NCT05094661
Predictors of Non-invasive Respiratory Support Failure in COVID-19 Pneumonia No drug interventions treatment Not Available completed NCT04635267
Effects of Extravascular Lung Water on Prone Position Efficacy in Patients With ARDS No drug interventions Not Available Not Available unknown_status NCT04744090
Roflumilast as add-on Therapy in Early Cases of ARDS treatment 2 completed NCT02664090
Hemodynamic Assessment With Trans-esophageal Doppler (TED) During Prone Ventilation in ARDS Patients No drug interventions Not Available Not Available completed NCT01167621
Changes in Refractory Acute Respiratory Distress Syndrome (ARDS) Patients Under High Frequency Oscillation-ventilation No drug interventions Not Available Not Available completed NCT00000579
Acute Respiratory Distress Syndrome Clinical Network (ARDSNet) treatment 3 completed NCT01256333
Optimization of Arterial Oxygen Transport by Positive End-expiratory Pressure Variation in Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT04139733
Early Use of Prone Position in ECMO for Severe ARDS No drug interventions Not Available Not Available recruiting NCT03376854
Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS No drug interventions treatment 2 withdrawn NCT03424798
Measuring Heart and Lung Function in Critical Care No drug interventions Not Available Not Available unknown_status NCT01743105
Reproductibility of TM-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in the ER No drug interventions diagnostic Not Available completed NCT04297397
Personalised Simulation Technologies for Optimising Treatment in the Intensive Care Unit No drug interventions Not Available Not Available completed NCT03539783
Identifying PARDS Endotypes No drug interventions Not Available Not Available completed NCT01165528
Adaptive Support Ventilation in Acute Respiratory Distress Syndrome (ARDS) No drug interventions treatment Not Available unknown_status NCT00029328
Etanercept for Non-Infectious Lung Injury Following Bone Marrow Transplantation treatment 1 / 2 completed NCT00113685
Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury treatment Not Available completed NCT03712215
STUDY OF ELECTRICAL STIMULATION IN PULMONARY FUNCTION IN INTENSIVE CARE UNIT No drug interventions treatment Not Available completed NCT00429637
Continuous Exhaled Breath Condensate pH in Mechanically Ventilated Patients No drug interventions Not Available Not Available unknown_status NCT01992237
Measuring Energy Expenditure in ECMO (Extracorporeal Membrane Oxygenation) Patients No drug interventions Not Available Not Available unknown_status NCT00944437
Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet No drug interventions treatment Not Available terminated NCT00542737
Evaluating a Web-Based Ventilator Management Educational Program for Clinicians (The Lung Injury Knowledge Network [LINK] Study) No drug interventions Not Available Not Available unknown_status NCT00682500
Calfactant for Direct Acute Respiratory Distress Syndrome treatment 3 terminated NCT04778059
Safety and Efficacy of USB002 for Respiratory Distress Due to COVID-19 No drug interventions treatment 2 terminated NCT02759770
Risk Factors and Prediction Score of ARDS After Cardiac Surgery No drug interventions Not Available Not Available completed NCT01468142
Pulmonary Pathophysiology and Inflammatory Response in Patients Treated With Ecmo for Severe Respiratory Failure No drug interventions Not Available Not Available completed NCT03709199
Long Term Follow up of Children Enrolled in the REDvent Study No drug interventions Not Available Not Available recruiting NCT04028336
The Strategy of "Pulmonary Opening by Titration of Positive End-expiratory Pressure" Means of a Pulmonary Recruitment Maneuver in Patients With Acute Respiratory Distress Syndrome: for Which Patients? No drug interventions other Not Available terminated NCT02097641
Human Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome (START) treatment 2 completed NCT02622724
Efficacy and Safety of FP-1201-lyo (Interferon Beta-1a) in Patients Having Acute Respiratory Distress Syndrome (ARDS) treatment 3 terminated NCT01374022
ART - Alveolar Recruitment for Acute Respiratory Distress Syndrome Trial No drug interventions treatment Not Available completed NCT05604430
Pre-hospital Ventilation Clinical Study No drug interventions Not Available Not Available enrolling_by_invitation NCT00300248
Long-Term Results in Mechanically Ventilated Individuals With Acute Lung Injury/Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT00141726
Study of Enbrel (Etanercept) for the Treatment Sub-Acute Pulmonary Dysfunction After Allogeneic Stem Cell Transplant treatment 2 completed NCT00458926
Enhancing Utilization of Non-Invasive Positive Pressure Ventilation in Critical Care No drug interventions Not Available Not Available completed NCT02961166
Immunglobulin M Enriched Intra Venous Immunoglobulin (IVIG) Therapy in Adult Respiratory Distress Syndrom (ARDS) Patients Not Available Not Available completed NCT06159465
Utility of Defining ARDS and Past and Current Definitions of ARDS No drug interventions Not Available Not Available completed NCT03971331
The Value of Combined Critical Care Ultrasound and PAC Monitor Oriented Therapy Protocol to Patients of ARDS With ACP No drug interventions diagnostic Not Available unknown_status NCT00319631
Role of Vascular Endothelial Growth Factor (VEGF) in Acute Lung Injury/Adult Respiratory Distress Syndrome (ARDS) No drug interventions Not Available Not Available withdrawn NCT00416260
Combined High Frequency Oscillation and Tracheal Gas Insufflation for Severe Acute Respiratory Distress Syndrome No drug interventions treatment 1 / 2 completed NCT00004494
Phase I Study of Vasoactive Intestinal Peptide in Patients With Acute Respiratory Distress Syndrome and Sepsis treatment 1 completed NCT02252094
Ultra-protective Pulmonary Ventilation Supported by Low Flow ECCO2R for Severe ARDS No drug interventions treatment Not Available terminated NCT04382391
Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms No drug interventions treatment Not Available terminated NCT01716962
Effects of Positive End-expiratory Pressure and Tidal Volume on Fluid Responsiveness of Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available unknown_status NCT00217880
Significance of Biological Markers in Patients With Acute Lung Injury/Acute Respiratory Disease No drug interventions diagnostic Not Available completed NCT00609180
Early Versus Delayed Enteral Feeding and Omega-3 Fatty Acid/Antioxidant Supplementation for Treating People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN-Omega Study) No drug interventions treatment 3 terminated NCT04347980
Dexamethasone Treatment for Severe Acute Respiratory Distress Syndrome Induced by COVID-19 treatment 3 terminated NCT04710329
High-Dose Vitamin C Treatment in Critically Ill COVID-19 Patients Not Available Not Available completed NCT00157144
Australia and New Zealand Adult Extracorporeal Membrane Oxygenation (ECMO) Audit 2005 No drug interventions Not Available Not Available completed NCT04582201
Evaluate the Safety of agenT-797 in Participants With Moderate to Severe Difficulty Breathing Secondary to SARS-CoV-2 No drug interventions treatment 1 / 2 completed NCT03236272
Establishment of a Biomarkers-based Early Warning System of Acute Respiratory Distress Syndrome (ARDS) No drug interventions Not Available Not Available unknown_status NCT04157946
The Role of Morphological Phenotype in ARDS No drug interventions Not Available Not Available completed NCT00719446
Evaluating Health Outcomes and QOL After ALI Among Participants of the ALTA, OMEGA, EDEN, and SAILS ARDS Network Trials No drug interventions Not Available Not Available completed NCT03111212
Iloprost in Acute Respiratory Distress Syndrome treatment 3 completed NCT01391481
Perfluorocarbon (PFC) Inhalation Treatment of Acute Lung Injury/Acute Respiratory Distress Syndrome treatment 2 unknown_status NCT02370095
Treprostinil Sodium Inhalation for Patients At High Risk for ARDS prevention 2 terminated NCT03969914
PEEP-induced Changed in RRI as Physiological Background of Ventilator-induced Kidney Injury No drug interventions Not Available Not Available completed NCT00112164
Activated Protein C to Treat Acute Lung Injuries treatment 2 terminated NCT06489379
High Flow Nasal Oxygen for Acute Hypoxemic Respiratory Failure in the Emergency Room No drug interventions treatment Not Available not_yet_recruiting NCT04345887
Spironolactone in Covid-19 Induced ARDS Not Available Not Available completed NCT02273687
Time-motion-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in Emergency Department No drug interventions diagnostic Not Available completed NCT04508933
Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and "Typical"ARDS Patients No drug interventions Not Available Not Available withdrawn NCT00351533
A Phase II Randomized Trial of Fish Oil in Patients With Acute Lung Injury (ALI) treatment 2 completed NCT01070654
Inflammatory Effects of a Lung Recruitment Manoeuvre No drug interventions treatment Not Available unknown_status NCT03818854
Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome treatment 2 completed NCT02439151
New Lung Ventilation Strategies Guided by Transpulmonary Pressure in VV-ECMO for Severe ARDS No drug interventions treatment Not Available completed NCT04395105
Dexamethasone for COVID-19 Related ARDS: a Multicenter, Randomized Clinical Trial treatment 3 terminated NCT06203405
The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial treatment Not Available recruiting NCT00434993
Drug Study of Albuterol to Treat Acute Lung Injury treatment 2 / 3 terminated NCT04228471
Early PReserved SPONtaneous Breathing Activity in Mechanically Ventilated Patients With ARDS (PReSPON) No drug interventions treatment Not Available unknown_status NCT00233207
IC14 Antibodies to Treat Individuals With Acute Lung Injury No drug interventions treatment 2 terminated NCT00201409
A Randomized Trial of GM-CSF in Patients With ALI/ARDS No drug interventions treatment 2 completed NCT01990456
Strategies for Optimal Lung Ventilation in ECMO for ARDS: The SOLVE ARDS Study No drug interventions supportive_care Not Available unknown_status NCT02342756
Esophageal Pressure-Guided Optimal PEEP/mPaw in CMV and HFOV: The EPOCH Study No drug interventions treatment Not Available unknown_status NCT04520815
Prevalence and Kinetics of Diaphragmatic Dysfunction in Elderly Patients With Acute Respiratory Distress No drug interventions Not Available Not Available unknown_status NCT02112500
Mesenchymal Stem Cell in Patients With Acute Severe Respiratory Failure No drug interventions treatment 2 unknown_status NCT03188770
Practice of Ventilation in Middle-Income Countries No drug interventions Not Available Not Available completed NCT02892799
Non-invasive Fluid Management No drug interventions treatment Not Available unknown_status NCT00094406
Carbon Monoxide to Prevent Lung Inflammation treatment 1 completed NCT06174636
Lung Overdistension and Abdominal Pressure Rise No drug interventions diagnostic Not Available recruiting NCT06430619
Can Novel Oxygenation Indices Guide the Diagnosis of Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT02732041
Asynchrony During Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT06199141
Multi-drug Resistant Gram-negative Bacteria and Veno-venous Extracorporeal Membrane Oxygenation (ECMO) No drug interventions Not Available Not Available completed NCT00267241
Effects of Different Assisted Mechanical Ventilation in Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS) Patients No drug interventions treatment Not Available completed NCT04545424
Trial of Therapeutic Hypothermia in Patients With ARDS No drug interventions treatment 2 recruiting NCT00605696
Early Insulin and Development of ARDS prevention 2 completed NCT03788096
Peer Support for Post Intensive Care Syndrome Self-Management No drug interventions supportive_care Not Available unknown_status NCT00431158
ARDSnet Protocol vs. Open Lung Approach in ARDS No drug interventions treatment Not Available completed NCT04516486
Coronavirus Studied by Metagenomics in ARDS COVID-19 Patients No drug interventions Not Available Not Available unknown_status NCT00308022
Comparison Study of High Frequency Percussive Ventilation With Conventional Ventilation No drug interventions treatment 2 / 3 withdrawn NCT05083130
Awake Prone Positioning in Moderate to Severe COVID-19 No drug interventions supportive_care Not Available completed NCT00883948
Early Versus Delayed Enteral Feeding to Treat People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN Study) No drug interventions treatment 3 completed NCT04388826
COVID-19 Treatment of Severe Acute Respiratory Syndrome With Veru-111 treatment 2 completed NCT00465374
A Validation/Interventional Study on Stress Index in Predicting Mechanical Stress in ARDS Patients No drug interventions treatment 3 unknown_status NCT04378582
Characteristics and Outcomes of Patients With COVID-19 Admitted to the ICU No drug interventions Not Available Not Available completed NCT02895373
PGE1 as Additive Anticoagulant in ECMO-Therapy treatment 2 terminated NCT04012073
Individualized Positive End-expiratory Pressure Guided by End-expiratory Lung Volume in the Acute Respiratory Distress Syndrome No drug interventions treatment 3 recruiting NCT03337373
The Study of Pharmacokinetics and Pharmacodynamics of Cisatracurium basic_science 4 completed NCT00605527
Understanding the Role of Genes and Biomarkers in the Inflammation and Blood Clotting Process in Children With Acute Lung Injury No drug interventions Not Available Not Available completed NCT03202394
Evaluation of Safety & Efficacy of BIO-11006 Inhalation Solution in Patients With ARDS treatment 2 completed NCT00036062
A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung Injury treatment 1 / 2 completed NCT05715762
Determine the Effects of Prone Positioning and NO in COVID-19 ARDS by EIT No drug interventions Not Available Not Available recruiting NCT00236262
Effect of Positive Expiratory Pressure on Right Ventricular Function in Patients With Respiratory Distress Syndrome No drug interventions treatment Not Available completed NCT04510662
Telmisartan in Respiratory Failure Due to COVID-19 treatment 2 completed NCT00357929
Weaning From Mechanical Ventilation Using Permissive Hypercarbia No drug interventions treatment Not Available terminated NCT01461889
INR-Triggered Transfusion In GI Bleeders From ER No drug interventions prevention 3 terminated NCT03368092
Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma treatment 3 recruiting NCT02799940
Abnormalities in Lung Computed Tomography and Physiological Alterations in Patients With Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT00455767
Safety and Efficacy Study of Depelestat in Acute Respiratory Distress Syndrome (ARDS) Patients No drug interventions treatment 2 completed NCT03807804
Efficacy and Safety Study of HLCM051(MultiStem®) for Pneumonic Acute Respiratory Distress Syndrome No drug interventions treatment 2 completed NCT01119872
Pilot Study of Positive-End Expiratory Pressure in Acute Respiratory Distress Syndrome No drug interventions treatment Not Available completed NCT05210881
Weaning From Nasal High Flow Therapy No drug interventions Not Available Not Available completed NCT00399581
Comparison of Two Methods of High Frequency Oscillatory Ventilation in Individuals With Acute Respiratory Distress Syndrome No drug interventions treatment 2 completed NCT00548795
Viral-Related Neutrophil Response and Condition Severity in People With ARDS No drug interventions Not Available Not Available completed NCT05081895
Ventilation and Perfusion in the Respiratory System No drug interventions Not Available Not Available enrolling_by_invitation NCT01601223
Local Assessment of Ventilatory Management During General Anesthesia for Surgery No drug interventions Not Available Not Available completed NCT01464853
Effect of Enteral Nutrition Support for Critically Ill Patients No drug interventions treatment 3 terminated NCT03715647
Correlation of Survival in Puerperae by Electrical Impedance Tomography No drug interventions Not Available Not Available completed NCT04106128
Prevalence, Impact and Reversibility of Acute Diaprhagmatic Dysfunction in Acute Respiratory Detresse No drug interventions diagnostic Not Available completed NCT00155779
ACE Gene Polymorphism and ARDS Outcome No drug interventions Not Available Not Available completed NCT01195428
