Vulvovaginal Candidiasis (DBCOND0032341)

Identifiers

Synonyms
Vulvovaginal Candidiases / Vulvovaginal Candidiasis, Genital / Vulvovaginal Candidiasis (VVC) / Candidiasis, Vulvovaginal / Vulvo-vaginal Candidiasis / Vulvovaginal candidiasis / Acute candidiasis of vulva and vagina / Candidiasis of vulva and vagina / Candidal vulvovaginitis (disorder) / Vulvovaginal candida

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Butoconazole
An imidazole antifungal used to treat vulvovaginal candidiasis.
Ciclopirox
A broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients.
Ibrexafungerp
A triterpene antifungal indicated in the treatment of vulvovaginal candidiasis and prevention of recurrent vulvovaginal candidiasis in post-menarchal patients.
Itraconazole
A triazole antifungal agent used to treat various fungal infections, such as blastomycosis and onychomycosis.
Ketoconazole
A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
Lidocaine
A local anesthetic used in a wide variety of superficial and invasive procedures.
Nystatin
A polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species.
Sertaconazole
A topical antifungal agent used in the treatment of interdigital tinea pedis in immunocompetent patients.
Sulfanilamide
A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans.
Terconazole
An antifungal drug used in the treatment of vulvovaginal candidiasis.
Tioconazole
An imidazole antifungal used to treat vulvovaginal candidiasis.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03064789
Epidemiological Study in Subjects With Vulvovaginal CandidiasesNo drug interventionsNot AvailableNot Availablecompleted
NCT03167957
Efficacy and Safety of Oral Encochleated Amphotericin B (CAMB) in the Treatment of Fluconazole-Resistant Vulvovaginal Candidiasistreatment2withdrawn
NCT06200389
Epidemiological Study of Vulvovaginal Candidiases Strain Types and Risk Factors Among Gynecological Outpatients in ChinaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05273333
Effect of Ultra-gyn® on Vulvovaginal CandidiasisNo drug interventionsotherNot Availableunknown_status
NCT04292704
A Protocol for the Role of Fractional CO2 Laser in Consolidation Treatment of Recurrent Vulvovaginal CandidiasistreatmentNot Availableunknown_status
NCT06411314
Efficacy and Safety of Natamycin and Lactulose Vaginal Suppositories in Treatment of Vulvovaginal Candidiasistreatment3completed
NCT03115073
ProF-001_Phase IIatreatment2 / 3completed
NCT02888197
Non-Interventional Extension to Investigate Recurrence of Vulvovaginal Candidiasis and Candida ColonizationNo drug interventionsNot AvailableNot Availablecompleted
NCT02251093
Study of the Efficacy and Tolerance of Intra-vaginal Treatment With a Total Freeze-dried Culture of Lcr Regenerans® in the Prevention of Relapses of Recurrent Vulvovaginal CandidiasisNo drug interventionsprevention3completed
NCT02971007
Safety and Efficacy of Oral Encochleated Amphotericin B (CAMB/MAT2203) in the Treatment of Vulvovaginal Candidiasis (VVC)treatment2completed
NCT04626258
Fluconazol Versus Medical Honey in the Treatment of Recurrent Vulvovaginal Candidiasistreatment4not_yet_recruiting
NCT02730494
Study Evaluating the Optimal Dosage for Equivalence Between Lcr Regenerans® Capsules and Tablets (Lactobacillus Rhamnosus Lcr35®) on the Vaginal Flora ColonisationNo drug interventionsother1completed
NCT05367089
The Effect of Medical Grade Honey Formulation (L-Mesitran) Administration on Recurrent Vulvovaginal Candidiasis Symptomstreatment3recruiting
NCT05059145
A Clinical Trial for Chlorhexidine as Treatment for Vulvovaginal Candidiasistreatment2recruiting
NCT02180828
Clotrimazole Vaginal Tablet vs Fluconazole for Severe Vulvovaginal Candidiasistreatment4completed
NCT02859493
Effect of Saccharomyces Cerevisiae on Vulvo-vaginal CandidiasisNo drug interventionssupportive_careNot Availableterminated
NCT06572488
Non-ablative Er:YAG for Recurrent CandidiasisNo drug interventionstreatmentNot Availablecompleted
NCT04930107
Vulvovaginal Candidiasis in Canadian Femalesbasic_science0recruiting
NCT02733432
RADIANT: CD101 vs Standard of Care in Subjects With Acute Vaginal Yeast Infectionstreatment2completed
NCT02248506
Epidemiological Study About the Evolution of Patients Treated for an Acute Episode of Vulvovaginal CandidiasisNo drug interventionshealth_services_research4completed
NCT01891331
A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Acute Vaginal Candidiasis (Yeast Infection)treatment2completed
NCT03975569
Study of the Vaginal Microbiota and the Potential of a Vaginal Probiotic Cream in Vaginal CandidosisNo drug interventionstreatmentNot Availablecompleted
NCT03075046
Use of 405nm Blue Light Emitting Diode in the Treatment of Women With Vulvovaginal Candidiasis: a Clinical TrialNo drug interventionstreatmentNot Availablerecruiting
