Bronchospasm (DBCOND0013567)
Identifiers
- Synonyms
- Bronchial Spasm / Bronchospasm (rare) / Bronchospasms / Spasm bronchial / Bronchospasm (finding) / Bronchospasm NOS
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Albuterol A beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms.Ambroxol acefyllinate A bronchodilator indicated in the symptomatic treatment of bronchopulmonary disorders associated with bronchospasm.Aminophylline A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.- cGMP-inhibited 3',5'-cyclic phosphodiesterase 3Atarget
- Adenosine receptor A3target
- Adenosine receptor A1target
- Cytochrome P450 1A2enzyme
- Cytochrome P450 2E1enzyme
- Cytochrome P450 3A4enzyme
- Histone deacetylase 2target
Atropine A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs.- Muscarinic acetylcholine receptor M2target
- Muscarinic acetylcholine receptor M1target
- Muscarinic acetylcholine receptor M4target
- Muscarinic acetylcholine receptor M5target
- Muscarinic acetylcholine receptor M3target
- Glycine receptor subunit alpha-1target
- Neuronal acetylcholine receptor subunit alpha-4target
- Neuronal acetylcholine receptor subunit beta-2target
- Bile salt export pumptransporter
- Alpha-1-acid glycoprotein 1carrier
Bambuterol A long acting beta2-adrenoceptor agonist for the management of lung diseases associated with bronchospasm.- Beta-2 adrenergic receptortarget
- Cholinesteraseenzyme
- Cholinesterasetarget
Bamifylline A methylxanthine derivative indicated in the treatment of bronchial asthma and other conditions with bronchospasm.- Cytochrome P450 1A2enzyme
Caroverine A calcium channel blocker indicated in the treatment of smooth muscle spasms, alcohol and drug withdrawal, and tinnitus.- Cytochrome P450 3A4enzyme
Dyphylline A theophylline derivative used to treat asthma, bronchospasm, and COPD.Epinephrine A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.- Alpha-1A adrenergic receptortarget
- Beta-1 adrenergic receptortarget
- Beta-2 adrenergic receptortarget
- Solute carrier family 22 member 2transporter
- Solute carrier family 22 member 1transporter
- Cytochrome P450 2C9enzyme
- Cytochrome P450 3A4enzyme
- Alpha-1B adrenergic receptortarget
- Alpha-1D adrenergic receptortarget
- Alpha-2A adrenergic receptortarget
- Alpha-2B adrenergic receptortarget
- Tumor necrosis factortarget
- Catechol O-methyltransferaseenzyme
- Monoamine oxidaseenzyme
Etafedrine A beta-2 adrenoceptor agonist used to treat a cough associated with inflamed mucosa.Guaifenesin An expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses.- NMDA receptortarget
Ipratropium An anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD).- Muscarinic acetylcholine receptor M1target
- Muscarinic acetylcholine receptor M2target
- Muscarinic acetylcholine receptor M3target
- Organic cation/carnitine transporter 2transporter
- Solute carrier family 22 member 4transporter
- Albumincarrier
- alpha1-acid glycoproteincarrier
Isoprenaline A catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block.- Beta-1 adrenergic receptortarget
- Beta-2 adrenergic receptortarget
- Beta-3 adrenergic receptortarget
- Cytochrome P450 1A1enzyme
- Superoxide dismutase [Cu-Zn]target
- Cytochrome P450 1B1enzyme
- Albumincarrier
- Catechol O-methyltransferaseenzyme
- Cholinesteraseenzyme
- Interleukin-12 subunit betatarget
Levosalbutamol A beta-2 adrenergic receptor agonist used to treat COPD and asthma.Orciprenaline A beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD.Procaterol A beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD).Terbutaline A beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.- Beta-2 adrenergic receptortarget
- Cholinesteraseenzyme
- Beta-3 adrenergic receptortarget
- Beta-1 adrenergic receptortarget
- Sulfotransferaseenzyme
- UDP-glucuronosyltransferases (UGTs)enzyme
- Organic cation/carnitine transporter 2transporter
- Solute carrier family 22 member 2transporter
Theophylline A xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.- cGMP-inhibited 3',5'-cyclic phosphodiesterase 3Atarget
- 3',5'-cyclic-AMP phosphodiesterase 4Btarget
- Adenosine receptor A2btarget
