveness of an Automatic Low Flow (A)Scites (Alfa) Pump (I)n Patients With (C)Irrhosis and Refractory or Recurrent AscitesNo drug interventionstreatmentNot Availablecompleted
NCT05867602
High Dose Albumin in Refractory Ascitestreatment2recruiting
NCT04232384
Comparison of "Roll-over' Technique With Standard Abdominal Paracentesis in Suspected Peritoneal CarcinomatosisNo drug interventionsdiagnosticNot Availableterminated
NCT00501384
Satavaptan Dose-Ranging Study in the Prevention of Ascitestreatment2completed
NCT01403987
Improving Performance of Paracentesis in Medical Residency TrainingNo drug interventionsNot AvailableNot Availablecompleted
NCT02417753
AZD9150, a STAT3 Antisense Oligonucleotide, in People With Malignant Ascitestreatment2terminated
NCT02821377
Metabolic Effects of Furosemide +HSS in Refractory Ascitestreatment2completed
NCT04767945
Cirrhosis Registry of Hospitalized PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT01073345
Portal Venous Hemodynamic Changes After HepatectomyNo drug interventionsNot AvailableNot Availableunknown_status
NCT03263598
Validation of Diagnostic Usefulness of the Random Urine Na/K Ratio for Replacement of 24hr Urine Na Excretion in Cirrhotic Patients With AscitesNo drug interventionsNot AvailableNot Availablecompleted
NCT01701297
VSL#3 and Spontaneous Bacterial Peritonitistreatment2terminated
NCT04701697
Phase Ib of Recombinant Human Albumin Injectiontreatment1completed
NCT00796861
Trial of Sunitinib for Refractory Malignant Ascitestreatment2terminated
NCT02742428
Preoperative Ascites Drainage Versus Standard Care for Patients With Advanced Ovarian CancerNo drug interventionssupportive_careNot Availablesuspended
NCT01716611
Tolvaptan for Hyponatremia in Cirrhotic Patients With Ascitestreatment4unknown_status
NCT04315571
Comparing Ascites Relief In Two Standard Treatments: Large Volume Paracentesis Vs. Early Tips Using Viatorr Controlled Expansion StentsNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00358878
Cirrhotic Ascites Treatment With Satavaptan in Patients With Ascites Due to Cirrhosis of the Liver (CATS)treatment3completed
NCT05025878
13C-Glucose Tracing of Tumour and T Cells in the Ascites of Ovarian Cancer Patients.No drug interventionsNot AvailableNot Availablerecruiting
NCT03327688
Point-of-care Ultrasound in FinlandNo drug interventionsdiagnosticNot Availablecompleted
NCT06436807
PMCF Study of the CE-marked Drainova® ArgentiC CatheterNo drug interventionsNot AvailableNot Availablerecruiting
NCT01331785
Mechanism and the Effect of Midodrine on Portal Pressures in Patients With CirrhosistreatmentNot Availablewithdrawn
NCT00603200
Effect of Large Volume Paracentesis on Fatigue in CirrhosisNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03827200
A Study Evaluating the Utility of Ambrisentan in Lowering Portal Pressure in Patients With Liver Cirrhosistreatment2terminated
NCT05309200
A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injurytreatment2completed
NCT02891642
Liquid Biopsy With Immunomagnetic Beads Capture Technique for Malignant Cell Detection in Body FluidNo drug interventionsNot AvailableNot Availableunknown_status
NCT06553742
High Definition Profiling of Ovarian Cancer AscitesNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05278013
Utility of 2- Octyl Cyanoacrylate (2-OCA)No drug interventionshealth_services_researchNot Availableenrolling_by_invitation
NCT01150916
B-type Natriuretic Peptide in the Diagnosis of Heart Failure Related AscitesNo drug interventionsdiagnosticNot Availablecompleted
NCT00239096
Prevention of Decompensation in Liver Cirrhosisprevention4unknown_status
NCT02120196
Comparative Study of Rifaximin Versus Norfloxacin in the Secondary Prophylaxis of Spontaneous Bacterial Peritonitisprevention3unknown_status
NCT02649335
To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascitestreatment3completed
NCT01349335
Dose Exploring and Setting Study for Tolvaptan to Treat Hepatic Cirrhosis With Ascitestreatment2completed
NCT00741663
Spironolactone Versus Spironolactone Plus Furosemide (SVSSF)treatment4completed
NCT00501722
Satavaptan Dose-Ranging Study in Hyponatraemic Patients With Cirrhotic Ascitestreatment2completed
NCT01349348
Phase III Study of Tolvaptan Tablet to Treat Cirrhosis Ascitestreatment3completed
