Raynaud's Phenomenon (DBCOND0040958)

Identifiers

Synonyms
Raynaud’s phenomenon / Raynaud’s syndrome / Raynaud's Syndrome / Raynaud Syndrome / Raynaud / Raynaud's Disease / Raynaud phenomenon / Raynaud's phenomenon / Raynauds / Raynaud Disease / Raynauds disease / Raynaud's phenomenon (disorder) / Secondary Raynaud's phenomenon (disorder) / Raynaud's disease (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Alprostadil
A prostaglandin E1 agonist used for the treatment of erectile dysfunction and as an adjunct for its diagnosis.
Captopril
An ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy.
Cinnarizine
A drug used for the management of labyrinthine disorder symptoms, including vertigo, tinnitus, nystagmus, nausea, and vomiting.
Isoxsuprine
A beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease.
No drug targets
Nifedipine
A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
Prazosin
An alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05204784
Rheopheresis for Raynaud's and Digital Ulcers in Systemic SclerosisNo drug interventionstreatmentNot Availableunknown_status
NCT03749577
Nutritional Strategies to Increase Nitric Oxide Signaling in Raynaud's PhenomenonNo drug interventionstreatmentNot Availableunknown_status
NCT04015193
Follow-up of SPTS in Patients With Raynaud's PhenomenonNo drug interventionsNot AvailableNot Availablerecruiting
NCT03129178
Beet the Cold: The Effect of Inorganic Nitrate Supplementation in Individuals With Raynaud's PhenomenonNo drug interventionstreatmentNot Availablecompleted
NCT06291142
Early Diagnosis of SSc in the General Rheumatology Clinic - PilotNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT04898036
Phototherapy For Treatment Of Raynaud's PhenomenonNo drug interventionstreatmentNot Availablewithdrawn
NCT03639766
The Effect of Abobotulinum Toxin A on the Symptoms of Raynaud's Phenomenontreatment4terminated
NCT01280266
Efficacy Study of PDE-5 Inhibitor and Calcium Channel Inhibitor for the Treatment of Secondary Raynaud Phenomenontreatment2 / 3completed
NCT04388176
Cold Challenge With C21 in RPNo drug interventionstreatment2completed
NCT03094910
Investigation of the Rewarming og the Fingers After Cooling and the Autonomic Nervous System in Raynaud's PhenomenonNo drug interventionsdiagnosticNot Availablecompleted
NCT04644523
Dermoscopy in Primary Raynaud's PhenomenonNo drug interventionsNot AvailableNot Availablecompleted
NCT01347008
Effect of Sildenafil on the Microcirculatory Blood Flow and Endothelial Progenitor Cells in Systemic Sclerosistreatment3completed
NCT03869008
Potential Benefit for Non Invasive Vagus Nerve Stimulation Using GammaCore in the Treatment of Raynaud's Phenomena.No drug interventionstreatmentNot Availableterminated
NCT03699436
Effectiveness of Electric Stimulation Therapy in Raynaud's PhenomenonNo drug interventionstreatmentNot Availablecompleted
NCT03984422
Application for Monitoring and Evaluation of Raynaud's PhenomenonNo drug interventionsNot AvailableNot Availablerecruiting
NCT03393325
Tadalafil-Delivra and Raynaud's PhenomenonNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03972566
Localized Effects of PBM and Exogenous NO on CREST Patients Calcinosis Cutis & Raynaud PhenomenonNot AvailableNot Availableunknown_status
NCT05125029
Botulinum Toxin in Raynaud's PhenomenonNo drug interventionstreatment4recruiting
NCT04854850
Apollo Device for Fatigue in Systemic SclerosisNo drug interventionstreatmentNot Availablecompleted
NCT03059979
The Effect of High Dose Methylprednisolone on Nailfold in Early Systemic Sclerosis ( SSc )No drug interventionstreatment0unknown_status
NCT02396238
Scleroderma Treatment With Celution Processed Adipose Derived Regenerative Cells (STAR)No drug interventionstreatmentNot Availablecompleted
NCT03058887
The Effects of Exercise in Patients With Systemic SclerosisNo drug interventionsotherNot Availablecompleted
NCT01117298
A Randomized Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in Sclerodermatreatment3completed
NCT00700518
Dose Response to Topical Glyceryl Trinitrate in Patients With Raynaud's Phenomenontreatment1completed
NCT02583789
Assess Efficacy of of Oral Treprostinil in Patients With Symptomatic Primary or Secondary Raynaud's Phenomenontreatment0completed
NCT02506062
A Trial of Ischemic Preconditioning in Raynaud's Phenomenon (RP)No drug interventionstreatmentNot Availablecompleted
NCT02050360
"As Required" Oral Sildenafil in Raynaud's Phenomenontreatment2 / 3completed
NCT01378845
Prognostic Influence of Light Rheography Measurement of Patients With Secondary Raynaud Syndrome With Ulcers on HandspreventionNot Availableunknown_status
