Nosocomial Pneumonia

Also known as: Hospital-acquired bacteral pneumonia / Hospital-acquired Pneumonia (HAP) / Pneumonia Hospital Acquired / Hospital Acquired Pneumonia (HAP) / Nosocomial Pneumonia (NP) / Hospital-acquired bacterial pneumonia / Hospital Acquired Pneumonia / Hospital Acquired Bacterial Pneumonia / Pneumonia, Hospital-Acquired / Hospital-Acquired Pneumonia / Nosocomial pneumonia (disorder) / Lung inflammation / Pneumonia, unspecified organism / Pneumonia and influenza &/or pneumonia / Pneumonia / Pneumonia (disorder) / Pneumonia (disorder) [Ambiguous] / Pneumonia NOS / Pneumonia NOS (disorder) / Pulmonitis / Pneumonia, Bacterial / Bacterial pneumonia (disorder) / Pneumonia bacterial / Bacterial pneumonia NOS / Bacterial pneumonia NOS (disorder) / Bacterial pneumonia, unspecified / Pneumonia bacterial NOS / Pneumonia due to bacteria NOS (disorder) / Pneumonia due to gram-positive bacteria

DrugDrug NameDrug Description
DB00479AmikacinAn aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria.
DB14879CefiderocolA cephalosporin antibiotic used in complicated urinary tract infections.
DB00438CeftazidimeAn injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others.
DB04918CeftobiproleA cephalosporin antibiotic used to treat both community and hospital-acquired pneumonia caused by susceptible bacteria.
DB09050CeftolozaneA cephalosporin antibiotic used to treat complicated intra-abdominal infections in combination with metronidazole, complicated urinary tract infections, and hospital-acquired pneumonia.
DB00537CiprofloxacinA second generation fluoroquinolone used to treat various susceptible bacterial infections.
DB00319PiperacillinA penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam­ susceptible, β-lactamase generating strains of several bacteria.
DB09324SulbactamAn beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections.
DB01606TazobactamA beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy.
DB06149TeicoplaninA glycopeptide antibiotic with a similar mechanism of action and spectrum of activity to vancomycin used to treat various infections caused by gram-positive bacteria.
DB06402TelavancinAn antibacterial agent used in the treatment of complicated skin and skin structure infections and types of hospital-acquired bacterial pneumonia.
DB00685TrovafloxacinAn antibiotic used to treat gonorrhea and chlamydia.
DrugDrug NameTargetType
DB00479Amikacin30S ribosomal protein S12target
DB14879CefiderocolPenicillin-binding protein 3target
DB14879CefiderocolPenicillin-binding protein 1Atarget
DB14879CefiderocolPenicillin-binding protein 1Btarget
DB14879CefiderocolPenicillin-binding protein 2target
DB14879CefiderocolD-alanyl-D-alanine carboxypeptidase DacBtarget
DB14879CefiderocolMexAB-OprM efflux systemtransporter
DB14879CefiderocolSerum albumincarrier
DB14879CefiderocolCatecholate siderophore receptor Fiutransporter
DB14879CefiderocolColicin I receptortransporter
DB14879CefiderocolPutative outer membrane ferric siderophore receptortransporter
DB00438CeftazidimeSolute carrier family 22 member 6transporter
DB00438CeftazidimePeptidoglycan synthase FtsItarget
DB00438CeftazidimePenicillin-binding protein 1Atarget
DB00438CeftazidimePenicillin-binding protein 1Btarget
DB00438CeftazidimePenicillin-binding protein 2target
DB00438CeftazidimeSerum albumincarrier
DB04918CeftobiproleMecAtarget
DB04918CeftobiprolePenicillin-binding protein 2xtarget
DB04918CeftobiprolePeptidoglycan synthase FtsItarget
DB09050CeftolozanePenicillin-binding protein 1Btarget
DB09050CeftolozanePenicillin-binding protein 3target
DB09050CeftolozanePenicillin-binding proteintarget
DB09050CeftolozanePenicillin-binding protein 1Ctarget
DB09050CeftolozanePenicillin-binding protein 2target
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 2-alphatarget
DB00537CiprofloxacinCytochrome P450 1A2enzyme
DB00537CiprofloxacinCytochrome P450 3A4enzyme
DB00537CiprofloxacinCytochrome P450 3A5enzyme
DB00537CiprofloxacinCytochrome P450 3A7enzyme