Simvastatin Effect on the Incidence of Acute Lung Injury/Adult Respiratory Distress Syndrome (ALI/ARDS) prevention Not Available withdrawn NCT00465309
Protective Ventilation With Carbon Dioxide (CO2) -Removal Technique in Patients With Adult Respiratory Distress Syndrome (ARDS) No drug interventions treatment 3 completed NCT00793013
Airway Pressure Release Ventilation (APRV) Compared to ARDSnet Ventilation No drug interventions treatment 2 withdrawn NCT01722422
Hyperoxia and Hypertonic Saline in Septic Shock No drug interventions treatment Not Available terminated NCT00314548
Inhaled Prostacyclin for Adult Respiratory Distress Syndrome (ARDS) and Pulmonary Hypertension treatment Not Available completed NCT01038531
Biomarkers of Lung Injury With Low Tidal Volume Ventilation Compared With Airway Pressure Release Ventilation No drug interventions treatment Not Available terminated NCT01083355
Assessing Respiratory Variability During Mechanical Ventilation in Acute Lung Injury (ALI) No drug interventions Not Available Not Available withdrawn NCT01901354
Acute Lung Injury Ventilator Evaluation (ALIVE) No drug interventions treatment Not Available terminated NCT01769053
Variable Pressure Support Trial No drug interventions treatment Not Available terminated NCT02804945
Mesenchymal Stem Cells (MSCs) for Treatment of Acute Respiratory Distress Syndrome (ARD) in Patients With Malignancies No drug interventions treatment 1 completed NCT06513949
Anti-CD14 Treatment With IC14 in Hospitalized ARDS Patients treatment 2 not_yet_recruiting NCT04390139
Efficacy and Safety Evaluation of Mesenchymal Stem Cells for the Treatment of Patients With Respiratory Distress Due to COVID-19 treatment 1 / 2 completed NCT04079426
Tetracycline to Limit the Innate Immune Response in Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available unknown_status NCT01667666
Clinical Trial of Nebulized Hypertonic Saline to Attenuate Post-Traumatic Acute Lung Injury No drug interventions prevention 1 terminated NCT03946150
PaO2/FiO2*PEEP (P/FP) Ratio and Mortality in Acute Respiratory Distress Syndrome. No drug interventions Not Available Not Available completed NCT05124197
Extended Prone Position Duration COVID-19-related ARDS: a Retrospective Study No drug interventions Not Available Not Available completed NCT05991778
Bioelectrical Impedance in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients No drug interventions Not Available Not Available completed NCT03225807
Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure No drug interventions Not Available Not Available completed NCT05795465
A Study of GEn-1124 in Subjects With Acute Respiratory Distress Syndrome (ARDS) No drug interventions treatment 2 recruiting NCT06188195
Establishment and Evaluation of Prenatal Prevention and Treatment Strategy for NARDS prevention Not Available not_yet_recruiting NCT05056090
Effect of Prone Positioning on Mortality in Patients With Mild to Moderate Acute Respiratory Distress Syndrome. No drug interventions treatment Not Available recruiting NCT03763890
Post- End- Expiratory Pressure Affect the Alveolar Heterogeneity in Moderate and Sever ARDS Patients No drug interventions Not Available Not Available unknown_status NCT01967602
Biomarker of Lung Injury in ARDS Patients Receiving ECMO Support No drug interventions Not Available Not Available unknown_status NCT06521502
The APS Phenotyping Study No drug interventions Not Available Not Available recruiting NCT03245684
Assisted or Controlled Ventilation in Ards (Ascovent) No drug interventions treatment Not Available unknown_status NCT04402879
CORONA (COvid pRONe hypoxemiA): Prone Positioning for Hypoxemic COVID-19 Patients With Do-not-intubate Goals No drug interventions treatment Not Available unknown_status NCT04692779
A Prospective Clinical Study to Explore Response to Prone Positioning in ARDS Patients No drug interventions Not Available Not Available completed NCT05384379
Efficacy and Safety Evaluation of BZ371B in ARDS Patients No drug interventions treatment 0 terminated NCT05219643
Effect of Nava on Weaning Outcome in Patients With Mechanical Ventilation No drug interventions treatment Not Available unknown_status NCT05341687
Prognostic Value of Respiratory System Compliance Under VV-ECMO on 180-day Mortality in COVID-19 ARDS. No drug interventions Not Available Not Available completed NCT05080933
ECMO for COVID-19 vs Influenza A H1N1 Associated ARDS No drug interventions Not Available Not Available completed NCT04067154
Gas Exchange and CT Effects of PEEP in ARDS No drug interventions supportive_care Not Available completed NCT04607551
PRONing to Facilitate Weaning From ECMO in Patients With Refractory Acute Respiratory Distress Syndrome No drug interventions other Not Available completed NCT04597853
Assessment of Lung Mechanics in COVID-19 Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available unknown_status NCT03567577
Safety and Preliminary Efficacy of Sequential Multiple Ascending Doses of Solnatide to Treat Pulmonary Permeability Oedema in Patients With Moderate-to-severe ARDS treatment 2 recruiting NCT05947747
Safety and Efficacy of EXO-CD24 in Preventing Clinical Deterioration in Patients With Mild-Moderate ARDS No drug interventions treatment 2 recruiting NCT02644798
Nucleotide Polymorphism in ARDS Outcome No drug interventions Not Available Not Available completed NCT00202098
Effects of Variable Ventilation on Respiratory System of Acute Respiratory Distress Syndrome (ARDS) Patients No drug interventions treatment Not Available completed NCT04519398
Investigating the Involvement of ACE and Angiotensinogen Genes' Polymorphism Along With Other Thrombophilic Genotypes in Severe Forms of COVID-19 With/Without Thrombotic Events No drug interventions Not Available Not Available unknown_status NCT04577105
Risk Factors and Computed Tomography Findings in COVID-19. No drug interventions Not Available Not Available completed NCT02510105
Tomodensitometric Study of Pulmonary Effects of Intrapulmonary Percussive Ventilation in ARDS Patients No drug interventions treatment Not Available unknown_status NCT04452097
Use of hUC-MSC Product (BX-U001) for the Treatment of COVID-19 With ARDS treatment 1 / 2 not_yet_recruiting NCT04396197
Physical Activity Levels in COVID-19 Patients Admitted to Intensive Care No drug interventions Not Available Not Available completed NCT03076983
Assessment of the Capability of PulmoVista 500 to Continuously Monitor Changes of Ventilation Over Time No drug interventions Not Available Not Available completed NCT04355728
Use of UC-MSCs for COVID-19 Patients treatment 1 / 2 completed NCT04347928
Respiratory and Hemodynamic Changes Induced in Mechanically Ventilated Patients for COVID-19 No drug interventions Not Available Not Available completed NCT04395911
Safety and Efficacy of SCD in AKI or ARDS Patients Associated With COVID-19 Infections No drug interventions treatment Not Available completed NCT04401111
One-year Outcomes in Survivors of the Severe COVID-19 Pneumonia (CO-Qo-ICU) No drug interventions Not Available Not Available recruiting NCT04468971
REgulatory T Cell infuSion fOr Lung Injury Due to COVID-19 PnEumonia treatment 1 completed NCT04530188
Effects of Sevoflurane on Extravascular Lung Water and Pulmonary Vascular Permeability in Patients With ARDS treatment 3 unknown_status NCT04406688
Prediction of Acute Kidney Injury in Patients With COVID-19 No drug interventions Not Available Not Available completed NCT03227107
The Evaluation of NETs, Caspase-1 and Cytokines in ARDS Patients No drug interventions Not Available Not Available unknown_status NCT06514209
Effect of Different Depths of Neuromuscular Blockade on Respiratory Mechanics in Patients With Moderate-severe Acute Respiratory Distress Syndrome treatment Not Available recruiting NCT06036056
NMR Based Metabolomics Kinetics in ARDS Patients No drug interventions Not Available Not Available recruiting NCT04366856
PROne Positioning in coVID-19 Oxygeno-dependent Patients in Spontaneous Ventilation (PROVID Study) No drug interventions treatment Not Available completed NCT04412356
Timing of Tracheotomy in Covid-19 Patients No drug interventions treatment Not Available completed NCT04035915
Comparison Between Limited Driving Pressure Ventilation and Conventional Mechanical Ventilation Strategies in Medical Intensive Care Patients With Acute Respiratory Failure No drug interventions treatment Not Available completed NCT01742715
Three Methods for Best PEEP Determination Compared With PEEP Determination Guided by Adult Respiratory Distress Syndrome (ARDS) Network No drug interventions treatment Not Available unknown_status NCT06494215
Comparison of Different Methods to Calculate Pendelluft by Electrical Impedance Tomography in Mechanically Ventilated Patients No drug interventions diagnostic Not Available recruiting NCT04366115
Evaluating AVM0703 for Treatment of COVID-19 or Influenza-mediated ARDS treatment 1 not_yet_recruiting NCT04445337
Stellate Ganglion Blockade in COVID-19 Positive Patients No drug interventions treatment Not Available completed NCT04764032
Right Ventricular Dysfunction in Ventilated Patients With COVID-19 No drug interventions Not Available Not Available unknown_status NCT06067152
REcruitment MAneuvers and Mechanical Ventilation Guided by EIT in pARDS No drug interventions supportive_care Not Available recruiting NCT01289600
Mechanical Ventilation and Respiratory Muscle Work of Breathing in Acute Respiratory Distress Syndrome (ARDS) Patients No drug interventions treatment Not Available completed NCT04357275
The RIsk Stratification in COVID-19 Patients in the ICU Registry No drug interventions Not Available Not Available active_not_recruiting NCT05058742
Non-invasive Nervus Vagus Stimulation in Patients With COVID-19 and ARDS No drug interventions prevention Not Available recruiting NCT04493242
Extracellular Vesicle Infusion Treatment for COVID-19 Associated ARDS No drug interventions treatment 2 completed NCT04694742
Ventilatory Efficiency in Critically Ill COVID-19 Patients No drug interventions Not Available Not Available unknown_status NCT05578742
V/Q Matching Variations With PEEP in ARDS According to Compliance-based Phenotypes (France) No drug interventions treatment Not Available not_yet_recruiting NCT05408442
Role of Pulmonary Perfusion on Tolerance to Supine Position in Patients With ARDS No drug interventions Not Available Not Available completed NCT04351906
Low-flow Extracorporeal Carbon Dioxide Removal in COVID-19-associated Acute Respiratory Distress Syndrome No drug interventions treatment Not Available recruiting NCT05098106
PLAIAR-Trial: Platelets in Inflammation and Resolution No drug interventions Not Available Not Available unknown_status NCT03237806
Effects of Sedation on Transpulmonary Pressure and Lung Homogenous No drug interventions screening Not Available completed NCT04474249
Follow-up of Critical COVID-19 Patients No drug interventions Not Available Not Available unknown_status NCT06242236
Comparison of Guiding Sedation Level by Respiratory Effort Versus Usual Care in Mechanically Ventilated Patients: A Randomized Controlled Trial (EFFORT-GUIDE Trial 2) No drug interventions treatment Not Available recruiting NCT04873336
Closed Loop Ventilation in Patients With COVID-19 No drug interventions Not Available Not Available completed NCT05281536
Effects of Trunk Postural Change on CO2 Removal Efficiency in ARDS Patients: Quasi-experimental Study No drug interventions supportive_care Not Available completed NCT04556513
Functional Recovery From Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19: Influence of Socio-Economic Status No drug interventions Not Available Not Available completed NCT04435613
Clinical and Physiological Assessment of a Nearly Ultra-protective Lung Ventilation Strategy: A Quasi-experimental Preliminary Study in ARDS Patients No drug interventions other Not Available completed NCT04174313
Ventilator-induced Lung Injury Vortex in Patients With SARS-CoV-2 No drug interventions Not Available Not Available completed NCT04383613
Prone Positioning for Patients on General Medical Wards With COVID19 No drug interventions other Not Available unknown_status NCT00258518
Respiratory Mechanics and Pleural Effusion No drug interventions Not Available Not Available completed NCT03764319
Low Frequency, Ultra-low Tidal Volume Ventilation in Patients With ARDS and ECMO No drug interventions treatment Not Available completed NCT05354141
Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS) No drug interventions treatment 3 recruiting NCT02945917
Positive End-expiratory Pressure and Esophageal Catheter Optimal Calibration Volume in ARDS Patients No drug interventions Not Available Not Available unknown_status NCT05228717
Point-of-care Lung Ultrasound (POCUS)-Integrated Study of Admitted Patients With COVID-19 No drug interventions Not Available Not Available unknown_status NCT04377334
Mesenchymal Stem Cells (MSCs) in Inflammation-Resolution Programs of Coronavirus Disease 2019 (COVID-19) Induced Acute Respiratory Distress Syndrome (ARDS) No drug interventions treatment 2 unknown_status NCT05591924
Early Severe Illness TrAnslational BioLogy InformaticS in Humans No drug interventions Not Available Not Available not_yet_recruiting NCT04360096
Inhaled ZYESAMIâ„¢ (Aviptadil Acetate) for the Treatment of Severe COVID-19 treatment 2 / 3 terminated NCT06093958
Paradoxical Response to Chest Wall Loading in Mechanically Ventilated Patients No drug interventions diagnostic Not Available withdrawn NCT06225258
Xanthohumol as an Adjuvant in the Treatment of Septic Shock No drug interventions treatment 2 recruiting NCT06083363
Longitudinal Recovery Trajectories After an Acute Respiratory Distress Syndrome, a New Understanding No drug interventions Not Available Not Available recruiting NCT06072222
Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation treatment 1 / 2 completed NCT06511622
Impact of Immune Status on Secondary Infections in Patients With Acute Respiratory Failure No drug interventions Not Available Not Available recruiting NCT06541522
Impact of Belt Position on the Results of PEEP Titration by EIT During ARDS No drug interventions other Not Available not_yet_recruiting NCT05007457
The Effectiveness of Respiratory Tele-rehabilitation After COVID-19 Pneumonia Related: a Randomized Controlled Trial No drug interventions treatment Not Available unknown_status NCT04412057
Clinical Trial to Evaluate CERC-002 in Adults With COVID-19 Pneumonia and Acute Lung Injury treatment 2 completed NCT04215666
Diagnostic Criteria of ARDS at High Altitudes in Western China No drug interventions Not Available Not Available unknown_status NCT04881266
Long-Term Functional, Quality-of-Life, Neuropsychological and Cognitive Outcomes in COVID-19 Critical Illness Survivors No drug interventions Not Available Not Available unknown_status NCT02070666
Preventive Strategies in Acute Respiratory Distress Syndrome (ARDS) No drug interventions prevention Not Available terminated NCT05708365
Generating Evidence in ECMO Ventilation Strategies No drug interventions other Not Available recruiting NCT06038682
Monitoring Anticoagulation in Patients on ECMO for Severe Lung Failure Not Available Not Available completed NCT04641182
Prone Position for Nonintubated Patients With COVID-19 and Hypoxemic Respiratory Failure No drug interventions Not Available Not Available completed NCT04653831
Treatment With Pirfenidone for COVID-19 Related Severe ARDS treatment Not Available completed NCT05406427
Monitorings the Physiological Mechanism of Airway Pressure Release Ventilation in ARDS Patients by EIT No drug interventions Not Available Not Available unknown_status NCT06006676
IMV to Accelerate Recovery of Lung Function in Veno-venous Extracorporeal Membrane Oxygenation; Lung Rest Or Moderate Mechanical Ventilation in ECMO No drug interventions basic_science Not Available recruiting NCT05225194
Long-term Impact of COVID-19 Among COVID-19 Patients With Acute Respiratory Distress Syndrome in Brazil No drug interventions Not Available Not Available unknown_status NCT04996394
"Effects of Neuromuscular Blocking Agents on End Expiratory Lung Volume During Moderate-severe ARDS" No drug interventions Not Available Not Available completed NCT05464680
Pulmonary Diffusion of Antibiotics in Patients Admitted for ARDS Following SARS-CoV-2 Pneumonia No drug interventions other Not Available recruiting NCT02560129
MICU Recovery Clinic No drug interventions Not Available Not Available completed NCT03227289
