Parkinsonian Syndromes (DBCOND0024062)

Identifiers

Synonyms
Parkinsonian Syndrome / Parkinsonian Disorders / Parkinsonism, unspecified / Parkinsonism / Parkinsonism (disorder) / Hypokinetic-rigid syndrome

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Citicoline
An endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects.
Clozapine
An atypical or second-generation antipsychotic drug used in treatment-resistant schizophrenia and to decrease suicide risk in schizophrenic patients.
Diphenhydramine
A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
Fluorodopa (18F)
Fluorodopa F 18 is indicated for use with positron emission tomography (PET) to visualize dopaminergic nerve terminals in the striatum for the evaluation of adult patients with suspected Parkinsonian syndromes...
Ioflupane I-123
A radiopharmaceutical used in single photon emission computed tomography (SPECT) brain imaging to help diagnose patients with suspected Parkinsonian syndromes.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00273351
Imaging and Genetic Biomarkers of Parkinson Disease (PD) Onset and Progression in High-risk FamiliesNo drug interventionsdiagnostic2completed
NCT00129675
Study of Individuals With Parkinson's Symptoms But in Whom There is Diagnostic UncertaintyNo drug interventionsdiagnostic2completed
NCT00117819
A Study of Brain Imaging With Nuclear Medicine Technology in Individuals With and at Risk for Parkinson's DiseaseNo drug interventionsdiagnostic2completed
NCT04925622
Complex Eye Movements in Parkinson's Disease and Related Movement DisordersNo drug interventionsNot AvailableNot Availablecompleted
NCT00096720
Study of the Effects of Dopaminergic Medications on Dopamine Transporter Imaging in Parkinson's DiseaseNo drug interventionsdiagnostic2completed
NCT00096876
A Study of the Sense of Smell in Relatives of Parkinson's Disease PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00117195
A Study of Neurophysiologic Changes in Individuals With Parkinson's DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00354003
The Study of the Impact of Disclosing Imaging Study Information to Trial ParticipantsNo drug interventionsNot AvailableNot Availablecompleted
NCT05110547
Multicenter Study of Blood Biomarkers of Mitochondrial and Peroxisomal Metabolism to Differentiate Idiopathic Parkinson's Disease From Related ConditionsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00368199
Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian SyndromesNo drug interventionsNot AvailableNot Availablecompleted
NCT04974034
Movement Disorders Analysis Using a Deep Learning ApproachNo drug interventionsNot AvailableNot Availablecompleted
NCT00132626
Study of Brain Imaging With Nuclear Technology in Individuals With Parkinsonian SyndromeNo drug interventionsdiagnostic2completed
NCT04193527
A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of Parkinsonian Syndrome (PS) in Chinese PatientsNo drug interventionsdiagnostic3completed
NCT00129181
Study of the Effects of Dopaminergic Medications on Dopamine Transporter Density in Subjects With Parkinson's DiseaseNo drug interventionsdiagnosticNot Availablecompleted
NCT00315250
Development of Imaging, Clinical and Biochemical Bio-Markers for Parkinson's DiseaseNo drug interventionsdiagnostic2completed
NCT00724906
Two Separate But Identical Studies Evaluating the Safety and Efficacy of ALTROPANE® in the Use of SPECT Imaging for Upper Extremity Tremordiagnostic3unknown_status
NCT06193278
Individual Neuromodulation for PDSNo drug interventionstreatmentNot Availablerecruiting
NCT02114242
Biomarkers in Parkinsonian SyndromesNo drug interventionsNot AvailableNot Availablerecruiting
NCT06161636
Contribution of the Kinematic Theory in the Early Differential Diagnosis of the Parkinson's DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT00382967
A Study to Assess Changes in Clinical Management After DaTSCAN Imaging of Subjects With Clinically Uncertain Parkinsonism or an Illness With Similar SymptomsNo drug interventionstreatment4completed
NCT02696603
Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower)No drug interventionsbasic_scienceNot Availableunknown_status
NCT04871464
Role and Mechanism of Probiotics in Improving Motor Symptoms in Mild to Moderate Parkinson's DiseaseNo drug interventionstreatment4recruiting
NCT03156647
Alpha-synuclein Level in Saliva to Differentiate Between Idiopathic Parkinson Disease and Iatrogenic Parkinsonian SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT04847609
GentleCath Air (Urinary Self-catheterization) - Pain in Female Patients With Neurological Vesico-sphincter DisordersNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01491932
Open-label, Long-term Safety Extension Study of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesiastreatment2completed
NCT01380899
Usefulness of α-synuclein as a Marker for Early Diagnosis of Parkinson's Disease in Skin Biopsy.No drug interventionsNot AvailableNot Availablecompleted
NCT00686699
Study of Preladenant for the Treatment of Antipsychotic Induced Movement Disorders in Participants With Schizophrenia (Study P04628)treatment2terminated
NCT04704349
Latest Imaging SPECT System Evaluation Phase 1No drug interventionsotherNot Availablecompleted
NCT02994719
Gait Analysis in Neurological DiseaseNot AvailableNot Availablerecruiting
NCT04985539
The Personalized Parkinson Project de Novo CohortNo drug interventionsNot AvailableNot Availableunknown_status
NCT04237948
tDCS Plus Physical Therapy for Progressive Supranuclear PalsyNo drug interventionstreatmentNot Availablecompleted
NCT01491529
Evaluation of the Efficacy and Safety of Modified Release AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesiastreatment2completed
NCT01385592
Evaluation of the Efficacy and Safety of AFQ056 in Parkinson's Patients With L-dopa Induced DyskinesiasNo drug interventionstreatment2completed
NCT05452655
Intensive Multidisciplinary Rehabilitation and Biomarkers in Parkinson's DiseaseNo drug interventionstreatmentNot Availableunknown_status
NCT01853150
Repetitive Transcranial Magnetic Stimulation for Freezing of GaitNo drug interventionstreatmentNot Availablecompleted
NCT02021903
Post-prandial Hypotension and Sleepiness in Parkinson's Disease and Other SynucleinopathiesNo drug interventionsdiagnosticNot Availablecompleted
NCT03649503
The National Registry Study For the Real-world Patients With Parkinsonian Disorders in ChinaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05356845
Oral Health, Orofacial Function and Oral Health Care in Patients With Parkinson's DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT05608915
External vs Internal-triggered Augmented-reality Visual Cues to Treat Freezing of GaitNo drug interventionstreatmentNot Availablecompleted
NCT06193252
Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-NetherlandsNo drug interventionspreventionNot Availablerecruiting
NCT05906719
Machine Vision Based MDS-UPDRS III Machine RatingNo drug interventionsNot AvailableNot Availablerecruiting
NCT04727658
Linac FRACtionated Radiosurgical THALamotomie in Tremors (FRACTHAL)No drug interventionstreatment2not_yet_recruiting
NCT00355927
Sedation During Microelectrode Recordings Before Deep Brain Stimulation for Movement Disorders.No drug interventionstreatmentNot Availableunknown_status
NCT03065192
Safety and Efficacy Study of VY-AADC01 for Advanced Parkinson's DiseaseNo drug interventionstreatment1completed
NCT03130595
West Sweden Parkinson Objective Measurement Registry StudyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01662414
Effect of Undenatured Cysteine-Rich Whey Protein Isolate (HMS 90®) in Patients With Parkinson's DiseaseNo drug interventionssupportive_care4completed
NCT06283043
Effect of Motor Function, Depression and Sleep Quality on Attention in Parkinson's DiseaseNo drug interventionsNot AvailableNot Availableenrolling_by_invitation