DB00537CiprofloxacinP-glycoprotein 1transporter
DB00537CiprofloxacinPotassium voltage-gated channel subfamily H member 2target
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Btarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug resistance protein MdtKtarget
DB00537CiprofloxacinGyrase Atarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug and toxin extrusion protein 1transporter
DB00537CiprofloxacinMultidrug and toxin extrusion protein 2transporter
DB00537CiprofloxacinSerum albumincarrier
DB00319PiperacillinSolute carrier family 22 member 6transporter
DB00319PiperacillinPenicillin-binding protein 3target
DB00319PiperacillinPenicillin-binding protein 2Btarget
DB00319PiperacillinPenicillin-binding protein 2atarget
DB00319PiperacillinPenicillin-binding protein 1btarget
DB00319PiperacillinSolute carrier family 22 member 8transporter
DB09324SulbactamBeta-lactamasetarget
DB01606TazobactamBeta-lactamase TEMtarget
DB01606TazobactamSolute carrier family 22 member 6transporter
DB01606TazobactamSolute carrier family 22 member 8transporter
DB01606TazobactamBeta-lactamase Ohio-1target
DB01606TazobactamBeta-lactamase SHV-1target
DB06149TeicoplaninD-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycantarget
DB00685TrovafloxacinDNA gyrase subunit Atarget
DB00685TrovafloxacinDNA topoisomerase 4 subunit Atarget
DB00685TrovafloxacinDNA topoisomerase 2-alphatarget
DB00685TrovafloxacinCytochrome P450 1A2enzyme
DrugDrug NamePhaseStatusCount
DB09050Ceftolozane1Suspended1
DB01606Tazobactam1Suspended1
DB08816Ticagrelor1Completed1
DB14879Cefiderocol2Recruiting2
DB01111Colistimethate2Unknown Status1
DB06358Iclaprim2Terminated1
DB00512Vancomycin2Terminated1
DB09060Avibactam3Completed1
DB14879Cefiderocol3Completed2
DB00438Ceftazidime3Completed1
DB04918Ceftobiprole3Completed1
DB14733Ceftobiprole medocaril3Completed1
DB00803Colistin3Completed2
DB16704Durlobactam3Completed1
DB01598Imipenem3Completed2
DB01137Levofloxacin3Completed1
DB00601Linezolid3Completed1
DB00601Linezolid3Recruiting1
DB00760Meropenem3Completed3
DB00760Meropenem3Withdrawn1
DB11062Octisalate3Completed1
DB09535Octocrylene3Completed1
DB00319Piperacillin3Withdrawn1
DB01045Rifampicin3Completed1
DB09324Sulbactam3Completed1
DB01606Tazobactam3Withdrawn1
DB12107Vaborbactam3Completed1
DB12107Vaborbactam3Withdrawn1
DB09321Zinc oxide3Completed1
DB09060Avibactam4Not Yet Recruiting1
DB09060Avibactam4Recruiting1
DB00438Ceftazidime4Not Yet Recruiting1
DB00438Ceftazidime4Recruiting1
DB00878Chlorhexidine4Completed1
DB13831Potassium permanganate4Completed1
DB00635Prednisone4Active Not Recruiting1
DB00802AlfentanilNot AvailableCompleted1
DB00479AmikacinNot AvailableCompleted1
DB00513Aminocaproic acidNot AvailableCompleted1
DB00559BosentanNot AvailableCompleted1
DB01413CefepimeNot AvailableCompleted1
DB00878ChlorhexidineNot AvailableEnrolling by Invitation1
DB00369CidofovirNot AvailableCompleted1
DB00537CiprofloxacinNot AvailableCompleted1
DB00363ClozapineNot AvailableCompleted1
DB00828FosfomycinNot AvailableCompleted1
DB00502HaloperidolNot AvailableCompleted1
DB00598LabetalolNot AvailableCompleted1
DB00601LinezolidNot AvailableCompleted2
DB08815LurasidoneNot AvailableCompleted1
DB00959MethylprednisoloneNot AvailableCompleted1
DB01618MolindoneNot AvailableCompleted1
DB00607NafcillinNot AvailableCompleted1
DB01115NifedipineNot AvailableCompleted1
DB00497OxycodoneNot AvailableCompleted1
DB00312PentobarbitalNot AvailableCompleted1
DB00319PiperacillinNot AvailableCompleted1
DB00728RocuroniumNot AvailableCompleted1
DB00658SevelamerNot AvailableCompleted1
DB00421SpironolactoneNot AvailableCompleted1
DB01606TazobactamNot AvailableCompleted1
DB06402TelavancinNot AvailableCompleted1
DB00684TobramycinNot AvailableCompleted1
DB00302Tranexamic acidNot AvailableCompleted1
DB00512VancomycinNot AvailableCompleted3
DB01339VecuroniumNot AvailableCompleted1
DB00682WarfarinNot AvailableCompleted1
DB00246ZiprasidoneNot AvailableCompleted1
DB00425ZolpidemNot AvailableCompleted1