Acute Respiratory Distress Syndrome(ARDS) in Neonates No drug interventions Not Available Not Available recruiting NCT04505592
Tenecteplase in Patients With COVID-19 treatment 2 completed NCT02638844
Assessment of Right Ventricular 2d-strain in Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT04262440
The Effect of Caloric Supplement in the Clinical Outcomes in Acute Lung Injury Patients No drug interventions Not Available Not Available unknown_status NCT04391140
Prone Positioning and High-flow Nasal Cannula in COVID-19 Induced ARDS No drug interventions supportive_care Not Available unknown_status NCT05076240
FilmArray® and Management of Ventilator Associated Pneumonia in COVID-19 ARDS No drug interventions Not Available Not Available completed NCT04553367
Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation treatment 1 / 2 completed NCT05207267
Driving Pressure Guided VT in ARDS Patients No drug interventions treatment Not Available completed NCT04492501
Investigational Treatments for COVID-19 in Tertiary Care Hospital of Pakistan treatment Not Available completed NCT04365101
Natural Killer Cell (CYNK-001) Infusions in Adults With COVID-19 treatment 1 / 2 unknown_status NCT03616704
Effects of Different Driving Pressure on Lung Stress, Strain and Mechanical Power in Patients With Moderate to Severe ARDS No drug interventions Not Available Not Available unknown_status NCT01825304
The Study of Using Esophageal Pressure to Guide the PEEP Setting in Abdominal Hypertension Patients Who Undergoing Mechanical Ventilation No drug interventions treatment 4 unknown_status NCT03341572
The Effect of Positive End Expiratory Pressure on Central Venous Pressure Among Patients With Different Lung Compliance No drug interventions supportive_care Not Available unknown_status NCT05089968
Ventilation Associated Pneumonia and Covid-19 No drug interventions Not Available Not Available completed NCT04407468
Awake Prone Positioning and Oxygen Therapy in Patients With COVID-19 No drug interventions Not Available Not Available completed NCT04475068
Postural Recruitment Maneuver in Patients With Acute Respiratory Distress Syndrome Due to COVID-19 Infection No drug interventions Not Available Not Available completed NCT01668368
Goal Directed Mechanical Ventilation Aimed at Optimal Lung Compliance No drug interventions treatment Not Available unknown_status NCT04386369
Evaluation of Airway Pressure Release Ventilation in COVID-19 ARDS No drug interventions Not Available Not Available completed NCT06326112
Role of Active Deresuscitation After Resuscitation: treatment 2 not_yet_recruiting NCT04725110
Direct Topical Lung T3 Treatment to Improve Outcome & Sequelae of COVID-19 Acute Respiratory Distress Syndrome No drug interventions treatment 2 not_yet_recruiting NCT05137795
Inhaled ZYESAMI (Aviptadil Acetate) for Treatment of Severe COVID-19 treatment 3 withdrawn NCT05371314
Artificial Intelligence in Categorizing the Severity of Oxygenation by Incorporating the PEEP Into the Definition of ARDS in Ventilated Patients No drug interventions Not Available Not Available unknown_status NCT03200314
Blood Recirculation and vvECMO No drug interventions Not Available Not Available completed NCT04918914
Critical Care Results of SARS-CoV-2 ARDS by Dapsone and Standard COVID-19 Treatment treatment 0 unknown_status NCT05453214
Mineralocorticoid Use in COVID-19 Patients treatment 3 completed NCT03480555
Replacing Protein Via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients No drug interventions other Not Available completed NCT04536350
Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS treatment 2 terminated NCT04199650
Definition of ARDS in Qinghai Province: Verification of Berlin Definition Plateau Criteria No drug interventions Not Available Not Available unknown_status NCT04667923
Noninvasive Ventilation in Moderate-to-severe COVID-19-associated Acute Respiratory Distress-syndrome No drug interventions Not Available Not Available completed NCT04196738
Comparison of Volume Assist Control, Dual Mode and Airway Pressure Release Ventilation. No drug interventions other Not Available completed NCT04358003
Plasma Adsorption in Patients With Confirmed COVID-19 No drug interventions treatment Not Available completed NCT01737190
PEEP Guided by Esophageal Balloon Measurement and Its Effect on Recruitment Maneuver No drug interventions treatment Not Available unknown_status NCT04365764
Effect of Treatments in Patients Hospitalized for Severe COVID-19 Pneumonia: a Multicenter Cohort Study No drug interventions Not Available Not Available completed NCT05781802
V/Q Matching in Pressure Support Ventilation No drug interventions Not Available Not Available recruiting NCT04663802
Implementation of Nudges to Promote Utilization of Low Tidal Volume Ventilation (INPUT) Study No drug interventions health_services_research Not Available completed NCT02885584
Conventional Mechanical Ventilation and High Frequency Percussive Ventilation: Comparison of Their Effects on Alveolar Recruitment and Distension by CT-scan in Early ARDS Patients No drug interventions supportive_care Not Available unknown_status NCT05515484
Improvement of Lung and Thoracic Compliance in ARDS Patients in Prone Position by Using Inflatable Air Bag No drug interventions other Not Available unknown_status NCT03140579
Effect of PEEP on Lung Recruitment and Homogeneity Over Time in Moderate to Severe ARDS No drug interventions Not Available Not Available withdrawn NCT04909879
Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells for Non-COVID-19 Acute Respiratory Distress Syndrome No drug interventions treatment 2 withdrawn NCT04818554
Epidemiology and Prognosis of ARDS After Pulmonary Resection Surgery No drug interventions Not Available Not Available unknown_status NCT04570254
Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19 treatment Not Available completed NCT03768154
Prone Positioning and Spontaneous Breathing No drug interventions treatment 1 unknown_status NCT02543554
ED Lung Protective Ventilation to Reduce Complications No drug interventions Not Available Not Available completed NCT04455451
Intensive Care Therapy of Covid-19 Disease in Germany No drug interventions Not Available Not Available completed NCT02056977
PEEP Levels Selected by PEEP Titration and PEEP Levels Routinely Used in Post-operative Cardiac Patients With Hypoxemic Respiratory Failure No drug interventions treatment Not Available unknown_status NCT04346277
Compassionate Use Open-Label Anti-CD14 Treatment in Patients With SARS-CoV-2 (COVID-19) No drug interventions Not Available Not Available no_longer_available NCT04367077
MultiStem Administration for COVID-19 Induced ARDS (MACoVIA) treatment 2 / 3 unknown_status NCT05150847
Prone Positioning in COVID-19 Patients No drug interventions screening Not Available unknown_status NCT04728698
Study of Intravenous Administration of Allogeneic Adipose-Derived Mesenchymal Stem Cells for COVID-19-Induced Acute Respiratory Distress No drug interventions treatment 2 withdrawn NCT02265198
Relationship of Pulmonary Contusion to Pulmonary Inflammation and Incidence of Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT01881061
Lung Sonography in Patients With Acute Respiratory Distress Syndrome in Intensive Care Unit No drug interventions Not Available Not Available completed NCT04778228
Driving Pressure as a Predictor of Mortality in Acute Respiratory Distress Syndrome Patients No drug interventions Not Available Not Available unknown_status NCT04581811
Prolonged Prone Positioning for COVID-19-induced Acute Respiratory Distress Syndrome (ARDS) No drug interventions treatment Not Available completed NCT02054611
The Educational ARDS Diagnosis Study No drug interventions diagnostic Not Available completed NCT04406493
Monitoring COVID-19 Patients' Lung Fluid Using Impedance Technique No drug interventions diagnostic Not Available unknown_status NCT03120793
ARDS Esophageal Balloon Pressure Changes With Positioning Study No drug interventions Not Available Not Available terminated NCT00656071
Retrospective Postoperative ARDS Study at Vanderbilt University No drug interventions Not Available Not Available completed NCT06179771
Pilot Study on HA380 Column Use in Critically Ill Patients Receiving Extracorporeal Support. No drug interventions treatment Not Available not_yet_recruiting NCT03447288
Incidence of Dyssynchronies in Early ARDS No drug interventions Not Available Not Available unknown_status NCT04794088
Intravenous Imatinib in Mechanically Ventilated COVID-19 Patients treatment 2 terminated NCT03498807
A Comparison of Optimal PEEP Determination Guided by EIT and Conventional Protective Ventilation Tool in ARDS Patients No drug interventions treatment Not Available completed NCT06564207
Fostamatinib for Treating Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Adults treatment 2 not_yet_recruiting NCT04659109
Glenzocimab in SARS-Cov-2 Acute Respiratory DistrEss syNdrome Related to COVID-19 treatment 2 completed NCT05336656
Assessment of Analgesics and Sedatives in Mechanically Ventilated Patients With COVID-19 No drug interventions Not Available Not Available completed NCT05092737
Physiological Response to Prone Position in COVID-19 Associated Acute Respiratory Distress Syndrome (ARDS) No drug interventions Not Available Not Available completed NCT05531032
HRQOL of Life After ECMO Due to COVID-19. No drug interventions health_services_research Not Available recruiting NCT04953052
A Randomized Study to Investigate the Effect of Intravenous Imatinib on the Amount of Oxygen in the Lungs and Blood of Adults With COVID-19 Needing Mechanical Ventilation and Supportive Care. treatment 2 withdrawn NCT04366752
Thrombo Embolic Events in Critical Care Patients With Covid-19 Serious Acute Pneumopathy No drug interventions Not Available Not Available completed NCT04473300
Assessment of Lung Recruitablity of Acute Respiratory Distress Syndrome With SARS-CoV-2 Pneumonia by Electrical Impedance Tomography No drug interventions Not Available Not Available completed NCT05166759
Incidence and Clinical Characteristics of Pulmonary Hypertension Secondary to ARDS in the Highland No drug interventions Not Available Not Available unknown_status NCT05216575
Almitrine in COVID-19 Patients With ARDS Treated by HFNO Not Available Not Available unknown_status NCT04401475
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of EB05 + SOC vs. Placebo + SOC in Adult Hospitalized Patients With COVID-19 No drug interventions treatment 2 / 3 recruiting NCT02885675
An Observational Study of the Correlation Between miRNA in Peripheral Blood and Prognosis in Patients With ARDS No drug interventions Not Available Not Available unknown_status NCT04402970
Dornase Alfa for ARDS in Patients With Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) treatment 3 completed NCT04973670
Protective Effect of Sivelestat Sodium on ARDS in Patients With Sepsis No drug interventions prevention 3 recruiting NCT04209270
Breathing Pattern, WOB and Gas Exchange in Patients With Acute Respiratory Distress Syndrome During the Spontaneous Breathing Trial No drug interventions Not Available Not Available unknown_status NCT03793842
Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome No drug interventions treatment Not Available completed NCT04618042
FX06 to Rescue Acute Respiratory Distress Syndrome During Covid-19 Pneumonia No drug interventions treatment 2 completed NCT03546699
Hospital-wide Incidence, Clinical Characteristics and Outcomes of ARDS No drug interventions Not Available Not Available active_not_recruiting NCT06513299
Effectiveness of Low Volume and Low Pressure in Severe Hypoxemic Patients No drug interventions Not Available Not Available active_not_recruiting NCT05104606
Speckle Tracking and Inhaled Nitric Oxide in Acute Respiratory Distress Syndrome No drug interventions diagnostic Not Available recruiting NCT03217149
Heliox for Neonate With Acute Respiratory Distress Syndrome (ARDS) treatment Not Available unknown_status NCT04499313
Dexamethasone Vs Methylprednisolone for the Treatment of Patients With ARDS Caused by COVID-19 treatment 3 unknown_status NCT04014218
Effect of Inhalation Sedation Compared With Propofol on the Sepsis-related Acute Respiratory Distress Syndrome Course No drug interventions treatment 4 unknown_status NCT05710419
Effects of Invasive Mechanical Ventilation on the Right Ventricular Function No drug interventions Not Available Not Available recruiting NCT04657458
Expanded Access for Use of bmMSC-Derived Extracellular Vesicles in Patients With COVID-19 Associated ARDS No drug interventions Not Available Not Available available NCT04410263
Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches No drug interventions Not Available Not Available unknown_status NCT01669863
Extracorporeal Membrane Oxygenation (ECMO) in Non-intubated Patients With Acute Respiratory Distress Syndrome (ARDS) No drug interventions treatment 1 / 2 completed NCT02871063
Effect of Altitude on the Evolution of Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT04737486
A First-in-Human Study of AV-001 in Healthy Subjects No drug interventions treatment 1 completed NCT04494386
Umbilical Cord Lining Stem Cells (ULSC) in Patients With COVID-19 ARDS No drug interventions treatment 1 / 2 completed NCT05493839
A Reverification of the Berlin Definition Plateau Criteria in Golmud No drug interventions Not Available Not Available unknown_status NCT04067622
Novel Arm Restraint For Critically Ill Patients To Reduce Immobility, Sedation, Agitation and Cognitive Impairment No drug interventions treatment Not Available completed NCT03963622
Careful Ventilation in Acute Respiratory Distress Syndrome (COVID-19 and Non-COVID-19) No drug interventions treatment Not Available recruiting NCT05353725
Extracorporeal Membrane Oxygenation in Coronavirus Disease (COVID-19), Influenza and ARDS of Other Ethiologies No drug interventions Not Available Not Available completed NCT04614025
Open-label Multicenter Study to Evaluate the Efficacy of PLX-PAD for the Treatment of COVID-19 treatment 2 terminated NCT05473130
Breethe Abiomed Recovery RegisTry (BART) No drug interventions Not Available Not Available completed NCT02958748
Change of Immune Cell of ARDS Patients：an Observational Study No drug interventions Not Available Not Available unknown_status NCT06072248
Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation treatment 1 / 2 completed NCT05023226
Effectiveness of Recruitment Maneuvers and Lung Protective Ventilation Strategy in ARDS No drug interventions supportive_care Not Available recruiting NCT04525820
High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized Controlled, Multi Center Study treatment Not Available completed NCT05647382
Soluble VE-cadherin in Prediction and Diagnosis of Early Postoperative Hypoxemia After Cardiopulmonary Bypass No drug interventions diagnostic Not Available completed NCT01272882
Electrical Impedance Tomography (EIT) Monitoring in Adults With ALI or ARDS No drug interventions basic_science Not Available completed NCT01902082
Adipose-derived Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome No drug interventions treatment 1 unknown_status NCT04405973
Clinical Scores for Outcome Prediction in Patients With Severe COVID-19 Pneumonia Requiring ECMO No drug interventions Not Available Not Available completed NCT04415073
A Phase 2 Study to Evaluate Axatilimab for Hospitalized Participants With Respiratory Involvement Secondary to COVID-19 treatment 2 terminated NCT04710173
Establishment of a Early Risk Model of ECMO in Children With ARDS No drug interventions Not Available Not Available completed NCT06157073
Efficacy and Safety of Automated Closed-loop Ventilator vs Conventional Open-loop Ventilator in the Emergency Department No drug interventions supportive_care Not Available not_yet_recruiting NCT05874973
Effects of TCAV and Volume Control Ventilation on the Distribution of Aerated Lung Parenchyma in ARDS Patients No drug interventions treatment Not Available recruiting NCT04725227
Determine the Effect of Prone Positioning in Adults With ARDS by Electrical Impedance Tomography No drug interventions Not Available Not Available unknown_status NCT04503876
Effects of End-expiratory Positive Pressure Optimization in Intubated Patients With Healthy Lung or Acute Respiratory Distress Syndrome No drug interventions treatment Not Available unknown_status NCT04360876
Targeted Steroids for ARDS Due to COVID-19 Pneumonia: A Pilot Randomized Clinical Trial treatment 2 withdrawn NCT02595060
