Catecholamines

Name
Catecholamines
Accession Number
DBCAT000467
Description

A general class of ortho-dihydroxyphenylalkylamines derived from tyrosine.

Drugs
DrugDrug Description
NorepinephrineA sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest.
EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
DopamineA catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension.
CarbidopaA dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms.
DipivefrinA prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma.
OrciprenalineA beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD.
DobutamineA beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery.
MethyldopaA centrally-acting alpha-2 adrenergic agonist used to manage hypertension alone or in combination with hydrochlorothiazide, and to treat hypertensive crises.
IsoprenalineA catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block.
LevodopaA dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism.
6-hydroxydopa quinoneNot Available
EtilevodopaInvestigated for use/treatment in parkinson's disease.
LevonordefrinA topical sympathomimetic amine found in local anesthetic products that is used for nasal decongestion or vasoconstriction during dental procedures.
ProtokylolProtokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.
RacepinephrineA bronchodilator used to treat intermittent asthma.
DopexamineDopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer.
DichloroisoproterenolDichloroisoproterenol has been used in trials studying the treatment and basic science of Insulin Resistance and Polycystic Ovary Syndrome.
ReproterolA short-acting β2 adrenoreceptor agonist used to treat various types of asthma including allergic asthma, non-allergic asthma, and exercise-induced asthma.
TheodrenalineTheodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
MelevodopaA methyl ester of levodopa indicated in combination with carbidopa for the treatment of Parkinson's disease.
IbopamineA sympathomimetic, indicated in the induction of mydriasis and treatment of pos-surgical ocular hypotonia.
AdrenaloneNot Annotated
DeoxyepinephrineSympathomimetic, vasoconstrictor agent.
DroxidopaA medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease.
DebrisoquineFor the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.
Fluorodopa (18F)Fluorodopa F 18 is indicated for use with positron emission tomography (PET) to visualize dopaminergic nerve terminals in the striatum for the evaluation of adult patients with suspected Parkinsonian syndromes...
DopastatinDopastatin is under investigation in clinical trial NCT04335357 (TBR-760 in Adult Patients With Non-functioning Pituitary Adenomas).
N-oleoyldopamineN-oleoyldopamine (OLDA) is an amide of dopamine and oleic acid.
DocarpamineNot Available
Drugs & Drug Targets
DrugTargetType
NorepinephrinePhenylalanine-4-hydroxylasetarget
NorepinephrineAlpha-1A adrenergic receptortarget
NorepinephrineAlpha-1B adrenergic receptortarget
NorepinephrineAlpha-1D adrenergic receptortarget
NorepinephrineAlpha-2A adrenergic receptortarget
NorepinephrineAlpha-2B adrenergic receptortarget
NorepinephrineAlpha-2C adrenergic receptortarget
NorepinephrineBeta-1 adrenergic receptortarget
NorepinephrineBeta-2 adrenergic receptortarget
NorepinephrineBeta-3 adrenergic receptortarget
NorepinephrineSolute carrier family 22 member 2transporter
NorepinephrineSolute carrier family 22 member 3transporter
NorepinephrineOrganic cation/carnitine transporter 2transporter
NorepinephrineSolute carrier family 22 member 1transporter
NorepinephrinePOU domain, class 5, transcription factor 1transporter
NorepinephrineSodium-dependent noradrenaline transportertransporter
NorepinephrineSynaptic vesicular amine transportertarget
NorepinephrineChromaffin granule amine transportertarget
EpinephrineAlpha-1A adrenergic receptortarget
EpinephrineBeta-1 adrenergic receptortarget
EpinephrineBeta-2 adrenergic receptortarget
EpinephrineSolute carrier family 22 member 2transporter
EpinephrineSolute carrier family 22 member 1transporter
EpinephrineCytochrome P450 2C9enzyme
EpinephrineCytochrome P450 3A4enzyme
EpinephrineAlpha-1B adrenergic receptortarget
EpinephrineAlpha-1D adrenergic receptortarget
EpinephrineAlpha-2A adrenergic receptortarget
EpinephrineAlpha-2B adrenergic receptortarget
EpinephrineTumor necrosis factortarget
EpinephrineCatechol O-methyltransferaseenzyme
EpinephrineMonoamine oxidaseenzyme
DopamineD(1A) dopamine receptortarget
DopamineDopamine beta-hydroxylasetarget
DopamineAmine oxidase [flavin-containing] Aenzyme
DopamineAmine oxidase [flavin-containing] Benzyme
DopamineCatechol O-methyltransferaseenzyme
DopamineSolute carrier family 22 member 2transporter
