Major depressive disorder, recurrent episode

Also known as: Treatment-resistant Depression / Depression NOS / Major depressive illness / Major depression / Major depressive disorder NOS / Depressive Disorder, Major / Major depressive disorder, recurrent episode, unspecified degree

DrugDrug NameDrug Description
DB00334OlanzapineAn antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.
DrugDrug NameTargetType
DB00334OlanzapineDopamine D1 receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M1target
DB00334OlanzapineMuscarinic acetylcholine receptor M3target
DB00334Olanzapine5-hydroxytryptamine receptor 2Atarget
DB00334OlanzapineDopamine D4 receptortarget
DB00334OlanzapineHistamine H1 receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M4target
DB00334OlanzapineMuscarinic acetylcholine receptor M2target
DB00334OlanzapineDopamine D2 receptortarget
DB00334Olanzapine5-hydroxytryptamine receptor 2Ctarget
DB00334OlanzapineDopamine D3 receptortarget
DB00334OlanzapineAlpha-1B adrenergic receptortarget
DB00334OlanzapineCytochrome P450 1A2enzyme
DB00334Olanzapine5-hydroxytryptamine receptor 3Atarget
DB00334Olanzapine5-hydroxytryptamine receptor 6target
DB00334OlanzapineAlpha-1A adrenergic receptortarget
DB00334OlanzapineDopamine D5 receptortarget
DB00334OlanzapineSerum albumincarrier
DB00334OlanzapineAlpha-1-acid glycoprotein 1carrier
DB00334OlanzapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00334OlanzapineCytochrome P450 2D6enzyme
DB00334OlanzapineP-glycoprotein 1transporter
DB00334OlanzapineCytochrome P450 2C19enzyme
DB00334OlanzapineD(1) dopamine receptortarget
DB00334OlanzapineBeta adrenergic receptortarget
DB00334Olanzapine5-hydroxytryptamine receptor 1target
DB00334OlanzapineGABA(A) Receptor Benzodiazepine Binding Sitetarget
DB00334OlanzapineCytochrome P450 2C9enzyme
DB00334OlanzapineUDP-glucuronosyltransferase 1-4enzyme
DB00334OlanzapineCytochrome P450 3A4enzyme
DB00334OlanzapineCytochrome P450 3A Subfamilyenzyme
DrugDrug NamePhaseStatusCount
DB01221Ketamine0Enrolling by Invitation1
DB01221Ketamine0Not Yet Recruiting1
DB00083Botulinum toxin type A1Not Yet Recruiting1
DB12675PF-049952741Unknown Status1
DB00818Propofol1Recruiting1
DB09153Sodium chloride1Not Yet Recruiting1
DB140105-methoxy-N,N-dimethyltryptamine1 / 2Recruiting1
DB00514Dextromethorphan1 / 2Recruiting1
DB01488Dimethyltryptamine1 / 2Recruiting1
DB00945Acetylsalicylic acid2Recruiting1
DB05205CX1572Completed1
DB00753Isoflurane2Not Yet Recruiting1
DB01221Ketamine2Completed3
DB01221Ketamine2Terminated1
DB01221Ketamine2Unknown Status1
DB01221Ketamine2Withdrawn1
DB14509Lithium carbonate2Withdrawn1
DB00683Midazolam2Completed1
DB02701Nicotinamide2Not Yet Recruiting1
DB06690Nitrous oxide2Completed1
DB11664Psilocybin2Not Yet Recruiting1
DB11664Psilocybin2Recruiting4
DB00936Salicylic acid2Recruiting1
DB01104Sertraline2Not Yet Recruiting1
DB16304TAK-6532Withdrawn1
DB01221Ketamine2 / 3Completed1
DB01221Ketamine2 / 3Recruiting1
DB00683Midazolam2 / 3Completed1
DB00818Propofol2 / 3Recruiting1
DB00818Propofol2 / 3Withdrawn1
DB01156Bupropion3Completed1
DB00514Dextromethorphan3Completed1
DB00476Duloxetine3Completed3
DB01175Escitalopram3Completed3
DB11823Esketamine3Completed3
DB11823Esketamine3Not Yet Recruiting1
DB00472Fluoxetine3Completed1
DB00472Fluoxetine3Terminated1
DB01221Ketamine3Recruiting1
DB14509Lithium carbonate3Completed1
DB01017Minocycline3Recruiting1
DB00334Olanzapine3Completed1
DB00334Olanzapine3Terminated1
DB01224Quetiapine3Completed1
DB01104Sertraline3Completed3
DB00641Simvastatin3Recruiting1
DB00285Venlafaxine3Completed4
DB01238Aripiprazole4Recruiting1
DB00297Bupivacaine4Not Yet Recruiting1
DB01156Bupropion4Recruiting1
DB09061Cannabidiol4Not Yet Recruiting1
DB00260Cycloserine4Unknown Status1
DB01221Ketamine4Completed1
DB01221Ketamine4Recruiting2
DB01221Ketamine4Unknown Status1
DB01221Ketamine4Withdrawn1
DB14509Lithium carbonate4Recruiting1
DB00540Nortriptyline4Recruiting1
DB11062Octisalate4Not Yet Recruiting1
DB09535Octocrylene4Not Yet Recruiting1
DB00818Propofol4Completed1
DB00734Risperidone4Withdrawn1
DB09289Tianeptine4Recruiting1
DB09321Zinc oxide4Not Yet Recruiting1
DB00321AmitriptylineNot AvailableUnknown Status1
DB01156BupropionNot AvailableUnknown Status1
DB00215CitalopramNot AvailableUnknown Status1
DB01242ClomipramineNot AvailableUnknown Status1
DB00476DuloxetineNot AvailableUnknown Status1
DB01175EscitalopramNot AvailableUnknown Status1
DB11823EsketamineNot AvailableRecruiting1
DB00472FluoxetineNot AvailableUnknown Status1
DB00176FluvoxamineNot AvailableUnknown Status1
DB00458ImipramineNot AvailableUnknown Status1
DB01221KetamineNot AvailableCompleted2
DB01221KetamineNot AvailableNot Yet Recruiting1
DB01221KetamineNot AvailableRecruiting2
DB14509Lithium carbonateNot AvailableUnknown Status1
DB00683MidazolamNot AvailableCompleted1
DB00370MirtazapineNot AvailableUnknown Status1
DB06690Nitrous oxideNot AvailableRecruiting1
DB00540NortriptylineNot AvailableUnknown Status1
DB09140OxygenNot AvailableRecruiting1
DB00715ParoxetineNot AvailableUnknown Status1
DB00734RisperidoneNot AvailableUnknown Status1
DB08839SerotoninNot AvailableRecruiting1
DB01104SertralineNot AvailableUnknown Status1
DB00391SulpirideNot AvailableUnknown Status1
DB00752TranylcypromineNot AvailableUnknown Status1
DB00656TrazodoneNot AvailableUnknown Status1
DB00285VenlafaxineNot AvailableUnknown Status1