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Inhalation to Improve Host Defense and Pulmonary Barrier Restoration treatment 2 completed NCT04411160
Vitamin C Versus Nitric Oxide in Prolonged Ventilation Not Available Not Available completed NCT04402060
A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 treatment 1 / 2 completed NCT03211494
Does Automated Closed-Loop Ventilation Reduce the DRiving Pressure Levels in Patients With ARDS No drug interventions prevention Not Available terminated NCT05101694
Study on the Correlation Between Alveolar Macrophage-derived Autophagosomes and the Severity of Lung Injury in ARDS No drug interventions Not Available Not Available unknown_status NCT00808691
Microcirculation and Oxidative Stress in Critical Ill Patients in Surgical Intensive Care Unit No drug interventions Not Available Not Available completed NCT04643691
Losartan and Spironolactone Treatment for ICU Patients With COVID-19 Suffering From ARDS treatment 2 terminated NCT03217162
Surfactant for Neonate With Acute Respiratory Distress Syndrome (ARDS) No drug interventions treatment Not Available recruiting NCT04327180
PREdiction of DIagnosed Covid-19 infecTion in IUC Patients No drug interventions Not Available Not Available completed NCT05993780
An Evaluation of End-Expiratory Lung Volume and Pulmonary Mechanics With Different PEEP Levels in Mechanical Ventilation in ARDS Patients No drug interventions treatment Not Available completed NCT03371680
Kinetics of Surfactant Proteins, Phosphatidylcholine and Body Water in Intensive Care Unit (ICU) basic_science Not Available completed NCT04371029
Impact of Neck Inspiratory Muscle Activation During Sleep in ICU Patients After a COVID 19 ARDS No drug interventions other Not Available completed NCT04832789
Ultra-Low Tidal Volume Mechanical Ventilation in ARDS Through ECMO No drug interventions treatment Not Available unknown_status NCT02149589
Lung Imaging for Ventilatory Setting in ARDS No drug interventions other Not Available completed NCT05035589
The Effect of Tocilizumab on Procalcitonin and Other Biochemical and Clinical Markers in the Setting of COVID-19 Pneumonia Not Available Not Available completed NCT04941092
Comparison of ARDS COVID-19 (WHO) vs ARDS Influenza in the ICU No drug interventions Not Available Not Available completed NCT04395144
COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss No drug interventions treatment Not Available completed NCT04734340
The Study of EIT-guided Ventilation Strategy on ARDS Patients No drug interventions treatment Not Available unknown_status NCT02361840
Predictive Value of Troponin I for Acute Respiratory Distress Syndrome in Children With Shock No drug interventions Not Available Not Available unknown_status NCT05012267
Duration of Prone Position in the Severe Acute Respiratory Syndrome Coronavirus 2 (COVID-19). No drug interventions treatment Not Available completed NCT04328467
Pre-exposure Prophylaxis for SARS-Coronavirus-2 treatment 3 completed NCT06292767
Cardiopulmonary Bypass on Mechanical Power and Postoperative Pulmonary Complications No drug interventions Not Available Not Available not_yet_recruiting NCT05497401
A Controlled Study to Evaluate the Efficacy of Allogeneic MesenCure for the Treatment of Patients With ARDS No drug interventions treatment 3 not_yet_recruiting NCT01949272
Optimization of PEEP for Alveolar Recruitment in ARDS No drug interventions Not Available Not Available completed NCT06408272
Eit in ArdS for Tcav Setting (EAST Study) No drug interventions Not Available Not Available not_yet_recruiting NCT00143468
The Specific Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients No drug interventions treatment Not Available completed NCT06109168
Correlation of SpO2/FIO2 Ratio With PaO2/FIO2 Ratio in ARDS Patients in the ICU of H. Adam Malik Hospital No drug interventions Not Available Not Available completed NCT04487769
Lung Ultrasound in COVID-19 Patients No drug interventions Not Available Not Available completed NCT06035146
Mechanical Ventilation in Patients With Lung Impairment Controlled by the Mechanical Energy of the Respiratory System No drug interventions treatment Not Available recruiting NCT02703012
Clinical Application of Electrical Impedance Tomography for Individual Adjustment of Ventilator Settings No drug interventions treatment Not Available completed NCT01793012
Drug Monitoring of Antibiotics in Critical Care Patients No drug interventions Not Available Not Available completed NCT04068012
Clinical Decision Support Tool in PARDS Pilot Study No drug interventions prevention Not Available recruiting NCT05414110
Effect of Airway Pressure Release Ventilation on Right Ventricular Function Assessed by Transthoracic Echocardiography No drug interventions Not Available Not Available unknown_status NCT05020210
Effect of Early Treatment With Sivelestat Sodium in ARDS Patients No drug interventions Not Available Not Available unknown_status NCT02174081
ARDS Prediction Score in Critically Ill Patients in China No drug interventions Not Available Not Available completed NCT06400095
Ventilatory Parameters in Predicting Outcomes in ARDS Patients No drug interventions Not Available Not Available recruiting NCT04663555
Effect of Two Different Doses of Dexamethasone in Patients With ARDS and COVID-19 treatment 4 completed NCT02902055
Paediatric Ards Neuromuscular Blockade Study No drug interventions treatment 4 suspended NCT04219150
Cardiometry Versus Fluid and Catheter Treatment Trial (FACTT Lite) on Fluid Management in Acute Respiratory Distress Syndrome Patients No drug interventions treatment Not Available completed NCT00299650
Systematic Early Use of Neuromuscular Blocking Agents in ARDS Patients treatment 4 completed NCT04389450
Double-Blind, Multicenter, Study to Evaluate the Efficacy of PLX PAD for the Treatment of COVID-19 treatment 2 terminated NCT03949738
Cerebrovascular Hemodynamics in Patients With ARDS. No drug interventions Not Available Not Available completed NCT04694638
Use of Combined Prone Positioning and High-Flow Nasal Cannula, and Non-invasive Positive Pressure Ventilation to Prevent Intubation in COVID-19 Infection No drug interventions supportive_care Not Available completed NCT02415738
Changes in Cerebral Oxygenation During the Prone Position in Patients With Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT01683669
Effect of Variable PSV in Acute Lung Injury: Part I and Part II No drug interventions treatment Not Available completed NCT01470703
Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome No drug interventions treatment Not Available completed NCT02425579
Safety Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS) treatment 1 completed NCT06322758
Driving Pressure-guided Tidal Volume Ventilation in the Acute Respiratory Distress Syndrome No drug interventions treatment Not Available not_yet_recruiting NCT01339533
Airway Pressure Release Ventilation (APRV) Versus AC/VC Conventional Ventilation No drug interventions treatment 2 unknown_status NCT03909854
Pragmatic Investigation of Volume Targeted Ventilation-1 No drug interventions treatment Not Available completed NCT01926093
Low Dose Lung CT Scan for Quantitative Analysis in ARDS Patients No drug interventions Not Available Not Available completed NCT02842788
Prevalence of Prone Positioning Use in ARDS Patients No drug interventions Not Available Not Available completed NCT03870009
Validation of a Semi-automatized Method to Detect Cyclic Hyperinflation on CT-scan in ARDS No drug interventions diagnostic Not Available completed NCT05024500
Clinical and Functional Outcomes of Critically Ill Patients With COVID-19 No drug interventions treatment Not Available completed NCT06272942
An Observational Study to Identify New Health Problems Arising After an Intensive Care Unit Admission in People With Acute Respiratory Distress Syndrome in the United States No drug interventions Not Available Not Available active_not_recruiting NCT06002841
Extracellular Vesicles From Mesenchymal Cells in the Treatment of Acute Respiratory Failure No drug interventions treatment 1 / 2 not_yet_recruiting NCT05847517
Metoprolol in Acute Respiratory Distress Syndrome (MAIDEN) treatment 3 not_yet_recruiting NCT04009330
Clinical Evaluation of a Point of Care (POC) Assay to Identify Phenotypes in the Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available active_not_recruiting NCT04609865
Impact of Intravenous Lidocaine on Clinical Outcomes of Patients With ARDS During COVID-19 Pandemia treatment 3 terminated NCT02574169
Alveolar Recruitment Maneuvers, Intracerebral Hemodynamic and Oxygenation No drug interventions treatment Not Available recruiting NCT06127381
An Open-label Study of the Safety and Pharmacokinetics of the TGKP treatment 1 not_yet_recruiting NCT01423864
Intrapleural Methylprednisolone Injection for Multiple Organ Failure With Acute Respiratory Distress Syndrome treatment 2 completed NCT01783821
LIPS-B: Lung Injury Prevention Study With Budesonide and Beta prevention 2 completed NCT01763853
Impact of Fluid Resuscitation Therapy on Pulmonary Edema as Measured by Alveolar Fluid Clearance in Patients With Acute Respiratory Distress Syndrome (ARDS) treatment 4 unknown_status NCT02167698
Trial of an Alternate Mode of Providing Artificial Breaths to Children With Very Severe Pneumonia treatment Not Available terminated NCT02081105
Validation of Digital Chest-X-ray (CXR) to Assess Lung Recruitment in ARDS No drug interventions diagnostic Not Available terminated NCT04311697
Intravenous Aviptadil for Critical COVID-19 With Respiratory Failure treatment 2 / 3 completed NCT01714583
The Relationship Between Positive End Expiratory Pressure and Cardiac Index in Patients With Acute Respiratory Distress Syndrome (ARDS) Managed on a Fluid Protocol No drug interventions Not Available Not Available completed NCT05075161
Pirfenidone to Prevent Fibrosis in Ards. treatment 3 recruiting NCT02637011
Surviving ARDS: The Influence of Quality of Care and Individual Patient Characteristics on Quality of Life No drug interventions Not Available Not Available unknown_status NCT01878552
Energy Load in Patients With Acute Respiratory Distress Syndrome (ARDS) No drug interventions Not Available Not Available completed NCT03296059
Transfusion of Red Blood Cells for Acute Respiratory Distress Syndrome(ARDS) in Neonates No drug interventions treatment Not Available recruiting NCT04460859
RecruitmEnt Assessed by eleCtRical Impedance Tomography No drug interventions Not Available Not Available unknown_status NCT02288949
Stratification of the Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT05938036
Study of Safety and Efficacy of ALT-100mAb in Participants With Moderate/Severe ARDS No drug interventions treatment 2 recruiting NCT04321616
The Efficacy of Different Anti-viral Drugs in COVID 19 Infected Patients treatment 2 / 3 unknown_status NCT04546919
Effect of R-spondin3 on Sepsis Induced Endothelial Dysfunction No drug interventions Not Available Not Available unknown_status NCT01854424
Validation of the Percentage of Alveolar Fibrocyte as Biomarker During ARDS No drug interventions Not Available Not Available completed NCT04548739
Cerebral Autoregulation in Pediatric ECMO (ECMOX 2) No drug interventions Not Available Not Available completed NCT01274260
Trial of Steroids in Pediatric Acute Lung Injury/ARDS treatment 2 unknown_status NCT01906229
Lung and Systemic Inflammation in the Critically Ill Patient No drug interventions Not Available Not Available terminated NCT02095444
Using Human Menstrual Blood Cells to Treat Acute Lung Injury Caused by H7N9 Bird Flu Virus Infection No drug interventions treatment 1 / 2 unknown_status NCT01506401
The Oscillation for Acute Respiratory Distress Syndrome (ARDS) Treated Early (OSCILLATE) Trial No drug interventions treatment 3 terminated NCT02058004
Does Cricoid Pressure Reduce the Risk of Aspiration? No drug interventions prevention Not Available completed NCT04511650
Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019 treatment 2 terminated NCT04247477
Comparison of Different PEEP Titration Strategies Using Electrical Impedance Tomography in Patients With ARDS No drug interventions treatment Not Available completed NCT05933291
Single-cell Landscape of BALF in Patients With Severe ARDS and CARDS No drug interventions Not Available Not Available completed NCT06117761
Combined Activity and Cognitive Intervention for ICU Survivors No drug interventions prevention Not Available enrolling_by_invitation NCT01670747
Evaluation of the Lung Recruitment and End-expiratory Lung Collapse in Acute Respiratory Distress Syndrome (ARDS) No drug interventions Not Available Not Available completed NCT02859194
The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary Oxygenation in Lung Transplantation Patients No drug interventions treatment Not Available completed NCT01913977
Clinical Study to Determine the Optimal Operation Parameters During CO2 Removal With the Abylcap® System No drug interventions treatment Not Available completed NCT03827863
Acute CorPulmonale and ARDS Circulation Protection China Study China (ACPC) No drug interventions Not Available Not Available unknown_status NCT00796419
Comparative Evaluation of Albumin and Starch Effects in Acute Lung Injury (ALI) treatment 3 terminated NCT02944279
Neutrophil Elastase and Elafin as Prognostic Biomarker for Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT04693403
Adult Respiratory Failure Intervention Study Africa No drug interventions treatment Not Available completed NCT04337190
Impact of Angiotensin II Receptor Blockers Treatment in Patients With COVID 19 (COVID-ARA2) No drug interventions Not Available Not Available unknown_status NCT06184490
Prone Position With Different Types of Cushions in Patients With ARDS No drug interventions supportive_care Not Available recruiting NCT00759590
Comparison of Two Methods to Estimate the Lung Recruitment No drug interventions Not Available Not Available unknown_status NCT04286490
Prone Position and Renal Resistive Index No drug interventions other Not Available unknown_status NCT02639364
Airway Pressure Release Ventilation (APRV) Protocol Early Used in Acute Respiratory Distress Syndrome No drug interventions treatment Not Available unknown_status NCT00288964
Use of the Hattler Respiratory Assist Catheter in Severe Respiratory Failure No drug interventions Not Available 3 withdrawn NCT02625064
Discovery of New Early Detection Biomarkers of Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available unknown_status NCT04355364
Efficacy and Safety of aerosolizedDornase Alfa Administration in Patients With COVID19 Induced ARDS (COVIDORNASE) treatment 3 terminated NCT04760821
Prevention of Acute Myocardial Injury by Trimetazidine in Patients Hospitalized for COVID-19 treatment 2 unknown_status NCT04552821
Study of Biomarkers in Patients of Sepsis Complicated With Acute Respiratory Distress Syndrome (ARDS) No drug interventions Not Available Not Available unknown_status NCT00284102
PEEP Test and Gas Exchange in ALI/ARDS Patients No drug interventions treatment Not Available completed NCT06226402
Effect of Nebulized and Intravenous Hypertonic Saline 3% on the Management of Patients With Acute Respiratory Distress Syndrome No drug interventions treatment Not Available recruiting NCT03642002
The Effects of Music Therapy on Adult Patients Requiring Mechanical Ventilation in the ICU No drug interventions supportive_care Not Available recruiting NCT01478802
High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS) No drug interventions treatment 2 / 3 terminated NCT06066502
Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome No drug interventions treatment 3 recruiting NCT00830284
Efficacy and Safety of a Lung Recruitment Protocol in Children With Acute Lung Injury No drug interventions treatment Not Available completed NCT04078984
Driving Pressure as a Predictor of Mechanical Ventilation Weaning Time on Post-ARDS Patients in Pressure Support Ventilation. No drug interventions Not Available Not Available completed NCT00431379
Treatment of Acute Respiratory Distress Syndrome With Tenecteplase: A Dose Escalation Pilot Study treatment 1 withdrawn NCT06213779
The Burden of Acute Respiratory Failure in Chinese ICUs: a National Cohort Study No drug interventions Not Available Not Available recruiting NCT05849779
Inhaled Sevoflurane for ARDS Prevention treatment 3 recruiting NCT04804943
Pilot Clinical Study of NOA-001 for ARDS (Acute Respiratory Distress Syndrome) No drug interventions treatment Not Available recruiting NCT01093287
