Sugar Alcohols

Name
Sugar Alcohols
Accession Number
DBCAT000648
Description

Polyhydric alcohols having no more than one hydroxy group attached to each carbon atom. They are formed by the reduction of the carbonyl group of a sugar to a hydroxyl group.(From Dorland, 28th ed)

Drugs
DrugDrug Description
MannitolA sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis.
Isosorbide mononitrateA nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease.
SorbitolA product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener.
XylitolAn ingredient added to dental products to remove bacteria.
InositolAn ingredient found in a variety of nutritional products.
RibitolNot Annotated
ErythritolErythritol is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.
DithioerythritolA compound that, along with its isomer, Cleland's reagent (dithiothreitol), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl...
DiatrizoateAn injected contrast agent used in radiology.
Gadobenic acidA gadolinium compound used as a contrast agent in MRIs.
Isosorbide dinitrateA vasodilator used to treat angina in coronary artery disease.
Erythrityl tetranitrateFor the prevention of angina.
1D-myo-inositol 1,3,4-trisphosphateNot Available
Glycerol 2-phosphateNot Available
2-Deoxy-D-Glucitol 6-(E)-VinylhomophosphonateNot Available
Inositol 1,3,4,5-TetrakisphosphateNot Available
2,5-Dideoxy-2,5-Imino-D-GlucitolNot Available
GhavamiolNot Available
Inositol 1,3-BisphosphateNot Available
scyllo-inositolAn isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been...
1D-myo-inositol 1,4,5-trisphosphateIntracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the...
2,3-di-O-phytanyl-sn-glycerolNot Available
MonothioglycerolNot Available
Inositol 2,4,5-trisphosphateNot Available
Indole-3-Glycerol PhosphateNot Available
Choline alfoscerateA natural choline that is used to manage declining cognitive function associated with neurodegenerative and vascular diseases.
VogliboseAn alpha-glucosidase inhibitor indicated in the management of postprandial blood glucose in patients with type II diabetes.
Glycerol phenylbutyrateA nitrogen-binding agent used to manage patients with urea cycle disorders who cannot be sufficiently managed amino acid supplementation and/or dietary restrictions.
Gadoteric acidA diagnostic contrast agent used with magnetic resonance imaging to provide contrast enhancement for intracranial and spinal lesions with abnormal blood brain barrier or abnormal vascularity, and for whole body imaging.
Iothalamic acidA diagnostic contrast agent used in various medical imaging procedures, such as angiography, arthrography, and computed tomographic scans.
MeglumineAn amino sugar found in iodinated contrast media.
GlycerinIt is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
Sodium glycerophosphateA medication used to treat hypophosphatemia.
Calcium glycerophosphateAn medication used to treat low levels of phosphate or calcium, as well as an ingredient in dental products to prevent dental caries.
LuseogliflozinAn SGLT2 inhibitor used to manage type 2 diabetes mellitus.
DianhydrogalactitolDianhydrogalactitol has been used in trials studying the treatment of GBM, Glioma, Glioblastoma, Brain Cancer, and Glioblastoma Multiforme.
MitolactolMitolactol has been used in trials studying the treatment of Brain and Central Nervous System Tumors.
MethylinositolMethylinositol has been used in trials studying the treatment of Dementia and Alzheimer's Disease.
Ioxitalamic acidA contrast agent used for CT scans of the abdomen and pelvis.
MitobronitolNot Annotated
Meglumine antimoniateNot Annotated
Iocarmic acidNot Annotated
EthylhexylglycerinAn emollient solvent with antimicrobial activity.
Phytic acidPhytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications).
LicogliflozinLicogliflozin is under investigation in clinical trial NCT03320941 (A Dose-finding Study to Evaluate the Change in Weight After Treatment With LIK066 in Japanese Patients With Obesity).
SomapacitanA human growth hormone analog subcutaneous injection indicated for adults with growth hormone deficiency.
VB-201VB-201 is under investigation in clinical trial NCT01001468 (Study to Assess VB-201 in Patients With Psoriasis).
Drugs & Drug Targets
DrugTargetType
MannitolMannitol dehydrogenaseenzyme