NCT01578226
Procalcitonin in Cirrhotic Patients at High Risk for SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT00501566
Satavaptan Dose-Ranging Study in Normonatraemic Patients With Cirrhotic Ascitestreatment2completed
NCT00548366
Sodium Restriction in the Management of Cirrhotic AscitesNo drug interventionstreatment4terminated
NCT04279327
Cell Block Immunohistochemistry in Effusion CytologyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01288794
Human Albumin for the Treatment of Ascites in Patients With Hepatic Cirrhosistreatment4completed
NCT05220891
Comparison of Crystalloid and Colloid I.V Fluid Therapy in Prevention of Paracentesis Induced Circulatory Dysfunction (PICD) and Renal Dysfunction in Patients With Decompensated Liver Cirrhosis in Egypt: a Randomized Piolet StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01359462
Multiple-dose Pharmacokinetics Study of Tolvaptan Tablets in Chinese Patients With Hepatocirrhosistreatment1completed
NCT00327444
Study of the Effect of Intravenous AVE0005 (VEGF Trap) in Advanced Ovarian Cancer Patients With Recurrent Symptomatic Malignant Ascitestreatment2 / 3completed
NCT01769040
Intestinal Decontamination With Rifaximin. The Inflammatory and Circulatory State in Patients With Cirrhosisbasic_science4completed
NCT03493204
Tackling 30-day Readmissions in Patients With Cirrhosis: The SALTYFOOD TrialNo drug interventionstreatmentNot Availablecompleted
NCT01292304
Tolvaptan for Ascites in Cirrhotic Patientstreatment4completed
NCT02787772
Abdominal Hernia in Cirrhotic Patients: Surgery or Conservative Treatment?No drug interventionssupportive_careNot Availablecompleted
NCT00591968
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican CommunityNo drug interventionshealth_services_researchNot Availablecompleted
NCT01188746
Impact of Palliative Catheter Placement on the Quality of Life of Patients With Refractory AscitesNo drug interventionssupportive_careNot Availablecompleted
NCT01455246
Daptomycin + Meropenem Versus Ceftazidime in the Treatment of Nosocomial Spontaneous Bacterial Peritonitistreatment2 / 3terminated
NCT02022150
Body Composition Analysis in Cirrhotic Undergoing ParacentesisNo drug interventionsNot AvailableNot Availableunknown_status
NCT05700708
Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Refractory AscitesNo drug interventionsNot AvailableNot Availablerecruiting
NCT04641364
Safety and Tolerance Study of Recombinant Human Albumin Injection in Healthy Subjects.treatment1completed
NCT03341221
Diagnosis of Ascites in Infants and ChildrenNo drug interventionsNot AvailableNot Availableunknown_status
NCT05013502
Empagliflozin in Diuretic Refractory Ascitestreatment1completed
NCT01091233
The Influence of Paracentesis on Intra-abdominal Pressure and Kidney Function in Critically Ill Patients With Liver Cirrhosis and Ascites: an Observational StudyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT04533854
Investigating Signal Change in Malignant and Non-malignant Pleural Effusions and asCitic Fluid Using fTiR AnalysisNo drug interventionsNot AvailableNot Availablecompleted
NCT02638051
Local mEHT + TCM Versus Intraperitoneal Chemoinfusion in Treatment of Malignant Ascites: Phase II RCTNo drug interventionstreatment2completed
NCT04245553
Does Point of Care Ultrasound Change Needle Insertion Location During Routine Bedside Paracentesis?No drug interventionssupportive_careNot Availablecompleted
NCT00825877
Long-term Follow-up of HALT-C Sustained Virological RespondersNo drug interventionsNot AvailableNot Availablecompleted
NCT00115947
Renal and Cardiovascular Effects of Terlipressin in Patients With Cirrhosis and AscitesNot Available2 / 3completed
NCT03210298
International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)No drug interventionsNot AvailableNot Availableunknown_status
NCT05569798
The INSIGHT Feasibility Study Ultrasound in the Intensive Care Unit: A Randomised Controlled Feasibility TrialNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT01801228
Eplerenone Versus Spironolactone as Treatment of Ascites Due to Liver Cirrhosis; a Study of Efficacy and Side Effectstreatment2withdrawn
NCT03506893
Medical-economic Evaluation of the Care of Refractory Ascites by Implantation of Alfapump® Device in Cirrhotic PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT01777971
