Emphysema

Also known as: Bullous emphysema (lung)(pulmonary) / Pulmonary Emphysema / Emphysema pulmonary

DrugDrug NameDrug Description
DB00058Alpha-1-proteinase inhibitorA purified form of human alpha-1 proteinase inhibitor used to treat emphysema patients with associated alpha-1 proteinase inhibitor deficiency.
DB01408BambuterolFor the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.
DB00651DyphyllineA theophylline derivative used to treat asthma, bronchospasm, and COPD.
DB00588Fluticasone propionateA glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
DB00874GuaifenesinAn expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses.
DB00332IpratropiumAn anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD).
DB01366ProcaterolA beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
DB01001SalbutamolA beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms.
DB00871TerbutalineA beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.
DB00277TheophyllineA xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
DB01409TiotropiumA long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).
DrugDrug NameTargetType
DB00058Alpha-1-proteinase inhibitorNeutrophil elastasetarget
DB01408BambuterolBeta-2 adrenergic receptortarget
DB01408BambuterolCholinesteraseenzyme
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB00651DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB00651DyphyllineAdenosine receptor A1target
DB00651DyphyllineAdenosine receptor A2atarget
DB00588Fluticasone propionateCorticosteroid-binding globulincarrier
DB00588Fluticasone propionateCytosolic phospholipase A2target
DB00588Fluticasone propionateGlucocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A4enzyme
DB00588Fluticasone propionateProgesterone receptortarget
DB00588Fluticasone propionateMineralocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A5enzyme
DB00588Fluticasone propionateCytochrome P450 3A7enzyme
DB00588Fluticasone propionateCytochrome P450 2C8enzyme
DB00588Fluticasone propionateSolute carrier organic anion transporter family member 1B1carrier
DB00588Fluticasone propionateP-glycoprotein 1transporter
DB00588Fluticasone propionateSolute carrier organic anion transporter family member 1B1transporter
DB00874GuaifenesinNMDA receptortarget
DB00332IpratropiumMuscarinic acetylcholine receptor M1target
DB00332IpratropiumMuscarinic acetylcholine receptor M2target
DB00332IpratropiumMuscarinic acetylcholine receptor M3target
DB00332IpratropiumSolute carrier family 22 member 5transporter
DB00332IpratropiumSolute carrier family 22 member 4transporter
DB00332IpratropiumSerum albumincarrier
DB00332Ipratropiumalpha1-acid glycoproteincarrier
DB01366ProcaterolBeta-2 adrenergic receptortarget
DB01001SalbutamolBeta-2 adrenergic receptortarget
DB01001SalbutamolBeta-1 adrenergic receptortarget
DB01001SalbutamolCytochrome P450 3A4enzyme
DB01001SalbutamolBeta-3 adrenergic receptortarget
DB00871TerbutalineBeta-2 adrenergic receptortarget
DB00871TerbutalineCholinesteraseenzyme
DB00871TerbutalineBeta-3 adrenergic receptortarget
DB00871TerbutalineBeta-1 adrenergic receptortarget
DB00277TheophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB00277TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00277TheophyllineAdenosine receptor A2btarget
DB00277TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00277TheophyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00277TheophyllineAdenosine receptor A1target
DB00277TheophyllineAdenosine receptor A2atarget
DB00277TheophyllineCytochrome P450 1A2enzyme
DB00277TheophyllineAdenosine deaminaseenzyme
DB00277TheophyllineCytochrome P450 2E1enzyme
DB00277TheophyllineCytochrome P450 3A4enzyme
DB00277TheophyllineSolute carrier family 22 member 7transporter
DB00277TheophyllineCytochrome P450 1A1enzyme
DB00277TheophyllineCytochrome P450 1B1enzyme
DB00277TheophyllineCytochrome P450 2D6enzyme
DB00277TheophyllineHistone deacetylase 2target
DB00277TheophyllineCopine-1target
DB00277TheophyllineMinor histocompatibility antigen H13target
DB00277TheophyllineNodal modulator 1target
DB00277TheophyllinePoly [ADP-ribose] polymerase 1target
DB00277TheophyllineProtein RIC-3target
DB00277TheophyllineTubulin monoglycylase TTLL3target
DB01409TiotropiumMuscarinic acetylcholine receptor M3target
DB01409TiotropiumCytochrome P450 2D6enzyme
DB01409TiotropiumCytochrome P450 3A4enzyme
DB01409TiotropiumMuscarinic acetylcholine receptor M1target
DB01409TiotropiumMuscarinic acetylcholine receptor M2target
DB01409TiotropiumSolute carrier family 22 member 5transporter
DB01409TiotropiumSolute carrier family 22 member 4transporter
DB01409TiotropiumMuscarinic acetylcholine receptor M4target
DB01409TiotropiumMuscarinic acetylcholine receptor M5target
DrugDrug NamePhaseStatusCount
DB09155Helium0Unknown Status1
DB00556Perflutren0Unknown Status1
DB11104Sulfur hexafluoride0Unknown Status1
DB13453Xenon0Unknown Status1
DB15726Human Umbilical Cord Mesenchymal Stem Cells1Completed1
DB09140Oxygen1Completed1
DB00945Acetylsalicylic acid2Active Not Recruiting1
DB00058Alpha-1-proteinase inhibitor2Completed1
DB11863Alvelestat2Recruiting1
DB08879Belimumab2Recruiting1
DB08818Hyaluronic acid2Completed1
DB01050Ibuprofen2Completed1
DB00203Sildenafil2Completed1
DB00755Tretinoin2Completed1
DB01274Arformoterol3Completed3
DB00074Basiliximab3Completed1
DB01222Budesonide3Unknown Status1
DB00983Formoterol3Completed2
DB00983Formoterol3Unknown Status1
DB00938Salmeterol3Completed2
DB00058Alpha-1-proteinase inhibitor4Completed2
DB01274Arformoterol4Completed1
DB01274Arformoterol4Unknown Status1
DB00394Beclomethasone dipropionate4Unknown Status1
DB13867Fluticasone4Completed1
DB00983Formoterol4Unknown Status1
DB00983Formoterol4Withdrawn1
DB00678Losartan4Active Not Recruiting1
DB00678Losartan4Completed1
DB09140Oxygen4Recruiting1
DB01656Roflumilast4Completed1
DB00938Salmeterol4Unknown Status1
DB00203Sildenafil4Completed1
DB00203Sildenafil4Recruiting2
DB00641Simvastatin4Unknown Status1
DB01409Tiotropium4Completed1
DB01409Tiotropium4Unknown Status1
DB00254DoxycyclineNot AvailableActive Not Recruiting1
DB13867FluticasoneNot AvailableTerminated1
DB01001SalbutamolNot AvailableCompleted1
DB01001SalbutamolNot AvailableUnknown Status1
DB00938SalmeterolNot AvailableTerminated1
DB01409TiotropiumNot AvailableCompleted1
DB01409TiotropiumNot AvailableUnknown Status1