Isosorbide mononitrateGuanylate cyclase soluble subunit alpha-2target
Isosorbide mononitrateGlutathione S-transferase Mu 1enzyme
Isosorbide mononitrateXanthine dehydrogenase/oxidaseenzyme
Isosorbide mononitrateAlcohol dehydrogenase class-3enzyme
XylitolXylose isomerasetarget
XylitolXylose isomerasetarget
XylitolXylose isomerasetarget
XylitolXylose isomerasetarget
XylitolHyaluronate lyasetarget
InositolSodium/myo-inositol cotransportertransporter
Erythritol5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferasetarget
DithioerythritolListeriolysin regulatory proteintarget
Dithioerythritol6,7-dimethyl-8-ribityllumazine synthasetarget
DithioerythritolThymidine kinase, cytosolictarget
Gadobenic acidSerum albumincarrier
Isosorbide dinitrateAtrial natriuretic peptide receptor 1target
Isosorbide dinitrateCytochrome P450 2E1enzyme
Erythrityl tetranitrateAtrial natriuretic peptide receptor 1target
Erythrityl tetranitrateAtrial natriuretic peptide receptor 2target
Glycerol 2-phosphateTriosephosphate isomerasetarget
2-Deoxy-D-Glucitol 6-(E)-VinylhomophosphonateInositol-3-phosphate synthase 1target
Inositol 1,3,4,5-TetrakisphosphateRAC-alpha serine/threonine-protein kinasetarget
Inositol 1,3,4,5-TetrakisphosphatePleckstrin homology domain-containing family A member 4target
Inositol 1,3,4,5-TetrakisphosphateTyrosine-protein kinase BTKtarget
Inositol 1,3,4,5-TetrakisphosphateDual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositidetarget
Inositol 1,3,4,5-TetrakisphosphateInositol-trisphosphate 3-kinase Atarget
Inositol 1,3,4,5-TetrakisphosphateCytohesin-2target
Inositol 1,3,4,5-TetrakisphosphateCytohesin-3target
Inositol 1,3,4,5-Tetrakisphosphate3-phosphoinositide-dependent protein kinase 1target
2,5-Dideoxy-2,5-Imino-D-GlucitolXylose isomerasetarget
GhavamiolAlpha-mannosidase 2target
Inositol 1,3-BisphosphateEarly endosome antigen 1target
scyllo-inositolGlucosylceramidasetarget
scyllo-inositol1-phosphatidylinositol phosphodiesterasetarget
scyllo-inositolCDP-diacylglycerol--inositol 3-phosphatidyltransferasetarget
scyllo-inositol1-phosphatidylinositol phosphodiesterasetarget
1D-myo-inositol 1,4,5-trisphosphateCytohesin-2target
1D-myo-inositol 1,4,5-trisphosphateEpsin-1target
1D-myo-inositol 1,4,5-trisphosphate1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1target
1D-myo-inositol 1,4,5-trisphosphateRadixintarget
1D-myo-inositol 1,4,5-trisphosphateSpectrin beta chain, non-erythrocytic 1target
1D-myo-inositol 1,4,5-trisphosphateInositol 1,4,5-trisphosphate receptor type 1target
1D-myo-inositol 1,4,5-trisphosphateInositol-trisphosphate 3-kinase Atarget
MonothioglycerolProlyl endopeptidasetarget
Inositol 2,4,5-trisphosphate1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1target
Indole-3-Glycerol PhosphateTryptophan synthase alpha chaintarget
Indole-3-Glycerol PhosphateTryptophan synthase beta chaintarget
Choline alfoscerateGanglioside GM2 activatortarget
VogliboseMaltase-glucoamylase, intestinaltarget
Glycerol phenylbutyratePancreatic triacylglycerol lipaseenzyme
Glycerol phenylbutyrateCytochrome P450 3A4enzyme
Glycerol phenylbutyrateCytochrome P450 2D6enzyme
GlycerinGroup IIE secretory phospholipase A2target
GlycerinInositol-3-phosphate synthase 1target
GlycerinAlcohol dehydrogenase 1Btarget
GlycerinInositol 1,4,5-trisphosphate receptor type 1target
GlycerinGlycodelintarget
GlycerinAlpha-N-acetylgalactosaminidasetarget
GlycerinADP-ribosylation factor 1target
GlycerinBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1target
GlycerinDNA mismatch repair protein MutLtarget
GlycerinRibonucleoside-diphosphate reductase 1 subunit betatarget
GlycerinA/G-specific adenine glycosylasetarget
GlycerintRNA (cytosine(38)-C(5))-methyltransferasetarget
GlycerinCytochrome P450 2E1enzyme
GlycerinRetinal dehydrogenase 1enzyme
GlycerinPeroxisome proliferator-activated receptor deltatarget
GlycerinMaleylacetoacetate isomerasetarget
GlycerinAquaporin-7transporter
GlycerinAquaporin-9transporter
GlycerinGlycerol uptake facilitator proteintransporter
SomapacitanCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
SomapacitanCytochrome P450 2C12, female-specificenzyme
SomapacitanCytochrome P450 1A2enzyme
SomapacitanCytochrome P450 2C19enzyme
SomapacitanSerum albumincarrier
SomapacitanGrowth hormone receptortarget