Predictors for Responsiveness to Corticosteroid in Patients With Early Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available terminated NCT02155387
Extravascular Lung Water and Pulmonary Vascular Permeability After Minimally Invasive Cardiac Surgery No drug interventions Not Available Not Available unknown_status NCT01911533
Veno-venous Extracorporeal CO2 Removal in ARDS-patients to Treat Respiratory Acidosis No drug interventions treatment Not Available completed NCT06249633
Inhaled Nitric Oxide for ARDS-related Pulmonary Hypertension treatment 0 not_yet_recruiting NCT05816954
Imaging Biomarkers to Stratify the Risk of Barotrauma in ARDS No drug interventions Not Available Not Available recruiting NCT05365854
Hemodynamic Effects of Two Modalities of Alveolar Recruitment Maneuvers - ICU Patients No drug interventions diagnostic Not Available unknown_status NCT04754854
Reduction of Blood Recirculation in Veno-Venous ECMO No drug interventions Not Available Not Available recruiting NCT04359251
Different PEEP Settings of COVID-19 Induced ARDS No drug interventions treatment Not Available completed NCT01600651
Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study) No drug interventions treatment 4 completed NCT03715751
Adaptive Support Ventilation in Acute Respiratory Distress Syndrome No drug interventions basic_science Not Available completed NCT04070053
Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning (TheraPPP) Pathway No drug interventions treatment Not Available completed NCT04853953
Cerebral Bleeding in COVID-19 ARDS Patients on Veno-venous ECMO No drug interventions Not Available Not Available unknown_status NCT05611177
Predicting ICU Mortality in ARDS Patients No drug interventions Not Available Not Available completed NCT04311177
Losartan for Patients With COVID-19 Not Requiring Hospitalization treatment 2 completed NCT02047877
Airway Inflammatory Response During Illness in Children With Respiratory Failure No drug interventions Not Available Not Available withdrawn NCT05464277
Intermediate Normal Versus High Normal Oxygen Levels in the Emergency Department for Severe Traumatic Brain Injury No drug interventions treatment Not Available terminated NCT02546947
Monitoring in Intensive Care Unit of Neuromuscular Blocking Agents Used for Acute Respiratory Distress Syndrome After Cardiothoracic Surgery No drug interventions other Not Available completed NCT03017547
A Phase 2 Study of IC14 in Acute Respiratory Distress Syndrome No drug interventions treatment 2 withdrawn NCT06001645
Laboratory Biomarkers and Pulmonary Interstitial Emphysema in ARDS (PIE-ARDS) No drug interventions Not Available Not Available recruiting NCT04384445
Zofin (Organicell Flow) for Patients With COVID-19 treatment 1 / 2 completed NCT05026645
The Medical Management in Patients Exposed to Weapons of Mass Destruction No drug interventions Not Available Not Available enrolling_by_invitation NCT04466098
Multiple Dosing of Mesenchymal Stromal Cells in Patients With ARDS (COVID-19) treatment 2 active_not_recruiting NCT01131598
Acute Lung Injury in Children: Epidemiology and Natural History. PEDIATRIC ALIEN. No drug interventions Not Available Not Available unknown_status NCT04369105
Prono Position and Mechanical Power No drug interventions Not Available Not Available completed NCT04457505
One Year Follow-ups of Patients Admitted to Spanish Intensive Care Units Due to COVID-19 No drug interventions Not Available Not Available completed NCT04376905
Extra Vascular Lung Water and Pulmonary Permeability in Critically Ill Patients With SARS-CoV-2 (COVID-19) No drug interventions Not Available Not Available completed NCT04909697
Treatment of ARDS With Sivelestat Sodium No drug interventions treatment 4 unknown_status NCT06496997
A Comparative Study of Glucocorticoids Efficacy in Acute Respiratory Distress Syndrome treatment 2 / 3 not_yet_recruiting NCT04337983
Hemodynamic Characteristics of Patients With SARS-CoV-2 No drug interventions Not Available Not Available completed NCT05150483
EndotyPIng PreHospitAl de Novo Acute hYpoxemic Respiratory Failure No drug interventions Not Available Not Available recruiting NCT06477861
The Role of Elastic Power in Predicting the Severity and Mortality in Adult Patients With ARDS Due to Pneumonia No drug interventions Not Available Not Available recruiting NCT01504893
Very Low Tidal Volume vs Conventional Ventilatory Strategy for One-lung Ventilation in Thoracic Anesthesia No drug interventions prevention Not Available completed NCT03844893
Macrophage Programing in Acute Lung Injury No drug interventions Not Available Not Available unknown_status NCT05000671
A Study to Evaluate the Safety and Effect of STC314 Injection Continuous Infusion in Subjects With Acute Respiratory Distress Syndrome No drug interventions treatment 1 unknown_status NCT05767671
Macrophage Programing in Acute Lung Injury: MiniBAL No drug interventions basic_science Not Available recruiting NCT00813371
Airway Pressure Release Ventilation as a Preventative Strategy No drug interventions prevention Not Available withdrawn NCT04478071
Vadadustat for the Prevention and Treatment of Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) treatment 2 completed NCT04453371
Impact of Tissue Plasminogen Activator (tPA) Treatment for an Atypical Acute Respiratory Distress Syndrome (COVID-19) treatment 3 withdrawn NCT04383678
Outcome of COVID-19 Patients After Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT04475588
Efficacy and Safety of Itolizumab in COVID-19 Complications treatment 2 completed NCT04973488
Therapeutic Plasma Exchange Followed by Convalescent Plasma Transfusion in Severe and Critically Ill COVID-19 Patients No drug interventions treatment Not Available completed NCT04154007
Acute Kidney Injury in Patients With Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT06215209
Effect of PP in Patients With Ultra-low VT No drug interventions Not Available Not Available recruiting NCT03179709
Provider Perceptions of Neuromuscular Blockade in ARDS No drug interventions Not Available Not Available completed NCT05079009
Effects of Blood Pulsatility on Von Willebrand Factor During ECCO2R No drug interventions treatment Not Available completed NCT04815109
Prospective Electroencephalography Evaluation of Sedation in COVID-19 No drug interventions Not Available Not Available completed NCT01114009
Effects of Recruitment Maneuvers in Early Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS) Patients No drug interventions treatment Not Available completed NCT02611609
A Phase 1/2 Study to Assess MultiStem® Therapy in Acute Respiratory Distress Syndrome treatment 1 / 2 completed NCT00474656
The Oscillation for ARDS Treated Early (OSCILLATE) Trial Pilot Study No drug interventions treatment Not Available completed NCT04475185
Safety and Effectiveness Assessment of the MakAir Artificial Ventilator No drug interventions supportive_care Not Available terminated NCT02881385
Effects on Respiratory Patterns and Patient-ventilator Synchrony Using Pressure Support Ventilation No drug interventions Not Available Not Available unknown_status NCT05611385
Amphetamine Induced Adult Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT02416037
Trans-pulmonary Pressure in ARDS No drug interventions treatment Not Available completed NCT04221737
Early Use of Airway Pressure Release Ventilation (APRV) in ARDS No drug interventions treatment Not Available recruiting NCT01335932
Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure prevention 2 completed NCT04400032
Cellular Immuno-Therapy for COVID-19 Acute Respiratory Distress Syndrome treatment 1 / 2 completed NCT05238532
Clinical Trial to Evaluate the Safety, Tolerability and Efficacy of CT303 in Patients With ARDS No drug interventions treatment 1 withdrawn NCT05629832
Transpulmonary Pressure in Right Ventricle Protection of ARDS No drug interventions prevention Not Available recruiting NCT00659152
Morphofunctional Lung Analysis by Positron Emission Tomography No drug interventions Not Available Not Available completed NCT02550600
Extracorporeal Lung Assist Device in Acute Lung Impairment No drug interventions treatment Not Available unknown_status NCT02247700
Observational Cohort Study of Distribution of Ventilation in Pediatrics Requiring Mechanical Ventilation by Electrical Impedance Tomography No drug interventions Not Available Not Available completed NCT01089400
Immuno-virological Characterization of Severe H1N1v Influenza Infection in Bronchoalveolar Lavage No drug interventions Not Available Not Available completed NCT00568659
The Specific Lung Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients in Supine and Prone Position No drug interventions treatment Not Available completed NCT06278675
Multiple Study of Electroaccpuncture in ARDS No drug interventions treatment Not Available not_yet_recruiting NCT03984175
Clinical Decision Support for Mechanical Ventilation of Patients With ARDS No drug interventions health_services_research Not Available unknown_status NCT03031275
Long-term Follow Up of Adult Patients Treated With Extracorporeal Membrane Oxygenation for Respiratory Failure No drug interventions other Not Available completed NCT01552070
Recruitment on Extravascular Lung Water in Acute Respiratory Distress Syndrome (ARDS) No drug interventions diagnostic 2 completed NCT05158842
Treatment of COVID-19 Positive/Negative Bangladeshi Adults With Severe Respiratory Complaints by a Locally Made bCPAP: Feasibility Study No drug interventions device_feasibility Not Available completed NCT01050699
Sleep Intervention During Acute Lung Injury treatment 4 completed NCT04369599
Trans Thoracic Manipulation of Ventilation/Perfusion: the V/Q System No drug interventions treatment Not Available enrolling_by_invitation NCT04537806
A Study of Brexanolone for Acute Respiratory Distress Syndrome (ARDS) Due to Coronavirus Disease 2019 (COVID-19) treatment 3 terminated NCT04325906
Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS No drug interventions treatment Not Available completed NCT00879606
Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome No drug interventions treatment 2 completed NCT03038906
Effect of Randomization to Neuromuscular Blockade on Physical Functional Impairment and Recovery in ARDS No drug interventions Not Available Not Available unknown_status NCT03462849
Expiratory Flow Limitation Assessment No drug interventions diagnostic Not Available completed NCT04417036
This Study Collects Information on the Safety of Inhaled Pegylated Adrenomedullin (PEG-ADM), How the Drug is Tolerated and How it Affects Patients Suffering From a Type of Lung Failure That Cause Fluid to Build up in the Lungs Making Breathing Difficult (ARDS) No drug interventions treatment 2 terminated NCT05146336
CytOSorb TreatMent Of Critically Ill PatientS Registry No drug interventions Not Available Not Available recruiting NCT06254313
The Role of Cxcr4Hi neutrOPhils in InflueNza No drug interventions Not Available Not Available not_yet_recruiting NCT04331613
Safety and Efficacy of CAStem for Severe COVID-19 Associated With/Without ARDS treatment 1 / 2 unknown_status NCT05930418
Cardiovascular Magnetic Resonance Prognosticators in Pediatric Oncology Patients With Sepsis No drug interventions diagnostic Not Available recruiting NCT04925518
Closed Loop Mechanical Ventilation and ECMO No drug interventions treatment Not Available completed NCT02232841
Electrical Impedance Imaging of Patients on Mechanical Ventilation No drug interventions Not Available Not Available completed NCT06505941
Clinical Study on the Safety and Preliminary Efficacy of hUC-MSCs Intravenous Infusion Therapy for ARDS No drug interventions treatment 1 / 2 not_yet_recruiting NCT02457741
Validation of a Simple Approach to Estimate Alveolar Recruitability in ARDS Patients No drug interventions Not Available Not Available completed NCT05825534
Pressure Opening With Electrical Impedance Tomography No drug interventions other Not Available recruiting NCT03021824
Severe ARDS: Generating Evidence No drug interventions Not Available Not Available completed NCT01862016
Early Spontaneous Breathing in Acute Respiratory Distress Syndrome No drug interventions treatment Not Available unknown_status NCT01048996
Genetic Variability and Biomarkers in Children With Acute Lung Injury No drug interventions Not Available Not Available withdrawn NCT05675696
Assessment of Occult Lung Stress During Lung Protective Mechanical Ventilation No drug interventions other Not Available not_yet_recruiting NCT00006496
Molecular Epidemiology of ARDS No drug interventions Not Available Not Available unknown_status NCT06061796
Physiological Study of Prone Position in Acute Respiratory Failure Syndrome No drug interventions treatment Not Available recruiting NCT04133558
Pulmonary Microbiota and ARDS Mortality No drug interventions Not Available Not Available unknown_status NCT02963558
A Study Promoting Critical Illness Recovery in the Elderly No drug interventions treatment Not Available completed NCT02113735
Safety and Efficacy Study of Acthar in Subjects With ARDS treatment 2 withdrawn NCT04380935
Effectiveness and Safety of Convalescent Plasma Therapy on COVID-19 Patients With Acute Respiratory Distress Syndrome No drug interventions treatment 2 / 3 unknown_status NCT05640635
Inflammation During ECMO Therapy and ECMO Weaning No drug interventions treatment Not Available recruiting NCT03201263
Sigh in Acute Hypoxemic Respiratory Failure No drug interventions treatment Not Available completed NCT04490486
Umbilical Cord Tissue (UC) Derived Mesenchymal Stem Cells (MSCs) Versus Placebo to Treat Acute Pulmonary Inflammation Due to COVID-19 treatment 1 withdrawn NCT05042622
Organ-substituting Technologies in the Treatment of Heart and Pulmonary Failure No drug interventions treatment Not Available unknown_status NCT01102322
Factors Associated With the Use of Lung Protective Ventilation Strategy (LPV) in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients in Intensive Care Unit (ICU) No drug interventions Not Available Not Available completed NCT02450825
Comparison of Three Scores for Ultrasound Assessment and Monitoring of Pulmonary Aeration No drug interventions diagnostic Not Available completed NCT01681225
EPVent 2- A Phase II Study of Mechanical Ventilation Directed by Transpulmonary Pressures No drug interventions treatment Not Available completed NCT06006325
Electroacupuncture Modulates SPMs Metabolism and Respiratory Symptoms in Patients With Sepsis Complicating ARDS No drug interventions treatment Not Available recruiting NCT01003730
The Effects of Different Ventilator Strategies on Inflammation and Injury in Normal Lungs No drug interventions treatment Not Available terminated NCT05768230
Using TEE to Evaluate the Effect of Levosimendan on Patients With ARDS Associated With RVD During MV treatment 2 / 3 not_yet_recruiting NCT00644930
Non-Invasive Positive Pressure Ventilation and Adult Respiratory Distress Syndrome (ARDS) No drug interventions treatment Not Available completed NCT03828630
Lung Ultrasound to Detect Pulmonary Complications in Critically Ill Parturients No drug interventions Not Available Not Available completed NCT01677130
Standardized Application of High Frequency Oscillatory Ventilation in the Acute Respiratory Distress Syndrome (ARDS) No drug interventions Not Available Not Available completed NCT00559130
Efficacy Study of CytoSorb Hemoperfusion Device on IL-6 Removal in ARDS/ALI Patients With Sepsis No drug interventions treatment Not Available completed NCT03260348
Acute Respiratory Distress Syndrome in Taiwan No drug interventions Not Available Not Available unknown_status NCT05650957
PRactice of VENTilation in Patients With ARDS Due to COVID-19 vs Pneumonia No drug interventions Not Available Not Available completed NCT04305457
Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID-19 treatment 2 active_not_recruiting NCT03089957
Prevention of Ulinastatin on Acute Respiratory Distress Syndrome (ARDS) prevention Not Available completed NCT05761626
Mechanical Power and Ventilatory Ratio in ARDS No drug interventions Not Available Not Available completed NCT04408326
Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome Not Available Not Available unknown_status NCT05754866
Transbronchial Lung Cryobiopsy in Undiagnosed Acute Respiratory Failure No drug interventions diagnostic Not Available recruiting NCT05566665
Nosocomial Infections in ECMO Patients No drug interventions Not Available Not Available recruiting NCT02601365
Inhaled GM-CSF for Respiratory Virus-Associated Severe Pneumonia treatment 1 withdrawn NCT04319965
