Estrogen Antagonists
- Name
- Estrogen Antagonists
- Accession Number
- DBCAT000786
- Description
Compounds which inhibit or antagonize the biosynthesis or action of estradiol.
- Drugs
Drug Drug Description Afimoxifene For the potential treatment of menstrual-cycle related mastalgia, fibrocystic breast disease, breast disease, gynecomastia and Keloid scarring. Aminoglutethimide An adrenocortical steroid synthesis inhibitor used in the treatment of Cushing's syndrome. Anastrozole A competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women. Clomifene A medication used to induce ovulation. Danazol A synthetic steroid and pituitary gonadotropin inhibitor used in the treatment of endometriosis and symptomatic treatment of severe pain and tenderness associated with benign fibrocystic breasts. Droloxifene Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor modulator (SERM). Droloxifene also exhibits more rapid pharmacokinetics, reaching peak concentrations and being eliminated much more... Enclomiphene Not Annotated Exemestane An aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen. Fadrozole Not Annotated Formestane For the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Fulvestrant An estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-. Hydroxyprogesterone caproate A synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth. ICI-164384 Not Available Idoxifene Idoxifene is a small molecule drug. Idoxifene has a monoisotopic molecular weight of 523.14 Da. Letrozole An aromatase inhibitor used to treat breast cancer in postmenopausal women. Mepitiostane Mepitiostane is a small molecule drug. Mepitiostane has a monoisotopic molecular weight of 404.27 Da. Moxestrol Not Annotated Nafoxidine Nafoxidine is a small molecule drug. Nafoxidine has a monoisotopic molecular weight of 425.24 Da. Naringenin Not Available Ormeloxifene A selective estrogen receptor modulator used as a non-hormonal, non-steroidal oral contraceptive. Plomestane Plomestane is a small molecule drug. The usage of the INN stem '-mestane' in the name indicates that Plomestane is a aromatase inhibitor. Plomestane has a monoisotopic molecular weight of... Raloxifene A selective estrogen receptor modulator that is used to prevent and treat osteoporosis and reduce the risk of invasive breast cancer in high-risk postmenopausal women. Tamoxifen A selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women. Vorozole Not Annotated - Drugs & Drug Targets