NCT01293643
A Study to Compare the Efficacy and Safety of a Combination of Ketoconazole and Clindamycin Compared to Tetracycline/Amphotericin B Combination Cream for the Treatment of Bacterial Vaginosis and Vaginal Candidiasis (P08077)treatment3completed
NCT02345096
Effect of Saccharomyces Cerevisiae on Improving the Effectiveness of Conventional Treatment of Vulvo-vaginal CandidiasisNo drug interventionssupportive_careNot Availableterminated
NCT05507333
Clinical Performance of the Gedea Pessary in Adult Women With Vulvovaginal CandidiasisNo drug interventionstreatmentNot Availablecompleted
NCT00895453
Monthly Itraconazole Versus Classic Homeopathy for Treatment of Recurrent Vulvovaginal Candidiasis (RVVC)treatmentNot Availablecompleted
NCT00353561
Diabetes Mellitus and Vulvovaginal Candidiasistreatment3completed
NCT01926028
Safety, Tolerability, Immunogenicity and Efficacy of NDV-3A Vaccine in Preventing Recurrent Vulvovaginal CandidiasisNo drug interventionsprevention1 / 2completed
NCT05552378
Multi-Gyn FloraFem Study for Treatment of Vulvo Vaginal Candidiasis SymptomsNo drug interventionstreatmentNot Availablecompleted
NCT02907307
Efficacy, Safety LactiSal 1% Gel, LactSal 50 mg, Clotrimazole 100 mg Tablet in Treatment Vulvovaginal Candidiasistreatment3withdrawn
NCT02180100
Terconazole Vaginal Suppository vs Fluconazole for the Treatment of Severe Vulvovaginal Candidiasistreatment4completed
NCT02203942
Comparing NAAT Testing to Standard Methods for the Diagnosis of VaginitisNo drug interventionsNot AvailableNot Availablecompleted
NCT05399641
Ibrexafungerp for the Treatment of Complicated Vulvovaginal Candidiasistreatment3completed
NCT01144286
Arasertaconazole Nitrate Pessaries - Dose Finding Study for the Vulvovaginal Candidiasis (VVC) Treatmenttreatment2completed
NCT06397248
DeVEnIR: Defining Vulvovaginal Candidiasis - Elements of Infection and RemedyNo drug interventionsNot AvailableNot Availablerecruiting
NCT02866227
TOL-463 Phase 2 Study for VaginitisNo drug interventionstreatment2completed
NCT05895162
Zinc-containing Vaginal Gel and Oral Fluconazole for Vulvovaginal Candidiasis.treatmentNot Availablerecruiting
NCT05327192
VVC Sampling Study for Analysis ValidationNo drug interventionsNot AvailableNot Availablecompleted
NCT02242695
Comparative Efficacy Study of 10 mg Dequalinium Chloride (Fluomizin) in the Treatment of Vulvovaginal Candidiasistreatment4completed
NCT04208555
Comparison of Boric Acid vs. Terconazole in Treatment of RVVCtreatmentNot Availableunknown_status
NCT00803738
Safety and Equivalence of a Terconazole Vaginal Suppository (Test Product) Compared to the Reference Terconazole Vaginal Suppository in the Treatment of Vulvovaginal CandidiasistreatmentNot Availablecompleted
NCT03024502
Patients With Vulvovaginal Candidiasistreatment1 / 2unknown_status
NCT00755053
Comparative Efficacy of Ovule vs Tablettreatment3completed
NCT03761628
Clinical Performance of a Vaginal Pessary (pHyph) in Vulvovaginal CandidiasisNo drug interventionstreatmentNot Availablecompleted
NCT05079711
Comparative Performance of a Vaginal Yeast TestNo drug interventionsNot AvailableNot Availablerecruiting
NCT02679456
Safety and Efficacy of Oral Ibrexafungerp (SCY-078) vs. Oral Fluconazole in Subjects With Vulvovaginal Candidiasistreatment2completed
NCT05012852
Evaluation of VagiVitalAC for Treatment of Candida VulvovaginitisNo drug interventionstreatmentNot Availableunknown_status
NCT05753813
Exploring the Effects of an Intravaginal Lactic Acid Gel on the Vaginal Microbiomebasic_science0recruiting
NCT00194324
Effect of Exercise on Spread of the Miconozole Nitrate OVULE in the VaginaNot Available4completed
NCT05908682
Safety of Pregnant Subjects Exposed to Ibrexafungerp Including Infant OutcomesNo drug interventionsNot AvailableNot Availablerecruiting
NCT06480604
Effect of a Multi-strain Probiotic on Recurrent Vulvovaginal CandidiasisNo drug interventionspreventionNot Availablenot_yet_recruiting
NCT05031481
Efficacy and Safety of Different Doses of Venus Association in Patients With Vulvovaginal Candidiasis.treatment2withdrawn
NCT02150655
Study of the Microbiota, Metabolome, and Environmental Toxins in Relation to Reproductive Health in Rwandan Womenbasic_science0completed
NCT01806623
The Study Of Fluconazole For Vulvovaginal Candidiasistreatment3completed
NCT01497223
MGCD290 and Fluconazole Versus Fluconazole Alone for the Treatment of Moderate to Severe Vulvovaginal CandidiasisNo drug interventionstreatment2completed
NCT06450990
Efficacy, Safety, and Dose-response of a Live Biotherapeutic Product in Women With Acute Vaginal InfectionNo drug interventionstreatment1 / 2not_yet_recruiting
NCT01039584
A Randomized Study Evaluating the Therapeutic Equivalence of Two Butoconazole Nitrate Vaginal Cream, 2% FormulationstreatmentNot Availablecompleted