DopamineSolute carrier family 22 member 1transporter
DopamineSolute carrier family 22 member 3transporter
DopamineOrganic cation/carnitine transporter 2transporter
DopaminePOU domain, class 5, transcription factor 1transporter
DopamineD(1B) dopamine receptortarget
DopamineD(2) dopamine receptortarget
DopamineD(3) dopamine receptortarget
DopamineD(4) dopamine receptortarget
DopamineSodium-dependent dopamine transportertarget
DopamineDopamine beta-hydroxylaseenzyme
Dopamine5-hydroxytryptamine receptor 1Atarget
Dopamine5-hydroxytryptamine receptor 7target
DopamineD(1) dopamine receptortarget
DopamineSodium-dependent noradrenaline transportertarget
DopamineSodium-dependent serotonin transportertarget
Dopamine5-hydroxytryptamine receptor 3Atarget
Dopamine5-hydroxytryptamine receptor 3Btarget
DopamineSuperoxide dismutase [Cu-Zn]target
DopamineSynaptic vesicular amine transportertarget
CarbidopaAromatic-L-amino-acid decarboxylasetarget
DipivefrinAlpha-2A adrenergic receptortarget
DipivefrinCholinesterasetarget
DipivefrinBeta-2 adrenergic receptortarget
DipivefrinAlpha-1A adrenergic receptortarget
DipivefrinAcetylcholinesterasetarget
DipivefrinBeta-1 adrenergic receptortarget
OrciprenalineBeta-2 adrenergic receptortarget
DobutamineBeta-1 adrenergic receptortarget
DobutamineCatechol O-methyltransferaseenzyme
DobutamineBeta-2 adrenergic receptortarget
DobutamineAlpha-1 adrenergic receptorstarget
DobutamineEstrogen receptortarget
MethyldopaAlpha-2A adrenergic receptortarget
MethyldopaCatechol O-methyltransferaseenzyme
MethyldopaSolute carrier family 15 member 1transporter
MethyldopaAromatic-L-amino-acid decarboxylasetarget
MethyldopaAlbumincarrier
MethyldopaSulfotransferaseenzyme
MethyldopaDopamine beta-hydroxylaseenzyme
MethyldopaPhenylethanolamine N-methyltransferaseenzyme
MethyldopaAromatic-L-amino-acid decarboxylaseenzyme
MethyldopaD(2) dopamine receptortarget
IsoprenalineBeta-1 adrenergic receptortarget
IsoprenalineBeta-2 adrenergic receptortarget
IsoprenalineBeta-3 adrenergic receptortarget
IsoprenalineCytochrome P450 1A1enzyme
IsoprenalineSuperoxide dismutase [Cu-Zn]target
IsoprenalineCytochrome P450 1B1enzyme
IsoprenalineAlbumincarrier
IsoprenalineCatechol O-methyltransferaseenzyme
IsoprenalineCholinesteraseenzyme
IsoprenalineInterleukin-12 subunit betatarget
LevodopaD(1A) dopamine receptortarget
LevodopaD(2) dopamine receptortarget
LevodopaAromatic-L-amino-acid decarboxylaseenzyme
LevodopaSolute carrier family 15 member 1transporter
LevodopaMonocarboxylate transporter 10transporter
LevodopaD(3) dopamine receptortarget
LevodopaD(4) dopamine receptortarget
LevodopaD(1B) dopamine receptortarget
LevodopaLarge neutral amino acids transporter small subunit 1transporter
LevodopaLarge neutral amino acids transporter small subunit 2transporter
LevodopaAlbumincarrier
6-hydroxydopa quinoneAmine oxidase [copper-containing] 3target
6-hydroxydopa quinonePrimary amine oxidasetarget
6-hydroxydopa quinonePhenylethylamine oxidasetarget
LevonordefrinAlpha-2 adrenergic receptorstarget
LevonordefrinAlpha-1D adrenergic receptortarget
LevonordefrinAlpha-1B adrenergic receptortarget
LevonordefrinAlpha-1A adrenergic receptortarget
ProtokylolBeta-2 adrenergic receptortarget
ProtokylolBeta-1 adrenergic receptortarget
RacepinephrineAlpha-1A adrenergic receptortarget
RacepinephrineAlpha-1B adrenergic receptortarget
RacepinephrineAlpha-2A adrenergic receptortarget
RacepinephrineAlpha-2B adrenergic receptortarget
RacepinephrineAlpha-2C adrenergic receptortarget
RacepinephrineBeta-1 adrenergic receptortarget
RacepinephrineBeta-2 adrenergic receptortarget
RacepinephrineAlpha-1D adrenergic receptortarget
RacepinephrineBeta-3 adrenergic receptortarget
DopexamineD(2) dopamine receptortarget
DichloroisoproterenolBeta-2 adrenergic receptortarget
DichloroisoproterenolBeta-1 adrenergic receptortarget
DroxidopaPhenylalanine-4-hydroxylasetarget
DroxidopaAlpha-1A adrenergic receptortarget
DroxidopaAlpha-1B adrenergic receptortarget
DroxidopaAlpha-1D adrenergic receptortarget
DroxidopaAlpha-2A adrenergic receptortarget
DroxidopaAlpha-2B adrenergic receptortarget
DroxidopaAlpha-2C adrenergic receptortarget
DroxidopaBeta-1 adrenergic receptortarget
DroxidopaBeta-2 adrenergic receptortarget
DroxidopaBeta-3 adrenergic receptortarget
DroxidopaAromatic-L-amino-acid decarboxylaseenzyme
DroxidopaMonocarboxylate transporter 10transporter
DroxidopaSodium-dependent noradrenaline transportertransporter
DebrisoquineSodium-dependent noradrenaline transportertarget
DebrisoquineCytochrome P450 2D6enzyme
DebrisoquineATP-dependent translocase ABCB1transporter
DebrisoquineCytochrome P450 1A1enzyme
Fluorodopa (18F)Aromatic-L-amino-acid decarboxylaseenzyme
N-oleoyldopamineLethal factortarget
DocarpamineD(2) dopamine receptortarget