Complications Related to Transpulmonary Thermodilution No drug interventions Not Available Not Available unknown_status NCT01186874
Epidemiology Research on Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) in Adult ICU in Shanghai No drug interventions Not Available Not Available unknown_status NCT05537974
Open Suction vs. Closed Suction in ARDS No drug interventions screening Not Available completed NCT03799874
Safety and Efficacy Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS) treatment 2 active_not_recruiting NCT02787720
Rehabilitation Techniques on Survivors of Acute Respiratory Distress Syndrome No drug interventions supportive_care Not Available completed NCT03589482
Assessing Lung Inhomogeneity During Ventilation for Acute Hypoxemic Respiratory Failure No drug interventions treatment Not Available completed NCT00742482
Efficacy and Safety of 3 Doses of HL10 Given at Fixed Time Intervals Compared to Standard Therapy No drug interventions treatment 3 terminated NCT01526382
Use of PiCCO System in Critically Ill Patients With Septic Shock and Acute Respiratory Distress Syndrome No drug interventions treatment 1 / 2 completed NCT03281473
Comparison of Positive End Expiratory Pressure Titration Methods in ARDS Patients No drug interventions other Not Available unknown_status NCT03763773
Prediction of Outcomes With a Miniaturized Transesophageal Echocardiography Probe in Patients With Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT02463773
Diaphragm Ultrasound Vs Transpulmonary Pressure To Set PEEP in ARDS No drug interventions diagnostic Not Available completed NCT06206473
Cognitive Dysfunctions Associated With Delirium in Critically-ill ARDS Patients No drug interventions basic_science Not Available not_yet_recruiting NCT05983627
Safety and Tolerance of Umbilical Cord Mesenchymal Stem Cells in Patients With Acute Respiratory Distress Syndrome treatment 1 not_yet_recruiting NCT02214576
High Flow Nasal Canula Oxygen Helps Preoxygenate ARDS Patients No drug interventions Not Available Not Available completed NCT05750576
Impact of ECMO Cannula Chlorhexidine-impregnated Dressings to Decrease Extracorporeal Membrane Oxygenation-cannula Related Infection Rate No drug interventions other Not Available not_yet_recruiting NCT04472260
Early Verticalization of the Patient With Acute Respiratory Distress Syndrome: Assessment of Feasibility and Safety. No drug interventions other Not Available recruiting NCT05765760
Improvement of ARDS Ventilation-perfusion Matching by Prone Positioning Assessed by EIT No drug interventions Not Available Not Available recruiting NCT04640194
A Study to Test Whether Different Doses of Alteplase Help People With Severe Breathing Problems Because of COVID-19 treatment 2 / 3 completed NCT02870894
Electrical Impedance Tomography for Quantification of Pulmonary Edema in Acute Respiratory Distress Syndrome Patients No drug interventions Not Available Not Available unknown_status NCT04289194
Clinical Study to Assess the Safety and Preliminary Efficacy of HCR040 in Acute Respiratory Distress Syndrome treatment 1 / 2 completed NCT05857891
The Effect of Erythropoietin on Alveolar Fluid Clearance in Patients With Acute Respiratory Distress Syndrome treatment Not Available recruiting NCT04524091
Inspiratory Ratio: Predictor of Inspiratory Effort Response to High PEEP in Patients Recovering From ARDS No drug interventions Not Available Not Available recruiting NCT05894291
Comparaison of Two Prone Position Techniques on Occurence of Pressure Sores in ICU No drug interventions prevention Not Available recruiting NCT00981591
Inhaled Iloprost as an Adjunct to Inhaled Nitric Oxide in Pediatric Critical Care Patients treatment 1 / 2 withdrawn NCT02403791
Point-of-Care Bedside Lung Ultrasound Examination Advanced Trial Protocol No drug interventions diagnostic Not Available completed NCT04359862
Sedation With Sevoflurane Versus Propofol in Patients With Acute Respiratory Distress Syndrome Caused by COVID19 Infection treatment 4 terminated NCT04903262
Ultra-Protective Lung Ventilation With Extracorporeal CO2 Removal for Moderate ARDS No drug interventions treatment Not Available not_yet_recruiting NCT05958862
Stability of Driving Pressure Changes During "Best Positive End Expiratory Pressure (PEEP)" Trial No drug interventions Not Available Not Available not_yet_recruiting NCT04836780
DEXamethasone EARLY Administration in Hospitalized Patients With Covid-19 Pneumonia prevention 3 recruiting NCT01619280
Safety Study of Nebulized Sodium Nitroprusside in Adult Acute Lung Injury treatment 1 unknown_status NCT04435080
Physical Rehabilitation in ICU in ARDS Patients With COVID-19 No drug interventions Not Available Not Available completed NCT04615429
Clinical Trial to Assess the Efficacy of MSC in Patients With ARDS Due to COVID-19 treatment 2 unknown_status NCT01435889
Long Term (1 Year) Respiratory Sequelae in Children Surviving an Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT05658692
Platform Adaptive Embedded Trial for Acute Respiratory Distress Syndrome treatment 4 recruiting NCT02623192
Respiratory Mechanics Registry for ARDS Patients No drug interventions Not Available Not Available unknown_status NCT04695392
Restore Resilience in Critically Ill Children No drug interventions supportive_care Not Available completed NCT03608592
Human Umbilical Cord Mesenchymal Stem Cells (MSCs) Therapy in ARDS No drug interventions treatment Not Available unknown_status NCT04378244
CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19 treatment 1 / 2 withdrawn NCT04669444
Biomarkers, Genomics, Physiology in Critically Ill and ECMO Patients No drug interventions basic_science Not Available active_not_recruiting NCT01306240
Surfactant Versus Nasal Continuous Positive Airway Pressure (nCPAP) for Respiratory Distress Syndrome in the Newborn ≥ 35 Weeks of Gestation No drug interventions treatment 3 terminated NCT04402840
Stellate Ganglion Block (SGB) for COVID-19 Acute Respiratory Distress Syndrome (ARDS) No drug interventions treatment Not Available completed NCT04347967
Mesenchymal Stem Cells for The Treatment of Acute Respiratory Distress Syndrome (ARDS) No drug interventions treatment 1 not_yet_recruiting NCT05794867
Ultrasonic Weaning Criteria in Prolonged Ventilation No drug interventions Not Available Not Available completed NCT00234767
Study of the Economics of Pulmonary Artery Catheter Use in Patients With Acute Respiratory Distress Syndrome (ARDS) No drug interventions Not Available Not Available completed NCT01504867
LIPS-A: Lung Injury Prevention Study With Aspirin prevention 2 completed NCT00750204
Airway Pressure Release Ventilation in Acute Lung Injury No drug interventions treatment Not Available terminated NCT04815304
Clinical Features of COVID-19 Patients No drug interventions Not Available Not Available completed NCT04602104
A Clinical Study of Mesenchymal Stem Cell Exosomes Nebulizer for the Treatment of ARDS No drug interventions treatment 1 / 2 completed NCT04696172
Plasma Biomarkers of Cardiopulmonary Bypass Induced Acute Respiratory Distress Syndrome (CPB-ARDS) No drug interventions Not Available Not Available completed NCT05672472
Neutrophil Elastase Inhibitor in Treatment of ARDS Patients With Mechanical Ventilation Caused by Sepsis No drug interventions treatment Not Available not_yet_recruiting NCT04308668
Post-exposure Prophylaxis / Preemptive Therapy for SARS-Coronavirus-2 treatment 3 completed NCT06332768
NIV Versus HFO Versus Standard Therapy Immediately After Weaning From Mechanical Ventilation in ARDS Patients No drug interventions supportive_care Not Available completed NCT01864668
the Influence of Tidal Volume to Lung Strain No drug interventions Not Available Not Available unknown_status NCT04387669
Maneuver for Evaluating the Potential Recruitability of the Pulmonary Parenchyme in Patients With ARDS No drug interventions Not Available Not Available unknown_status NCT04534569
Expert Panel Statement for the Respiratory Management of COVID-19 Related Acute Respiratory Failure (C-ARF) No drug interventions Not Available Not Available completed NCT05822869
Early PP Monitored by EIT in Patients With ARDS No drug interventions treatment Not Available recruiting NCT05898269
Fluid Responsiveness Prediction During Prone Position No drug interventions other Not Available recruiting NCT02201446
The Role of Circulating Soluble CD74 in Acute Lung Injury No drug interventions Not Available Not Available completed NCT04433546
Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS). treatment 2 terminated NCT01667146
Open Lung Ventilation in ARDS: The PHARLAP Trial No drug interventions treatment Not Available terminated NCT06062212
Effect of Transpulmonary MP on Prognosis of Patients With Severe ARDS Treated With VV-ECMO No drug interventions Not Available Not Available recruiting NCT03753412
Recovery From ICUAW Following Severe Respiratory and Cardiac Failure No drug interventions Not Available Not Available recruiting NCT00435110
Effects of PEEP and FIO2 in ALI and ARDS No drug interventions Not Available Not Available completed NCT04350710
Description of Respiratory Mechanics in Patients With SARS-CoV-2 Associated ARDS No drug interventions Not Available Not Available unknown_status NCT03549910
A Multicenter, Random Control Study :Early Use of Airway Pressure Release Ventilation (APRVplus) Protocol in ARDS No drug interventions supportive_care Not Available recruiting NCT03346681
N-Acetyl-cysteine in Early Acute Respiratory Distress Syndrome treatment 0 withdrawn NCT04449081
Knowledge, Attitude and Practice of Dental Students About COVID-19 No drug interventions Not Available Not Available completed NCT01270295
Soluble Forms and Ligands of RAGE in ALI/ARDS (SoLiRAGE). No drug interventions Not Available Not Available completed NCT01731795
Efficacy Study of Dexamethasone to Treat the Acute Respiratory Distress Syndrome treatment 4 completed NCT00557414
Serial Changes of Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) Levels in Patients With Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT05947955
Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS) treatment 2 not_yet_recruiting NCT04937855
The Mechanism of lncRNA NEAT1 in Alleviating Acute Respiratory Distress Syndrome Through miR-27b Regulated Nrf2 Pathway No drug interventions Not Available Not Available unknown_status NCT05123755
Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia. No drug interventions treatment 2 recruiting NCT01581255
The Effect of High Frequency Oscillation on Biological Markers of Lung Injury No drug interventions Not Available Not Available terminated NCT03262155
Study of Immunity Dysfunction Induced by Extracorporeal Assistance (ECMO / ECLS) No drug interventions Not Available Not Available completed NCT02444455
Human Umbilical-Cord-Derived Mesenchymal Stem Cell Therapy in Acute Lung Injury No drug interventions treatment 1 / 2 unknown_status NCT05676723
Thoracic Fluid Content by Bioimpedance-based Starling System No drug interventions Not Available Not Available completed NCT04786808
Risk Factors for COVID-19 Mortality No drug interventions Not Available Not Available terminated NCT04291508
Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery treatment 2 completed NCT05388708
ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND) No drug interventions Not Available Not Available recruiting NCT02184208
Retrospective Review of Mechanically Ventilated Patients Using a Continuous Data Collection System. No drug interventions Not Available Not Available completed NCT04776408
Potential for Inhaled Nitric Oxide and Ventilation-Perfusion Mismatch by Electrical Impedance Tomography in the ARDS Patients With Lung Recruitment No drug interventions treatment Not Available enrolling_by_invitation NCT04235608
SEvoflurane for Sedation in ARds treatment 3 active_not_recruiting NCT02975908
A Realworld Study of Acute Respiratory Distress Syndrome in China No drug interventions Not Available Not Available unknown_status NCT01326208
Strategies to Optimize Positive End-expiratory Pressure (PEEP) in Patients With Acute Lung Injury No drug interventions treatment 2 unknown_status NCT04156438
Airway Pressure Release Ventilation for Moderate-to-severe Acute Respiratory Distress Syndrome No drug interventions treatment Not Available completed NCT06014138
Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome basic_science 2 / 3 recruiting NCT05248243
Recruitment Assessment in Patients With Acute Respiratory Distress Syndrome and Covid-19 No drug interventions Not Available Not Available recruiting NCT06536543
EIT Assessment of Overdistension in ARDS Patients in Prone Position No drug interventions Not Available Not Available not_yet_recruiting NCT04601090
Survival Rates and Longterm Outcomes After COVID-19 No drug interventions Not Available Not Available completed NCT04818164
Prone Position Improves End-Expiratory Lung Volumes in COVID-19 Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT02641964
Risk Factors for ARDS in Patients With Acute Necrotizing Pancreatitis No drug interventions Not Available Not Available completed NCT02545621
A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study No drug interventions Not Available Not Available completed NCT01623921
Statins and Selective Cyclooxygenase-2 Receptor Inhibitors in Blunt Chest Trauma treatment Not Available unknown_status NCT03896802
Hemodynamic Effects of PEEP in ARDS No drug interventions treatment Not Available unknown_status NCT02871102
Stress Index to Individualize Mechanical Ventilation in ARDS No drug interventions diagnostic Not Available terminated NCT04507802
Helmet vs Face Mask in Patients With Acute Respiratory Distress Syndrome No drug interventions treatment Not Available unknown_status NCT00290602
Early Low Dose Steroid Therapy of Acute Respiratory Distress Syndrome treatment 2 completed NCT04064684
Inhaled Steroids for the Treatment of Early Pediatric Acute Respiratory Distress Syndrome treatment 2 terminated NCT05164484
Assessment of Cardiac Output in Patients With ARDS Implanted With Venous-venous ECMO. No drug interventions supportive_care Not Available recruiting NCT04316884
Mechanisms for Organ Dysfunction in Covid-19 No drug interventions Not Available Not Available recruiting NCT05060679
Presepsin:Gelsolin Ratio in Sepsis-related Organ Dysfunction No drug interventions Not Available Not Available completed NCT05844579
The ICU LIBERATION Study No drug interventions Not Available Not Available recruiting NCT04158479
China Extracorporeal Life Support Registry No drug interventions Not Available Not Available recruiting NCT04404387
Lessening Organ Dysfunction With VITamin C in Septic ARDS treatment 3 recruiting NCT00240487
Nitric Oxide Administration for Acute Respiratory Distress Syndrome treatment 3 completed NCT00714987
The EVLW for Set the Positive End Expiratory Pressure (PEEP) in the Acute Respiratory Distress Syndrome (ARDS) No drug interventions Not Available Not Available withdrawn NCT03926533
TelePORT Pilot Study No drug interventions health_services_research Not Available completed NCT04502433
Poractant Alfa (Curosurf®)) -- Effect in Adult Patients Diagnosed With 2019 Novel Coronavirus (SARS-COV-19; (Covid-19)) Acute Respiratory Distress Syndrome (ARDS) treatment 2 terminated NCT01304654
ALI/ARDS in Oncologic Pediatric Patients No drug interventions Not Available Not Available unknown_status NCT05914454
Efficacy and Safety of Anakinra in Acute Respiratory Distress Syndrome treatment 2 recruiting NCT03511651
The Effect of Positive End-Expiratory Pressure on Functional Residual Capacity During Mechanical Ventilation No drug interventions other Not Available unknown_status NCT04537351
The MEseNchymal coviD-19 Trial: MSCs in Adults With Respiratory Failure Due to COVID-19 or Another Underlying Cause treatment 1 completed NCT02713451
Liberal Oxygenation Versus Conservative Oxygenation in ARDS No drug interventions treatment 3 unknown_status NCT00215553
KLâ‚„Surfactant Treatment in Patients With ARDS treatment 2 terminated NCT01438853
Effects of TNX-832 (Sunol cH36) in Subjects With Acute Lung Injury/Acute Respiratory Distress Syndrome No drug interventions treatment 1 completed NCT02166853
Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study) treatment 4 completed NCT02819453
Corticosteroid Treatment for Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT04998253
Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction in ARDS Secondary to SARS-CoV2 treatment 0 completed NCT05993377
