Weight Loss

Also known as: All grades weight decrease / All grades decreased weight / Weight decreased / Body Weight Decreased / Weight decrease / Decreased weight / Loss of Weight / Decrease in body weight / Lost weight / Wt loss / Losing wt / Weight loss finding (finding) / Weight loss (& abnormal) / Weight decreasing / Weight decreasing (finding) / Weight decreased (finding)

DrugDrug NameDrug Description
DB00470DronabinolA synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
DB00123LysineAn amino acid commonly found as a component of total parenteral nutrition.
DB01083OrlistatA reversible inhibitor of gastrointestinal lipases indicated for weight loss and weight maintenance.
DrugDrug NameTargetType
DB00470DronabinolCannabinoid receptor 1target
DB00470DronabinolCytochrome P450 3A4enzyme
DB00470DronabinolCytochrome P450 2C9enzyme
DB00470DronabinolCannabinoid receptor 2target
DB00470DronabinolP-glycoprotein 1transporter
DB00470DronabinolATP-binding cassette sub-family G member 2transporter
DB00470DronabinolProstaglandin G/H synthase 1enzyme
DB00470DronabinolCytochrome P450 2C19enzyme
DB00470DronabinolCytochrome P450 1A1enzyme
DB00470DronabinolCytochrome P450 1A2enzyme
DB00470DronabinolCytochrome P450 1B1enzyme
DB00470DronabinolCytochrome P450 2A6enzyme
DB00470DronabinolCytochrome P450 2B6enzyme
DB00470DronabinolCytochrome P450 2D6enzyme
DB00470DronabinolCytochrome P450 2J2enzyme
DB00470DronabinolCytochrome P450 3A5enzyme
DB00470DronabinolCytochrome P450 3A7enzyme
DB00470DronabinolMultidrug resistance-associated protein 1transporter
DB00470DronabinolLiver carboxylesterase 1enzyme
DB00470DronabinolUDP-glucuronosyltransferase 1-1enzyme
DB00470DronabinolUDP-glucuronosyltransferase 1-3enzyme
DB00470DronabinolUDP-glucuronosyltransferase 1-9enzyme
DB00470DronabinolUDP-glucuronosyltransferase 1-10enzyme
DB00123LysineHigh affinity cationic amino acid transporter 1target
DB00123LysineCationic amino acid transporter 4target
DB00123LysineCationic amino acid transporter 3target
DB00123LysineLow affinity cationic amino acid transporter 2target
DB00123LysineLysine--tRNA ligasetarget
DB00123LysineMonocarboxylate transporter 10transporter
DB00123LysineSolute carrier family 22 member 4transporter
DB01083OrlistatPancreatic triacylglycerol lipasetarget
DB01083OrlistatFatty acid synthasetarget
DB01083OrlistatGastric triacylglycerol lipasetarget
DB01083OrlistatCytochrome P450 3A4enzyme
DB01083OrlistatCytosolic phospholipase A2enzyme
DB01083OrlistatSerum albumincarrier
DB01083OrlistatFatty acid synthaseenzyme
DrugDrug NamePhaseStatusCount
DB00996Gabapentin0Not Yet Recruiting1
DB00273Topiramate0Not Yet Recruiting1
DB00472Fluoxetine1Completed1
DB14076Interleukin-1 alpha, human recombinant1Completed1
DB00762Irinotecan1Completed1
DB00331Metformin1Completed1
DB00334Olanzapine1Completed1
DB00503Ritonavir1Completed1
DB00345Aminohippuric acid1 / 2Recruiting1
DB01362Iohexol1 / 2Recruiting1
DB00184Nicotine1 / 2Withdrawn1
DB06151Acetylcysteine2Completed1
DB06645Anamorelin2Active Not Recruiting1
DB06292Dapagliflozin2Completed1
DB06292Dapagliflozin2Terminated1
DB00846Flurandrenolide2Terminated1
DB00480Lenalidomide2Active Not Recruiting1
DB00370Mirtazapine2Suspended1
DB08935Obinutuzumab2Active Not Recruiting1
DB00191Phentermine2Completed1
DB00273Topiramate2Completed2
DB00083Botulinum toxin type A2 / 3Recruiting1
DB00486Nabilone2 / 3Completed1
DB00486Nabilone2 / 3Unknown Status1
DB01276Exenatide3Completed1
DB01592Iron3Completed1
DB06655Liraglutide3Completed1
DB06655Liraglutide3Unknown Status1
DB00351Megestrol acetate3Terminated2
DB06155Rimonabant3Completed1
DB06155Rimonabant3Terminated1
DB13928Semaglutide3Not Yet Recruiting1
DB01105Sibutramine3Terminated1
DB09038Empagliflozin4Recruiting1
DB14963Konjac mannan4Completed1
DB06655Liraglutide4Active Not Recruiting1
DB06655Liraglutide4Completed1
DB06655Liraglutide4Recruiting1
DB04871Lorcaserin4Active Not Recruiting1
DB00904Ondansetron4Recruiting1
DB00191Phentermine4Completed1
DB01220Rifaximin4Not Yet Recruiting1
DB00884Risedronic acid4Completed1
DB13928Semaglutide4Recruiting1
DB04871LorcaserinNot AvailableCompleted1
DB00331MetforminNot AvailableRecruiting1
DB09046MetreleptinNot AvailableTerminated1
DB00370MirtazapineNot AvailableCompleted1
DB00104OctreotideNot AvailableCompleted2
DB01083OrlistatNot AvailableWithdrawn1