NCT01315899
Efficacy of ORM-12741 for Prevention of Raynaud's PhenomenonNo drug interventionsprevention2terminated
NCT00841594
MQX-503 Applied to the Hand Versus Nitroglycerin Ointment Applied to the Chest: A Pharmacokinetic Comparisontreatment1completed
NCT00946738
The Effect of Physical Therapy on Raynaud's Phenomenon Secondary to Systemic SclerosisNo drug interventionstreatmentNot Availablecompleted
NCT02165111
Efficacy of Botulinum Toxin In Scleroderma-Associated Raynaud's Syndrometreatment3completed
NCT01233999
Botulinum Toxin in the Treatment of Raynaud'streatmentNot Availablecompleted
NCT01291199
Effects of Vardenafil on Clinical Symptoms and Peripheral Blood Flow in Patients With Raynaud's Syndrometreatment2 / 3completed
NCT05698979
Evaluation of Botulinum TOXin Type A in the Treatment of Buerger's Diseasetreatment3not_yet_recruiting
NCT03941184
Spontaneous Coronary Artery Dissection (SCAD) and AutoimmunityNo drug interventionsNot AvailableNot Availablecompleted
NCT00822354
Tadalafil for the Treatment of Raynaud'streatmentNot Availablecompleted
NCT00498615
A Rho-kinase Inhibitor (Fasudil) in the Treatment of Raynaud's Phenomenontreatment3completed
NCT02680509
Single-port Thoracoscopic Sympathicotomy for Treatment of Raynaud's Phenomenon, a Feasibility StudyNo drug interventionstreatmentNot Availablecompleted
NCT02615964
Nova Cold Hands Raynaud's Disorder, a Disease Which Results in Decreased Blood Flow to the Hands and Feet.No drug interventionsNot AvailableNot Availablecompleted
NCT00378521
Dose Response Study of a Topical Gel for the Treatment of Raynaud's PhenomenonNo drug interventionstreatment2completed
NCT00419419
Phase III Study of a Topical Gel Formulation for Treatment and Prevention of Raynaud's Phenomenontreatment3completed
NCT01090492
PF-00489791 For The Treatment Of Raynaud'streatment2completed
NCT00577304
A Study of a Topical Form of Nitroglycerin and Placebo in the Treatment and Prevention of Raynaud's Phenomenontreatment3unknown_status
NCT02683408
Diosmiplex (Vasculera®) in Primary and Secondary Raynaud's PhenomenonNo drug interventionspreventionNot Availablecompleted
NCT01309802
A Two-Part Study of BOTOX® Therapy for Ischemic Digitstreatment2completed
NCT00480753
Dose Response Study of a Topical Formulation of Nitroglycerin for the Treatment of Raynaud's Phenomenontreatment2completed
NCT00528242
Safety, Tolerability, and Pharmacodynamic Profile of Oral 2101 in Secondary Raynaud's Diseasetreatment2completed
NCT00351117
St. John's Wort in the Treatment of Raynaud's Phenomenontreatment3completed
NCT00048763
Safety and Efficacy of Pletal(Cilostazol) for the Treatment of Juvenile Primary and Secondary Raynaud's Phenomenontreatment4completed
NCT00000530
Raynaud's Treatment Study (RTS)treatment3completed
NCT00048776
Safety and Efficacy of Pletal (Cilostazol) for the Treatment of Juvenile Primary and Secondary Raynaud's Phenomenontreatment4completed
NCT00266669
Phase III Study of Topical Gel for Treatment and Prevention of Raynaud's Phenomenontreatment3completed
NCT02183779
PORH and Response to Cold in Raynaud's Phenomenon.No drug interventionsbasic_scienceNot Availableunknown_status
NCT02298777
Metabolomic Analysis of Systemic SclerosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT01926847
Digital Flow Enhancement in Raynaud's Phenomenon With an sGC (Soluble Guanylate Cyclase) StimulatorNot Available2completed
NCT00004786
Phase III Randomized, Double-Blind, Placebo-Controlled Study of Oral Iloprost for Raynaud's Phenomenon Secondary to Systemic Sclerosistreatment3completed
NCT03027674
Topical 10 % Nifedipine Versus 5% Sildenafil in Secondary Raynaudtreatment0completed
NCT02374320
Exparel as a Nerve Block for Severe Hand Paintreatment2 / 3terminated
NCT00934427
Study of a Topical Formulation for the Treatment and Prevention of Raynaud's Phenomenon Symptomstreatment3unknown_status
NCT01743612
Laser Speckle Contrast Imaging for Cutaneous Microvascular Dysfunction Detection in Systemic Sclerosis.No drug interventionsNot AvailableNot Availablecompleted
NCT00626665
Randomised Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in Sclerodermatreatment3completed
NCT00253331
Lab Study of MQX-503 in Treatment of Raynaud'sprevention2 / 3completed
NCT02642146
Treatment of Digital Ulcers in Korean Patients With Systemic Sclerosis: a Prospective Cohort StudyNot AvailableNot Availableterminated
NCT00251238
Efficacy and Tolerability of Ginkgo Biloba Extract in Patients With Raynaud´s Phenomenondiagnostic2completed