Prediction of Duration of Mechanical Ventilation in ARDS No drug interventions Not Available Not Available completed NCT02376647
ART-3 Pilot - Driving Pressure Limited Ventilation for Patients Without ARDS (ART3pilot) No drug interventions treatment Not Available withdrawn NCT05826847
Prone Positioning and Abdominal Binding on Lung and Muscle Protection in ARDS Patients During Spontaneous Breathing No drug interventions supportive_care Not Available recruiting NCT06517745
Effect of Prone Positionning in Non Intubated Patients No drug interventions Not Available Not Available completed NCT04744298
Identification and Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning Pathway No drug interventions treatment Not Available active_not_recruiting NCT02962505
Continuous Regional Analysis Device for Neonate Lung No drug interventions Not Available Not Available completed NCT01373905
Stepwise Positive End Expiratory Pressure Elevation For Lung Recruitment in Acute Respiratory Distress Syndrome (ARDS) No drug interventions treatment Not Available completed NCT04023305
Sevoflurane PharmacokInetics in ARDS treatment Not Available terminated NCT04935697
Non-invasive Vagal Neurostimulation (nVNS) for Traumatic Brain Injury (TBI)-Induced Acute Respiratory Distress No drug interventions treatment Not Available recruiting NCT04641897
Impact of Decreasing Respiratory Rate on Lung Injury Biomarkers in ARDS Patients No drug interventions prevention Not Available completed NCT05514483
5-HT3 Receptor Antagonist and Respiratory Drive in Patients With ARDS treatment 4 recruiting NCT01680783
Non-Invasive Ventilation Via a Helmet Device for Patients Respiratory Failure No drug interventions treatment Not Available completed NCT00538161
Effect of Low Tidal Volume Ventilation in Improving Oxygenation and Thus Reducing Acute Lung Injury in the Cardiac Surgical Patient No drug interventions prevention Not Available completed NCT04737161
Safety of T Regulatory Cell Therapy in Subjects With COVID-19 Induced Acute Respiratory Distress Syndrome No drug interventions treatment 1 withdrawn NCT05583461
Ventilator-induced Right Ventricular Injury During EIT-based PEEP Titration in Patients With ARDS No drug interventions diagnostic Not Available recruiting NCT04987528
Pulmonary Fibrosis During Severe COVID-19 Pneumonia No drug interventions Not Available Not Available active_not_recruiting NCT02867228
Noninvasive Estimation of Work of Breathing No drug interventions diagnostic Not Available terminated NCT05816928
Ventilation-Perfusion Matching in Early-stage Prone Position Ventilation No drug interventions Not Available Not Available completed NCT00538928
Extrapulmonary Interventional Ventilatory Support in Severe Acute Respiratory Distress Syndrome (ARDS) No drug interventions treatment Not Available completed NCT03621293
Long Term Outcome on Brain and Lung of Different Oxygen Strategies in ARDS Patients No drug interventions treatment 3 unknown_status NCT00343993
Noninvasive Positive Pressure Ventilation for ALI/ARDS:a Multicentre Randomized Controlled Trial No drug interventions treatment 1 unknown_status NCT04371393
MSCs in COVID-19 ARDS treatment 3 terminated NCT01096771
The Effect of Intravenous Lipids on Lung Function in Acute Respiratory Distress Syndrome (ARDS) treatment 2 terminated NCT02967471
Discovery of New Early Detection Biomarkers From Peripheral Blood of Acute Respiratory Distress Syndrome(ARDS) No drug interventions Not Available Not Available unknown_status NCT02596178
Titration of PEEP During Mechanical Ventilation in Patients With ARDS Using Electrical Impedance Tomography. No drug interventions treatment Not Available withdrawn NCT02509078
Reevaluation Of Systemic Early Neuromuscular Blockade treatment 3 completed NCT06051188
FCV vs PCV in Moderate to Severe ARDS No drug interventions treatment Not Available recruiting NCT03969407
Determination of the Best Positive End-expiratory Pressure (PEEP) No drug interventions Not Available Not Available completed NCT03736707
Selective High Frequency Oscillatory Ventilation (HFOV) for Neonates No drug interventions treatment Not Available withdrawn NCT03303807
Correction by ECCO2-R of Hypercapnia in Patients With DVP in Moderate to Severe ARDS Under Protective Ventilation. No drug interventions prevention Not Available completed NCT03379207
Innate Immune Response During Community Acquired Pneumonia No drug interventions Not Available Not Available recruiting NCT04865107
Cellular Immuno-Therapy for COVID-19 ARDS Randomized Clinical Trial treatment 2 unknown_status NCT05180409
Assessment of Microcirculation Alteration With Both Sublingual Microcirculation and Near-infrared Spectroscopy on ARDS No drug interventions Not Available Not Available unknown_status NCT03255109
WorldwidE AssessmeNt of Separation of pAtients From Ventilatory assistancE No drug interventions Not Available Not Available completed NCT03513809
Inflammation and Distribution of Pulmonary Ventilation Before and After Tracheal Intubation in ARDS Patients No drug interventions Not Available Not Available unknown_status NCT04312009
Losartan for Patients With COVID-19 Requiring Hospitalization treatment 2 completed NCT04115709
Decision Support System to Evaluate VENTilation in ARDS No drug interventions diagnostic Not Available completed NCT04524156
COVID-19 : Transcutaneous pO2 and pCO2 as Predictive Factors for Acute Respiratory Destress Syndrome in Patients Affected With SARS-Cov-2 No drug interventions basic_science Not Available unknown_status NCT05387356
Evaluation of the Efficiency and Complications of the Consequtive Proning in Covid -19 ICU No drug interventions Not Available Not Available unknown_status NCT03465085
Streptokinase Versus Unfractionated Heparin Nebulization in Severe ARDS treatment 3 completed NCT03004885
Enhanced Lung Protective Ventilation for ARDS Patients With PrismaLung No drug interventions supportive_care Not Available terminated NCT05886985
Safety, Tolerability, and Efficacy of MatriPlax in Subjects With Acute Respiratory Distress Syndrome No drug interventions treatment 1 not_yet_recruiting NCT04365985
Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19 treatment 2 terminated NCT00789685
Safety, Tolerability and Preliminary Efficacy of FP-1201 in ALI and ARDS. Phase I/II treatment 1 / 2 completed NCT04325685
The Effect of Supraglottic and Oropharyngeal Decontamination on the Incidence of Ventilator-associated Pneumonia prevention Not Available completed NCT00958685
Safety Study of Feeding With Ginger Extract in Acute Respiratory Distress Syndrome No drug interventions treatment 2 completed NCT02490215
Epidemiology of Acute Respiratory Distress Syndrome in Chinese ICUs No drug interventions Not Available Not Available completed NCT01573715
Effects of Neuromuscular Blocking Agents (NMBA) on the Alteration of Transpulmonary Pressures at the Early Phase of Acute Respiratory Distress Syndrome (ARDS) treatment 4 unknown_status NCT00980915
Timing and Intensity of the Exposures and Attributable Burden of Acute Lung Injury No drug interventions Not Available Not Available completed NCT05166915
Respiratory COVID-19: A Randomized, Sham-Controlled Study No drug interventions treatment Not Available withdrawn NCT03085615
Feeding the Critically Ill During Phases of Altered Redox Status No drug interventions supportive_care Not Available completed NCT06039215
Paramedical Protocol for Ventilation in Acute Respiratory Distress Syndrome No drug interventions treatment Not Available not_yet_recruiting NCT03719937
Artificial Increase in Chest Wall Elastance as an Alternative to Prone Positioning in Moderate-to-severe ARDS. No drug interventions treatment Not Available suspended NCT02387437
Different Effects of Three Recruitment Maneuvers on the Lung Heterogeneity of Acute Respiratory Distress Syndrome No drug interventions treatment Not Available unknown_status NCT01927237
Pulmonary Vascular Effects of Respiratory Rate & Carbon Dioxide No drug interventions basic_science Not Available withdrawn NCT03654352
The ASTERS Study: Assessing the Role of Sphingolipids in AcuTE Respiratory Distress Syndrome (ARDS) No drug interventions Not Available Not Available completed NCT01284452
Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) treatment Not Available completed NCT04390152
Safety and Efficacy of Intravenous Wharton's Jelly Derived Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome Due to COVID 19 No drug interventions treatment 1 / 2 terminated NCT04373200
Human Ab Response & immunoMONItoring of COVID-19 Patients No drug interventions other Not Available completed NCT02816359
Position and Esophageal Pressure No drug interventions diagnostic Not Available completed NCT02889770
Dead Space Monitoring With Volumetric Capnography in ARDS Patients No drug interventions Not Available Not Available completed NCT05238870
Prevention of Skin Damage in the Patient in Prone Position: Development of Education Interventions Based on a Training Needs Assessment Study. No drug interventions Not Available Not Available completed NCT05406570
Personalized Tidal Volume in ARDS (VT4HEMOD) No drug interventions treatment Not Available recruiting NCT05451342
Explore Potential Plasma and BALF Immunometabolic and Lipidomic Biomarkers for Identifying ARDS Endotypes No drug interventions Not Available Not Available unknown_status NCT00682942
How to Predict Lung Recruitment at the Bedside in Patients Affected by Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) No drug interventions Not Available Not Available completed NCT01522599
Flow-flow ECCO2-R and 4 ml/kg Tidal Volume vs. 6 ml/kg Tidal Volume to Enhance Protection From VILI in Acute Lung Injury No drug interventions treatment 3 terminated NCT01757899
Effects and Safety of Infusion of Low-Doses of Methylprednisolone in Early ALI and ARDS in Children treatment 2 withdrawn NCT04657406
Expanded Access to Zofin for Patients With COVID-19 Not Available Not Available available NCT00446706
Estimation of Intrinsic Positive End-Expiratory Pressure (PEEP) in Acute Respiratory Distress Syndrome (ARDS) No drug interventions Not Available Not Available completed NCT03971006
Immune Alveolar Alterations During Pneumonia-Associated Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available unknown_status NCT00970606
STIP: Statin Trial for Influenza Patients treatment Not Available terminated NCT04370249
Construction of a Composite Clinical-echo Score Predictive of a Risk of Short-term Aggravation of Respiratory Impairment in Patients Suspected of Covid-19 No drug interventions Not Available Not Available completed NCT01768949
Echocardiography Predictive of the Inefficacy and/or of the Unsafeness of Recruitment Maneuvers in Patients With Acute Respiratory Distress Syndrome. No drug interventions screening Not Available completed NCT05531149
Efficacy and Safety of Trimodulin (BT588) in Subjects With CAP Including COVID-19 Pneumonia No drug interventions treatment 3 recruiting NCT04565249
Evaluation of the Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Participants With Acute Respiratory Distress Syndrome (ARDS) Associated With at Least Severe COVID-19 treatment 2 terminated NCT04388813
Predictors of Severe COVID-19 Outcomes No drug interventions Not Available Not Available completed NCT04699513
The Effect of Preemptive APRV on Patients With High Risk for ARDS No drug interventions prevention Not Available completed NCT00149513
Post-Hospital Case Management to Improve Clinical Outcomes in Individuals Requiring Mechanical Ventilation No drug interventions treatment Not Available completed NCT00527813
Effect of Prone Positioning on Mortality in Patients With Severe and Persistent Acute Respiratory Distress Syndrome No drug interventions supportive_care Not Available completed NCT00005318
ARDS - Clinical Epidemiology and the Role of the Inflammatory Response - SCOR in Acute Lung Injury No drug interventions Not Available Not Available completed NCT03425318
Continuous Negative Abdominal Pressure in ARDS (CNAP in ARDS) No drug interventions supportive_care Not Available recruiting NCT04972318
Two Different Ventilatory Strategies in Acute Respiratory Distress Syndrome Due to Community-acquired Pneumonia No drug interventions treatment Not Available terminated NCT04349618
Ultraprotective Ventilation Without Extracorporeal Circulation During COVID 19 Pneumonia No drug interventions treatment Not Available unknown_status NCT06013319
Effect of Esmolol on Oxygenation Index in Patients With Acute Respiratory Distress Syndrome treatment 3 recruiting NCT00673517
The Effect of High Frequency Oscillation on Biological Markers of Lung Injury No drug interventions Not Available Not Available completed NCT01478217
PEEP Recruitment-comparison Between Ultrasonographic Assessment and LIP Assessment No drug interventions Not Available Not Available completed NCT04405817
Outcome of Patients Treated With ECLS No drug interventions Not Available Not Available recruiting NCT05258617
Low-Level Laser Therapy Treatment of Lung Inflammation in Post-COVID-19 Recovery No drug interventions Not Available Not Available terminated NCT05855317
Association Between the Level of EV-TF and the Occurence of Pulmonary Embolism in Patients With ARDS No drug interventions Not Available Not Available recruiting NCT04113434
Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available active_not_recruiting NCT01666834
Cross-section Survey of Mechanical Ventilation and Acute Respiratory Distress Syndrome in China No drug interventions Not Available Not Available completed NCT05801224
Vascular ARDS Recruitment After Inhaled Nitric Oxide No drug interventions diagnostic Not Available recruiting NCT04798716
The Use of Exosomes for the Treatment of Acute Respiratory Distress Syndrome or Novel Coronavirus Pneumonia Caused by COVID-19 No drug interventions treatment 1 / 2 not_yet_recruiting NCT06038916
To Evaluate The Safety and Initial Efficacy of STSA-1002 Injection in Patients With Acute Respiratory Distress Syndrome No drug interventions treatment 1 / 2 recruiting NCT04371016
Pulmonary and Ventilatory Effects of Bed Verticalization in Patients With Acute Respiratory Distress Syndrome No drug interventions treatment Not Available completed NCT03591796
Invasive Ventilation for Neonates With Acute Respiratory Distress Syndrome(ARDS) No drug interventions treatment Not Available withdrawn NCT05608096
European Registry for Hemadsorption in Sepsis With the Seraph Filter No drug interventions Not Available Not Available recruiting NCT03132896
Re-Evaluation of Systemic Early Neuromuscular Blockade and Transthoracic Ultrasound Assessment of the Diaphragm No drug interventions Not Available Not Available withdrawn NCT05474196
Association Between Driving Transpulmonary Pressure and Extravascular Lung Water in Patients With ARDS No drug interventions Not Available Not Available recruiting NCT01519258
Mechanical Ventilation With Neurally-Adjusted Ventilatory Assist in Patients With ARDS No drug interventions treatment Not Available completed NCT00773058
Effect of Treatment With Stress-Doses Glucocorticoid in Patients With Acute Respiratory Distress Syndrome (ARDS) treatment 4 unknown_status NCT00188058
Comparison of 2 Strategies of Adjustment of Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome No drug interventions treatment Not Available completed NCT04442958
Effectiveness of Convalescent Immune Plasma Therapy No drug interventions treatment Not Available completed NCT04435535
Chest Physiotherapy in Tracheotomized Patients No drug interventions treatment Not Available completed NCT05198986
Pronation During Veno-venous Extra Corporeal Membrane Oxygenation No drug interventions Not Available Not Available unknown_status NCT04335786
Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVID-19) Infection Disease treatment 4 terminated NCT04616586
SILtuximab in Viral ARds (SILVAR) Study treatment 3 terminated NCT03051139
A Strategy to Improve Implementation of LTVV for Patients w/ ARDS No drug interventions health_services_research Not Available withdrawn NCT06181539
Evaluate the Effect of Prone Ventilation on Ventilated-blood Flow Ratio in Patients With ARDS by EIT No drug interventions Not Available Not Available recruiting NCT04457739
Assessment of Preload Responsiveness in ARDS Patients During Prone Position No drug interventions Not Available Not Available completed NCT04358939
Prone Position in Patients on High-flow Nasal Oxygen Therapy for COVID-19 (HIGH-PRONE-COVID-19) No drug interventions treatment Not Available completed NCT01757522