The Effect of a Large-volume Paracentesis on Fatigue, Sleep, and Quality of Life in CirrhosisNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01030185
Safety and Performance of the Automated Fluid Shunt in Patients With Ascites and Diuretic ResistanceNo drug interventionstreatment2 / 3completed
NCT03267615
VICIS - Vienna Cirrhosis StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00359437
Satavaptan in the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Livertreatment3terminated
NCT00760032
Lipopolysaccharide Binding Protein and Development of Infectious Events in Cirrhotic Patientsdiagnostic4withdrawn
NCT04675775
The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy.No drug interventionstreatmentNot Availablecompleted
NCT04112199
A Study for Evaluation of BIV201 to Reduce Ascites and Complications in Patients With Cirrhosis and Refractory Ascitestreatment2terminated
NCT02811406
The Role of Intravenous Albumin Replacement During Abdominal Paracentesis in Patients With Malignancy Related AscitespreventionNot Availableunknown_status
NCT00005906
Treatment With Octreotide in Patients With Lymphangioleiomyomatosistreatment2completed
NCT02895919
Bedside Inoculation of Ascitic Fluid in Diagnostic ParacentesisNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00490217
Spontaneous Bacterial Peritonitis: Incidence, Risk Factors and OutcomeNo drug interventionsNot AvailableNot Availablecompleted
NCT04640116
TIPS Combined With Microwave Ablation in HCC Patients With Refractory AscitesNo drug interventionstreatmentNot Availableunknown_status
NCT01059396
Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortalprevention4completed
NCT02608658
Evaluation of Serum-Derived Bovine Immunoglobulin Protein Isolate in Subjects With Decompensated Cirrhosis With AscitesNo drug interventionssupportive_careNot Availablecompleted
NCT01236339
Early TIPS for Ascites StudyNo drug interventionstreatmentNot Availableterminated
NCT00570622
Effect of Pioglitazone on Portal and Systemic Hemodynamics in Patients With Advanced Cirrhosistreatment4completed
NCT03205748
Evaluation of Different Etiologies of Obscure AscitesNo drug interventionsNot AvailableNot Availableunknown_status
NCT02975726
Peritoneal Dialysis Catheters for the Treatment of Refractory AscitestreatmentNot Availablecompleted
NCT03973866
Alfapump® System in the Treatment of Refractory or Recurrent Ascites (POSEIDON Study)No drug interventionstreatmentNot Availableactive_not_recruiting
NCT05511766
Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosisprevention2 / 3recruiting
NCT00006166
North American Study for the Treatment of Refractory Ascites (NASTRA)No drug interventionstreatment3completed
NCT03069131
Two Strategies of Primary Prophylaxis of Spontaneous Bacterial Peritonitis in Severe Cirrhotic Patients With Ascitestreatment3completed
NCT00907673
The Automated Fluid Shunt (AFS)in Chronic Congestive Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT00511394
Acute Hemodynamics of Albumin Versus Normal Saline in CirrhosisdiagnosticNot Availablesuspended
NCT04550091
Role Of Multi-detector Computed Tomography In Differentiation Between Different Types Of AscitesNo drug interventionsNot AvailableNot Availableunknown_status
NCT05734729
Clinical Validation of Programmable Drain Fluid Regulator to Reduce Morbidity, Care Requirements, and Improve OutcomesNo drug interventionstreatmentNot Availablerecruiting
NCT02755701
The Effect of Branched-chain Amino Acid on the Improvement of Serum Albumin Level in Cirrhotic Patients With Ascitestreatment4unknown_status
NCT04650295
Non-Pharmaceutical Intervention for Cirrhotic Cramps Reduction: The NICCles TrialNo drug interventionstreatmentNot Availablecompleted
NCT00968695
Effects of Long Term Albumin 20% Administration in Patients With Cirrhosis and Ascites.treatment4completed
NCT00366795
Satavaptan for the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Livertreatment3terminated
NCT00108355
Vasoconstrictors as Alternatives to Albumin After Large-Volume Paracentesis (LVP) in Cirrhosistreatment4completed
NCT01421550
Conservative Treatment Versus Elective Repair of Umbilical Hernia in Patients With Ascites and Liver CirrhosisNo drug interventionstreatment3unknown_status