- 3',5'-cyclic-AMP phosphodiesterase 4Atarget
- cGMP-specific 3',5'-cyclic phosphodiesterasetarget
- Adenosine receptor A1target
- Adenosine receptor A2atarget
- Cytochrome P450 1A2enzyme
- Adenosine deaminaseenzyme
- Cytochrome P450 2E1enzyme
- Cytochrome P450 3A4enzyme
- Solute carrier family 22 member 7transporter
- Cytochrome P450 1A1enzyme
- Cytochrome P450 1B1enzyme
- Cytochrome P450 2D6enzyme
- Histone deacetylase 2target
- Copine-1target
- Minor histocompatibility antigen H13target
- BOS complex subunit NOMO1target
- Poly [ADP-ribose] polymerase 1target
- Protein RIC-3target
- Tubulin monoglycylase TTLL3target
- 5'-nucleotidasetarget
Tulobuterol An inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT01265342 Efficacy of Nebulised Beclometasone in Viral Wheezing Prophylaxis prevention 4 completed NCT02939625 NIV Application in the Treatment of Asthmatic Children No drug interventions treatment Not Available completed NCT03064659 Driving Pressure And EFL in Adult Cardiac Surgery No drug interventions Not Available Not Available completed NCT03000413 Ketamine Efficacy for Acute Severe Bronchospasm in ICU: MACANUDO Trial treatment 2 / 3 completed NCT02419196 Perioperative Change of Regional Ventilation During Spontaneous Breathing No drug interventions Not Available Not Available completed NCT01189396 Escalating and Cumulative-Dose Study of Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety of A006 treatment 2 completed NCT00400660 A First Time In Human Study To Assess The Compound GSK615915 No drug interventions treatment 1 completed NCT05360810 Wei Nasal Jet Tube vs Gastro Laryngeal Tube in Endoscopic Retrograde Cholangiopancreatography No drug interventions screening Not Available completed NCT00806455 Exercise-Induced Bronchospasm in Cystic Fibrosis No drug interventions Not Available Not Available completed NCT00118690 A Study Measuring Asthma Control In Pediatric And Adolescent Subjects Whose Asthma Is Worsened By Activity Or Exercise treatment 4 completed NCT01188577 Epinephrine Inhalation Aerosol USP, a HFA-MDI Study for Assessment of Pharmacokinetics treatment 1 / 2 completed NCT02090205 Mechanical Ventilation During Cardiac Surgery No drug interventions prevention Not Available unknown_status NCT04427605 Efficacy and Safety of Continuous Infusion of Ketamine in Pediatric Intensive Care Unit (KISS Study) No drug interventions Not Available Not Available completed NCT05025709 Bronchospasm During Anesthetic Induction: Study of Clinical Characteristics and Treatments Administered According to Etiology No drug interventions Not Available Not Available completed NCT01174732 Dose-Ranging Study of A006 DPI, in Adult Asthma Patients treatment 2 completed NCT04373499 Virtual Teach-to-Goal Education vs. Brief Education for Children No drug interventions health_services_research Not Available completed NCT05555134 INHALATION CHAMBER MANAGEMENT IN PEDIATRICS: EFFICACY OF AN EDUCATIONAL INTERVENTION IN PATIENTS DIAGNOSED WITH BRONCHOSPASM AND THEIR FAMILY CAREGIVERS. No drug interventions prevention 1 recruiting NCT00118716 A Study Measuring Asthma Control In Pediatric And Adolescent Subjects Whose Asthma Is Worsened By Activity Or Exercise treatment 4 completed NCT03962725 Avoiding Neuromuscular Blockers to Reduce Complications treatment 4 terminated NCT00890162 A Randomized, Double-Blind, Placebo-Controlled Study of Omalizumab for Idiopathic Anaphylaxis treatment 2 completed NCT00634829 Single-Dose Cross-Over Study of the Effects of Albuterol-HFA in Exercise Induced Bronchoconstriction prevention 3 terminated NCT01156701 Prophylactic Efficacy of Relenza Against Influenza A and B Not Available Not Available completed NCT02779595 Change of Regional Ventilation During Spontaneous Breathing After Lung Surgery No drug interventions Not Available Not Available completed NCT05783050 Wei Nasal Jet Tube vs Nasal Cannula Oxygen Support in Gastrointestinal Endoscopy Patients No drug interventions prevention Not Available completed NCT01488643 Observational Study on Obese Patients During General Anesthesia No drug interventions Not Available Not Available unknown_status