Detection of Right Ventricular Dysfunction by 2D Strain During Acute Respiratory Distress Syndrom (ARDS) No drug interventions Not Available Not Available completed NCT01585922
Noninvasive Positive Pressure Ventilation in Moderate Acute Respiratory Distress Syndrome No drug interventions treatment Not Available completed NCT00521625
Epidemiologic Multicenter Study on Mechanical Ventilation Management in Children With Acute Lung Injury No drug interventions Not Available Not Available completed NCT04870125
Safety Study of Inhaled Carbon Monoxide to Treat Pneumonia and Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS) treatment 1 active_not_recruiting NCT05767125
Effect of APRV and LTV on Lung Ventilation and Perfusion in Patients With Moderate-to-severe ARDS No drug interventions treatment Not Available recruiting NCT04352725
Effect of PEEP Titration on the EELV Measured by the Nitrogen Dilution Technique in ARDS No drug interventions supportive_care Not Available unknown_status NCT03372525
Invasive Ventilation Strategies for Neonates With Acute Respiratory Distress Syndrome Syndrome (ARDS) No drug interventions treatment Not Available recruiting NCT02711930
Effect of Prone Positioning on Intra-ocular Pressure in ARDS Patients No drug interventions Not Available Not Available completed NCT04357730
Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection treatment 2 completed NCT04383730
Inhaled Sedation in COVID-19-related Acute Respiratory Distress Syndrome (ISCA): an International Research Data Study in the Recent Context of Widespread Disease Resulting From the 2019 (SARS-CoV2) Coronavirus Pandemics (COVID-19) No drug interventions Not Available Not Available completed NCT06037330
Nalbuphine in ARDS Patients After Surgery treatment 4 recruiting NCT03662230
Incidence and Severity of Acute Respiratory Distress Syndrome (ARDS) in the French Wounded Soldiers No drug interventions Not Available Not Available completed NCT04660448
Lung Ultrasound Score and Pediatric Intensive Care Outcomes (LUS-PICO) No drug interventions Not Available Not Available completed NCT06233448
Thorathic Fluid Content as an Early Predictor of Weaning From Mechanical Ventilation in Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available not_yet_recruiting NCT02598648
Role and Molecular Mechanism of Farnesoid X Receptor(FXR) and RIPK3 in the Formation of Acute Respiratory Distress Syndrome in Neonates No drug interventions diagnostic Not Available recruiting NCT04402957
LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID-19) treatment 2 completed NCT02582957
Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress Syndrome No drug interventions prevention Not Available completed NCT05692557
Virtual Reality Distraction Technique to Improve Chest Burns With Acute Respiratory Distress Syndrome No drug interventions treatment Not Available completed NCT04208126
Early Versus Late Initiation of ECMO (Extracorporal Membrane Oxygenation) Trial (ELIEO-Trial) No drug interventions treatment Not Available not_yet_recruiting NCT04361526
Pilot Study on Cytokine Filtration in COVID-19 ARDS No drug interventions treatment Not Available unknown_status NCT02003326
Strain and Blood Inflammatory Markers as Prognostic Tools for ARDS AMIS (ARDS - Markers of Inflammation - Strain) No drug interventions other Not Available terminated NCT06308926
MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS Patients No drug interventions treatment 2 not_yet_recruiting NCT01314066
Efficacy of Bevacizumab in Preventing Acute Respiratory Distress Syndrome (ARDS) prevention 2 withdrawn NCT06069466
Epidemiological Characteristics and Prediction System of Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available enrolling_by_invitation NCT01239966
Pulmonary And Renal Support During Acute Respiratory Distress Syndrome No drug interventions supportive_care 3 completed NCT05697666
Impact of the Depth of Neuromuscular Blockade on Respiratory Mechanics in Moderate to Severe ARDS Patients No drug interventions Not Available Not Available completed NCT01704066
Interobserver Variation in Applying a Radiographic Definition for Acute Respiratory Distress Syndrome (ARDS) No drug interventions Not Available Not Available completed NCT05677165
The Relationship Between Driving Pressure, Mechanical Power, Oxygenation and Saturation Indices: Retrospective Observational Study No drug interventions Not Available Not Available completed NCT00000574
Ibuprofen in Sepsis Study treatment 3 completed NCT04241874
PEEP and Spontaneous Breathing During ARDS No drug interventions treatment Not Available completed NCT01775774
Human Mesenchymal Stem Cells For Acute Respiratory Distress Syndrome treatment 1 completed NCT04184674
Impact of the Transpulmonary Pressure on Right Ventricle Function in Acute Respiratory Distress Syndrome No drug interventions other Not Available completed NCT03351920
Ventilation's Parameters Applied in Emergency Medicine. A Prospective Observational Study No drug interventions Not Available Not Available completed NCT04386720
Measurement of Airway Opening Pressure (AOP) in Patients With Acute Respiratory Distress Syndrom and With or Without Covid 19. No drug interventions Not Available Not Available completed NCT04378920
A Study of Liposomal Trans Crocetin, LEAF-4L6715, in Patients With Acute Respiratory Distress Syndrome Due to COVID-19, Sepsis or Other Causes No drug interventions treatment 1 / 2 completed NCT02178982
Standard Treatment Compliance of Participants, Effectiveness and Prognosis in Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT00440882
Changes of Transforming Growth Factor b1 and Procollagen III in Patients With Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT01078831
Intrabronchial Airway Pressures in Intubated Patients During Bronchoscopy No drug interventions Not Available Not Available completed NCT05372731
Recruitment Maneuver After Bronchoalveolar Lavage in ARDS Patients No drug interventions other Not Available not_yet_recruiting NCT05922631
Effect of APRV vs. LTV on Right Heart Function in ARDS Patients: a Single-center Randomized Controlled Study No drug interventions treatment Not Available unknown_status NCT05259631
Inhalational (Sevoflurane) Versus Intravenous (Propofol) Sedation in Adults With a Moderate Form of ARDS treatment 3 suspended NCT02010073
Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE No drug interventions Not Available Not Available completed NCT01450527
Etiology and Outcomes of Tropical Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT04401527
Treatment of Lung Injury From COVID-19 Infection With Intravenous Sodium Nitrite treatment 2 withdrawn NCT04358627
Dexmedetomidine to Improve Outcomes of ARDS in Critical Care COVID-19 Patients Not Available Not Available unknown_status NCT06113276
Quantitative Computed Tomography for Mortality Risk Stratification in ARDS No drug interventions Not Available Not Available recruiting NCT03504176
Pediatric Acute Respiratory Distress Syndrome Ventilation Bundle No drug interventions Not Available Not Available completed NCT00142376
Short Term Outcomes of Children With Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT04663776
Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-Based Study Platform No drug interventions Not Available Not Available completed NCT04777760
Surfactant for Neonatal Respiratory Distress Syndrome(NRDS) and Neonatal Acute Respiratory Distress Syndrome(NARDS) No drug interventions Not Available Not Available recruiting NCT01899560
ELASTANCE: Prospective Physiological Study of Lung Elastance in Recruitment and Derecruitment in Early Onset Mechanically Ventilated ARDS Patients No drug interventions supportive_care 3 completed NCT04659460
RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective Randomized Pilot Study No drug interventions treatment Not Available unknown_status NCT02814994
Respiratory System Compliance Guided VT in Moderate to Severe ARDS Patients No drug interventions treatment Not Available completed NCT04443491
Comparison of Esophageal and Central Venous Pressure for Estimating Transpulmonary Pressure Changes No drug interventions Not Available Not Available completed NCT04451291
Study of Decidual Stromal Cells to Treat COVID-19 Respiratory Failure treatment Not Available completed NCT00127491
Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury No drug interventions treatment Not Available completed NCT02895191
The Safety and Dose Response Relationship of Ulinastatin for Acute Respiratory Distress Syndrome(ARDS) treatment 2 unknown_status NCT05600062
Influence of NEP Inhibition on Vascular Leak and Inflammation (NEPi-INFLAMMATION) basic_science Not Available recruiting NCT04524962
Study of Descartes-30 in Acute Respiratory Distress Syndrome treatment 1 terminated NCT04350580
Polyvalent Immunoglobulin in COVID-19 Related ARds treatment 3 completed NCT06357780
Closed-loop syncHronization vErsuS convenTional Synchronization in sPontaneously Breathing Adult Nonivasive ventilationPatients No drug interventions treatment Not Available not_yet_recruiting NCT02027129
Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO No drug interventions diagnostic 1 completed NCT00811629
Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients No drug interventions Not Available Not Available completed NCT03415529
Impact of Arterial CO2 Tension on Management and Outcome in Patients With Acute Hypoxemic Respirator Failure and ARDS No drug interventions Not Available Not Available completed NCT03946189
Comparison of the PaO2/FiO2 Ratio to Other Oxygenation Indexes for the Classification of Severity of Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT03920189
Echocardiographic Evaluation in ARDS Patients No drug interventions Not Available Not Available completed NCT04844892
Phrenic Nerve Stimulation-Induced Lung ReAeration Trial No drug interventions treatment Not Available completed NCT06051292
Decremental Esophageal Catheter Filling Volume Titration For Transpulmonary Pressure Measurement No drug interventions treatment Not Available recruiting NCT05978544
Safety and Preliminary Clinical Activity of Itolizumab in ARDS treatment 1 not_yet_recruiting NCT02836444
Stratification of the Acute Respiratory Distress Syndrome - A Second Phase Study No drug interventions Not Available Not Available completed NCT04708340
Tolerability and Efficacy of RJX in Patients With COVID-19 treatment 1 / 2 unknown_status NCT04954040
Prevention and Treatment With Hydroxychloroquine + Azithromycin of Acute Respiratory Syndrome Induced by COVID-19 treatment 2 unknown_status NCT02606240
Low-Flow CO2 Removal for Mild to Moderate ARDS With PRISMALUNG No drug interventions Not Available Not Available completed NCT02064140
Supported Ventilation in ARDS Patients prevention Not Available completed NCT06148467
Reverse Trigger Phenotypification and Response to Ventilatory Adjustments No drug interventions Not Available Not Available recruiting NCT02253667
Palliative Use of High-flow Oxygen Nasal Cannula in End-of-life Lung Disease Patients No drug interventions supportive_care Not Available withdrawn NCT01161901
Impact of Inflammation Biomarkers on the Acute Respiratory Distress Syndrome (ARDS) Definition No drug interventions Not Available Not Available completed NCT04345601
Mesenchymal Stromal Cells for the Treatment of SARS-CoV-2 Induced Acute Respiratory Failure (COVID-19 Disease) treatment 1 / 2 completed NCT04327401
COVID-19-associated ARDS Treated With Dexamethasone: Alliance Covid-19 Brasil III treatment 3 terminated NCT03766204
The Role of Circulating CircRNAs and MicroRNAs in Acute Lung Injury No drug interventions Not Available Not Available recruiting NCT04530604
Defibrotide Therapy for SARS-CoV2 (COVID-19) Acute Respiratory Distress Syndrome (ARDS) treatment 1 completed NCT02492204
The Role of IL33/ST2 Axis in ARDS Patients No drug interventions Not Available Not Available completed NCT04385004
Clinical, Biological and Histological Pulmonary and Renal Damage Associated With the SARS-CoV-2 Syndrome in Patients Admitted in ICU No drug interventions Not Available Not Available unknown_status NCT06020404
Prone Position in infantS/Children With Acute Respiratory Distress Syndrome No drug interventions other Not Available recruiting NCT01301872
Effect of Mechanical Ventilation Strategy on Lung Injury in Patients With Less Severe Acute Respiratory Distress Syndrome: Targeted on RAGE No drug interventions Not Available Not Available unknown_status NCT02816372
Ultra Protective Ventilation Without Extracorporeal Circulation in Severe ARDS Patients (VT4ARDS) No drug interventions treatment Not Available completed NCT00000572
Extracorporeal Carbon Dioxide Removal for Acute Respiratory Distress Syndrome No drug interventions treatment 3 completed NCT06413472
Comparing Formulations of Mechanical Power Using Geometric Methods No drug interventions Not Available Not Available active_not_recruiting NCT00281268
Fluids and Catheters Treatment Trial (FACTT) - ARDS Clinical Research Network No drug interventions treatment 3 completed NCT04411368
Impact of Respiratory Virus in Critically Ill Patients With Acute Respiratory Failure No drug interventions Not Available Not Available unknown_status NCT00295269
Corticosteroids as Rescue Therapy for the Late Phase of Acute Respiratory Distress Syndrome No drug interventions treatment 3 completed NCT05922969
Safety of Low PEEP Maneuvers During ARDS Management No drug interventions Not Available Not Available recruiting NCT04369469
Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe Pneumonia treatment 3 terminated NCT05401812
Glucocorticoid Therapy for Acute Respiratory Distress Syndrome No drug interventions treatment 2 unknown_status NCT03112512
A Comparison of Optimal PEEP Determination Guided by EIT and G5 Device in Moderate and Severe ARDS Patients No drug interventions supportive_care Not Available completed NCT02027181
Automatic Administration of Oxygen During Respiratory Distress No drug interventions treatment 1 completed NCT01274481
Iloprost Effects on Gas Exchange and Pulmonary Mechanics treatment 1 completed NCT02019095
Clinical and Biological Markers in Acute Respiratory Failure No drug interventions Not Available Not Available completed NCT04517695
Blood Volume Assessment in COVID-19 and Bacterial Sepsis No drug interventions Not Available Not Available completed NCT04412395
Clinical Assessment of Oral Lactoferrin as a Safe Antiviral and Immunoregulatory in Treating COVID-19 Disease No drug interventions treatment 2 unknown_status NCT00182195
Lung Open Ventilation to Decrease Mortality in the Acute Respiratory Distress Syndrome No drug interventions treatment 3 completed NCT03096314
Vitamin D to Improve Outcomes by Leveraging Early Treatment treatment 3 completed NCT04603755
Electrical Impedance Tomography: Collapse in Dependent Areas as a Predictor of Response to Prone Position Ventilation in COVID-19 Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available completed NCT03076450
Evaluation of POC Lung Ultrasound Combined With Pressure-volume Curve to Titration Adjust PEEP for ARDS Lung Recruitment No drug interventions treatment Not Available unknown_status NCT02326350
ASpirin as a Treatment for ARDS (STAR): a Phase 2 Randomised Control Trial treatment 2 terminated NCT05224323
Avalanche Phenomenon During Airways Opening in Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available unknown_status NCT06387823
Efficacy and Safety of Sivelestat Sodium and Dexamethasone in the Treatment of ARDS treatment Not Available recruiting NCT02468908
Inhaled Molgramostim (rhGM-CSF) in Healthy Adult Subjects treatment 1 completed NCT04068038
Pediatric Acute Respiratory Distress Syndrome Asia Study No drug interventions Not Available Not Available completed NCT02365038
ART-2 Pilot - Driving Pressure Limited Ventilation for Patients With ARDS No drug interventions treatment 1 / 2 completed NCT04609943
Study to Find the Highest Safe Dose of Soluble Guanylate Cyclase (sGC) Activator, BAY 1211163 Administered as Multiple Doses by Inhalation to Patients Who Cannot Breathe by Their Own and Suffer From a Type of Lung Failure That Causes Fluid to Build up in the Lungs Making Breathing Difficult (ARDS) No drug interventions treatment 1 terminated NCT05535543
Change in the Phase III Slope of the Volumetric Capnography by Prone Positioning in Acute Respiratory Distress Syndrome No drug interventions Not Available Not Available recruiting NCT03042143
Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration (REALIST) No drug interventions treatment 1 / 2 active_not_recruiting